专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1995019371A2 EXPRESSION OF SURFACE LAYER PROTEINS 审中-公开
标题翻译：表面层蛋白的表达
公开(公告)号：WO1995019371A2
公开(公告)日：1995-07-20
申请号：PCT/EP1995000147
申请日：1995-01-13
申请人： SOLVAY (SOCIETE ANONYME) , DEBLAERE, Rolf, Y. , DESOMER, Jan , DHAESE, Patrick
发明人： SOLVAY (SOCIETE ANONYME)
IPC分类号： C07K14/32
CPC分类号： C12N15/75 , A61K38/00 , A61K39/00 , C07K14/32 , C07K2319/00
摘要： A host cell which is provided with an S-layer comprising a fusion polypeptide consisting essentially of: (a) at least sufficient of an S-layer protein for an S-layer composed thereof to assemble, and (b) a heterologous polypeptide which is fused to either the carboxy terminus of (a) or the amino terminus of (a) and which is thereby presented on the outer surface of the said cell; can be used as a vaccine, for screening for proteins and antigens and as a support for immobilizing an enzyme, peptide or antigen.
摘要翻译：提供有S层的宿主细胞，其包含融合多肽，所述融合多肽基本上由以下组成：（a）至少足够的用于其组合的S层的S层蛋白组合，和（b）异源多肽，（a）的羧基末端或（a）的氨基末端融合，由此呈现在所述细胞的外表面上; 可用作疫苗，用于筛选蛋白质和抗原，并用作固定酶，肽或抗原的支持物。

2. 发明申请

WO2010139728A1 PROCESS AND DEVICE FOR SEPARATING LIQUID FROM A MULTIPHASE MIXTURE 审中-公开
标题翻译：用于从多相混合物中分离液体的方法和装置
公开(公告)号：WO2010139728A1
公开(公告)日：2010-12-09
申请号：PCT/EP2010/057716
申请日：2010-06-02
申请人： SOLVAY SA , DADABHOY, Jal Rustom , FEDELI, Massimo , DHAESE, Patrick, Markus , VAN HOOF, Yvan, Frans
发明人： DADABHOY, Jal Rustom , FEDELI, Massimo , DHAESE, Patrick, Markus , VAN HOOF, Yvan, Frans
IPC分类号： B01J8/00 , B01J8/22 , C01B15/023
CPC分类号： B01J8/228 , B01J8/006 , B01J8/22 , C01B15/023
摘要： Process and device for separating liquid from a multiphase mixture contained in a vessel and comprising solid particles and at least one liquid phase forming together at least one suspension, and a gas phase in which at least part of the mixture is circulated through at least one cross-flow filter located outside the vessel, therefore separating said part of the mixture into a filtered liquid and a concentrate.
摘要翻译：用于从包含在容器中的包含固体颗粒和至少一个在至少一个悬浮液中形成的至少一个液相的气相中分离液体的方法和装置，以及气相，其中至少部分混合物通过至少一个交叉流过滤器位于容器外部，因此将混合物的所述部分分离成过滤液体和浓缩物。

3. 发明申请

WO2010124855A1 CRYOPROTECTANTS FOR FREEZE DRYING OF LACTIC ACID BACTERIA 审中-公开
标题翻译：冻干酸乳杆菌冻干试验
公开(公告)号：WO2010124855A1
公开(公告)日：2010-11-04
申请号：PCT/EP2010/002604
申请日：2010-04-28
申请人： ACTOGENIX NV , CORVELEYN, Sam , DHAESE, Patrick , NEIRYNCK, Sabine , STEIDLER, Lothar
发明人： CORVELEYN, Sam , DHAESE, Patrick , NEIRYNCK, Sabine , STEIDLER, Lothar
IPC分类号： C12N1/04
CPC分类号： A61K35/744 , A23K20/10 , A23L33/10 , A23L33/135 , A23V2002/00 , A23Y2240/41 , A61K47/10 , A61K47/12 , A61K47/36 , C12N1/04 , C12N1/20
摘要： The present invention comprises the discovery and development of an effective cryoprotectant composition, without containing skim milk or any other animal-derived compounds, to achieve long-term stability of freeze-dried lactic acid bacteria (LAB), at different temperatures, whereby the retention of viability of the freeze-dried LAB after 6 months of storage, preferably after 9 months of storage, more preferably after 12 months of storage is more than 50%. The invention is in the field of producing freeze dried bacteria, in particular Lactic acid bacteria. More in particular, the invention relates to the use of a novel combination of cryoprotectants for increasing the viability of bacteria after freeze drying, improving the texture of the lyofilized cake for easy grinding and improving the long term stability of the freeze dried bacteria at different temperature conditions. The invention further relates to such freeze dried bacteria for use in food industry or in human or animal health applications. More in particular, the invention relates to the increased viability and long-term storage of recombinant bacteria capable of expressing heterologous proteins or peptides and administered to humans or animals for therapeutic or vaccination purposes.
摘要翻译：本发明包括在不同温度下发现和开发有效的冷冻保护剂组合物，不含脱脂乳或任何其它动物衍生化合物以达到冷冻干燥的乳酸菌（LAB）的长期稳定性，从而保留冷冻干燥的LAB在储存6个月后的存活率，优选储存9个月后，更优选储存12个月后超过50％。本发明涉及生产冷冻干燥细菌，特别是乳酸菌的领域。更具体地，本发明涉及使用冷冻保护剂的新型组合来增加冷冻干燥后细菌的存活力，改善裂解饼的质地以便于研磨，并提高冷冻干燥细菌在不同温度下的长期稳定性条件。本发明还涉及用于食品工业或人或动物健康应用的这种冷冻干燥细菌。更具体地，本发明涉及能够表达异源蛋白质或肽并且施用于人或动物用于治疗或疫苗接种目的的重组细菌的增加的活力和长期储存。

4. 发明申请

WO1997013847A1 EXPRESSION SYSTEM, VECTOR AND CELL TRANSFORMED THEREBY 审中-公开
标题翻译：表达系统，矢量和电池转换
公开(公告)号：WO1997013847A1
公开(公告)日：1997-04-17
申请号：PCT/BE1996000109
申请日：1996-10-14
申请人： GENENCOR INTERNATIONAL, INC. , CHARMOILLE, Lucien , ANDRE, Christophe , HAZBON, Manzour, Hernando , CORNELIS, Pierre , DHAESE, Patrick
发明人： GENENCOR INTERNATIONAL, INC.
IPC分类号： C12N09/20
CPC分类号： C12N15/78 , C07K14/21 , C11D3/38627 , C12N9/20
摘要： An expression system for producing an enzyme, and a method for preparing same, are disclosed. The system includes a promoter nucleotide sequence, a nucleotide sequence coding for a secretion signal, a nucleotide sequence coding for a mature enzyme and a terminator nucleotide sequence. The expression system is particularly useful for producing a Pseudomonas lipase. Said expression system may be inserted into a vector. A Pseudomonas wisconsinensis strain transformed by the expression vector is used as the host strain. The expression system may also include a nucleotide sequence coding the Pseudomonas wisconsinensis lipase modulator and/or a nucleotide sequence coding for the GPW protein included in the Pseudomonas wisconsinensis lipase operon. The Pseudomonas wisconsinensis lipase modulator that is involved in effective lipase expression and aids the formation of an active lipase is also disclosed. Furthermore, the GPW protein that appears also to be involved in effective lipase expression is disclosed. The resulting lipase may be used in detergent compositions.
摘要翻译：公开了一种用于生产酶的表达系统及其制备方法。该系统包括启动子核苷酸序列，编码分泌信号的核苷酸序列，编码成熟酶的核苷酸序列和终止子核苷酸序列。表达系统对于产生假单胞菌脂肪酶特别有用。所述表达系统可以被插入向量中。将由表达载体转化的威斯康星假单胞菌菌株用作宿主菌株。表达系统还可以包括编码威斯康星州假单胞菌脂肪酶调节剂的核苷酸序列和/或编码威斯康星州假单胞菌脂肪酶操纵子中包含的GPW蛋白的核苷酸序列。还公开了参与有效脂肪酶表达并有助于形成活性脂肪酶的假单胞菌威斯康星州脂肪酶调节剂。此外，还公开了也参与有效脂肪酶表达的GPW蛋白质。所得脂肪酶可用于洗涤剂组合物中。

5. 发明申请

WO9949010A3 PHENOL OXIDIZING ENZYMES AND THEIR USE 审中-公开
标题翻译：苯酚氧化酶及其用途
公开(公告)号：WO9949010A3
公开(公告)日：1999-12-29
申请号：PCT/EP9902042
申请日：1999-03-23
申请人： UNILEVER NV , UNILEVER PLC , CONVENTS DANIEL , AMORY ANTOINE , WANG HUAMING , DHAESE PATRICK , LAMBRECHTS RONGVAUX ANNICK , WANG CYNTHIA
发明人： CONVENTS DANIEL , AMORY ANTOINE , WANG HUAMING , DHAESE PATRICK , LAMBRECHTS-RONGVAUX ANNICK , WANG CYNTHIA
IPC分类号： C11D3/386 , C12N9/02 , C12N15/53
CPC分类号： C12N9/0055 , C11D3/38636 , C12N9/0057 , C12R1/645
摘要： Disclosed herein are phenol oxidizing enzymes obtainable from species of Stachybotrys which are useful in modifying the color associated with dyes and colored compounds, as well as in anti-dye transfer applications. Also disclosed herein are biologically-pure cultures of strains of the genus Stachybotrys, designated herein Stachybotrys parvispora MUCL 38996 and Stachybotrys chartarum MUCL 38898, which are capable of naturally producing the novel phenol oxidizing enzymes. Disclosed herein is the amino acid and nucleic acid sequence for Stachybotrys phenol oxidizing enzymes as well as expression vectors and host cells comprising the nucleic acid. Disclosed herein are methods for producing the phenol oxidizing enzyme as well as methods for constructing expression hosts. Disclosed herein are detergent compositions comprising phenol oxidizing enzymes obtainable from species of Stachybotrys.
摘要翻译：本文公开了可从可用于改变与染料和着色化合物相关的颜色以及抗染料转移应用中的Stachybotrys种获得的酚氧化酶。本文还公开了Stachybotrys菌株的生物纯培养物，本文命名为Stachybotrys parvispora MUCL 38996和Stachybotrys chartarum MUCL 38898，其能够天然产生新型酚氧化酶。本文公开了Stachybotrys苯酚氧化酶的氨基酸和核酸序列以及包含该核酸的表达载体和宿主细胞。本文公开了制备酚氧化酶的方法以及构建表达宿主的方法。本发明公开了包含可从Stachybotrys种获得的酚氧化酶的洗涤剂组合物。

6. 发明申请

WO9519371A3 EXPRESSION OF SURFACE LAYER PROTEINS 审中-公开
标题翻译：表面层蛋白的表达
公开(公告)号：WO9519371A3
公开(公告)日：1995-11-16
申请号：PCT/EP9500147
申请日：1995-01-13
申请人： SOLVAY , DEBLAERE ROLF Y , DESOMER JAN , DHAESE PATRICK
发明人： DEBLAERE ROLF Y , DESOMER JAN , DHAESE PATRICK
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , C07H21/04 , C07K14/235 , C07K14/32 , C07K14/33 , C07K19/00 , C12N1/21 , C12N15/00 , C12N15/12 , C12N15/75 , C12P21/02 , C12R1/07 , A61K301/385 , C12N15/62
CPC分类号： C12N15/75 , A61K38/00 , A61K39/00 , C07K14/32 , C07K2319/00
摘要： A host cell which is provided with an S-layer comprising a fusion polypeptide consisting essentially of: (a) at least sufficient of an S-layer protein for an S-layer composed thereof to assemble, and (b) a heterologous polypeptide which is fused to either the carboxy terminus of (a) or the amino terminus of (a) and which is thereby presented on the outer surface of the said cell; can be used as a vaccine, for screening for proteins and antigens and as a support for immobilizing an enzyme, peptide or antigen.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式