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    • 1. 发明申请
    • DISEASE MARKER DETECTION KIT AND DISEASE MARKER DETECTION METHOD
    • 疾病标记检测试剂盒和疾病标记检测方法
    • WO2011162563A3
    • 2012-05-31
    • PCT/KR2011004610
    • 2011-06-24
    • KOREA RES INST OF STANDARDSLEE TAE GEOLCHO YOUNG-LAISON MI YOUNG
    • LEE TAE GEOLCHO YOUNG-LAISON MI YOUNG
    • G01N33/68G01N23/225G01N33/573G01N33/574
    • G01N33/57488G01N33/553G01N33/6848
    • A detection kit according to the present invention is a disease detection kit which is used together with secondary ion mass spectrometry to detect the disease marker contained in a biological sample. The detection kit comprises: a base on which a noble metal film is formed; a reactant which contains a peptide that specifically reacts with the disease marker; first storage means in which the reactant is stored; a sample which contains the biological sample of a possible disease carrier; second storage means in which the sample is stored; mixing means for mixing the reactant and the sample to produce a detection substance which contains the peptide which specifically reacts with the disease marker contained in the biological sample; and contact means for enabling the detection substance produced by the mixing means to contact the base, so as to bind the specifically reacted material to the noble metal film of the base.
    • 根据本发明的检测试剂盒是与二次离子质谱法一起使用以检测生物样品中所含的疾病标志物的疾病检测试剂盒。 检测试剂盒包括:形成有贵金属膜的基材; 含有特异性与疾病标记反应的肽的反应物; 存储反应物的第一储存装置; 包含可能的疾病携带者的生物样品的样品; 存储样品的第二存储装置; 混合装置,用于混合反应物和样品以产生检测物质,其含有与生物样品中所含的疾病标志物特异性反应的肽; 以及用于使得由混合装置产生的检测物质能够接触基底的接触装置,以便将特异反应的材料与基底的贵金属膜结合。