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    • 1. 发明申请
    • METHOD FOR DETERMINING ANAESTHETIC DEPTH
    • 确定神经深度的方法
    • WO1991019453A1
    • 1991-12-26
    • PCT/NL1991000096
    • 1991-06-13
    • STICHTING VOOR DE TECHNISCHE WETENSCHAPPENCLUITMANS, Petrus, Johannes, Maria
    • STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
    • A61B05/0476
    • A61B5/4821A61B5/04845
    • Method for determining the anaesthetic depth of a patient, comprising the repeated administering of sensory stimuli to the patient; the repeated, non-invasive recording of the electrical activity of the patient's brain during a measurement interval following each stimulus; the computation, from a number of measurement intervals, of a representation of the response of a sensory neural pathway to a single stimulus; and the determination of the latencies and amplitudes of maxima and minima in the representation, which are a measure of the anaesthetic depth, wherein the measurement intervals are chosen such that they partially overlap one another. Preferably the length of time between two successive stimuli is a stochastic variable having a negative exponential distribution, the computed representation being the first order kernel.
    • 用于确定患者的麻醉深度的方法,包括向患者反复施用感觉刺激; 在每个刺激之后的测量间隔期间重复地,非侵入性地记录患者脑的电活动; 从多个测量间隔计算感觉神经通路对单个刺激的反应的表示; 以及在表示中确定最大值和最小值的延迟和幅度,其是麻醉剂深度的量度,其中选择测量间隔使得它们彼此部分重叠。 优选地,两个连续刺激之间的时间长度是具有负指数分布的随机变量,所计算的表示是第一阶内核。