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1. 发明申请

WO2018146689A1 TELOMERASE ACTIVATING COMPOUNDS FOR USE IN FERTILITY AND RELATED APPLICATIONS 审中-公开
公开(公告)号：WO2018146689A1
公开(公告)日：2018-08-16
申请号：PCT/IL2018/050161
申请日：2018-02-12
申请人： BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
发明人： PRIEL, Esther
IPC分类号： A61K31/05 , A61K31/055 , A61K31/09 , A61K31/137 , A61K31/4025 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/66 , A61K45/06 , A61P15/00 , A61P15/08 , A61P35/00 , A61P43/00
摘要： The present invention is directed to methods and uses of a series of compounds and compositions comprising the same for treating diseases, disorders and/or conditions related to fertility and preserving same and conditions related to same. In some aspects, the compounds and or compositions as herein described promote, improve, recover or restore fertility in a subject in need thereof, including in male and/or female subjects. Such methods/uses include promoting, enhancing or improving fertility-associated cell or tissue yield as part of an in vitro fertilization protocol.

2. 发明申请

WO2014045274A1 BILAYER GRAPHENE DIODE 审中-公开
标题翻译： BILAYER石墨二极管
公开(公告)号：WO2014045274A1
公开(公告)日：2014-03-27
申请号：PCT/IL2013/050763
申请日：2013-09-10
申请人： BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
发明人： GOLAN, Erez , GERSHANIK, Arcady
IPC分类号： H01L51/05 , H01L29/12 , H01L29/861
CPC分类号： H01L29/861 , H01L29/1606 , H01L51/0075 , H01L51/0575
摘要： The invention is aimed at bilayer graphene diodes and methods thereof. A bilayer graphene diode according to the invention includes an insulating substrate, a bilayer graphene layer on the insulating substrate, a source electrode in contact with the bilayer graphene layer, a drain electrode in contact with the bilayer graphene layer, an insulating layer on the bilayer graphene layer, and a first self-assembled monolayer (SAM) layer on the insulating layer. Some embodiments include a second SAM layer in a recess in the insulating substrate under the bilayer graphene layer.
摘要翻译：本发明涉及双层石墨烯二极管及其方法。根据本发明的双层石墨烯二极管包括绝缘基板，绝缘基板上的双层石墨烯层，与双层石墨烯层接触的源电极，与双层石墨烯层接触的漏电极，双层上的绝缘层石墨烯层和绝缘层上的第一自组装单层（SAM）层。一些实施例包括位于双层石墨烯层下面的绝缘衬底的凹部中的第二SAM层。

3. 发明申请

WO2014041536A1 INTEGRATED CIRCUIT WITH PHOTONIC ELEMENTS 审中-公开
标题翻译：集成电路与光电元件
公开(公告)号：WO2014041536A1
公开(公告)日：2014-03-20
申请号：PCT/IL2013/050765
申请日：2013-09-11
申请人： BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , BAR-ILAN UNIVERSITY
发明人： FISH, Alexander , ZALEVSKY, Zeev , MEIRI, Amihai , BASS, Ori
IPC分类号： G02B6/12 , G02B6/42 , G02F1/377 , G02F3/02 , H01L31/12
CPC分类号： G02B6/1225 , B82Y20/00 , G02B6/12004 , G02B6/12007 , G02B6/122 , G06E3/005
摘要： An integrated circuit with electronic and photonic elements includes: at least one electronic processing layer; at least one interconnect layer adjacent to said electronic processing layer, and at least one photonic element located within a respective interconnect layer. The photonic elements implement respective operations upon optical signals. At least a portion of each interconnect layer which includes photonic elements is optically-conductive, and therefore suitable for the inclusion of the photonic elements. In some embodiments said photonic elements comprising optical waveguides are configured as optical logic gates to perform logic operations.
摘要翻译：具有电子和光子元件的集成电路包括：至少一个电子处理层; 与所述电子处理层相邻的至少一个互连层以及位于相应互连层内的至少一个光子元件。光子元件根据光信号实现各自的操作。包括光子元件的每个互连层的至少一部分是光学导电的，因此适合于包含光子元件。在一些实施例中，包括光波导的所述光子元件被配置为执行逻辑运算的光逻辑门。

4. 发明申请

WO2013001538A1 FLEXIBLE BLADE RHEOMETER 审中-公开
标题翻译：柔性叶片温度计
公开(公告)号：WO2013001538A1
公开(公告)日：2013-01-03
申请号：PCT/IL2012/050225
申请日：2012-06-28
申请人： RAMOT AT TEL-AVIV UNIVERSITY LTD. , BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , LIBERZON, Alexander , GURKA, Roi
发明人： LIBERZON, Alexander , GURKA, Roi
IPC分类号： G01N11/10
CPC分类号： G01N11/14 , G01N11/10
摘要： A rheometer including a flexible blade, a unit for measuring flex of at least part of the blade, a computation unit configured for converting input of parameters from the measurement unit to output of viscosity measurement. A method for determining viscosity including rotating a flexible blade in a medium whose viscosity is being measured, measuring blade flex of at least part of the blade, converting the blade flex measurement to a viscosity measurement, and producing output of determined viscosity. Related apparatus and methods are also described.
摘要翻译：一种流变仪，包括柔性叶片，用于测量叶片的至少一部分的挠曲的单元，被配置为将来自测量单元的参数的输入转换为粘度测量的输出的计算单元。一种用于确定粘度的方法，包括在其测量粘度的介质中旋转柔性叶片，测量至少部分叶片的叶片挠曲，将叶片挠曲测量值转换为粘度测量值，并产生确定的粘度的输出。还描述了相关装置和方法。

5. 发明申请

WO2012070054A1 METHOD AND SYSTEM FOR ELECTRON RADIOTHERAPY 审中-公开
标题翻译：电子放射治疗方法与系统
公开(公告)号：WO2012070054A1
公开(公告)日：2012-05-31
申请号：PCT/IL2011/050033
申请日：2011-11-28
申请人： TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. , BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , ALEZRA, Dror , NARDI, Eran , KOREN, Sion , ORION, Itzhak
发明人： ALEZRA, Dror , NARDI, Eran , KOREN, Sion , ORION, Itzhak
IPC分类号： A61N5/10
CPC分类号： G21K1/093 , A61B5/05 , A61N5/1042 , A61N5/1043 , A61N2005/1089
摘要： A radiotherapy system is disclosed. The radiotherapy system comprises an electron beam generator for generating an electron beam and a magnetic field generator for generating a magnetic field. In some embodiments of the present invention, the system further comprises a controller for controlling the electron beam and the magnetic field generators such that the electron beam is dynamically shifted and the magnetic field is dynamically redirected synchronously with the shifting.
摘要翻译：公开了放射治疗系统。放射治疗系统包括用于产生电子束的电子束发生器和用于产生磁场的磁场发生器。在本发明的一些实施例中，系统还包括用于控制电子束和磁场发生器的控制器，使得电子束被动态地移位，并且磁场与移位同步地被动态地重定向。

6. 发明申请

WO2011128895A2 SULFOTRANSFERASE OF A RED MICROALGA AND USES THEREOF 审中-公开
标题翻译：红色微藻的红色荧光蛋白及其用途
公开(公告)号：WO2011128895A2
公开(公告)日：2011-10-20
申请号：PCT/IL2011/000299
申请日：2011-04-11
申请人： BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , ARAD, Shoshana , PLESSER, Lena , WEINSTEIN, Yaakov
发明人： ARAD, Shoshana , PLESSER, Lena , WEINSTEIN, Yaakov
IPC分类号： A01H5/00
CPC分类号： C12N9/13 , C07K14/405 , C12N9/10 , C12N15/8243 , C12P11/00 , C12P19/04 , Y02P20/52
摘要： An isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel sulfotransferase is provided together with a composition which includes the isolated protein. A transgenic organism transformed by a polynucleotide encoding a protein which is at least partially encoded by a novel sulfotransferase is also provided. The invention also includes a process for in-vivo and in-vitro making a sulfated polysaccharide from an unsulfated polysaccharide or increasing the sulfur content of an already sulfated polysaccharide.
摘要翻译：与编码新型磺基转移酶的多核苷酸序列至少部分编码的分离的蛋白质与包含分离的蛋白质的组合物一起提供。还提供了由编码至少部分由新型磺基转移酶编码的蛋白质的多核苷酸转化的转基因生物体。本发明还包括用于体内和体外制备来自未硫酸化多糖的硫酸化多糖或增加已硫酸化多糖的硫含量的方法。

7. 发明申请

WO2011111052A1 PROCESS FOR THE PREPARATION OF HETEROGENEOUS FENTON CATALYTIC FILTER 审中-公开
标题翻译：异构FENTON催化过滤器的制备方法
公开(公告)号：WO2011111052A1
公开(公告)日：2011-09-15
申请号：PCT/IL2011/000240
申请日：2011-03-10
申请人： BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , LANDAU, Miron , HERSKOWITZ, Mordechai , SATISHKUMAR, Geonker
发明人： LANDAU, Miron , HERSKOWITZ, Mordechai , SATISHKUMAR, Geonker
IPC分类号： B01J23/745 , B01J23/83 , B01J35/00 , B01J37/02 , B01J37/04 , C02F1/00
CPC分类号： B01J23/745 , B01J21/08 , B01J23/002 , B01J23/83 , B01J35/0006 , B01J35/002 , B01J37/0201 , B01J37/0209 , B01J37/04 , B01J37/06 , C02F1/66 , C02F1/722 , C02F1/725 , C02F2101/345 , C02F2209/06 , C02F2305/026
摘要： The invention provides a process for the preparation of an iron-containing catalyst suitable for use in Fenton oxidation reactions, comprising preparing a mixture of a source of iron ions and solid support particles, said support particles having chemically reactive groups present on their surface, contacting said mixture with an acidic liquid medium thereby causing the release of iron ions from said iron source to form a catalyst comprising said solid support particles and said iron ions located on the surface of said support particles. The invention also provides the catalyst and a method for using the catalyst in purifying wastewater.
摘要翻译：本发明提供了一种制备适用于芬顿氧化反应的含铁催化剂的方法，包括制备铁离子源和固体载体颗粒的混合物，所述载体颗粒在其表面上存在化学反应基团，所述混合物具有酸性液体介质，从而导致从所述铁源释放铁离子以形成包含位于所述载体颗粒表面上的所述固体支持颗粒和所述铁离子的催化剂。本发明还提供催化剂和使用催化剂净化废水的方法。

8. 发明申请

WO2011104708A3 METHODS FOR INHIBITING NECROSIS 审中-公开
标题翻译：禁忌症的方法
公开(公告)号：WO2011104708A3
公开(公告)日：2011-09-01
申请号：PCT/IL2011/000182
申请日：2011-02-23
申请人： BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , PAROLA, Abraham , NATHAN, Ilana , KASHER, Ron , LERNER YARDENI, Jenny , COHEN, Aviv
发明人： PAROLA, Abraham , NATHAN, Ilana , KASHER, Ron , LERNER YARDENI, Jenny , COHEN, Aviv
IPC分类号： A61K38/00
摘要： A method of treating a patient suffering from a disease characterized by tissue necrosis by administering to the patient a necrosis inhibitor and/or a Humanin or a derivative of Humanin is provided. The invention further includes a method for prophylactically treating a patient at risk for a pathological condition that is precipitated at least in part by tissue necrosis by administering to the patient a necrosis inhibitor and/or a Humanin or a derivative of Humanin.
摘要翻译：通过向患者施用坏死抑制剂和/或护脑素或护脑素衍生物来治疗患有以组织坏死为特征的疾病的患者的方法。本发明进一步包括通过向患者施用坏死抑制剂和/或护脑素或护脑素衍生物来预防性治疗处于至少部分由组织坏死沉淀的病理性病症风险中的患者的方法。

9. 发明申请

WO2010128513A3 A METHOD AND APPARATUS FOR HIGH PRECISION SPECTROSCOPY 审中-公开
标题翻译：高精度光谱学的方法和设备
公开(公告)号：WO2010128513A3
公开(公告)日：2010-11-11
申请号：PCT/IL2010/000369
申请日：2010-05-06
申请人： BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , GROSWASSER, David
发明人： GROSWASSER, David
IPC分类号： G01N21/17 , G01N21/23 , G01N21/21
摘要： The invention provides spectroscopy apparatuses and methods allowing precise overlapping between circularly polarized pump beam and a counter propagating linearly polarized probe beams in a sample which presents unique advantages for precision spectroscopy. In general, the apparatus comprises a phase retarding element with which by double pass by retro reflection of an incident beam turn linearly polarized light to circular and vice versa. This unique configuration enable to design a compact and miniature apparatus which may be applied for measuring polarization spectroscopy, nonlinear optical rotation and coherent population trapping phenomena with certain advantages resulting from the unique optical arrangement. The design of the apparatus further facilitates integration and scaling to produce arrays of units which may be particularly useful for magnetometry applications. Other important applications of the invention include laser frequency stabilization and atomic clocks.
摘要翻译：本发明提供了光谱设备和方法，其允许圆形极化的泵浦光束和样品中的反向传播的线性极化的探测光束之间的精确重叠，这对于精确光谱学具有独特的优点。通常，该装置包括相位延迟元件，利用该相位延迟元件，通过向后反射入射光束使得线性偏振光转向圆形，反之亦然。这种独特的配置使得能够设计紧凑和微型设备，该设备可以用于测量极化光谱学，非线性光学旋转和相干群体捕获现象，并由于独特的光学布置而具有某些优点。该设备的设计进一步便于集成和缩放以产生对于磁力测量应用特别有用的单元阵列。本发明的其他重要应用包括激光频率稳定和原子钟。

10. 发明申请

WO2010086852A1 A METHOD FOR MODIFYING COMPOSITE MEMBRANES FOR LIQUID SEPARATIONS 审中-公开
标题翻译：一种用于液体分离的复合膜的修改方法
公开(公告)号：WO2010086852A1
公开(公告)日：2010-08-05
申请号：PCT/IL2010/000071
申请日：2010-01-28
申请人： BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY , FREGER, Viatcheslav , BELFER, Sophia , BERENSTEIN, Roy
发明人： FREGER, Viatcheslav , BELFER, Sophia , BERENSTEIN, Roy
IPC分类号： B01D69/12 , B01D71/56 , B01D67/00
CPC分类号： B01D67/0093 , B01D69/125 , B01D71/56 , B01D2323/30 , B01D2323/38 , B01D2325/14 , B01D2325/16
摘要： A method for modifying the surface of nanofiltration (NF) and reverse osmosis (RO) composite membranes, comprising placing said composite membrane in a suitable vessel having a feed inlet opening and a permeate outlet opening, feeding an aqueous solution of one or more monomer(s) and free radical initiator into said vessel through said inlet opening, generating transmembrane pressure, thereby creating a flux across said membrane into said permeate outlet opening and causing said monomer(s) graft polymerize in the presence of said free radical initiator onto one face of said composite membrane.
摘要翻译：一种用于改变纳滤（NF）和反渗透（RO）复合膜表面的方法，包括将所述复合膜放置在合适的容器中，所述容器具有进料入口和渗透物出口，供给一种或多种单体的水溶液 s）和自由基引发剂通过所述入口开口引入所述容器，产生跨膜压力，由此产生穿过所述膜的通量进入所述渗透物出口，并使所述单体在所述自由基引发剂存在下接枝聚合到一个面的复合膜。

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