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1. 发明申请

WO2018005581A1 DYNAMIC EFFECTIVE RADIATED POWER (ERP) ADJUSTMENT 审中-公开
标题翻译：动态有效的辐射功率（ERP）调整
公开(公告)号：WO2018005581A1
公开(公告)日：2018-01-04
申请号：PCT/US2017/039625
申请日：2017-06-28
申请人： GOGO LLC
发明人： DANG, Tuan, M. , CORDONE, Sean, S. , BRUGGEMANN, Jeff
IPC分类号： H04B7/185
摘要： Antennas used aboard aircraft to communicate with satellites or ground stations may have complex antenna patterns, which may vary as the aircraft moves throughout a given coverage area. Techniques are disclosed for dynamically adjusting the instantaneous power fed to an antenna system to ensure that the antenna transmits at the regulatory or coordinated effective isotropic radiated power (EIRP) spectral limit. The antenna may transmit, in accordance with aircraft location and attitude, steerable beam patterns at different scan and skew angle combinations, causing variations in antenna gain and fluctuations in the transmitted EIRP. Using on-board navigational data, an antenna gain and ESD limit may be calculated for a particular scan and skew angle, which may be used to adjust power fed to the antenna such that the antenna transmits substantially at maximum allowable EIRP as the steerable beam pattern is adjusted.
摘要翻译：在飞机上用于与卫星或地面站通信的天线可能具有复杂的天线方向图，当飞机在给定的覆盖区域内移动时，天线方向图可能会有所不同。公开了用于动态调整馈送到天线系统的瞬时功率以确保天线以调节或协调的有效各向同性辐射功率（EIRP）频谱限制发射的技术。根据飞机位置和姿态，天线可以在不同的扫描和倾斜角度组合处传输可控波束方向图，引起天线增益的变化和传输的EIRP的波动。使用机载导航数据，可以针对特定的扫描和倾斜角来计算天线增益和ESD极限，其可以用于调整馈送给天线的功率，使得天线基本上以最大可允许的EIRP传输作为可控波束图案被调整。

2. 发明申请

WO2016209631A1 SINGLE-EMITTER LIGHTING DEVICE THAT OUTPUTS A MINIMUM AMOUNT OF POWER TO PRODUCE INTEGRATED RADIANCE VALUES SUFFICIENT FOR DEACTIVATING PATHOGENS 审中-公开
标题翻译：产生最小功率的单发射灯装置，以产生一体化辐射值，用于抵抗病原体
公开(公告)号：WO2016209631A1
公开(公告)日：2016-12-29
申请号：PCT/US2016/036704
申请日：2016-06-09
申请人： KENALL MANUFACTURING COMPANY
发明人： HAWKINS, James, W. , HEIKING, Nathan, D.
IPC分类号： H05B37/02 , H05B33/08 , A61L2/08 , A61L9/18 , A61N5/06 , F21K9/00 , F21V23/04 , F21V33/00 , H01L33/50 , F21W131/20
CPC分类号： A61L2/084 , A61L2/24 , A61L9/18 , A61L9/20 , A61L2202/11 , A61L2202/14 , A61L2202/25 , A61L2209/111 , A61L2209/12 , A61N5/06 , A61N5/0624 , A61N2005/0662 , F21K9/00 , F21S8/026 , F21V5/04 , F21V7/00 , F21V15/01 , F21V19/006 , F21V23/0442 , F21V23/0471 , F21V23/06 , F21V29/70 , F21V31/005 , F21V33/0068 , F21W2131/20 , F21Y2101/00 , F21Y2105/10 , F21Y2113/00 , F21Y2113/13 , F21Y2115/10 , H01L33/50 , H05B33/0854 , H05B33/0872 , H05B33/0884 , H05B37/02 , H05B37/0227 , H05B37/0272
摘要： A lighting device configured to deactivate dangerous pathogens (e.g., MRSA bacteria) in an environment. The lighting device includes at least one lighting element (656) configured to provide light and a wavelength converting element (657), wherein at least a first component (700) of the light comprising light having a wavelength of between 400 nm and 420 nm, and at least a second component (704) of the light is converted into light having a wavelength of greater than 420 nm. The first component (700) of light has a minimum integrated irradiance of.05 mW/cm 2 measured from any unshielded point in the environment that is 1.5 m from any point on any external-most luminous surface of the lighting device.
摘要翻译：一种被配置为在环境中停用危险病原体（例如，MRSA细菌）的照明装置。照明装置包括配置成提供光的至少一个照明元件（656）和波长转换元件（657），其中包括波长在400nm和420nm之间的光的至少第一组分（700）并且光的至少第二组分（704）被转换成波长大于420nm的光。光的第一组分（700）具有从环境中的任何非屏蔽点测量的最小积分辐照度为0.05mW / cm 2，该照明装置的任何外部最发光表面上的任何点为1.5μm。

3. 发明申请

WO2022066418A1 METHODS AND SYSTEMS FOR DETERMINING A MINIMUM NUMBER OF CELL LINE CLONES NECESSARY TO PRODUCE A PRODUCT HAVING A SET OF TARGET PRODUCT ATTRIBUTES 审中-公开
公开(公告)号：WO2022066418A1
公开(公告)日：2022-03-31
申请号：PCT/US2021/049562
申请日：2021-09-09
申请人： AMGEN INC.
发明人： LE, Huong, Thi Ngoc , TAT, Jasmine , ZASADZINSKA, Ewelina
IPC分类号： G16B40/00 , C12M1/00
摘要： Methods and systems for determining a minimum number of cell line clones necessary to produce a product having a set of target product attributes are disclosed. An example method includes generating at least one cell line capable of expressing a polypeptide; measuring, using one or more analytical instruments, a plurality of measured product attribute values of a plurality of clones of a candidate cell line; receiving inputs, via a user interface, representing a set of target product attribute values for a product; projecting, by one or more processors based upon the plurality of measured values, a minimum number of subject clones of the product using the candidate cell line necessary to produce a subset of the subject clones having product attributes that satisfy one or more conditions associated with the set of target values; and generating the projected minimum number of subject clones of the product using the candidate cell line.

4. 发明申请

WO2016209633A1 METHOD OF PROVIDING DOSES OF LIGHT SUFFICIENT TO DEACTIVATE DANGEROUS PATHOGENS THROUGHOUT A VOLUMETRIC SPACE OVER A PERIOD OF TIME 审中-公开
标题翻译：提供轻度剂量以消除危险病原体的方法，通过一段时间内的体积空间
公开(公告)号：WO2016209633A1
公开(公告)日：2016-12-29
申请号：PCT/US2016/036722
申请日：2016-06-09
申请人： KENALL MANUFACTURING COMPANY
发明人： HAWKINS, James, W. , YAHNKE, Clifford, J.
IPC分类号： A61L2/24 , A61L2/08 , H05B37/02 , H05B33/08 , F21K9/00 , F21V23/04 , F21V33/00 , A61N5/06
CPC分类号： A61L2/084 , A61L2/24 , A61L9/18 , A61L9/20 , A61L2202/11 , A61L2202/14 , A61L2202/25 , A61L2209/111 , A61L2209/12 , A61N5/06 , A61N5/0624 , A61N2005/0662 , F21K9/00 , F21S8/026 , F21V5/04 , F21V7/00 , F21V15/01 , F21V19/006 , F21V23/0442 , F21V23/0471 , F21V23/06 , F21V29/70 , F21V31/005 , F21V33/0068 , F21W2131/20 , F21Y2101/00 , F21Y2105/10 , F21Y2113/00 , F21Y2113/13 , F21Y2115/10 , H01L33/50 , H05B33/0854 , H05B33/0872 , H05B33/0884 , H05B37/02 , H05B37/0227 , H05B37/0272
摘要： A method of providing doses of light sufficient to deactivate bacteria throughout a volumetric space over a period of time, the method comprising: - receiving first data associated with a desired illuminance level for the space, second data indicative of an estimated occupancy of the volumetric space over a predetermined period of time, and third data indicative of the dimensions of the space; - determining, based on the first data, an arrangement of one or more lighting fixtures in the volumetric space, the one or more lighting fixtures configured to at least partially emit disinfecting light having a wavelength of between 400 nm and 420 nm; - determining based on the second and third data a total radiometric power to be applied via the one or more lighting fixtures to produce a desired power density at any exposed surface within the volumetric space during the period of time, the desired power density comprising a minimum integrated irradiance of the disinfecting light equal to 0.01 mW/cm 2 ; - installing the determined arrangement of one or more lighting fixtures in the volumetric space and - applying the determined total radiometric power to the volumetric space via the one or more lighting fixtures.
摘要翻译：一种提供足以在一段时间内在整个体积空间中去激活细菌的光量的方法，所述方法包括： - 接收与所述空间的期望照度水平相关联的第一数据，第二数据指示体积空间的估计占用超过预定时间段，以及指示空间尺寸的第三数据; - 基于所述第一数据确定所述体积空间中的一个或多个照明器具的布置，所述一个或多个照明器具被配置为至少部分地发射波长在400nm和420nm之间的消毒光; - 基于所述第二和第三数据确定要经由所述一个或多个照明器具施加的总辐射功率以在所述时间段期间在所述体积空间内的任何暴露表面处产生期望功率密度，所述期望功率密度包括最小值消毒光的积分辐照度等于0.01 mW / cm2; - 将所确定的一个或多个照明器具的布置安装在所述体积空间中，以及 - 经由所述一个或多个照明器具将确定的总辐射功率施加到所述容积空间。

5. 发明申请

WO2016209632A1 LIGHTING DEVICE THAT DEACTIVATES DANGEROUS PATHOGENS WHILE PROVIDING VISUALLY APPEALING LIGHT 审中-公开
标题翻译：在提供视觉上光的情况下消除危险病害的照明设备
公开(公告)号：WO2016209632A1
公开(公告)日：2016-12-29
申请号：PCT/US2016/036710
申请日：2016-06-09
申请人： KENALL MANUFACTURING COMPANY
发明人： MARRY, Patrick, J. , HEIKING, Nathan, D. , DYKSTRA, Keith, H.
IPC分类号： H05B37/02 , H05B33/08 , A61L2/08 , A61L9/18 , A61N5/06 , F21K9/00 , F21V23/04 , F21V33/00 , H01L33/50 , F21W131/20
CPC分类号： A61L2/084 , A61L2/24 , A61L9/18 , A61L9/20 , A61L2202/11 , A61L2202/14 , A61L2202/25 , A61L2209/111 , A61L2209/12 , A61N5/06 , A61N5/0624 , A61N2005/0662 , F21K9/00 , F21S8/026 , F21V5/04 , F21V7/00 , F21V15/01 , F21V19/006 , F21V23/0442 , F21V23/0471 , F21V23/06 , F21V29/70 , F21V31/005 , F21V33/0068 , F21W2131/20 , F21Y2101/00 , F21Y2105/10 , F21Y2113/00 , F21Y2113/13 , F21Y2115/10 , H01L33/50 , H05B33/0854 , H05B33/0872 , H05B33/0884 , H05B37/02 , H05B37/0227 , H05B37/0272
摘要： A lighting device configured to deactivate pathogens in an environment. The lighting device includes at least one first light-emitting element (256) configured to emit light having a wavelength of between 400 nm and 420 nm, wherein the light emitted by the at least one first light-emitting element is configured to deactivate the pathogens in the environment. The lighting device also includes at least one second light-emitting element (260) configured to emit light having a wavelength of greater than 420 nm. A first combined light output of the light emitted by the at least one first and the at least one second light-emitting elements includes visible light that is perceived as white light. The white light has properties that make it visually appealing and unobjectionable.
摘要翻译：配置成在环境中停用病原体的照明装置。照明装置包括配置成发射波长在400nm和420nm之间的光的至少一个第一发光元件（256），其中由至少一个第一发光元件发射的光被配置为使病原体失活在环境中。照明装置还包括配置成发射波长大于420nm的光的至少一个第二发光元件（260）。由至少一个第一发光元件和至少一个第二发光元件发射的光的第一组合光输出包括被感知为白光的可见光。白光具有使其视觉吸引力和无反感的性质。

6. 发明申请

WO2011006021A1 APPARATUS AND METHOD FOR BARCODED MAGNETIC BEADS ANALYSIS 审中-公开
标题翻译：用于骨架磁珠分析的装置和方法
公开(公告)号：WO2011006021A1
公开(公告)日：2011-01-13
申请号：PCT/US2010/041444
申请日：2010-07-08
申请人： APPLIED BIOCODE INC. , HO, Winston, Z. , COLLINS, John , HOU, Chung-Jen
发明人： HO, Winston, Z. , COLLINS, John , HOU, Chung-Jen
IPC分类号： C12Q1/68 , G01N33/53 , G06K7/10
CPC分类号： G06K19/06028 , B01J2219/00497 , B01J2219/00547 , B01J2219/00585 , B01J2219/00605 , B01J2219/00693 , B01J2219/00722 , B01L3/54 , C40B20/04 , C40B50/16
摘要： A Light Transmitted Assay Beads or digital magnetic microbead having a digitally coded structure that is partially transmissive and opaque to light. When hundreds or thousands of LITAB are settled down to the bottom of a micro well in a microplate or a planar surface, the barcode can be decoded by image processed accurately and reliable. Microplate is a standard bioassay format. Therefore, a large number of targets in a sample can be analyzed in one single microwell. The image decoding algorithms comprise of four main processes enhancement of image segmentation of beads extraction of barcode slits, and decoding of barcodes. The bead image is taken from the bottom of an optically clear microplate, and barcode pattern can be decoded by image software. Therefore, the whole bead bioassay experiment can be performed in the microplate without taking the beads out.
摘要翻译：光透射测定具有数字编码结构的珠或数字磁微珠，其部分透射并且对于光不透明。当数百或数千个LITAB沉降到微板或平面表面的微孔底部时，可以通过精确可靠的图像进行解码。微孔板是标准的生物测定方法。因此，可以在单个微孔中分析样品中的大量靶标。图像解码算法包括四个主要过程，增强条形码切片的珠提取图像分割，以及条形码解码。从光学透明微板的底部取出珠粒图像，并且可以通过图像软件对条形码图案进行解码。因此，可以在微量培养板中进行全部小珠生物测定实验，而不用将珠子取出。

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