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1. 发明申请

WO2009140249A1 SYSTEM AND METHODS FOR FOOD PROCESSING 审中-公开
标题翻译：食品加工系统与方法
公开(公告)号：WO2009140249A1
公开(公告)日：2009-11-19
申请号：PCT/US2009/043571
申请日：2009-05-12
申请人： WAL-MART STORES, INC. , GARCIA, Jorge
发明人： GARCIA, Jorge
IPC分类号： B01F7/16
CPC分类号： A47J43/0716 , A47J36/32
摘要： Various embodiments are directed to methods of operating a food processing device. The food processing device may comprise a blade configured to rotate about a vertically oriented axis. The methods may comprise performing a plurality of rotation cycles. Each rotation cycle may comprise a first period during which the blade is rotated at a first rotation speed and a second period during which the blade is rotated at a second rotation speed. The first rotation speed may increase between successive rotation cycles, while the second rotation speed may be constant across the plurality of rotation cycles. Also, all values of the first rotation speed may be greater than the second rotation speed.
摘要翻译：各种实施例涉及操作食品加工装置的方法。食品加工装置可以包括构造成围绕垂直取向的轴线旋转的叶片。该方法可以包括执行多个旋转周期。每个旋转周期可以包括第一时段，在该第一周期期间，叶片以第一转速旋转，在第二时段期间叶片以第二转速旋转。第一旋转速度可以在连续旋转周期之间增加，而第二旋转速度在多个旋转周期中可以是恒定的。而且，第一转速的所有值都可以大于第二转速。

2. 发明申请

WO2017100437A1 REACTION SEQUENCE FOR THE SYNTHESIS OF NOOTKATONE, DIHYDRONOOTKATONE, AND TETRAHYDRONOOTKATONE 审中-公开
标题翻译：用于合成诺酮，二氢乌龙酮和四氢稻酮的反应顺序
公开(公告)号：WO2017100437A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/065598
申请日：2016-12-08
申请人： BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
发明人： LAINE, Roger
IPC分类号： A61K31/12 , A61K31/35 , A61K31/122 , C07C45/00 , C07C45/27 , C07C45/40
CPC分类号： A61K31/122 , C07C29/40 , C07C45/40 , C07C45/512 , C07C45/66 , C07C45/68 , C07C45/74 , C07C2602/28 , C07C2602/42 , C07C49/433 , C07C49/653 , C07C35/28 , C07C49/693
摘要： An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (−)-β-Pinene, is on the GRAS list (generally recognized as safe).
摘要翻译：利用臭氧分解公开了廉价的立体选择性合成方法，其用于诺卡酮，四氢卡托酮及其衍生物。合成中使用的原料价格低廉，反应在商业上是可行的并且适合于扩大规模。主要原料（ - ） - β-蒎烯在GRAS清单上（通常被认为是安全的）。

3. 发明申请

WO2007127295A2 CALCIUM PHOSPHATE POLYMER COMPOSITE AND METHOD 审中-公开
标题翻译：磷酸钙聚合物复合材料和方法
公开(公告)号：WO2007127295A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/010114
申请日：2007-04-25
申请人： TELEFLEX MEDICAL INCORPORATED , WEI, Mei , OLSON, James R. , SHAW, Montgomery T.
发明人： WEI, Mei , OLSON, James R. , SHAW, Montgomery T.
IPC分类号： A61F2/28
CPC分类号： A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2/30965 , A61F2/468 , A61F2002/2817 , A61F2002/30032 , A61F2002/30062 , A61F2002/30224 , A61F2002/30235 , A61F2002/30293 , A61F2002/30677 , A61F2002/30914 , A61F2002/30957 , A61F2210/0004 , A61F2230/0069 , A61F2230/0091 , A61F2250/003 , A61F2310/00293 , A61F2310/00365 , A61F2310/00796 , A61L27/20 , A61L27/425 , A61L2430/02 , C08L5/08
摘要： A bone-repair composite includes a core and a sheath. The core is a first primary unit including a combination of a first set of yarns coated with an apatite calcium phosphate mineral layer. The first set of yarns being made from a first group of one ore more polymers. The sheath is a second primary unit which can be either polymer or including a combination of a second set of yarns or one or more polymer coatings. The second set of yarns being made from a second group of one or more polymers, wherein the composite is made by covering the core with the sheath, and the composite is compression molded to allow the sheath to bond to the core. The bone-repair composite has a bending modulus comparable to that of a mammalian bone, such that the ratio of the core to the sheath is provided to maximize the mechanical strength of the bone-repair composite to mimic the mammalian bone. Furthermore, a method for making a bone repair synthetic composite comprising the steps of: treating a polymer fiber with a surface modifying chemical, wherein the polymer fiber is a natural polymer or a synthetic polymer; coating the polymer fiber with a mineral layer; and forming a primary structure with at least one of the mineral coated polymers or at least one of the polymer fibers.
摘要翻译：骨修复复合物包括芯和护套。芯是第一主要单元，其包括涂覆有磷灰石磷酸钙矿物层的第一组纱线的组合。第一组纱线由第一组一种或多种聚合物制成。鞘是第二主要单元，其可以是聚合物或包括第二组纱线或一种或多种聚合物涂层的组合。第二组纱线由第二组一种或多种聚合物制成，其中复合材料通过用护套覆盖芯体制成，并且复合材料被压缩模制以允许护套粘合到芯体上。骨修复复合物具有与哺乳动物骨的弯曲模量相当的弯曲模量，使得提供芯与护套的比例以使骨修复复合物的机械强度最大化以模拟哺乳动物骨骼。此外，一种骨修复合成复合材料的制造方法，其特征在于，包括以下步骤：用表面改性化学品处理聚合物纤维，其中聚合物纤维是天然聚合物或合成聚合物; 用矿物层涂覆聚合物纤维; 以及用至少一种矿物涂层聚合物或至少一种聚合物纤维形成一次结构。

4. 发明申请

WO2016065204A1 BLOOD BIOMARKERS FOR APPENDICITIS AND DIAGNOSTICS METHODS USING BIOMARKERS 审中-公开
标题翻译：血液生物标记用于生物标志物的附录和诊断方法
公开(公告)号：WO2016065204A1
公开(公告)日：2016-04-28
申请号：PCT/US2015/057009
申请日：2015-10-22
申请人： THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION
发明人： CHAWLA, Lakhmir S. , MCCAFFREY, Timothy A.
IPC分类号： C12Q1/68 , G01N33/49
CPC分类号： C12Q1/6883 , C12Q2600/158 , G01N33/566 , G01N33/6893 , G01N33/84 , G01N2500/04 , G01N2800/06 , G01N2800/56
摘要： The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising obtaining a biological sample from said subject; detecting RNA expression levels of at least three or more biomarkers in the biological sample and comparing the expression levels of said at least three or more biomarkers to a control sample wherein an increase or decrease in the level of expression of said at least three or more biomarkers as compared to the control sample is indicative of appendicitis.
摘要翻译：本发明涉及用于诊断和/或治疗受试者阑尾炎的方法和试剂盒，包括从所述受试者获得生物样品; 检测生物样品中至少三种或更多种生物标志物的RNA表达水平，并将所述至少三种或更多种生物标志物的表达水平与对照样品进行比较，其中所述至少三种或更多种生物标志物的表达水平的增加或减少与对照样品相比，阑尾炎是指示性的。

5. 发明申请

WO2014210543A1 NANOPARTICULATE COMPOSITIONS AND FORMULATIONS OF PIPERAZINE COMPOUNDS 审中-公开
标题翻译：纳米颗粒组合物和哌嗪化合物的制剂
公开(公告)号：WO2014210543A1
公开(公告)日：2014-12-31
申请号：PCT/US2014/044714
申请日：2014-06-27
申请人： REXAHN PHARMACEUTICALS, INC.
发明人： LEE, Young Bok , AHN, Chang-Ho , KIM, Deog Joong
IPC分类号： A61K9/14 , A61K31/498 , A61P35/00
CPC分类号： A61K31/498 , A61K9/14 , A61K9/141 , A61K9/145 , A61K9/146 , A61K9/51
摘要： The present invention relates to storage stable nanoparticulate compositions of piperazine compounds. The pharmaceutical compositions comprising the nanoparticulate compositions that are useful for the treatment and prevention of proliferative diseases including cancer are also described.
摘要翻译：本发明涉及哌嗪化合物的储存稳定的纳米颗粒组合物。还描述了包含可用于治疗和预防包括癌症在内的增殖性疾病的纳米颗粒组合物的药物组合物。

6. 发明申请

WO2008118943A1 ELECTROSPUN APATITE/POLYMER NANO-COMPOSITE SCAFFOLDS 审中-公开
标题翻译：电极APATITE /聚合物纳米复合材料
公开(公告)号：WO2008118943A1
公开(公告)日：2008-10-02
申请号：PCT/US2008/058234
申请日：2008-03-26
申请人： WEI, Mei , PENG, Fei , XU, Zhi-Kang
发明人： WEI, Mei , PENG, Fei , XU, Zhi-Kang
IPC分类号： B32B5/00 , B82B1/00
CPC分类号： A61F2/02 , A61L27/46 , A61L27/48 , Y10T428/24124 , Y10T428/2924 , Y10T428/2927 , C08L67/04
摘要： An artificial bone composite structure is provided. This structure includes a fibrous matrix that itself includes a plurality of fibers. Also, the structure includes a plurality of hydroxyapatite (HA) particles. These particles are dispersed within the fibrous matrix. Also, the HA particles have controlled size and aspect ratios and are aligned along long axes of the fibers. In some instances, the fibers include poly-(L-lactic acid) (PLLA).
摘要翻译：提供人造骨复合结构。该结构包括本身包括多根纤维的纤维基质。此外，该结构包括多个羟基磷灰石（HA）颗粒。这些颗粒分散在纤维基质内。此外，HA颗粒具有受控的尺寸和纵横比，并且沿着纤维的长轴对准。在一些情况下，纤维包括聚-L-乳酸（PLLA）。

7. 发明申请

WO2017059057A1 NANO-ADHESIVE AND SURFACE PRIMER COMPOUND AND USE THEREOF 审中-公开
标题翻译：纳米粘合剂和表面化合物及其用途
公开(公告)号：WO2017059057A1
公开(公告)日：2017-04-06
申请号：PCT/US2016/054418
申请日：2016-09-29
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： AHN, B. Kollbe , WAITE, J. Herbert
IPC分类号： C09J133/06 , C09J5/00 , A61L24/04
CPC分类号： C09J4/00 , A61L24/046 , A61L2400/12 , C08L67/04
摘要： A compound for self-assembly onto a mineral and/or metal oxides substrate, the compound comprising a catechol group attached to an end group through a spacer group. The compound include a structure of Formula (I): Formula (I)
摘要翻译：用于自组装到矿物和/或金属氧化物底物上的化合物，所述化合物包含通过间隔基团连接到端基上的儿茶酚基团。化合物包括式（I）的结构：式（I）

8. 发明申请

WO2016201146A1 FLUOROCYCLOPENTENYLCYTOSINE USES AND PROCESSES OF PREPARATION 审中-公开
标题翻译：氟代环戊烯酸的使用和制备方法
公开(公告)号：WO2016201146A1
公开(公告)日：2016-12-15
申请号：PCT/US2016/036768
申请日：2016-06-09
申请人： REXAHN PHARMACEUTICALS, INC.
发明人： LEE, Young Bok , KIM, Deog Joong , PETERS, Godefridus J. , SARKISJAN, Dzjemma , MAZHARI, Reza
IPC分类号： A61K9/48 , A61K31/513 , A61K39/395 , C07D239/47 , A61P35/00
CPC分类号： A61K31/513 , A61K9/0053 , A61K9/20 , A61K9/2004 , A61K9/48 , A61K9/4841 , A61K39/00 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07D239/47 , C07K16/2818 , C07K16/2827 , C07K2317/76 , C12Y207/01048 , G01N33/57496 , G01N2333/91215 , G01N2800/52 , A61K2300/00
摘要： The disclosed subject matter provides methods using and kits comprising a compound of formula (I): Formula (I) or a hydrate, a solvate, or a pharmaceutically acceptable salt thereof. The disclosed subject matter further provides a method of treating one or more symptoms of cancer comprising administering to a subject in need thereof a compound of formula (I) and a process for preparing such.
摘要翻译：所公开的主题提供了包含式（I）化合物：式（I）或其水合物，溶剂化物或其药学上可接受的盐的方法和试剂盒。所公开的主题还提供了治疗癌症的一种或多种症状的方法，包括向有需要的受试者施用式（I）化合物及其制备方法。

9. 发明申请

WO2016154624A1 FLUORINATED DYE COMPOUNDS FOR ORGANIC SOLAR CELLS 审中-公开
标题翻译：用于有机太阳能电池的荧光染料化合物
公开(公告)号：WO2016154624A1
公开(公告)日：2016-09-29
申请号：PCT/US2016/024535
申请日：2016-03-28
申请人： NEXT ENERGY TECHNOLOGIES, INC.
发明人： BRAUN, Max Josef , NAUERT, Stefanie , GUTMANN, Sebastian , WOOD, Thomas Kuchurean , SMITH, Braden Gmelin , CAPUTO, Bruno John Anthony , GARCIA, Andres , HARRIS, Rachel Ann , PATEL, Priyam , LLOYD, Matthew Thomas , HOVEN, Corey Vernon , TAMAYO, Arnold Bernarte
IPC分类号： H01L51/54
CPC分类号： H01L51/0094 , C07F7/0816 , C09B57/00 , C09K11/06 , C09K2211/1055 , C09K2211/1066 , C09K2211/1092 , H01L51/0047 , H01L51/0068 , H01L51/0071 , H01L51/008 , H01L51/424 , H01L51/4253 , Y02E10/549
摘要： Electronic or optoelectronic device comprising a first electrode, a second electro, and an active layer arranged between and in electrical connection with the first and the second electrode. The active layer comprises at least one dye compound, which comprises small-molecule organic solar cells.
摘要翻译：电子或光电子器件包括布置在第一和第二电极之间并与之电连接的第一电极，第二电极和有源层。活性层包含至少一种包含小分子有机太阳能电池的染料化合物。

10. 发明申请

WO2010120764A1 TREATMENT METHOD FOR TREATMENT OF ERECTILE DYSFUNCTION AND PREMATURE EJACULATION 审中-公开
标题翻译：治疗溃疡性功能障碍和预防手术的治疗方法
公开(公告)号：WO2010120764A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030873
申请日：2010-04-13
申请人： MODULAR PROPERTIES, LTD. , SALLIS, Ramsey , HA, Quoc Huan
发明人： SALLIS, Ramsey , HA, Quoc Huan
IPC分类号： A61P15/00
CPC分类号： A61K31/417 , A61K31/46 , A61K31/472 , A61K31/557 , A61K2300/00
摘要： A method for a same visit treatment for erectile dysfunction and premature ejaculation. The method includes: performing a diagnostic on the patient using physical conditions of the patient; determining a diagnostic group of the patient, wherein each diagnostic group has corresponding conditions to the physical conditions of the patient; identifying an age group of the patient; selecting a first test dose of a pharmaceutical composition, which corresponds to the age group and the diagnostic group of the patient, wherein the pharmaceutical composition is a solution with PGE1, papaverine, phentolamine, and atropine; administrating the first test dose to the patient; observing the physical conditions of the patient after the administration of the first test dose; determining a result group of the patient after observing the physical conditions of the patient; and prescribing a same visit dosage for the patient based on the result group.
摘要翻译：一种用于勃起功能障碍和早泄的相同观察治疗方法。该方法包括：使用患者的身体状况对患者进行诊断; 确定患者的诊断组，其中每个诊断组具有与患者的身体状况相对应的条件; 识别患者的年龄组; 选择对应于患者的年龄组和诊断组的药物组合物的第一测试剂量，其中所述药物组合物是与PGE1，罂粟碱，酚妥拉明和阿托品的溶液; 向患者施用第一试验剂量; 在施用第一次测试剂量后观察患者的身体状况; 在观察患者的身体状况之后确定患者的结果组; 并根据结果组为患者开具相同的访视剂量。

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