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1. 发明申请

WO2008023048A2 METHOD OF COATING MEDICAL DEVICES 审中-公开
标题翻译：涂敷医疗器械的方法
公开(公告)号：WO2008023048A2
公开(公告)日：2008-02-28
申请号：PCT/EP2007/058777
申请日：2007-08-23
申请人： SAUFLON CL LIMITED , SURFACE INNOVATIONS LIMITED , BROAD, Robert Andrew , BADYAL, Jas Pal Singh
发明人： BROAD, Robert Andrew , BADYAL, Jas Pal Singh
IPC分类号： B29D11/00 , B05D7/24
CPC分类号： B29D11/00038 , B29D11/00865
摘要： A method of coating a contact lens comprising the steps of forming an initiator layer on the surface of the contact lens by plasma deposition of at least one initiator monomer and polymerising a propagation monomer onto the initiator layer to form a coating layer of a polymeric material on the contact lens and a method of coating a medical device comprising the steps of forming an initiator polymer layer on at least a part of the medical device by plasma deposition of at least one initiator monomer and polymerising at least one zwitterionic monomer onto the initiator layer to form a coating layer of a polymeric material on the medical device.
摘要翻译：一种涂覆隐形眼镜的方法，包括以下步骤：通过至少一种引发剂单体的等离子体沉积在接触透镜的表面上形成引发剂层，并将传播单体聚合到引发剂层上以形成聚合物材料的涂层所述隐形眼镜和涂覆医疗装置的方法包括以下步骤：通过至少一种引发剂单体的等离子体沉积和将至少一种两性离子单体聚合到所述引发剂层上而在所述医疗装置的至少一部分上形成引发剂聚合物层，在医疗装置上形成聚合材料的涂层。

2. 发明申请

WO2008061992A2 CONTACT LENS 审中-公开
标题翻译：隐形眼镜
公开(公告)号：WO2008061992A2
公开(公告)日：2008-05-29
申请号：PCT/EP2007/062592
申请日：2007-11-20
申请人： SAUFLON CL LIMITED , BROAD, Robert Andrew
发明人： BROAD, Robert Andrew
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08F283/12 , C08F290/068 , C08L43/04 , C08L51/085
摘要： A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C 1-4 alkyl, and each b independently is C 1-4 alkyl; B) at least 10 weight percent, based on the total composition weight excluding solvent, of 3-methacryloxypropyl tris(trimethylsiloxy) silane; C) N-vinyl pyrrolidone; and D) at least one other non-ionic hydrophilic monomer wherein the combined amount of A) and B) is at least 20 weight percent based on the total composition weight excluding solvent, and wherein the N-vinyl pyrrolidone (NVP) is present in such an amount that the reaction product comprises polyvinyl pyrrolidone (PVP) homopolymer.
摘要翻译：一种由包含以下物质组成的组合物形成的隐形眼镜：A）至少一种含有机硅的单体，其中n为1至3，所述反应产物为基于不包括溶剂在内的总组合物重量计至少10重量％ m为9〜15，各自独立地为C 1-4烷基，各b独立地为C 1-4烷基; B）基于不包括溶剂的总组合重量的至少10重量％的3-甲基丙烯酰氧基丙基三（三甲基甲硅烷氧基）硅烷; C）N-乙烯基吡咯烷酮; 和D）至少一种其它非离子亲水性单体，其中基于不包括溶剂的总组合物重量，A）和B）的组合量为至少20重量％，并且其中N-乙烯基吡咯烷酮（NVP）存在于反应产物包含聚乙烯吡咯烷酮（PVP）均聚物的量。

3. 发明申请

WO2004076160A1 CONTACT LENS MOULD 审中-公开
标题翻译：联系镜头模具
公开(公告)号：WO2004076160A1
公开(公告)日：2004-09-10
申请号：PCT/GB2004/000514
申请日：2004-02-09
申请人： CONCAVEX LTD , BROAD, Robert, Andrew , MCEVOY, Steven, John , MACCABEE, Gordon, Frederick , DUNCAN, Alan
发明人： BROAD, Robert, Andrew , MCEVOY, Steven, John , MACCABEE, Gordon, Frederick , DUNCAN, Alan
IPC分类号： B29D11/00
CPC分类号： B29C33/0055 , B29C33/0038 , B29D11/00057 , B29L2011/0041
摘要： The present invention discloses a contact lens mould for producing a contact lens. The mould comprises a first mould half (10) having a convex moulding surface (36m) of predetermined curvature, and a second mould half (12) having a concave moulding surface (26f) of predetermined curvature. The first mould half (10) is provided with an annular abutment surface (38m) which circumferentially surrounds and is contiguous with the convex moulding surface (36m), and the second mould half (12) is provided with a flexible annular lip (28f) which circumferentially surrounds the concave moulding surface (26f). In use, when the mould halves (10, 12) are brought together, the annular lip (28f) forms a continuous line contact with the abutment surface (38m) whereby a mould cavity (40) is defined between the moulding surfaces (26f, 36m), a radially inner surface (42f) of the annular lip (28f) and at least part of the abutment surface (38m), and an angle (α) of less than 180° is defined between the abutment surface (38m) and the convex moulding surface (36m) at their intersection and an included angle (θ) of less than 90° is defined between the abutment surface (38m) and the radially inner surface (42f) of the lip (28f). As the mould halves (10, 12) are brought closer together during polymerisation, the lip (28f) flexes radially outwardly.
摘要翻译：本发明公开了一种用于制造隐形眼镜的隐形眼镜模具。模具包括具有预定曲率的凸形成型表面（36m）的第一半模（10）和具有预定曲率的凹形成型表面（26f）的第二半模（12）。第一半模（10）设置有环形邻接表面（38m），环形邻接表面（38m）周向地围绕并与凸模制表面（36m）邻接，并且第二半模（12）设置有柔性环形唇缘（28f）其周向地围绕凹形模制表面（26f）。在使用中，当半模（10,12）被集合在一起时，环形唇缘（28f）与邻接表面（38m）形成连续的线接触，从而在模制表面（26f， 36m），所述环形唇缘（28f）的径向内表面（42f）和所述邻接表面（38m）的至少一部分以及小于180°的角度（α）被限定在所述邻接表面（38m）和在邻接表面（38m）和唇缘（28f）的径向内表面（42f）之间限定了其相交处的凸形成型表面（36m）和小于90°的夹角（theta）。当半聚合物（10,12）在聚合期间更靠近在一起时，唇缘（28f）径向向外弯曲。

4. 发明申请

WO2011045299A9 METHOD OF MAKING A CONTACT LENS 审中-公开
公开(公告)号：WO2011045299A9
公开(公告)日：2011-04-21
申请号：PCT/EP2010/065248
申请日：2010-10-12
申请人： SAUFLON CL LIMITED , BROAD, Robert, Andrew , GIBSON, Ian
发明人： BROAD, Robert, Andrew , GIBSON, Ian
IPC分类号： G02B1/04
摘要： A method of making a contact lens comprising the steps of reacting in a mould a polymerisable formulation comprising at least one fluorine-containing silicone monomer at least one non-fluorine-containing silicone monomer and at least one hydrophilic monomer to form a contact lens, subjecting the contact lens to one or more solvent extraction steps to remove impurities, oligomers and unreacted monomers and hydrate the contact lens, wherein all of the solvent extraction steps are undertaken using an aqueous solvent.

5. 发明申请

WO2008061992A3 CONTACT LENS 审中-公开
标题翻译：隐形眼镜
公开(公告)号：WO2008061992A3
公开(公告)日：2008-07-17
申请号：PCT/EP2007062592
申请日：2007-11-20
申请人： SAUFLON CL LTD , BROAD ROBERT ANDREW
发明人： BROAD ROBERT ANDREW
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08F283/12 , C08F290/068 , C08L43/04 , C08L51/085
摘要： A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C 1-4 alkyl, and each b independently is C 1-4 alkyl; B) at least 10 weight percent, based on the total composition weight excluding solvent, of 3-methacryloxypropyl tris(trimethylsiloxy) silane; C) N-vinyl pyrrolidone; and D) at least one other non-ionic hydrophilic monomer wherein the combined amount of A) and B) is at least 20 weight percent based on the total composition weight excluding solvent, and wherein the N-vinyl pyrrolidone (NVP) is present in such an amount that the reaction product comprises polyvinyl pyrrolidone (PVP) homopolymer.
摘要翻译：由包含如下反应产物的组合物形成的隐形眼镜：A）基于除溶剂之外的总组合物重量，至少10重量％的至少一种式I的含硅氧烷单体：其中n为1至3 m为9至15，各自独立地为C 1-4烷基，并且每个b独立地为C 1-4烷基; B）基于不包括溶剂的总组合物重量，至少10重量％的3-甲基丙烯酰氧基丙基三（三甲基甲硅烷氧基）硅烷; C）N-乙烯基吡咯烷酮; 和D）至少一种其他非离子型亲水性单体，其中基于不包括溶剂的总组合物重量，A）和B）的组合量为至少20重量％，并且其中N-乙烯基吡咯烷酮（NVP）存在于反应产物包含聚乙烯吡咯烷酮（PVP）均聚物的量。

6. 发明申请

WO2011045299A1 METHOD OF MAKING A CONTACT LENS 审中-公开
标题翻译：制造接触镜的方法
公开(公告)号：WO2011045299A1
公开(公告)日：2011-04-21
申请号：PCT/EP2010065248
申请日：2010-10-12
申请人： SAUFLON CL LTD , BROAD ROBERT ANDREW , GIBSON IAN
发明人： BROAD ROBERT ANDREW , GIBSON IAN
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08F220/56 , C08F226/10 , C08F230/08 , C08G77/20 , C08G77/24 , G02C7/04 , C08L83/10 , C08L43/04
摘要： A method of making a contact lens comprising the steps of reacting in a mould a polymerisable formulation comprising at least one fluorine-containing silicone monomer at least one non-fluorine-containing silicone monomer and at least one hydrophilic monomer to form a contact lens, subjecting the contact lens to one or more solvent extraction steps to remove impurities, oligomers and unreacted monomers and hydrate the contact lens, wherein all of the solvent extraction steps are undertaken using an aqueous solvent.
摘要翻译：一种制造隐形眼镜的方法，包括以下步骤：在模具中使包含至少一种含氟硅氧烷单体的至少一种含氟硅氧烷单体和至少一种亲水性单体的可聚合制剂反应以形成隐形眼镜，将隐形眼镜转移到一个或多个溶剂萃取步骤以去除杂质，低聚物和未反应的单体并水合隐形眼镜，其中所有溶剂萃取步骤都是使用水性溶剂进行的。

7. 发明申请

WO2008023048A3 METHOD OF COATING A CONTACT LENS 审中-公开
标题翻译：涂层接触镜的方法
公开(公告)号：WO2008023048A3
公开(公告)日：2008-05-08
申请号：PCT/EP2007058777
申请日：2007-08-23
申请人： SAUFLON CL LTD , SURFACE INNOVATIONS LTD , BROAD ROBERT ANDREW , BADYAL JAS PAL SINGH
发明人： BROAD ROBERT ANDREW , BADYAL JAS PAL SINGH
IPC分类号： B29D11/00 , B05D7/24
CPC分类号： B29D11/00038 , B29D11/00865
摘要： A method of coating a contact lens comprising the steps of forming an initiator layer on the surface of the contact lens by plasma deposition of at least one initiator monomer and polymerising a propagation monomer onto the initiator layer to form a coating layer of a polymeric material on the contact lens and a method of coating a medical device comprising the steps of forming an initiator polymer layer on at least a part of the medical device by plasma deposition of at least one initiator monomer and polymerising at least one zwitterionic monomer onto the initiator layer to form a coating layer of a polymeric material on the medical device.
摘要翻译：一种涂覆隐形眼镜的方法，包括以下步骤：通过至少一种引发剂单体的等离子体沉积在接触透镜的表面上形成引发剂层，并将传播单体聚合到引发剂层上以形成聚合物材料的涂层所述隐形眼镜和涂覆医疗装置的方法包括以下步骤：通过至少一种引发剂单体的等离子体沉积和将至少一种两性离子单体聚合到所述引发剂层上而在所述医疗装置的至少一部分上形成引发剂聚合物层，在医疗装置上形成聚合材料的涂层。

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