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1. 发明申请

WO2023026281A1 A METHOD OF PLANT TREATMENT WITH 8-GERANYL-7-HYDROXYCOUMARIN AND PESTICIDE COMPOSITIONS THEREOF 审中-公开
公开(公告)号：WO2023026281A1
公开(公告)日：2023-03-02
申请号：PCT/IL2022/050916
申请日：2022-08-22
申请人： METABOLIC INSIGHTS LTD.
发明人： PANIK, David , KORMAN, Ido
IPC分类号： A01N43/16 , A01P3/00
摘要： A method for controlling, preventing, reducing or eradicating the instances of plant-pathogen infestation or plant diseases on a plant, plant organ, plant part, or plant propagation material is provided. The method comprises applying to a plant, plant part, plant organ or plant propagation material, or to soil surrounding said plant, a pesticidally effective amount of 8-geranyl-7- hydroxycoumarin or a pesticide composition comprising it, wherein said plant-pathogen is a member selected from a Basidiomycota of the class Agaricomycetes or the genus Rhizoctonia, an Ascomycota of the class Sordariomycetes or a genus selected from Fusarium, Heterokontophyta of the class Oomycota and a Heterokontophyta of the order Peronosporales.

2. 发明申请

WO2022091102A1 METHOD FOR REDUCING POST-OPERATIVE SCAR FORMATION USING MATERIALS COMPRISING COPPER, ZINC AND/OR SILVER COMPOUNDS APPLIED UNDER PERIPHERAL PRESSURE 审中-公开
公开(公告)号：WO2022091102A1
公开(公告)日：2022-05-05
申请号：PCT/IL2021/051285
申请日：2021-10-31
申请人： MEDCU TECHNOLOGIES LTD
发明人： LUSTIGER, Danny , BORKOW, Gadi
IPC分类号： A61L15/18 , A61L15/42
摘要： A method for reducing post-operative scar formation on a skin of a patient comprises applying a composition or material comprising copper, zinc and/or silver compounds to a postoperative wound under continuous peripheral pressure to the surgical incision and surrounding inflamed tissue, in order to reduce the inflammatory response, improve wound healing, reduce wounds complications and improve scar formation.

3. 发明申请

WO2020016887A1 OPTICAL DEVICES AND METHODS FOR MEASURING EFFICIENCY OF THE FӦRSTER RESONANCE ENERGY TRANSFER 审中-公开
公开(公告)号：WO2020016887A1
公开(公告)日：2020-01-23
申请号：PCT/IL2019/050794
申请日：2019-07-15
申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
发明人： SHERMAN, Eilon , TSIPSHTEIN, Shai
IPC分类号： C12Q1/6818 , G01N21/64 , G01N33/542
摘要： The present invention relates to an optical device and methods employed by the device to image and measure single intermolecular interactions in cells, particularly in densely-labelled cells, and to further determine the intramolecular distance between the donor- and the acceptor-labelled molecules with the Angstrom resolution. The device and the methods are based on the combination of the frustrated Forster resonance energy transfer (f/FRET) and single molecule localisation microscopy (SMLM) technique with the lock-in detection. For the first time, a super-resolved optical image of a cell in single molecule detail and with distance measurements that continuously span Angstroms to microns is provided by the present invention. The device of the present invention is configured to use smartphone technologies, such as the CMOS camera chip and smartphone processor for acquisition of the single molecule images and analysis of the inter- molecular interactions, and can be used for point-of-care diagnostics.

4. 发明申请

WO2018055610A1 NON-TRACKING SOLAR ENERGY COLLECTOR 审中-公开
标题翻译：非追踪太阳能收集器
公开(公告)号：WO2018055610A1
公开(公告)日：2018-03-29
申请号：PCT/IL2017/050999
申请日：2017-09-06
申请人： B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY
发明人： NIV, Avi , FRENKEL, Ido
IPC分类号： H01L27/30 , G01J1/04
摘要： The present application describes embodiments of a non-tracking solar energy collector comprising: (a) at least one solar radiation concentrator for collimating and directing the incident solar radiation rays to at least one focal point along the surface of a reactive reflector; (b) the reactive reflector mounted on top of an external cavity and having at least one transparency zone instantly formed at said at least one focal point of the solar radiation rays, for letting the solar radiation rays enter said external cavity, wherein said transparency zone is constantly moving along the surface of said reactive reflector following the position of said at least one focal point of the solar radiation rays; and (c) the external cavity containing a solar cell and capable of trapping the entered solar radiation rays by inner scattering of said solar radiation rays on the walls of said external cavity, wherein said inner scattering of said solar radiation rays inside said external cavity is preventing solar radiation to escape from said solar cell, thereby minimising solar radiation losses.
摘要翻译：本申请描述了非追踪太阳能收集器的实施例，其包括：（a）至少一个太阳辐射集中器，用于将入射太阳辐射射线准直并引导至沿表面的至少一个焦点的无源反射器; （b）安装在外部空腔顶部并且具有至少一个立即在太阳辐射射线的所述至少一个焦点处形成的透明区域的反应性反射器，用于使太阳辐射射线进入所述外部空腔，其中所述透明区域不断沿着所述无功反射器的表面跟随所述太阳辐射射线的所述至少一个焦点的位置移动; （c）包含太阳能电池并且能够通过所述太阳辐射射线在所述外腔的壁上的内散射来俘获进入的太阳辐射射线的外腔，其中所述外腔内的所述太阳辐射射线的所述内部散射是防止太阳辐射从所述太阳能电池逸出，从而使太阳辐射损失最小化。

5. 发明申请

WO2017072774A1 PHARMACEUTICAL COMPOSITIONS FOR TRANSMUCOSAL DELIVERY 审中-公开
标题翻译：用于透皮递送的药物组合物
公开(公告)号：WO2017072774A1
公开(公告)日：2017-05-04
申请号：PCT/IL2016/051167
申请日：2016-10-28
申请人： SOLUBEST LTD
发明人： TEMTSIN-KRAYZ, Galia , GLOZMAN, Sabina , KAZHDAN, Pavel
IPC分类号： A61K47/30 , A61K47/34 , A61K47/36 , A61K47/42 , A61K9/20
CPC分类号： A61K9/006 , A61K9/1611 , A61K9/1623 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K9/2009 , A61K9/2018 , A61K9/2031 , A61K9/2054 , A61K9/2059 , A61K31/05 , A61K31/352 , A61K31/4045 , A61K31/5377 , A61K31/573 , A61K38/28
摘要： The present application relates to a pharmaceutical composition for transmucosal administration of an active lipophilic compound through the oral mucosa comprising a lipophilic active compound, a polymeric matrix formed by two or more water-soluble polymers and a rapid dissolution agent. At least one of the water-soluble polymers is an amphiphilic polymer and at least one is either a hydrophilic polymer or an amphiphilic polymer with a hydrophobic-hydrophilic balance different from the first amphiphilic polymer. In addition, the polymeric matrix is not crosslinked and no covalent interaction occurs between the two or more polymers and between the polymers and the lipophilic active compound, which is interwoven with the aforesaid polymeric matrix.
摘要翻译：本申请涉及通过口腔粘膜透粘膜给予活性亲脂性化合物的药物组合物，其包含亲脂性活性化合物，由两种或更多种水溶性聚合物形成的聚合物基质和快速溶解剂。至少一种水溶性聚合物是两亲聚合物，并且至少一种是亲水聚合物或具有不同于第一种两亲聚合物的疏水 - 亲水平衡的两亲聚合物。此外，聚合物基质不交联，并且在两种或更多种聚合物之间以及聚合物与与上述聚合物基质交织的亲脂性活性化合物之间不发生共价相互作用。

6. 发明申请

WO2020070749A1 AN OPTICAL DEVICE CAPABLE OF RESPONDING TO A WRITING LONG-WAVE RADIATION 审中-公开
公开(公告)号：WO2020070749A1
公开(公告)日：2020-04-09
申请号：PCT/IL2019/051087
申请日：2019-10-06
申请人： ABDULHALIM, Ibrahim , ABDULHALIM, Hisham
发明人： ABDULHALIM, Ibrahim , ABDULHALIM, Hisham
IPC分类号： G02B23/12 , G02F1/13 , H04N5/33
摘要： The present invention relates to an optical imaging device capable of responding to a writing long wave radiation (w) emitted by any object or scene. Said device is configured to operate in reflection mode or in transmission mode and comprises a reading light unit (2), writing light unit (4), resonant optically-addressed spatial light modulator (ROASLM) (3) with an optically-responsive resonant structure (ORRS) (100) and a detector (40), wherein said (ORRS) (100) comprises: a photosensitive layer (101) deposited on a transparent substrate for absorbing the writing radiation (w) in a form of the long-wave image of the object or scene (1) and transforming said image into the stimulating signal across the ORRS (100), optical layers (102) for inducing resonance effect to the stimulating signal formed in the ORRS (100), optional alignment layers (103) for aligning liquid crystal molecules, and the conversion layer (104) for converting the resonant long-wave image of the object or scene (1) into a visible-range image.

7. 发明申请

WO2019038756A1 DRY POWDER COMPOSITIONS FOR INTRANASAL DELIVERY 审中-公开
公开(公告)号：WO2019038756A1
公开(公告)日：2019-02-28
申请号：PCT/IL2018/050914
申请日：2018-08-19
申请人： SOLUBEST LTD.
发明人： TEMTSIN-KRAYZ, Galia
IPC分类号： A61K9/12 , A61K9/14 , A61K47/36
摘要： The present application relates to a pharmaceutical composition in a form of dry powder for intranasal administration, comprising solid particles of at least one active agent and solid particles of a diluent, said pharmaceutical composition being substantially free of excipients other than the solid diluent, wherein said pharmaceutical composition having at least 90% of the particles of said at least one active agent with a mean particle size of 10-30 microns and less than 10% of the particles of said at least one active agent with a mean particle size equal to or below 5 microns. The particles of said diluent have a mean particle size of 30-200 microns. The present application also relates to an apparatus and modified spray drying method for preparation of the pharmaceutical composition of the present invention in the dry powder form.

8. 发明申请

WO2017033184A1 RESONANT PERIODIC STRUCTURES AND METHODS OF USING THEM AS FILTERS AND SENSORS 审中-公开
标题翻译：谐波周期结构和使用它们作为滤波器和传感器的方法
公开(公告)号：WO2017033184A1
公开(公告)日：2017-03-02
申请号：PCT/IL2016/050914
申请日：2016-08-21
申请人： ABDULHALIM, Ibrahim
发明人： ABDULHALIM, Ibrahim
IPC分类号： G01N21/00 , G01N29/00
CPC分类号： G01N21/4788 , G01N21/554 , G01N21/774 , G01N21/7743
摘要： The invention relates to the field of surface waves based optical devices particularly tuneable optical filter, optical biosensors and spatial light modulators. An optical sensor and tuneable filter is disclosed based on high contrast periodic structures deposited on a substrate and using a compact reading method for low detection limit using a one dimensionally diverging quasi-monochromatic beam and a camera.
摘要翻译：本发明涉及基于表面波的光学器件，特别是可调光学滤光器，光学生物传感器和空间光调制器的领域。公开了一种光学传感器和可调谐滤波器，其基于沉积在基板上的高对比度周期性结构，并且使用一维发散准单色光束和照相机使用紧凑的读取方法来检测低检测限。

9. 发明申请

WO2022137225A1 PESTICIDE COMPOSITIONS OF LICOCHALCONE C 审中-公开
公开(公告)号：WO2022137225A1
公开(公告)日：2022-06-30
申请号：PCT/IL2021/051303
申请日：2021-11-03
申请人： METABOLIC INSIGHTS LTD.
发明人： PANIK, David , KORMAN, Ido
IPC分类号： A01N35/04 , A01N31/08 , A01N31/16 , A01P3/00 , A01P1/00 , C07C15/50 , C07C39/21 , C07C49/203 , C07C49/213 , C07C49/217 , C07C49/223 , C07C49/248
摘要： A composition comprising Licochalcone C or an agriculturally acceptable salt thereof as an active pesticidal ingredient is provided. A method for controlling, preventing, reducing or eradicating the instances of plant-pathogen infestation on a plant, plant organ, plant part, or plant propagation material is further provided, the method comprising: applying to a plant, plant part, plant organ or plant propagation material, or to soil surrounding said plant, a pesticidal effective amount of Licochalcone C or a pesticide composition comprising it, wherein said plant-pathogen is a member selected from: an order of the class Agaricomycetes; a genus of the family Pythiaceae, a genus of the family Sclerotiniaceae selected from Sclerotinia and Fusarium, and family of the order Pseudomonadales.

10. 发明申请

WO2021240507A1 METHOD FOR MANUFACTURING A COPPER-CONTAINING POLYURETHANE FOAM 审中-公开
公开(公告)号：WO2021240507A1
公开(公告)日：2021-12-02
申请号：PCT/IL2021/050598
申请日：2021-05-23
申请人： MEDCU TECHNOLOGIES LTD.
发明人： LUSTIGER, Danny , BORKOW, Gadi
IPC分类号： C08J9/00 , C08G18/00 , C08K3/015 , C08K3/08 , C08K3/22
摘要： A manufacturing method described in the present invention provides antimicrobial copper-containing polyurethane foams by embedding microparticles of metallic copper (Cu), cuprous oxide (CU2O), cupric oxide (CuO), or cuprous iodide (Cul), or combinations thereof, into polyurethane foams, wherein said microparticles are homogenously distributed throughout the formed polymeric matrix of said foam. The method combines these copper-containing microparticles, or polyurethane liquid additive containing these particles, mixed in polyol with isocyanate.

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