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1. 发明申请

WO2021040903A2 POLYMER AMMUNITION HAVING AN ALIGNMENT AID, CARTRIDGE AND METHOD OF MAKING THE SAME 审中-公开
公开(公告)号：WO2021040903A2
公开(公告)日：2021-03-04
申请号：PCT/US2020/042258
申请日：2020-07-16
申请人： TRUE VELOCITY IP HOLDINGS, LLC
发明人： OVERTON, Christopher, William , ROSEK, Andrew , OVERTON, Kenneth, J. , HERZOG, Florian
IPC分类号： F42B5/307 , F42B5/313 , F42C19/08 , F42B5/00 , F42B5/02 , F42B5/26 , F42B33/00 , F42B7/06 , F42B5/30
摘要： One embodiment of the present invention provides a polymeric ammunition cartridge and methods of making and using the same. The cartridge includes a substantially cylindrical insert connected to a substantially cylindrical polymeric middle body. The substantially cylindrical insert includes a top surface opposite a bottom surface and a substantially cylindrical coupling element that extends from the bottom surface, a primer recess in the top surface that extends toward the bottom surface, a primer flash hole positioned in the primer recess to extend through the bottom surface, and a flange that extends circumferentially about an outer edge of the top surface. The substantially cylindrical polymeric middle body includes a substantially cylindrical polymeric bullet-end and a substantially cylindrical polymeric coupling end connected by a powder chamber, wherein the substantially cylindrical polymeric coupling end extends over the substantially cylindrical coupling element and covers a circumferential surface of the primer flash hole.

2. 发明申请

WO2020051174A1 REMOVABLE CONTAINER SHIPPING SAFETY FRAME FOR VEHICLE 审中-公开
公开(公告)号：WO2020051174A1
公开(公告)日：2020-03-12
申请号：PCT/US2019/049435
申请日：2019-09-04
申请人： SAER, Matt
发明人： SAER, Matt
IPC分类号： B60P3/073 , B60P3/08 , B65D85/68 , B65D88/12
摘要： The present invention provides an automated removable frame system for transporting vehicles in a container. The frame system is be assembled in the container, the vehicles are loaded on the frame system, the container is shipped to the location, the vehicles are unloaded from the frame system, and the frame system is disassembled and returned to the manufacture or stored for later use.

3. 发明申请

WO2020010096A9 MULTI-PIECE PRIMER INSERT FOR POLYMER AMMUNITION 审中-公开
公开(公告)号：WO2020010096A9
公开(公告)日：2020-01-09
申请号：PCT/US2019/040323
申请日：2019-07-02
申请人： TRUE VELOCITY IP HOLDINGS, LLC
发明人： BURROW, Lonnie , OVERTON, Christopher, William , HERZOG, Florian , MAMMOOTTIL, Nimmy , ROSEK, Andrew
IPC分类号： F42B33/00 , F42B5/30 , F42B5/307 , F42C19/08
摘要： The present invention provides a two piece and a three piece primer insert for ammunition piece. Each of the individual pieces may be formed by punching, pressing, stamping, molding, milling, coining, or by additive manufacturing. The individual pieces may be joined by clinching, pressing welding soldering, sintering, adhesive gluing, staking, and iterative addition by forming one piece into another piece.

4. 发明申请

WO2014062566A1 IMMUNOMODULATION USING SPORES AND POLLEN GRAINS 审中-公开
标题翻译：使用运动和花生颗粒进行免疫调节
公开(公告)号：WO2014062566A1
公开(公告)日：2014-04-24
申请号：PCT/US2013/064832
申请日：2013-10-14
申请人： TEXAS TECH UNIVERSITY SYSTEM , ATWE, Shashwati , GILL, Harvinder, S. , MA, Yunzhe
发明人： ATWE, Shashwati , GILL, Harvinder, S. , MA, Yunzhe
IPC分类号： A61K48/00 , A61K9/127 , A61K9/16 , A61K9/06 , A61P35/00
CPC分类号： A61K9/167 , A61K39/00 , A61K39/07 , A61K39/12 , A61K39/39 , A61K2039/542 , A61K2039/55588 , C12N2740/16034
摘要： The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen/spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen/spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner cavity and one or more antigens disposed on the outer surface, in the inner cavity, in the multiple pores, or a combination thereof, wherein the one or more antigens modulate an immune responses in the subject.
摘要翻译：本发明包括组合物，制备和使用该组合物以调节受试者的免疫应答的方法，其方法是提供一种疫苗组合物，该疫苗组合物具有置于药物载体中的用于递送至受试者的花粉/孢子，其中所述花粉/孢子包含多个孔其将花粉/孢子的外表面连接到内腔和设置在外表面，内腔中，多孔中或其组合中的一种或多种抗原，其中所述一种或多种抗原调节免疫应答在主题。

5. 发明申请

WO2012125894A2 OXIDATION INHIBITORS FOR AMINE DEGRADATION 审中-公开
标题翻译：氧化还原抑制剂
公开(公告)号：WO2012125894A2
公开(公告)日：2012-09-20
申请号：PCT/US2012/029367
申请日：2012-03-16
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , VOICE, Alexander, K. , ROCHELLE, Gary, T.
发明人： VOICE, Alexander, K. , ROCHELLE, Gary, T.
IPC分类号： C07C55/24 , C07F9/28 , C07C211/14 , B01D53/62
CPC分类号： C07F9/386 , B01D53/1462 , B01D2252/2023 , B01D2252/20405 , B01D2252/20442 , B01D2252/20447 , B01D2252/20484 , B01D2252/20489 , B01D2252/604 , B01D2252/606 , C07C59/265 , C07C215/10 , C07F9/3808 , Y02C10/04 , Y02C10/06 , Y02P20/152
摘要： Inhibitors and methods for preventing oxidative degradation in amine scrubbing system are disclosed herein. The substances disclosed in the present invention will be affective for aqueous solutions of other amines (particularly primary amines) prone to oxidation by molecular oxygen, as well as other concentrations of MEA, which are used in CO2 capture systems (namely 3-11 molal). The inhibitors disclosed herein include hydroxyethylidene diphosphonic acid (HEDP), diethylene triamine penta acetic acid (DPTA), diethylenetriamine penta (methylene phosphonic acid) (DTPMP), ethylenediamine tetra (methylene phosphonic acid) (EDTMP), and citric acid. The compounds of the present invention act as potent chelating agents to sequester metal ions and prevent metal-catalyzed homolytic decomposition of reactive peroxides in solution, thus preventing amine oxidation.
摘要翻译：本文公开了用于防止胺洗涤系统中的氧化降解的抑制剂和方法。本发明公开的物质对于易于被分子氧氧化的其它胺（特别是伯胺）的水溶液以及用于二氧化碳捕集系统中的其它浓度的MEA（即3-11摩尔）将是有意义的，。本文公开的抑制剂包括羟乙叉二膦酸（HEDP），二亚乙基三胺五乙酸（DPTA），二亚乙基三胺五（亚甲基膦酸）（DTPMP），乙二胺四（亚甲基膦酸）（EDTMP）和柠檬酸。本发明的化合物充当螯合剂螯合金属离子并防止溶液中金属催化的反应性过氧化物的分解，从而防止胺氧化。

6. 发明申请

WO2008036953A8 IN VIVO TRANSFORMATION OF PANCREATIC ACINAR CELLS INTO INSULIN-PRODUCING CELLS 审中-公开
公开(公告)号：WO2008036953A8
公开(公告)日：2008-03-27
申请号：PCT/US2007/079242
申请日：2007-09-21
申请人： BAYLOR RESEARCH INSTITUTE , GRAYBURN, Paul, A. , CHEN, Shuyuan
发明人： GRAYBURN, Paul, A. , CHEN, Shuyuan
IPC分类号： C12N15/00 , C12N5/00 , C12N5/02 , C07H21/02 , C07H21/04
摘要： The present invention includes compositions and methods for transforming cells into glucose- responsive, insulin-production cells using a construct that expresses betacellulin and PDXl, e.g., transforming pancreatic acinar cells using one or more expression vectors that expressed betacellulin and PDXl using ultrasound targeted microbubble destruction (UTMD).

7. 发明申请

WO2008024642A2 GENE EXPRESSION SIGNATURES IN BLOOD LEUKOCYTES PERMIT DIFFERENTIAL DIAGNOSIS OF ACUTE INFECTIONS 审中-公开
标题翻译：白血病基因表达标志允许急性感染的差异性诊断
公开(公告)号：WO2008024642A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/075713
申请日：2007-08-10
申请人： BAYLOR RESEARCH INSTITUTE , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , BANCHEREAU, Jacques, F. , PALUCKA, Anna, Karolina , RAMILO, Octavio , CHAUSSABEL, Damien
发明人： BANCHEREAU, Jacques, F. , PALUCKA, Anna, Karolina , RAMILO, Octavio , CHAUSSABEL, Damien
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/156 , C12Q2600/158
摘要： The present invention includes compositions, systems and methods for the early detection and consistent determination of the extent, type and nature of a host immune response and the nature of the infectious disease using gene expression data.
摘要翻译：本发明包括使用基因表达数据早期检测和一致确定宿主免疫应答的程度，类型和性质以及感染性疾病的性质的组合物，系统和方法。

8. 发明申请

WO2022212826A1 MODULAR UMBRELLA 审中-公开
公开(公告)号：WO2022212826A1
公开(公告)日：2022-10-06
申请号：PCT/US2022/023028
申请日：2022-04-01
申请人： LAPORTE, Darren
发明人： LAPORTE, Darren
IPC分类号： E04H15/48 , A45B25/14 , A45B25/00 , A45B25/06 , A45B25/08 , A45B25/22 , A45B15/00 , A45B2023/0012 , A45B2200/1063 , A45B23/00 , A45B25/02 , E04H12/2246 , E04H12/2269
摘要： The present invention includes a modular umbrella comprising: an umbrella frame comprising: an upper hub attached to a first end of a support pole, a plethora of upper hinge connectors pivotably positioned radially around the upper hub; an upper support portion connected to each of the plethora of upper hinge connectors to extend radially from the upper hub; a lower support portion connected to each of the upper support portions; a sliding coupler attached to each of the upper support portions; a support arm connected to each of the sliding couplers; a lower hinge connector connected to each of the support arms; a lower hub slidable positioned around the support pole and connected to each of the lower hinge connectors wherein the lower hinge connectors are pivotably connected radially around the lower hub, wherein the lower hub moves up or down which moves the support arm to extend the upper support portion; a base that supports a second end of the support pole wherein the base comprises a top plate having a top plate support pole aperture through the top plate to allow passage of the support pole through the top plate; a bottom plate opposite the top plate; a support pole receiver connected to the bottom plate and aligned to receive the second end of the support pole; a first platform support connected to the bottom plate and to the top plate to separate the bottom plate and the top plate; and a second platform support connected to the bottom plate and to the top plate to separate the bottom plate and the top plate wherein the second platform support is positioned opposite the first platform support.

9. 发明申请

WO2022132120A1 DIRECT CARDIAC COMPRESSION DEVICE WITH IMPROVED DURABILITY 审中-公开
公开(公告)号：WO2022132120A1
公开(公告)日：2022-06-23
申请号：PCT/US2020/053920
申请日：2020-12-14
申请人： THE TEXAS A&M UNIVERSITY SYSTEM , CORINNOVA INCORPORATED
发明人： CRISCIONE, John, C. , HORD, Erica, Christine , MCDOWALL, Michael
IPC分类号： A61M1/12 , A61F2/02 , A61F2/24 , A61F5/34 , A61H31/00 , A61M1/10
摘要： The present invention provides a direct cardiac compression device comprising one or more passive chambers that taper from an aperture to an apex; one or more inflatable active pockets individually independently inflatable, wherein each of the one or more inflatable active pockets is connected to the one or more passive chambers at least partially from the aperture to the apex and wherein the each of the one or more inflatable active pockets does not tension the adjacent one or more inflatable active pockets upon inflation; and a frame in contact with the one or more active chambers to at least partially surround the one or more active pockets.

10. 发明申请

WO2020139453A2 A METHOD FOR INCREASING ROMIDEPSIN PRODUCTION FROM FERMENTATION BROTH 审中-公开
公开(公告)号：WO2020139453A2
公开(公告)日：2020-07-02
申请号：PCT/US2019/058493
申请日：2019-10-29
申请人： MARRONE BIO INNOVATIONS, INC.
发明人： ODDONE, Gian , BLODGETT, Jacob , REVELES, Raul
IPC分类号： C12N1/20
摘要： The present invention includes a method to increase romidepsin concentration in a bacteria fermentation media. Romidepsin concentration in a fermentation is increased by adding, for example, copper sulfate. The end resulting romidepsin concentration is increased by at least about two fold as compare to fermentation without copper sulfate.

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