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1. 发明申请

WO2007027284A1 DEPLOYMENT SYSTEM FOR AN EXPANDABLE MEDICAL DEVICE 审中-公开
标题翻译：可扩展医疗器械的部署系统
公开(公告)号：WO2007027284A1
公开(公告)日：2007-03-08
申请号：PCT/US2006/024782
申请日：2006-06-26
申请人： GORE ENTERPRISE HOLDINGS, INC. , CULLY, Edward, H. , FLURY, Keith, M. , VONESH, Michael, J. , ARMSTRONG, Joseph, R.
发明人： CULLY, Edward, H. , FLURY, Keith, M. , VONESH, Michael, J. , ARMSTRONG, Joseph, R.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9517 , A61F2002/9583 , A61M25/10182
摘要： Deployment system for a self- expanding endoluminal device. The deployment system includes a confining sheath (12) placed around a compacted endoluminal device (14) so that upon deployment the sheath is transitioned into an internal deployment line housed within the catheter (19) . The deployment system is configured to prevent rotation of the catheter relative to the deployment line during deployment line actuation.
摘要翻译：自扩张腔内装置的部署系统。展开系统包括围绕压实的腔内装置（14）放置的限制护套（12），使得在展开时，护套被转变成容纳在导管（19）内的内部展开管线。部署系统被配置为在部署线致动期间防止导管相对于部署线旋转。

2. 发明申请

WO2006020425A1 BIOABSORBABLE SELF-EXPANDING ENDOLUMENAL DEVICES 审中-公开
标题翻译：可生物自扩张内镜装置
公开(公告)号：WO2006020425A1
公开(公告)日：2006-02-23
申请号：PCT/US2005/026892
申请日：2005-07-29
申请人： GORE ENTERPRISE HOLDINGS, INC. , ARMSTRONG, Joseph, R. , BEGOVAC, Paul, C. , CLEEK, Robert, L. , CULLY, Edward, H. , FLYNN, Charles , HAYES, Byron, K. , PETERSON, Ray, V. , VONESH, Michael, J. , WHITE, Charles, F.
发明人： ARMSTRONG, Joseph, R. , BEGOVAC, Paul, C. , CLEEK, Robert, L. , CULLY, Edward, H. , FLYNN, Charles , HAYES, Byron, K. , PETERSON, Ray, V. , VONESH, Michael, J. , WHITE, Charles, F.
IPC分类号： A61F2/06
CPC分类号： A61F2/01 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B2017/1205 , A61F2/91 , A61F2/915 , A61F2002/016 , A61F2002/018 , A61F2002/30062 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2210/0004 , A61F2210/0076 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0069 , A61F2230/008 , A61F2250/003 , A61L31/06 , A61L31/148 , C08L67/04
摘要： The present invention is directed to bioabsorbable self-expanding medical devices for use inside or outside body conduits that self-expand at, or below, normal human body temperature without requisite for a polymeric thermal transition.
摘要翻译：本发明涉及用于在正常人体温度下或在正常人体温度下自膨胀而不在聚合物热转变条件下自身膨胀的身体导管内部或外部的生物可吸收自扩张医疗装置。

3. 发明申请

WO2004064892A3 ADJUSTABLE LENGTH CATHETER 审中-公开
公开(公告)号：WO2004064892A3
公开(公告)日：2004-08-05
申请号：PCT/US2004/001242
申请日：2004-01-15
申请人： GORE ENTERPRISE HOLDINGS, INC. , ARMSTRONG, Joseph, R. , CULLY, Edward, H. , DAUGHERTY, John, R. , JOHNSON, Eric, G. , KING, David, R. , ULM, Mark, J. , VONESH, Michael, J.
发明人： ARMSTRONG, Joseph, R. , CULLY, Edward, H. , DAUGHERTY, John, R. , JOHNSON, Eric, G. , KING, David, R. , ULM, Mark, J. , VONESH, Michael, J.
IPC分类号： A61M25/01
摘要： A catheter provided with an adjustable length guidewire catheter lumen, located proximal of a therapeutic device or agent positioned at the distal end of the catheter. The length of the adjustable length guidewire catheter lumen is controlled by the physician, allowing the benefits of both over-the-wire and rapid exchange systems to be provided in one catheter. The adjustable length is provided with a thin-walled tube that corrugates under axial compression. The tube may optionally be pre-corrugated or may be allowed to corrugate non-uniformly under the axial compression. The catheter length may change by, for example, over 100 % of its original length between full axial compression and full axial extension.

4. 发明申请

WO2012096716A3 STENT 审中-公开
公开(公告)号：WO2012096716A3
公开(公告)日：2012-07-19
申请号：PCT/US2011/061165
申请日：2011-11-17
申请人： GORE ENTERPRISE HOLDINGS, INC. , ARMSTRONG, Joseph R. , CULLY, Edward H. , FRANKLIN, Michael W. , HANSEN, Mark Y. , LURIE, Brandon A. , MCMURRAY, Craig , MONTGOMERY, William D. , TERRY, Wendy J. , TITTELBAUGH, Eric M.
发明人： ARMSTRONG, Joseph R. , CULLY, Edward H. , FRANKLIN, Michael W. , HANSEN, Mark Y. , LURIE, Brandon A. , MCMURRAY, Craig , MONTGOMERY, William D. , TERRY, Wendy J. , TITTELBAUGH, Eric M.
IPC分类号： A61F2/90 , A61F2/06 , A61F2/82
摘要： The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by "open" cells and at least two end portions, defined by "closed" cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.

5. 发明申请

WO2006019626A3 DEPLOYMENT SYSTEM FOR INTRALUMINAL DEVICES 审中-公开
标题翻译：内窥镜装置部署系统
公开(公告)号：WO2006019626A3
公开(公告)日：2008-01-03
申请号：PCT/US2005024334
申请日：2005-07-08
申请人： GORE ENTERPRISE HOLDINGS INC , ARMSTRONG JOSEPH R
发明人： ARMSTRONG JOSEPH R
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12172 , A61B2017/00336 , A61B2017/12054 , A61B2017/12081 , A61B2090/037 , A61F2/95 , A61F2/958 , A61F2/966 , A61F2/97 , A61F2002/9511 , A61F2250/0071
摘要： A constraining sheath for use around an endoprosthesis (e.g., a sent device, with or without a graft covering), which may be a balloon expandable endoprosthesis but more preferably is a self-expanding prosthesis. The endoprosthesis is coaxially enclosed within and substantially covered by the constraining sheath, which is an outer, removable tubular sheath, preferably made of ePTFE. The sheath is preferably corrugated circumferentially along at least a portion of the length of the endoprosthesis. The constraining sheath and endoprosthesis are preferably mounted together as an assembly at the distal end of a delivery means such as a catheter shaft, for delivery of the endoprosthesis to a desired location within a body conduit such as an artery. The constraining sheath is removed by the application of tension to a tensile member such as a tether to cause sequential pulling out of the corrugations followed by release and deployment of the endoprosthesis. The use of a corrugated constraining sheath in comparison to a non-corrugated sheath results in a more smoothly applied tensile force to effect the endoprosthesis release as well as requiring less maximum force.
摘要翻译：用于内置假体周围使用的约束护套（例如，具有或不具有移植物覆盖物的送出的装置），其可以是球囊可扩张的内置假体，但更优选是自膨胀假体。内置假体同轴地封闭在约束鞘内并基本上被约束护套覆盖，约束护套是外部可移除的管状护套，优选由ePTFE制成。护套优选地沿着内置假体的长度的至少一部分周向地波纹。约束鞘和内假体优选地作为组件安装在诸如导管轴的输送装置的远端处，用于将内用假体递送到诸如动脉的体导管内的期望位置。通过施加张力将约束护套移除到诸如系绳的拉伸构件上，以引起连续拉出波纹，随后释放和展开内置假体。与非波纹护套相比，使用波纹约束护套导致更平滑地施加的拉力以实现内置假体释放以及需要较小的最大力。

6. 发明申请

WO2006019626A2 DEPLOYMENT SYSTEM FOR INTRALUMINAL DEVICES 审中-公开
标题翻译：内窥镜装置部署系统
公开(公告)号：WO2006019626A2
公开(公告)日：2006-02-23
申请号：PCT/US2005/024334
申请日：2005-07-08
申请人： GORE ENTERPRISE HOLDINGS, INC. , ARMSTRONG, Joseph, R.
发明人： ARMSTRONG, Joseph, R.
IPC分类号： A61F2/84
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12172 , A61B2017/00336 , A61B2017/12054 , A61B2017/12081 , A61B2090/037 , A61F2/95 , A61F2/958 , A61F2/966 , A61F2/97 , A61F2002/9511 , A61F2250/0071
摘要： A constraining sheath for use around an endoprosthesis (e.g., a sent device, with or without a graft covering), which may be a balloon expandable endoprosthesis but more preferably is a self-expanding prosthesis. The endoprosthesis is coaxially enclosed within and substantially covered by the constraining sheath, which is an outer, removable tubular sheath, preferably made of ePTFE. The sheath is preferably corrugated circumferentially along at least a portion of the length of the endoprosthesis. The constraining sheath and endoprosthesis are preferably mounted together as an assembly at the distal end of a delivery means such as a catheter shaft, for delivery of the endoprosthesis to a desired location within a body conduit such as an artery. The constraining sheath is removed by the application of tension to a tensile member such as a tether to cause sequential pulling out of the corrugations followed by release and deployment of the endoprosthesis. The use of a corrugated constraining sheath in comparison to a non-corrugated sheath results in a more smoothly applied tensile force to effect the endoprosthesis release as well as requiring less maximum force.
摘要翻译：用于内置假体周围使用的约束护套（例如，具有或不具有移植物覆盖物的送出的装置），其可以是球囊可扩张内置假体，但更优选是自膨胀假体。内置假体同轴地封闭在约束护套内，并且基本上被约束护套覆盖，约束鞘是外部可移除的管状护套，优选由ePTFE制成。护套优选地沿着内置假体的长度的至少一部分周向地波纹。约束鞘和内假体优选地作为组件安装在诸如导管轴的输送装置的远端处，用于将内用假体递送到诸如动脉的体导管内的期望位置。约束护套通过向拉伸构件（例如系绳）施加张力来移除，以引起连续拉出波纹，随后释放和展开内置假体。与非波纹护套相比，使用波纹约束护套导致更平滑地施加的拉力以实现内假体释放以及需要较小的最大力。

7. 发明申请

WO2004064892A2 ADJUSTABLE LENGTH CATHETER 审中-公开
标题翻译：可调节长度导管
公开(公告)号：WO2004064892A2
公开(公告)日：2004-08-05
申请号：PCT/US2004001242
申请日：2004-01-15
申请人： GORE ENTERPRISE HOLDINGS INC , ARMSTRONG JOSEPH R , CULLY EDWARD H , DAUGHERTY JOHN R , JOHNSON ERIC G , KING DAVID R , ULM MARK J , VONESH MICHAEL J
发明人： ARMSTRONG JOSEPH R , CULLY EDWARD H , DAUGHERTY JOHN R , JOHNSON ERIC G , KING DAVID R , ULM MARK J , VONESH MICHAEL J
IPC分类号： A61M25/00 , A61M25/09 , A61M
CPC分类号： A61M25/00 , A61M2025/0175
摘要： A catheter provided with an adjustable length guidewire catheter lumen, located proximal of a therapeutic device or agent positioned at the distal end of the catheter. The length of the adjustable length guidewire catheter lumen is controlled by the physician, allowing the benefits of both over-the-wire and rapid exchange systems to be provided in one catheter. The adjustable length is provided with a thin-walled tube that corrugates under axial compression. The tube may optionally be pre-corrugated or may be allowed to corrugate non-uniformly under the axial compression. The catheter length may change by, for example, over 100 % of its original length between full axial compression and full axial extension.
摘要翻译：设置有可调节长度的导丝导管腔的导管，位于位于导管远端的治疗装置或药剂的近侧。可调节长度的导丝导管管腔的长度由医生控制，允许在一个导管中提供超线和快速交换系统的益处。可调长度设置有在轴向压缩下波纹的薄壁管。管可以可选地是预波纹状的或者可以在轴向压缩下不均匀地起伏。导管长度可以在全轴向压缩和全轴向延伸之间改变例如其原始长度的100％以上。

8. 发明申请

WO2004064891A2 A PUNCTURABLE CATHETER 审中-公开
标题翻译：可调式导管
公开(公告)号：WO2004064891A2
公开(公告)日：2004-08-05
申请号：PCT/US2004/001241
申请日：2004-01-15
申请人： GORE ENTERPRISE HOLDINGS, INC. , ARMSTRONG, Joseph, R. , CULLY, Edward, H. , FLURY, Keith, M. , VONESH, Michael, J.
发明人： ARMSTRONG, Joseph, R. , CULLY, Edward, H. , FLURY, Keith, M. , VONESH, Michael, J.
IPC分类号： A61M
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物优选地是相对半透明的，允许良好地可视化导丝端部的位置，以使得能够沿着导管轴的长度在期望的位置刺穿覆盖物。覆盖物也优选在穿刺部位具有抗撕裂性。导管轴优选由具有对操作场提供良好可见性的颜色的材料制成，更优选地，全部或部分地是磷光。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

9. 发明申请

WO2004064891A3 A PUNCTURABLE CATHETER 审中-公开
标题翻译：可调式导管
公开(公告)号：WO2004064891A3
公开(公告)日：2005-06-02
申请号：PCT/US2004001241
申请日：2004-01-15
申请人： GORE ENTERPRISE HOLDINGS INC , ARMSTRONG JOSEPH R , CULLY EDWARD H , FLURY KEITH M , VONESH MICHAEL J
发明人： ARMSTRONG JOSEPH R , CULLY EDWARD H , FLURY KEITH M , VONESH MICHAEL J
IPC分类号： A61F2/958 , A61M20060101 , A61M5/00 , A61M25/00 , A61M25/14
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter (10) provided with a guidewire catheter lumen (18) having a thin covering (102) that is easily punctured by a guidewire (19) at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is also preferably tear resistant at puncture sites. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管（10）设置有导线导管管腔（18），其具有薄的覆盖物（102），其在导管长度的几乎任何所需点处被导丝（19）容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物也优选在穿刺部位具有抗撕裂性。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

10. 发明申请

WO2012096716A2 STENT 审中-公开
标题翻译：支架术
公开(公告)号：WO2012096716A2
公开(公告)日：2012-07-19
申请号：PCT/US2011061165
申请日：2011-11-17
申请人： GORE ENTERPRISE HOLDINGS INC , ARMSTRONG JOSEPH R , CULLY EDWARD H , FRANKLIN MICHAEL W , HANSEN MARK Y , LURIE BRANDON A , MCMURRAY CRAIG , MONTGOMERY WILLIAM D , TERRY WENDY J , TITTELBAUGH ERIC M
发明人： ARMSTRONG JOSEPH R , CULLY EDWARD H , FRANKLIN MICHAEL W , HANSEN MARK Y , LURIE BRANDON A , MCMURRAY CRAIG , MONTGOMERY WILLIAM D , TERRY WENDY J , TITTELBAUGH ERIC M
IPC分类号： A61F2/07 , A61F2/915 , A61F2/958 , A61F2/966
CPC分类号： A61F2/88 , A61F2/07 , A61F2/915 , A61F2/966 , A61F2002/075 , A61F2002/91558 , A61F2002/91575 , A61F2002/9583 , A61F2220/005 , A61F2220/0075 , A61F2230/0054
摘要： The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by "open" cells and at least two end portions, defined by "closed" cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.
摘要翻译：本发明涉及医疗装置及其使用方法。该装置是可以通过（或在）血管内导管或经由其它手术或其它技术经皮递送的支架，然后扩张。支架构造成具有由“开放”细胞限定的中心部分和由“封闭”细胞限定的至少两个端部，间隔开并直接连接到支架中心部分的远端和近端。支架也可任选地具有带开口的覆盖物或格子。

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