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    • 6. 发明申请
    • IMMUNOASSAY AND KIT FOR AN EARLY AND SIMULATANEOUS DETECTION OF BIOCHEMICAL MARKERS IN A PATIENT'S SAMPLE
    • 免疫分析和试剂盒用于早期和模拟检测患者样品中的生化标志物
    • WO2003046140A2
    • 2003-06-05
    • PCT/US2002/037861
    • 2002-11-26
    • DIAGENICS INTERNATIONAL CORPORATIONNOLLS, Franz
    • NOLLS, Franz
    • C12N
    • G01N33/6887G01N33/54393G01N33/573
    • The present invention comprises an immunochemical assay for determination of at least two antigens in a sample. The immunochemical assay comprises contacting a sample from a patient with a carrier molecule that contains at least two capture antibodies, each of which specifically binds to a binding moiety of an antigen in the sample. The assay further contains a detection antibody that specifically binds the same antigens on different binding moieties than binding moieties used by the capture antibodies. The detection agent is further attached to one or more detection probes to facilitate the detection of antigens in the sample. The immunochemical assay of the present invention is specifically designed to detect biochemical markers that are released at different time intervals in a patient's sample.
    • 本发明包括用于确定样品中至少两种抗原的免疫化学测定。 免疫化学测定包括使来自患者的样品与含有至少两种捕获抗体的载体分子接触,其中每种捕获抗体特异性结合样品中抗原的结合部分。 该测定还包含检测抗体,其特异性结合与捕获抗体所使用的结合部分不同的结合部分上的相同抗原。 检测剂进一步附着到一个或多个检测探针上以便于检测样品中的抗原。 本发明的免疫化学测定法被特别设计用于检测在患者样品中以不同时间间隔释放的生物化学标记物。