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1. 发明申请

WO2008091113A1 MULTI-STAGE CSTR BIOREACTOR SYSTEM EQUIPPED WITH CELL RECYCLE UNIT 审中-公开
标题翻译：具有细胞回收单元的多级CSTR生物反应器系统
公开(公告)号：WO2008091113A1
公开(公告)日：2008-07-31
申请号：PCT/KR2008/000432
申请日：2008-01-24
申请人： KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY , CHANG, Ho Nam , KIM, Byoungjin , JEONG, Changmoon , KANG, Jong Won , PARK, Joongkon
发明人： CHANG, Ho Nam , KIM, Byoungjin , JEONG, Changmoon , KANG, Jong Won , PARK, Joongkon
IPC分类号： C12M3/00
CPC分类号： C12M27/02 , C12M23/58 , C12M25/18
摘要： The present invention relates to a single CSTR bioreactor equipped with a cell recycle unit, and a multi-stage CSTR bioreactor system in which 2-7 such single CSTR bioreactors are connected in series with each other. According to the present invention, multi-stage fermentation is carried out in the bioreactor equipped with the cell recycle unit, and thus the production of products (alcohols, organic acids, antibiotics, recombinant proteins, etc.) by anaerobic or aerobic microbial fermentation can be increased, and in addition, a final product can be obtained at high concentration, thus improving the productivity and economic efficiency of a microbial process.
摘要翻译：本发明涉及装备有细胞再循环单元的单个CSTR生物反应器和多级CSTR生物反应器系统，其中2-7个这样的单个CSTR生物反应器彼此串联连接。根据本发明，在配备有细胞循环装置的生物反应器中进行多级发酵，因此通过厌氧或需氧微生物发酵生产产物（醇，有机酸，抗生素，重组蛋白等）可以并且另外可以以高浓度获得最终产品，从而提高微生物过程的生产率和经济效率。

2. 发明申请

WO2004069755A1 METHOD FOR PRODUCING A USEFUL COMPOUND AND TREATING A WASTEWATER USING PURE OXYGEN 审中-公开
标题翻译：生产有用化合物的方法和使用纯氧处理废水
公开(公告)号：WO2004069755A1
公开(公告)日：2004-08-19
申请号：PCT/KR2004/000189
申请日：2004-02-03
申请人： E1 BIOTECH CO., LTD , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY , CHANG, Ho Nam , CHANG, Seung Taek , RYU, Chul Hee , SHANG, Longan
发明人： CHANG, Ho Nam , CHANG, Seung Taek , RYU, Chul Hee , SHANG, Longan
IPC分类号： C02F3/26
CPC分类号： C02F3/26 , B01D53/047 , B01D2256/12 , B01D2257/504 , B01D2259/40024 , B01D2259/40032 , B01D2259/40037 , B01D2259/40052 , B01D2259/40062 , B01D2259/40073 , B01D2259/402 , C01B13/0259 , C01B2210/0046 , C01B2210/0051 , C02F3/02 , Y02C10/08 , Y02P20/152 , Y02P30/30 , Y02W10/15
摘要： The present relates to a method of using pure oxygen in microbial fermentation processes and wastewater treatment processes, in which the pure oxygen is produced by a pressure swing adsorption (PSA) process from a gas mixture of air and unused oxygen-containing recycled off-gas from microbial processes which uses oxygen-containing gas in a liquid or gas state. According to the present invention, when pure oxygen with a purity of more than 90% is used in microbial processes, microbial productivity can be about 5 times as increased as it is that in the conventional method using air with an oxygen content of 21%, and the volume of an active sludge tank in wastewater treatment processes can be reduced to at most 1/5 of the volume as compared to the conventional method. Also, the off-gas from such pure oxygen processes has a high oxygen content of about 70-80%. Thus, when the off-gas is recycled with air for the supplement of oxygen consumption, the gas mixture with an oxygen content of about 40% is used as feed gas for the PSA process, and CO 2 generated by microbial breathing is also removed. Thus, in the present invention, the volume of a PSA column and an air compressor for supplying the feed gas can be reduced to less than ½ of the volume as compared to that of the use of air.
摘要翻译：本发明涉及在微生物发酵过程和废水处理过程中使用纯氧的方法，其中通过来自空气和未使用的含氧再循环废气的混合气体的变压吸附（PSA）方法产生纯氧来自使用含有液体或气体状态的含氧气体的微生物过程。根据本发明，当在微生物过程中使用纯度大于90％的纯氧时，微生物生产率可以是使用含氧量为21％的空气的常规方法的5倍，与传统方法相比，废水处理过程中活性污泥槽的体积可以降低到体积的至多1/5。此外，来自这种纯氧方法的废气具有约70-80％的高氧含量。因此，当用空气再循环废气以补充氧气消耗时，氧气含量为约40％的气体混合物用作PSA过程的进料气体，并且还除去由微生物呼吸产生的CO 2。因此，在本发明中，与使用空气相比，用于供给进料气体的PSA柱和空气压缩机的体积可以减小到小于体积的1/2。

3. 发明申请

WO0200846A9 ORGANIC ACID PRODUCING MICROORGANISM AND PROCESS FOR PREPARING ORGANIC ACIDS EMPLOYING THE SAME 审中-公开
标题翻译：有机酸生产微生物和制备使用相同有机酸的方法
公开(公告)号：WO0200846A9
公开(公告)日：2002-03-14
申请号：PCT/KR0101127
申请日：2001-06-29
申请人： BIOINFORMATIX INC , LEE SANG YUP , CHANG HO NAM , LEE PYUNG CHEON , LEE WOO GI
发明人： LEE SANG-YUP , CHANG HO-NAM , LEE PYUNG-CHEON , LEE WOO-GI
IPC分类号： C12N1/20 , C12P7/46 , C12P7/54 , C12P7/56
CPC分类号： C12P7/56 , C12P7/46 , C12P7/54
摘要： A novel microorganism capable of producing organic acids, Mannheimia sp. 55E, and a process for producing organic acid through anaerobic and aerobic incubation using the novel microorganism are provided. The method of producing an organic acid using the microorganism involves incubating Mannheimia sp. 55E with Accession Number KCTC 0769BP in a medium under anaerobic or aerobic conditions and obtaining an organic acid from the medium. Mannheimia sp. 55E produces succinic acid, lactic acid, and formic acid under anaerobic conditions saturated with CO2, and succinic acid, lactic acid, acetic acid, and formic acid under aerobic or N2 anaerobic conditions. Mannheimia sp. 55E is a facultative anaerobe tolerant of oxygen. Thus, the use of Mannheimia sp. 55E in producing organic acids can eliminate a problem of process instability, which would occur by the presence of oxygen in a fermentation process of producing organic acids using an obligate anaerobic microorganism.
摘要翻译：一种能够产生有机酸的新型微生物曼海姆藻（Mannheimia sp。） 55E，以及使用该新型微生物通过厌氧和有氧培养生产有机酸的方法。使用微生物生产有机酸的方法涉及培养曼海姆藻。 55E，编号为KCTC 0769BP，在厌氧或好氧条件下培养，并从培养基中获得有机酸。曼海姆藻 55E在厌氧条件下用CO 2饱和，在需氧或N 2厌氧条件下生产琥珀酸，乳酸，甲酸和琥珀酸，乳酸，乙酸和甲酸。曼海姆藻 55E是耐氧兼性厌氧菌。因此，使用Mannheimia sp。 55E在生产有机酸中可以消除工艺不稳定性的问题，这可能由于在使用专性厌氧微生物生产有机酸的发酵工艺中存在氧气而发生。

4. 发明申请

WO2003024632A1 ON-SITE TREATMENT METHOD OF FOOD WASTE GENERATED FROM COLLECTIVE RESIDENCE OR INSTITUTIONAL FOOD SERVICE FACILITIES 审中-公开
标题翻译：从集体居住或机构性食品服务设施产生的食品废物的现场处理方法
公开(公告)号：WO2003024632A1
公开(公告)日：2003-03-27
申请号：PCT/KR2002/001628
申请日：2002-08-29
申请人： E1 BIOTECH CO., LTD , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY , CHANG, Ho-Nam , KIM, Do-Yun , KIM, Moon-Il , RYU, Chul-Hee , LEE, Woo-Gi
发明人： CHANG, Ho-Nam , KIM, Do-Yun , KIM, Moon-Il , RYU, Chul-Hee , LEE, Woo-Gi
IPC分类号： B09B3/00
CPC分类号： B09B3/00 , C05F9/00 , Y02A40/214 , Y02W30/47 , Y10S210/92 , C05F9/02 , C05F9/04
摘要： Disclosed is an on-site treatment method of food waste generated from multi-unit dwelling and institutional food service facilities, by transporting wastewater-containing food waste to a separation chamber by use of domestic wastewater or an additional transporter; separating the transported food waste to wastewater and food waste; and treating the separated wastewater in a sewage disposal plant, and the separated food waste using disposal equipment. Such food waste can be treated even using disposal equipment of small capacities, due to separation of wastewater and food waste, ocmpared to disposal equipment of large capacities required for treating wastewater and food waste together. Also, the quality of the separated wastewater is better than the conventional quality of wastewater, and thus loads of the sewage disposal plant can be efficiently decreased.
摘要翻译：披露了从多单位住宅和机构食品服务设施产生的食品废物的现场处理方法，将含有废水的食物废物运送到分离室，使用生活废水或附加运输工具; 将运送的食物废物分解成废水和食物废物; 并处理污水处理厂中分离的废水，以及使用处置设备分离的食物废物。由于废水和食物废物分离，处理废水和食物废物所需的大容量处理设备，可以使用小容量的处理设备来处理这种食物废物。此外，分离废水的质量优于常规废水质量，因此可以有效降低污水处理厂的负荷。

5. 发明申请

WO2011084002A3 METHOD FOR PRODUCING ORGANIC ACIDS FROM BIOMASS 审中-公开
标题翻译：从生物量生产有机酸的方法
公开(公告)号：WO2011084002A3
公开(公告)日：2012-01-12
申请号：PCT/KR2011000103
申请日：2011-01-07
申请人： KOREA ADVANCED INST SCI & TECH , CHANG HO NAM , LEE SANG YUP , YANG SEUNG MAN , KIM NAG JONG , KANG JONG WON , JEONG CHANGMOON , CHOI JIN DAL RAE
发明人： CHANG HO NAM , LEE SANG YUP , YANG SEUNG MAN , KIM NAG JONG , KANG JONG WON , JEONG CHANGMOON , CHOI JIN DAL RAE
IPC分类号： C12P7/04 , B09B3/00
CPC分类号： C12P7/6409 , C12P7/40
摘要： The present invention relates to a method for producing organic acids from biomass, and more specifically relates to a method for producing various organic acids (volatile fatty acids) from land-based, freshwater-based, marine or biodegradable organic mixed biomass by using a high-density cell culture method, and then concentrating and distilling the same. The method for producing organic acids from biomass comprises the steps of: (a) producing organic acids by fermenting biomass; (b) concentrating the organic acids so produced by at least 30%; and (c) recovering the organic acids by fractional distillation of the concentrated organic acid. A method for isolating organic acids produced economically from biomass according to the present invention can be used to advantage in converting organic acids into fuel or compounds such as alcohols, esters and alkanes in addition to the economic use of organic acids.
摘要翻译：本发明涉及从生物质生产有机酸的方法，更具体地涉及一种通过使用高的从陆基，淡水，海洋或可生物降解的有机混合生物质生产各种有机酸（挥发性脂肪酸）的方法浓缩细胞培养法，然后浓缩蒸馏。从生物质生产有机酸的方法包括以下步骤：（a）通过发酵生物质生产有机酸; （b）将如此生产的有机酸浓缩至少30％; 和（c）通过浓缩有机酸的分馏回收有机酸。根据本发明的从生物质经济地分离有机酸的方法除了经济地使用有机酸之外，还可用于将有机酸转化成燃料或化合物如醇，酯和烷烃。

6. 发明申请

WO2011084002A2 METHOD FOR PRODUCING ORGANIC ACIDS FROM BIOMASS 审中-公开
标题翻译：从生物量生产有机酸的方法
公开(公告)号：WO2011084002A2
公开(公告)日：2011-07-14
申请号：PCT/KR2011000103
申请日：2011-01-07
申请人： KOREA ADVANCED INST SCI & TECH , CHANG HO NAM , LEE SANG YUP , YANG SEUNG MAN , KIM NAG JONG , KANG JONG WON , JEONG CHANGMOON , CHOI JIN DAL RAE
发明人： CHANG HO NAM , LEE SANG YUP , YANG SEUNG MAN , KIM NAG JONG , KANG JONG WON , JEONG CHANGMOON , CHOI JIN DAL RAE
IPC分类号： C12P7/04 , B09B3/00
CPC分类号： C12P7/6409 , C12P7/40
摘要： The present invention relates to a method for producing organic acids from biomass, and more specifically relates to a method for producing various organic acids (volatile fatty acids) from land-based, freshwater-based, marine or biodegradable organic mixed biomass by using a high-density cell culture method, and then concentrating and distilling the same. The method for producing organic acids from biomass comprises the steps of: (a) producing organic acids by fermenting biomass; (b) concentrating the organic acids so produced by at least 30%; and (c) recovering the organic acids by fractional distillation of the concentrated organic acid. A method for isolating organic acids produced economically from biomass according to the present invention can be used to advantage in converting organic acids into fuel or compounds such as alcohols, esters and alkanes in addition to the economic use of organic acids.
摘要翻译：本发明涉及从生物质生产有机酸的方法，更具体地涉及一种通过使用高的从陆基，淡水，海洋或可生物降解的有机混合生物质生产各种有机酸（挥发性脂肪酸）的方法浓缩细胞培养法，然后浓缩蒸馏。从生物质生产有机酸的方法包括以下步骤：（a）通过发酵生物质生产有机酸; （b）将如此生产的有机酸浓缩至少30％; 和（c）通过浓缩有机酸的分馏回收有机酸。根据本发明的从生物质经济地分离有机酸的方法除了经济地使用有机酸之外，还可用于将有机酸转化成燃料或化合物如醇，酯和烷烃。

7. 发明申请

WO2004058424A1 ON-SITE TREATMENT METHOD OF GROUND FOOD WASTES 审中-公开
标题翻译：地面食物垃圾的现场处理方法
公开(公告)号：WO2004058424A1
公开(公告)日：2004-07-15
申请号：PCT/KR2003/002881
申请日：2003-12-30
申请人： E1 BIOTECH CO., LTD , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY , CHANG, Ho Nam , CHANG, Seung Teak
发明人： CHANG, Ho Nam , CHANG, Seung Teak
IPC分类号： B09B5/00
CPC分类号： E03F5/14 , B01D21/0012 , B09B3/00 , E03C1/266 , E03C2201/40 , Y02E50/343 , Y02W30/20
摘要： The present invention relates to a method for the on-site treatment of food wastes from group residential facilities, such as apartment buildings and tenement houses, group kitchen facilities, such as restaurants, and homes, in which the food wastes are ground by a disposer in a generation site, such as a kitchen, and then transferred using kitchen water. Before or after such a transfer, the food wastes are separated from kitchen water and treated on-site. The food waste treatment method of the present invention is significantly different from the commonly used method in which the food wastes are collected from the generation site, and then incinerated, buried in a landfill, or recycled as feedstuff or compost. The inventive method is a treatment system considering more convenient and sanitary aspects than any method in both inside and outside of Korea by allowing the food wastes to be treated in a small space within the generation site, thereby providing a method of fundamentally solving the problem of food wastes generated in large cities.
摘要翻译：本发明涉及一种用于从诸如公寓楼和物业单位等小组住宅设施，餐馆和家庭的小组厨房设施，食物垃圾由处理者研磨的食品废物的现场处理方法在一个一代的场所，如厨房，然后用厨房水转移。在这种转移之前或之后，食物废物与厨房水分离并在现场进行处理。本发明的食物废物处理方法与从生成现场收集食品废弃物然后焚烧，埋在垃圾填埋场中或作为饲料或堆肥再循环的常用方法显着不同。本发明的方法是通过允许食物废物在生殖现场内的小空间中进行处理，考虑比韩国内外任何方法更方便和卫生的处理系统，从而提供一种从根本上解决问题的方法大城市产生的食物废物。

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