专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010042823A1 MULTIFUNCTIONAL SELF-ASSEMBLING POLYMERIC NANOSYSTEMS 审中-公开
标题翻译：多功能自组装聚合物纳米粒子
公开(公告)号：WO2010042823A1
公开(公告)日：2010-04-15
申请号：PCT/US2009/060175
申请日：2009-10-09
申请人： NORTHEASTERN UNIVERSTIY , AMIJI, Mansoor, M. , IYER, Arun, K.
发明人： AMIJI, Mansoor, M. , IYER, Arun, K.
IPC分类号： A61K9/00 , B82B3/00
CPC分类号： A61K9/1273 , A61K9/5161
摘要： Libraries of nanoparticles comprising therapeutic agents and/or imaging agents are disclosed, as well as methods of making, customizing, and using such libraries of nanoparticles.
摘要翻译：公开了包含治疗剂和/或成像剂的纳米颗粒的文库，以及制备，定制和使用这些纳米颗粒文库的方法。

2. 发明申请

WO2011119881A1 MULTI-COMPARTMENTAL MACROPHAGE DELIVERY 审中-公开
标题翻译：多层交付
公开(公告)号：WO2011119881A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/029860
申请日：2011-03-24
申请人： NORTHEASTERN UNIVERSITY , AMIJI, Mansoor, M. , KALARIYA, Mayur , JAIN, Shardool , ATTARWALA, Husain
发明人： AMIJI, Mansoor, M. , KALARIYA, Mayur , JAIN, Shardool , ATTARWALA, Husain
IPC分类号： A61K9/51 , A61K35/12
CPC分类号： A61K9/145 , A61K9/113 , A61K9/5031 , A61K9/5161 , A61K9/5169 , A61K38/191 , A61K38/217 , A61K39/39 , A61K47/6925 , A61K47/6935 , A61K49/0041 , A61K49/0047 , A61K49/0054 , A61K49/0076 , A61K49/0091 , A61K49/0093 , A61K2039/55555 , B82Y5/00
摘要： Disclosed are multi-compartmental nanoparticulate systems for imaging as well as the diagnosis, monitoring, and treatment of inflammation and/or disease. These multicompartmental nanoparticulate systems can be used to target specific cells or ceullular structures. Furthermore, these systems are capable of simultaneous delivery of hydrophilic and lipophilic compositions. Finally, these systems also allow for temporal control of drug delivery.
摘要翻译：公开了用于成像以及炎症和/或疾病的诊断，监测和治疗的多室纳米颗粒系统。这些多部分纳米颗粒系统可用于靶向特定细胞或者唾液结构。此外，这些系统能够同时递送亲水和亲脂性组合物。最后，这些系统还允许药物递送的时间控制。

3. 发明申请

WO2008153966A1 MUCOADHESIVE VESICLES FOR DRUG DELIVERY 审中-公开
公开(公告)号：WO2008153966A1
公开(公告)日：2008-12-18
申请号：PCT/US2008/007156
申请日：2008-06-06
申请人： BIOCURE, INC. , HIRT, Thomas , LU, Zhihua , MEIER, Wolfgang , AMIJI, Mansoor
发明人： HIRT, Thomas , LU, Zhihua , MEIER, Wolfgang , AMIJI, Mansoor
IPC分类号： A61K9/14 , A61K31/74
CPC分类号： A61K9/107 , A61K9/0053 , A61K47/34 , C08G77/452
摘要： Vesicles for delivery of active macromolecules which are formed from amphiphilic segmented copolymers having one or more mucoadhesive groups or regions and which can be used for delivery of an active agent to an area of the body having a mucous membrane, such as but not limited to the gastrointestinal tract.
摘要翻译：用于递送活性大分子的囊泡，其由具有一个或多个粘膜粘附基团或区域的两亲性分段共聚物形成，并且可用于将活性剂递送至具有粘膜的身体区域，例如但不限于胃肠道。

4. 发明申请

WO2021016457A1 METHODS OF CREATING A SUBSTANCE WITH DIFFERENT FREEZING POINTS BY ENCAPSULATION 审中-公开
公开(公告)号：WO2021016457A1
公开(公告)日：2021-01-28
申请号：PCT/US2020/043280
申请日：2020-07-23
申请人： THE GENERAL HOSPITAL CORPORATION , BRIXTON BIOSCIENCES, INC. , SABIR, Sameer , SIDOTI, Charles , AMIJI, Mansoor, M. , TAHA, Maie
发明人： ANDERSON, Richard, Rox , FARINELLI, William , GARIBYAN, Lilit
IPC分类号： A61K9/00 , A61K9/10 , A61K9/127 , A61K47/10 , A61K9/0019
摘要： The present disclosure relates to compositions and methods for manufacturing biomaterials that form flowable and injectable cold slurries. More particularly, the present disclosure relates to a composition containing a plurality of liposomes where the encapsulated internal liposomal media and external liposomal media have different freezing points.

5. 发明申请

WO2003059848A2 HYBRID IMMOBILIZED CATALYTIC SYSTEM WITH CONTROLLED PERMEABILITY 审中-公开
标题翻译：具有控制渗透性的混合式固定催化体系
公开(公告)号：WO2003059848A2
公开(公告)日：2003-07-24
申请号：PCT/US2003/000738
申请日：2003-01-10
申请人： NORTHEASTERN UNIVERSITY , AMIJI, Mansoor, M. , TAQIEDDIN, Ehab, S.
发明人： AMIJI, Mansoor, M. , TAQIEDDIN, Ehab, S.
IPC分类号： C07C
CPC分类号： A61K9/5036 , A61K9/0092 , A61K9/1652 , A61K9/7007 , A61K47/61 , C12N11/04 , C12N11/08
摘要： An immobilized catalytic system comprising a carrier layer containing a catalytic entity and a permeable screening layer for providing controlled access between the immobilizing catalytic entity and the surrounding environment and methods of making such systems are disclosed. The carrier layer includes the catalytic entity mixed with a neutral or anionic carrier polymer, which may or may not be cross-linked with a cross-linking agent. The carrier layer includes a matrix of a permeable to molecules processed by, produced by or acted upon by the catalytic entity but is not permeable to the catalytic entity itself. Any counter ion to neutral or anionic carrier polymer cannot be the same as the cationic polymer of the screening layer, and any counter ion to the cationic polymer cannot be the same as the neutral or anionic carrier polymer.
摘要翻译：公开了一种固定化的催化体系，其包括含有催化剂实体的载体层和用于在固定催化剂实体和周围环境之间提供受控进入的可渗透屏蔽层以及制造这种系统的方法。载体层包括与中性或阴离子载体聚合物混合的催化剂，其可以交联或不与交联剂交联。载体层包括由催化剂实体处理，由催化剂实体产生或经催化剂实体处理，但不能催化实体本身渗透的分子可渗透的基质。与中性或阴离子载体聚合物的任何反离子不能与筛选层的阳离子聚合物相同，并且任何与阳离子聚合物的反离子不能与中性或阴离子载体聚合物相同。

6. 发明申请

WO2011119822A1 MULTIMODAL DIAGNOSTIC TECHNOLOGY FOR EARLY STAGE CANCER LESIONS 审中-公开
标题翻译：多器官诊断技术用于早期癌症切除
公开(公告)号：WO2011119822A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/029777
申请日：2011-03-24
申请人： NORTHEASTERN UNIVERSITY , AMIJI, Mansoor, M. , GANTA, Srinivas , TSAI, Pei-Chin
发明人： AMIJI, Mansoor, M. , GANTA, Srinivas , TSAI, Pei-Chin
IPC分类号： A61B5/055
CPC分类号： A61K49/0091 , A61B5/0066 , A61K49/0032 , A61K49/0056 , A61K49/0058 , A61K49/0065 , G01N33/54346 , G01N33/587
摘要： Disclosed herein are compositions of a multimodal detection agent and methods of fabricating the same. The multimodal detection agent comprises a plurality of metallic nanoparticles attached to a surface of a polymeric carrier. The detection agent further comprising one or more target-specific binding agents attached to the metallic nanoparticles or the polymeric carrier.
摘要翻译：本文公开了多峰检测剂的组合物及其制造方法。多峰检测剂包括附着在聚合物载体表面上的多个金属纳米颗粒。检测剂还包含连接到金属纳米颗粒或聚合物载体上的一种或多种靶特异性结合剂。

7. 发明申请

WO2008147481A1 PRECISION-GUIDED NANOPARTICLE SYSTEMS FOR DRUG DELIVERY 审中-公开
标题翻译：用于药物递送的精确指导的纳米系统
公开(公告)号：WO2008147481A1
公开(公告)日：2008-12-04
申请号：PCT/US2008/001766
申请日：2008-02-11
申请人： NORTHEASTERN UNIVERSITY , HANSON, Robert, N. , AMIJI, Mansoor , WEISSIG, Volkmar
发明人： HANSON, Robert, N. , AMIJI, Mansoor , WEISSIG, Volkmar
IPC分类号： A01N25/26 , A01N25/28
CPC分类号： A61K49/0002 , A61K9/51 , A61K47/6923 , A61K47/6929 , A61K51/1244 , B82Y5/00
摘要： A method of preparing multifunctionalized nanoparticles involves using a modular system of half-linkers to attach functional moieties that serve to deliver the nanoparticles to a desired target, exert an effect at the target, or track the nanoparticles within a cell or an animal. The modular chemistry of the half-linker system permits the custom design and synthesis of functionalized nanoparticles bearing multiple groups and therefore results in precise delivery to desired cell types and intracellular locations. The functionalized nanoparticles can be used to treat or diagnose a variety of medical conditions, including neoplastic diseases, infectious diseases, and chronic diseases.
摘要翻译：制备多功能纳米颗粒的方法包括使用半连接体的模块化系统来附着功能部分，其用于将纳米颗粒递送至期望的靶，在靶处发挥作用，或跟踪细胞或动物内的纳米颗粒。半连接器系统的模块化化学允许定制设计和合成具有多个组的官能化纳米颗粒，因此导致精确递送到期望的细胞类型和细胞内位置。功能化纳米颗粒可用于治疗或诊断各种医疗状况，包括肿瘤疾病，传染病和慢性疾病。

8. 发明申请

WO2003059848A3 HYBRID IMMOBILIZED CATALYTIC SYSTEM WITH CONTROLLED PERMEABILITY 审中-公开
公开(公告)号：WO2003059848A3
公开(公告)日：2003-07-24
申请号：PCT/US2003/000738
申请日：2003-01-10
申请人： NORTHEASTERN UNIVERSITY , AMIJI, Mansoor, M. , TAQIEDDIN, Ehab, S.
发明人： AMIJI, Mansoor, M. , TAQIEDDIN, Ehab, S.
IPC分类号： G01N33/53
摘要： An immobilized catalytic system comprising a carrier layer containing a catalytic entity and a permeable screening layer for providing controlled access between the immobilizing catalytic entity and the surrounding environment and methods of making such systems are disclosed. The carrier layer includes the catalytic entity mixed with a neutral or anionic carrier polymer, which may or may not be cross-linked with a cross-linking agent. The screening layer over the carrier layer includes a matrix of a cationic polymer that is permeable to molecules processed by, produced by or acted upon by the catalytic entity but is not permeable to the catalytic entity itself. Any counter ion to the neutral or anionic carrier polymer cannot be the same as the cationic polymer of the screening layer, and any counter ion to the cationic polymer cannot be the same as the neutral or anionic carrier polymer.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式