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    • 2. 发明申请
    • 7-OXOPROSTACYCLINE DERIVATIVES AND PROCESS FOR THEIR MANUFACTURE
    • 7-氧羰基胆碱衍生物及其制备方法
    • WO1987005900A1
    • 1987-10-08
    • PCT/DE1987000132
    • 1987-03-25
    • MAAS, Sybille (heiress of MASS, Manfred ...SCHERING AKTIENGESELLSCHAFTVORBRÜGGEN, HelmutSTÜRZEBECHER, Claus-Steffen
    • MAAS, Sybille (heiress of MASS, Manfred ...SCHERING AKTIENGESELLSCHAFTMAAS, Manfred (deceased)
    • C07D307/935
    • C07D307/937
    • 7-oxoprostacyline derivatives of Formula (I) wherein R1 is the residue OR3, in which R3 can be hydrogen or possibly alkyl substituted by halogen, phenyl, C1-C4-alkoxy or C1-C4-dialkylamino with 1-10 C atoms, or the residue NHR4 in the form of an alkanoyl or alkane sulphonyl residue each with 1-10 C atoms; W is a hydroxy methylene or a group (II), in which the OH group may be esterified with a benzoyl or alkane acid residue with 1-4 C atoms or etherified with a tetrahydropyranyl, tetrahydrofuranyl, (C1-C4 alkoxy)-C1-C4-alkyl or tri-(C1-C4-alkyl)-sylyl residue, whereby the free OH-group can be in the alpha or beta position; D is a straight-chain or branched alkylene group with 1-5 C atoms; R2 is a straight-chain or branched alkyl group with 1-6 C atoms; R5 is a hydroxygroup, which can be esterified with an alkane acid residue with 1-4 C atoms or etherified with a tetrahydropyranyl, tetrahydrofuranyl, (C1-C4-alkoxy)-C1-C4-alkyl or tri(C1-C4-alkyl) residue; X is an oxygen atom or the -CH2- residue and, if R3 is hydrogen, their salts with physiologically compatible bases, process for their production and their use as medicaments.
    • 式(I)的7-氧代前列腺素衍生物,其中R 1是残基OR 3,其中R 3可以是氢或可能被卤素,苯基,C 1 -C 4 - 烷氧基或具有1-10个C原子的C 1 -C 4二烷基氨基取代的烷基,或 残基NHR4为烷基或烷烃磺酰基残基,每个残基具有1-10个C原子; W是羟基亚甲基或基团(II),其中OH基团可以被具有1-4个C原子的苯甲酰基或烷烃酸残基酯化,或与四氢吡喃基,四氢呋喃基,(C 1 -C 4烷氧基)-C1- C 4 - 烷基或三 - (C 1 -C 4 - 烷基) - 甲苯基残基,其中游离OH基可以是α或β位; D是具有1-5个C原子的直链或支链亚烷基; R2是具有1-6个C原子的直链或支链烷基; R5是一个羟基,可以用1-4 C原子的烷烃酸残基酯化,或用四氢吡喃基,四氢呋喃基,(C 1 -C 4 - 烷氧基)-C 1 -C 4烷基或三(C 1 -C 4 - 烷基) 残留物; X是氧原子或-CH 2 - 残基,如果R 3是氢,则其与生理上相容的碱的盐,其生产过程及其用作药物。
    • 3. 发明申请
    • COATING AGENT AND METHOD OF COATING, IN PARTICULAR FOR USE ON PLASTIC SUBSTRATES
    • 盖装置和方法涂料,是塑料基板
    • WO1997022644A1
    • 1997-06-26
    • PCT/EP1996005625
    • 1996-12-14
    • HERBERTS GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNGKERBER, HermannMANN, FriedrichMASS, ManfredSTEGEN, Helga
    • HERBERTS GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
    • C08G18/62
    • C08J7/047C08G18/6283C08J7/04C08J2323/02C08J2475/00
    • The disclosure relates to a coating agent suitable in particular for use on plastic substrates and containing the following: A) 5-40 wt.% binder containing OH groups and including tertiary amino groups and/or substituted by a tertiary alkyl group; said binder being obtainable by conversion of one or more copolymers of one or more (meth)acrylic acid esters and/or (meth)acrylic amides with a tertiary amino group or an amino group substituted by a tertiary alkyl group, one or more hydroxyalkyl (meth)acrylates and one or more olefinically unsaturated compounds capable of being copolymerised and different from said hydroxyalkyl (meth)acrylates, the copolymers having a mean molecular weight (Mn) of 1500-10,000 and a glass transition temperature of between -20 and +75 DEG C, with polyisocyanates; B) 1-20 wt.% conversion products of the reaction between aromatic diglycidyl ethers and dimerised fatty acids as cross-linking agents; C) 0-30 wt.% one or more additional binders other than those of A); D) 30-70 wt.% organic solvents; E) 15-45 wt.% pigments and/or fillers; and F) 0-15 wt.% standard paint additives.
    • 对于特定的塑料基材的涂料合适的包衣剂,溶剂型,含有A)重量的OH基团的粘合剂5〜40,第三的%氨基团和/或具有由叔烷基取代的氨基基团,其由可获得 丙烯酸酯的反应的一种或一种或多种(甲基)丙烯酸酯多种共聚物和/或(甲基)含叔氨基或由取代的氨基具有叔烷基丙烯酰胺,一种或多种羟烷基(甲基)丙烯酸酯和 或其更多种不同的可共聚的烯属不饱和化合物,其共聚物的数均分子量(Mn)为1500至10,000和-20的玻璃化转变温度为75℃,与聚异氰酸酯,B)1至20重量%的反应产物 芳香族二缩水甘油基与二聚脂肪酸作为交联剂,C)0至30重量%醚蛋 网元或更多,从A)还粘合剂,D)30至不同的70重量%的一种或多种有机溶剂的%,E)15〜45重量%的颜料和/或填料和F)0至15重量% 习惯性技术涂料助剂。