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1. 发明申请

WO2009154915A3 TISSUE ABLATION APPARATUS AND METHOD USING ULTRASONIC IMAGING 审中-公开
公开(公告)号：WO2009154915A3
公开(公告)日：2009-12-23
申请号：PCT/US2009/044406
申请日：2009-05-18
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C.
发明人： ORMSBY, Theodore, C.
IPC分类号： A61B18/18 , A61B8/00
摘要： A coaxial cable apparatus which transmits radio frequency (RF) energy for the ablation of biological tissues has inner and outer coaxial conductors extending from a proximal portion to a distal portion. An RF antenna is disposed at the distal portion of the cable and transmits RF energy for ablation of a tissue region to be treated. At least one ultrasonic transducer is also disposed at the distal portion of the cable to direct ultrasonic frequency energy to a tissue region. The ultrasonic transducer detects reflected ultrasonic signals from the tissue region and provides a signal output which varies dependent on the density of tissue over the monitored tissue region. The reflected ultrasonic signal can be monitored before, during, and after ablation treatment.

2. 发明申请

WO2003073175A2 METHOD AND SYSTEM FOR AN INTELLIGENT SUPERVISORY CONTROL SYSTEM 审中-公开
标题翻译：智能监控系统的方法与系统
公开(公告)号：WO2003073175A2
公开(公告)日：2003-09-04
申请号：PCT/US2003/006077
申请日：2003-02-26
申请人： ZYBERNETIX, INC. , PINEDA, Jaime, A. , ALLISON, Brendan, Z.
发明人： PINEDA, Jaime, A. , ALLISON, Brendan, Z.
IPC分类号： G05B
CPC分类号： G06F3/015
摘要： An intelligent supervisory control system or neuro-user interface (NUI), and method that utilize bioelectric state of mind or cognitive profile to control electronic and mechanical resources in an environment, such as in a 3-D PC or console game, a simulation or virtual environment, a cockpit, automobile, home, or surgical theatre. The interface comprises means for acquiring the brain signals of a user or subject, which are converted into a digital stream and mathematically processed to define an electrical state of the mind or cognitive profile of the user. Incorporating microprocessor-based software and storage facilities, the interface dynamically maps the cognitive profile onto multiple functions, which are adaptable for actuating microprocessor commands. In conjunction with other standard input devices such as mouse, keyboard, or joystick, the intelligent supervisory control interface of the present invention thus provides a user with the maximal degrees of freedom for the control of the resources (or electrical and mechanical devices) in the environment.
摘要翻译：智能监控系统或神经用户界面（NUI）以及利用生物电学状态或认知概况来控制环境中的电子和机械资源的智能监控系统或方法，例如在3-D PC或控制台游戏中，模拟或虚拟环境，驾驶舱，汽车，家庭或手术室。该接口包括用于获取用户或被摄体的脑信号的装置，其被转换成数字流并且被数学处理以定义用户的心理或认知轮廓的电状态。结合基于微处理器的软件和存储设备，接口将认知轮廓动态地映射到多个功能上，这些功能适用于执行微处理器命令。因此，本发明的智能监控控制接口与诸如鼠标，键盘或操纵杆的其他标准输入设备相结合，从而为用户提供了控制资源（或电气和机械设备）的最大自由度环境。

3. 发明申请

WO2005016119A2 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 审中-公开
标题翻译：基于无线电频率的导管系统及其生物组织研究方法
公开(公告)号：WO2005016119A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/024696
申请日：2004-07-30
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ("RF") generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed. The RF generator having variable output frequency is adapted to generate and communicate RF energy to the RF antenna that minimizes reflected energy from the antenna-tissue interface. In application, the RF antenna establishes line of contact with the body vessel conformable to its internal contour to prescribe the precise tissue ablation pathway despite body vessel movements. The RF antenna is steered by the steering control lines to establish its body vessel conformation. The catheter system is energized and system senses the reflected RF power relative to its output power and adjusts the frequency of the power output to effect impedance match between the transmission line of the system and the tissue ablation load.
摘要翻译：改进的基于射频的导管系统和用于消除患者体内血液中生物组织的方法包括：射频（“RF”）发生器，用于在具有RF同轴传输线的可展开导管中选择性地产生高频能量具有中空管腔，安装在导管的远端部分上的RF天线以及用于转向导管的传输线的内腔中的转向控制线，同时插入到身体容器中并用于偏转RF天线以适应需要组织消融的身体血管。具有可变输出频率的RF发生器适于产生RF通信并将RF能量传送到RF天线，其使得天线 - 组织界面的反射能量最小化。在应用中，RF天线与体内血管建立接触线，以符合其内部轮廓，以规定精确的组织消融路径，尽管身体血管运动。 RF天线由转向控制线转向以建立其身体血管构象。导管系统被通电，系统相对于其输出功率感测反射的RF功率，并且调节功率输出的频率以实现系统的传输线与组织消融负载之间的阻抗匹配。

4. 发明申请

WO2010002888A3 ANGIOPLASTY AND TISSUE ABLATION APPARATUS AND METHOD 审中-公开
公开(公告)号：WO2010002888A3
公开(公告)日：2010-01-07
申请号：PCT/US2009/049251
申请日：2009-06-30
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C. , LEUNG, George , SHEN, Gwo, Jenn
发明人： ORMSBY, Theodore, C. , LEUNG, George , SHEN, Gwo, Jenn
IPC分类号： A61B18/18 , A61M25/10
摘要： A coaxial cable apparatus which transmits radio frequency (RF) energy for the ablation of biological tissues has inner and outer coaxial conductors extending substantially the entire length of the cable from a proximal end portion to a distal end portion. An RF antenna is disposed at the distal end portion of the cable and transmits RF energy for ablation of a tissue region to be treated. An angioplasty balloon is disposed over the RF antenna and communicates with a fluid supply and extraction passageway extending through the cable to allow the balloon to be inflated for an angioplasty procedure including tissue ablation, and to be deflated after the procedure is complete.

5. 发明申请

WO2004032726A2 DISTRACTION SCREW FOR SKELETAL SURGERY AND METHOD OF USE 审中-公开
标题翻译：用于骨科手术的分离螺钉及其使用方法
公开(公告)号：WO2004032726A2
公开(公告)日：2004-04-22
申请号：PCT/US2003/032456
申请日：2003-10-14
申请人： ABDOU, M., Samy
发明人： ABDOU, M., Samy
IPC分类号： A61B
CPC分类号： A61B17/8685 , A61B17/7059 , A61B17/7082 , A61B17/8038 , A61B17/8042 , A61B17/861 , A61B17/862 , A61B17/8875 , A61B17/8877 , A61B17/8883 , A61B17/8888 , A61B2017/0256
摘要： An improved distraction bone screw and a method for its use are described. The distraction screw is comprised of an implantable distal segment and a detachably secured proximal segment. The distal segment includes a head portion and a threaded shank portion. The proximal segment is represented as an elongated body having an internal bore that extends through its length. A deployable member is disposed within the bore, which is extendible outside the internal bore to securely couple to the distal segment. As an assembly, the distraction screw is used to affix and realign bone during surgical reconstruction. Upon completion of the surgical work, the proximal segment is removed and the distal segment is left attached to the reconstructed bone. Securely affixed, the distal segment provides an additional point of fixation for the skeletal plates that are used to preserve the bony alignment while bone healing occurs. The affixed distal segment will also provide a ready mechanism for distraction screw replacement at the time of surgical revision without obligatory plate removal. Different embodiments of the proximal segment, distal segment and the rotational locking mechanisms which inhibit the rotation of one segment relative to the other during deployment were also described. In addition, in cases where the distraction screw must be placed into the bone at an inclined angle, poly-axial heads were provided so that proper skeletal plate placement can still be accomplished.
摘要翻译：描述了一种改进的牵引骨螺钉及其使用方法。牵引螺钉包括可植入的远端段和可拆卸地固定的近端段。远端段包括头部和螺纹柄部分。近端段被表示为具有延伸穿过其长度的内孔的细长体。可展开构件设置在孔内，该孔可在内孔的外部延伸以牢固地联接到远端段。作为组件，牵引螺钉用于在手术重建期间固定和重新对准骨骼。在外科手术完成后，将近端段移除，将远端段与重建的骨骼相连。安全地固定，远端段为骨骼板提供额外的固定点，用于在发生骨愈合时用于保留骨对齐。固定的远侧部分还将提供用于在手术修正时进行分心螺钉置换的准备机构，而不必强制拔除板。还描述了近端段，远端段和旋转锁定机构的不同实施例，其在展开期间阻止一个段相对于另一段的转动。此外，在牵引螺钉必须以倾斜角度放置在骨头中的情况下，设置多轴头以使得仍然可以实现适当的骨架板放置。

6. 发明申请

WO2011066445A2 RADIO FREQUENCY ABLATION SYSTEM WITH TRACKING SENSOR 审中-公开
标题翻译：具有跟踪传感器的无线电频率系统
公开(公告)号：WO2011066445A2
公开(公告)日：2011-06-03
申请号：PCT/US2010/058082
申请日：2010-11-24
申请人： MEDWAVES, INC. , ORMSBY, Theodore C. , JENN, Shen, Gwo , LEUNG, George, L.
发明人： ORMSBY, Theodore C. , JENN, Shen, Gwo , LEUNG, George, L.
IPC分类号： A61B18/18 , A61B18/14 , A61B18/12
CPC分类号： A61B18/1815 , A61B2018/00196 , A61B2018/1853 , A61B2018/1861 , A61B2034/2051
摘要： An RF ablation system has a hollow conductive coaxial cable comprising inner and outer coaxial tubular conductors, and an ablating member mounted at the distal end portion of the cable for delivery of radio frequency energy including microwaves to the target body tissue. The inner conductor has a central lumen and extends at least up to the ablating member. At least one electromagnetic tracking sensor coil with a magnetic core is located in the central lumen at the distal end portion of the cable, close to the distal tip of the cable, and connected to a signal processing unit. An electromagnetic field generator positioned in the vicinity of a patient undergoing treatment generates an electromagnetic field which induces a voltage in the sensor coil. The signal processing unit uses the induced voltage to calculate the position and orientation of the distal end portion or tip of the catheter in a patient's body.
摘要翻译： RF消融系统具有中空的导电同轴电缆，其包括内部和外部同轴管状导体，以及安装在电缆的远端部分处的消融部件，用于将包括微波的无线电频率能量传送到目标身体组织。内部导体具有中心腔并至少延伸至烧蚀构件。具有磁芯的至少一个电磁跟踪传感器线圈位于电缆的远端部分的中央腔内，靠近电缆的远端，并连接到信号处理单元。位于接受治疗的患者附近的电磁场发生器产生感应线圈中的电压的电磁场。信号处理单元使用感应电压来计算导管在患者体内的远端部分或尖端的位置和取向。

7. 发明申请

WO2010121047A3 RADIO FREQUENCY BASED ABLATION SYSTEM AND METHOD WITH DIELECTRIC TRANSFORMER 审中-公开
公开(公告)号：WO2010121047A3
公开(公告)日：2010-10-21
申请号：PCT/US2010/031266
申请日：2010-04-15
申请人： MEDWAVES, INC. , ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
发明人： ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
IPC分类号： A61B18/18 , A61B17/3205
摘要： An ablation device which transmits radio frequency (RF) energy for the ablation of biological tissues has elongate inner and outer coaxial conductors extending from a proximal portion to a distal portion. An RF antenna is disposed at the distal portion of the device and transmits RF energy for ablation of a tissue region to be treated. Reflection of energy from the tissue or the ablation point is reduced by providing multiple layers of dielectric media about the antenna, or by providing a gradual transition point from the conductors to the antenna tip, by means of a longitudinally stepped dielectric layer transformer.

8. 发明申请

WO2010121040A2 ELECTRICALLY TUNABLE TISSUE ABLATION SYSTEM AND METHOD 审中-公开
标题翻译：电动可控组织吸收系统和方法
公开(公告)号：WO2010121040A2
公开(公告)日：2010-10-21
申请号：PCT/US2010/031259
申请日：2010-04-15
申请人： MEDWAVES, INC. , ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
发明人： ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1869
摘要： An ablation system which transmits radio frequency (RF) energy for the ablation of biological tissues has a transmission line and an RF antenna disposed at the distal portion of the transmission line. An RF signal generator supplies RF energy to the proximal end of the cable for transmission to the antenna, and an electrically tunable transformer is connected between the signal generator and the antenna. The transformer is tuned based on detection of the reflected power level from the antenna so as to reduce or minimize reflected power, thereby increasing RF energy coupling between the antenna and tissue.
摘要翻译：传输用于生物组织消融的射频（RF）能量的消融系统具有设置在传输线的远端部分的传输线和RF天线。 RF信号发生器将RF能量提供给电缆的近端以传输到天线，并且电可变变压器连接在信号发生器和天线之间。基于从天线的反射功率电平的检测来调整变压器，以便减少或最小化反射功率，从而增加天线和组织之间的RF能量耦合。

9. 发明申请

WO2004062482A2 PLATING SYSTEM FOR BONE FIXATION AND SUBSIDENCE AND METHOD OF IMPLANTATION 审中-公开
标题翻译：用于骨固定和替代的植入系统和植入方法
公开(公告)号：WO2004062482A2
公开(公告)日：2004-07-29
申请号：PCT/US2004/000567
申请日：2004-01-10
申请人： ABDOU, Samy, M.
发明人： ABDOU, Samy, M.
IPC分类号： A61B
CPC分类号： A61B17/8004 , A61B17/7059 , A61B17/8605 , A61B17/869 , A61B2017/0256
摘要： A bone plating system is provided that permits maintenance of a compression force while also accommodating bony subsidence, among other features. Methods of implantation are also provided that improve alignment and placement during implantation and avoid maneuvers that weaken the vertebral bodies. A modular distraction screw is placed during the initial stages of surgery when all relevant landmarks are still intact. After completion of the surgical bone work, a proximal end of the distraction screw is detached, leaving a protruding distal segment implanted in the centerline of the vertebral bodies above and below the newly fused disc space. A bone plate is guided into proper position relative to the upper and lower vertebra by attaching the bone plate to the protruding distal segments. The distal segments of the distraction screws are tightened onto the plate and the plate is held stationary while bone screws are placed. The bone plating system is also extendable, allowing additional bone plates to be placed and coupled with existing plate components to create a multi-level plating system. Additional bone plates may be placed contemporaneously or during a subsequent surgical procedure.
摘要翻译：提供了一种允许维持压缩力同时还容纳骨沉降的骨电镀系统，以及其他特征。还提供了植入方法，改善植入过程中的对准和放置，并避免削弱椎体的机动。在手术的初始阶段放置模块化牵引螺钉，当所有相关的地标仍然完好无损的时候。在手术骨工作完成后，分离螺钉的近端被分离，留下突出的远侧段植入在新融合的椎间盘空间上方和下方的椎体的中心线。骨板通过将骨板连接到突出的远端段而被引导到相对于上，下椎骨的适当位置。牵引螺钉的远端段被紧固在板上，并且在放置骨螺钉的同时将板保持静止。骨电镀系统也是可扩展的，允许额外的骨板放置并与现有的板组件结合以产生多层电镀系统。另外的骨板可以同时放置或在随后的手术过程中放置。

10. 发明申请

WO2003073175A3 METHOD AND SYSTEM FOR AN INTELLIGENT SUPERVISORY CONTROL SYSTEM 审中-公开
公开(公告)号：WO2003073175A3
公开(公告)日：2003-09-04
申请号：PCT/US2003/006077
申请日：2003-02-26
申请人： ZYBERNETIX, INC. , PINEDA, Jaime, A. , ALLISON, Brendan, Z.
发明人： PINEDA, Jaime, A. , ALLISON, Brendan, Z.
IPC分类号： G09G5/00
摘要： An intelligent supervisory control system or neuro-user interface (NUl), and method that utilize bioelectric state of mind or cognitive profile to control electronic and mechanical resources in an environment, such as in a 3-D PC or console game, a simulation or virtual environment, a cockpit, automobile, home, or surgical theatre The interface comprises means for acquiring the brain signals of a user or subject, converted into a digital stream and mathematically processed to define an electrical state of the mind or cognitive profile of the user Incorporating microprocessor-based software and storage, the interface dynamically maps the cognitive profile onto multiple functions, which are adaptable for actuating microprocessor commands, conjunction with other standard input devices such as mouse, keyboard, or joystick, the intelligent supervisory control interface of the present invention thus provides a user with the maximal degrees of freedom for the control of the resources in the environment.

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