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    • 2. 发明申请
    • HIGH CARBON STEEL SHEET WITH SUPERIOR HEAT TREATMENT CHARACTERISTICS, AND MANUFACTURING METHOD THEREOF
    • 具有超级热处理特性的高碳钢板及其制造方法
    • WO2010074463A8
    • 2011-03-24
    • PCT/KR2009007625
    • 2009-12-21
    • POSCOLEE CHANG-HOONJEON JEA-CHUNLEE JONG-SUBKIM KI-SOO
    • LEE CHANG-HOONJEON JEA-CHUNLEE JONG-SUBKIM KI-SOO
    • C22C38/00C21D8/02
    • C21D1/32C21D8/02C21D8/0205C21D9/46
    • The present invention provides a method for manufacturing a high carbon steel sheet, comprising the steps of i) producing a high carbon slab having a chemical composition comprising, by wt%, C 0.3-1.0%, Mn:0.1-1.2%, Si: more than 0 but less than 0.4%, Al: 0.01-0.1%, S: more than 0 but not more than 0.01%, the remainder being Fe and inevitable impurities ii) reheating the slab to the temperature higher than the Ar3 transformation point, iii) rough-milling the slab, and milling the slab again in an austenite region having a temperature higher than the Ar3 transformation point to produce a steel sheet, iv) cooling the steel sheet on a run-out table by the cooling speed of 50°C/second to 300°C/second, v) finishing the steel sheet cooling process at a temperature of 400-650°C, and maintaining the temperature, vi) winding the steel sheet at a temperature of 450-700°C, vii) omitting a pre-annealing process, and cold-rolling the wound steel sheet by a reduction ratio of 30% or higher; and viii) spheroidizing the cold-rolled steel sheet.
    • 本发明提供一种高碳钢板的制造方法,其特征在于,包括以下工序:i)制造具有化学组成的高碳钢板,所述化学成分以重量%计含有0.3〜1.0%,Mn:0.1〜1.2%,Si: 大于0但小于0.4%,Al:0.01-0.1%,S:大于0但不大于0.01%,其余为Fe和不可避免的杂质ii)将板坯加热至高于Ar3相变点的温度, iii)对板坯进行粗铣,并在温度高于Ar3相变点的奥氏体区再次研磨板坯,以产生钢板,iv)将冷却速度为50的钢板 ℃至300℃/秒,v)在400-650℃的温度下完成钢板冷却过程,并维持温度,vi)将钢板卷绕在450-700℃的温度下, vii)省略预退火工艺,并且以30%以上的压下率冷轧卷绕的钢板; 和viii)球化冷轧钢板。
    • 3. 发明申请
    • COMPOSITION CONTAINING 4-O-METHYLHONOKIOL FOR TREATING OR PREVENTING AMYLOID- RELATED DISEASES
    • 含有4-O-甲基羟基木酚醇的组合物用于治疗或预防淀粉样蛋白相关性疾病
    • WO2010036052A3
    • 2010-07-22
    • PCT/KR2009005485
    • 2009-09-25
    • BIOLAND LTDKIM KI HOKIM KI SOOKIM YOUNG HEUIKIM JIN GUKKIM KYOUNG TAEHAN CHANG SUNGLEE SANG IL
    • KIM KI HOKIM KI SOOKIM YOUNG HEUIKIM JIN GUKKIM KYOUNG TAEHAN CHANG SUNGLEE SANG IL
    • A61K31/085A23L1/29A23L1/30A61K31/05A61P25/28
    • A61K31/085A23L2/52A23L33/105A61K31/05A61K36/575
    • The present invention relates to a composition for treating or preventing amyloid-related diseases, said composition containing 4-O-methylhonokiol as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition which contains as an active ingredient and which is useful in treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorders, memory impairment, amyloidosis, etc. The inventors of the present invention first found that 4-O-methylhonokiol of the present invention inhibits the formation of beta-amyloid, and it is evidenced that 4-O-methylhonokiol can be used in the treatment and prevention of amyloid-related diseases. The inventors of the present invention have performed animal tests such as a water maze test, a passive avoidance test, and the like using experimental rats to find that 4-O-methylhonokiol is effective in the treatment or prevention of amyloid-related diseases such as Alzheimer's disease, cognitive disorders, memory impairment, amyloidosis, etc. The inventors of the prevent invention further have performed an acetylcholinesterase activity inhibition test using the cortex and hippocampus of the brain of a rat to find that 4-O-methylhonokiol is significantly effective in the treatment or prevention of Alzheimer's disease specifically from among the amyloid-related diseases.
    • 本发明涉及用于治疗或预防淀粉样蛋白相关疾病的组合物,所述组合物含有4-O-甲基和厚朴酚作为活性成分。 更具体地说,本发明涉及含有作为活性成分并可用于治疗或预防淀粉样蛋白相关疾病如阿尔茨海默病,认知障碍,记忆障碍,淀粉样变性等的药物组合物。本发明的发明人 首先发现本发明的4-O-甲基和厚朴酚抑制β-淀粉样蛋白的形成,并且证明4-O-甲基和厚朴酚可用于治疗和预防淀粉样蛋白相关疾病。 本发明的发明人使用实验大鼠进行了水迷宫试验,被动回避试验等动物试验,结果发现4-O-甲基和厚朴酚有效治疗或预防淀粉样蛋白相关疾病,例如 阿尔茨海默病,认知障碍,记忆障碍,淀粉样变性等。本发明的发明人进一步使用大鼠脑的皮质和海马进行了乙酰胆碱酯酶活性抑制试验,发现4-O-甲基和厚朴酚在 特别是从淀粉样蛋白相关疾病中治疗或预防阿尔茨海默病。
    • 5. 发明申请
    • SYSTEM FOR ELECTRONIC BUSINESS TRANSACTIONS
    • 电子商务交易系统
    • WO2008035923A1
    • 2008-03-27
    • PCT/KR2007/004571
    • 2007-09-20
    • ATTO IT CO., LTD.KANG, Kwan-sikKIM, Ki-soo
    • KANG, Kwan-sikKIM, Ki-soo
    • G06Q20/00
    • G06Q30/08G06Q20/00G06Q20/102G06Q20/204G06Q20/382
    • An electronic business transaction system is provided. The electronic business transaction system requests an ordering party to select an electronic business and input order information for the electronic business through a terminal of the ordering party, receives the order information for the electronic business from the ordering party, announces a bid for the electronic business, requests bidders to select the electronic business, input bid information for the electronic business, and organize execution groups for the electronic business through a terminal of the bidders, receives the bid information and information for the execution groups from the bidders, analyzes the bid information and the information for the execution groups, selects an order- taking party from among the bidders according to the results of the analysis, concludes an electronic contract for the electronic business between the order-taking party and the ordering party, and provides an application for processing the electronic business regarding the electronic contract to terminals of execution group members belonging to an execution group of the order- taking party so that the execution group members process the electronic business through the terminals of the execution group members.
    • 提供电子商务交易系统。 电子商务交易系统要求订购方选择电子商务,并通过订购方的终端输入电子商务的订单信息,从订购方接收电子商务的订单信息,宣布电子商务的出价 要求投标人选择电子商务,输入电子商务的投标信息,通过投标人的终端组织电子商务执行组,从投标人处收到执行组的投标信息和信息,分析出价信息 执行组的信息根据分析结果从投标人中选择订购方,订立订购方与订货方之间的电子业务电子合同,并提交申请 处理有关电子商务的电子商务 执行属于订购方的执行组的执行组成员的终端,使得执行组成员通过执行组成员的终端来处理电子业务。
    • 6. 发明申请
    • DRIVING SYSTEM
    • 驾驶系统
    • WO2008002050A1
    • 2008-01-03
    • PCT/KR2007/003078
    • 2007-06-26
    • KIM, Ki-Soo
    • KIM, Ki-Soo
    • B62D55/075
    • B62D61/12B62B5/026B62D55/075
    • A driving system that can allow a vehicle to go over or ascend obstacles or stairs through a step driving manner is provided. The driving system includes a power transmission unit connected to a main shaft connected to a power generation unit installed on the wheel frame, a plurality of driven units engaged with the power transmission unit and supporting wheels rotating by rotational force of the power transmission unit, and a carrier to which the power transmission unit and each of the driven units are operationally fixed and which goes over the obstacles by rotating when the driven units stop due to the obstacles.
    • 提供了一种驾驶系统,其可以允许车辆通过步进驱动方式越过障碍物或楼梯。 驱动系统包括连接到安装在轮架上的发电单元的主轴上的动力传递单元,与动力传递单元接合的多个从动单元和通过动力传递单元的旋转力旋转的支撑轮,以及 动力传递单元和每个从动单元可操作地固定在其上的载体,并且当被驱动单元由于障碍物停止时通过旋转而越过障碍物。
    • 8. 发明申请
    • A WHEEL CHAIR
    • 轮椅
    • WO2002096336A1
    • 2002-12-05
    • PCT/KR2002/000978
    • 2002-05-23
    • KIM, Ki-Soo
    • KIM, Ki-Soo
    • A61G5/06
    • A61G5/061A61G5/046A61G5/065A61G5/1054Y10S280/10
    • Disclosed is a wheel chair capable of going over an obstacle or ascending or descending a stair. The wheel chair comprises a wheel frame; an actuator coupled to the wheel frame; a power generating unit coupled to the actuator; a first transmission having a sun gear fixed to the power generating unit, a plurality of planet gears meshed with the sun gear, a ring gear meshed with the respective planet gears, and carriers coupled to the respective planet gears; a second transmission having a driving shaft meshed with the ring gear, a key frame rotatably installed on the driving shaft, and a casing fixed to the key frame; a plurality of front wheels each coupled to the driving shaft; a follower drivingly coupled to the driving shaft and having a follower shaft; and a rear wheel fixed to the follower shaft.
    • 公开了一种能够越过障碍物或者梯级上升或下降的轮椅。 轮椅包括轮架; 耦合到所述车轮框架的致动器; 耦合到所述致动器的发电单元; 具有固定到发电单元的太阳齿轮的第一变速器,与太阳齿轮啮合的多个行星齿轮,与相应行星齿轮啮合的齿圈以及联接到相应行星齿轮的支架; 具有与所述环形齿轮啮合的驱动轴的第二变速器,可旋转地安装在所述驱动轴上的键框和固定在所述键框上的壳体; 多个前轮,各自联接到所述驱动轴; 驱动地联接到驱动轴并具有从动轴的从动件; 以及固定在从动轴上的后轮。