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1. 发明申请

WO2023084024A1 SELECTIVE PERFUSION DEVICE AND METHOD 审中-公开
公开(公告)号：WO2023084024A1
公开(公告)日：2023-05-19
申请号：PCT/EP2022/081622
申请日：2022-11-11
申请人： VESTLANDETS INNOVASJONSSELSKAP AS (VIS)
发明人： TUSETH, Vegard , HALVORSEN LØLAND, Kjetil
IPC分类号： A61M1/16 , A61M1/36
摘要： The present invention relates to a system for the selective treatment of one or more organs, said system comprising a first catheter comprising a means for occluding a first lumen downstream of said organ(s); a second catheter comprise a means for occluding a second lumen upstream of said organ(s); an extracorporeal device configured to deliver fluid through the first catheter and to receive fluid through the second catheter, and comprising means for processing the fluid. The present invention also relates to a method for the selective treatment of one or more organs.

2. 发明申请

WO2023067006A1 PATIENT POSITIONING SYSTEM FOR RADIATION EMISSION TREATMENT AND/OR DIAGNOSIS EQUIPMENT 审中-公开
公开(公告)号：WO2023067006A1
公开(公告)日：2023-04-27
申请号：PCT/EP2022/079109
申请日：2022-10-19
申请人： INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA (IDIBGI) , INSTIUT CATALÀ D'ONCOLOGIA (ICO) , COMPOXI SL
发明人： ROMERA MARTÍNEZ, Ingrid , MUÑOZ MONTPLET, Carles , JURADO BRUGGEMAN, Diego , MARRUECOS QUEROL, Jordi , BOU SÁNCHEZ, Salvador , GRÈBOL CANAL, Roger , GASCONS TARRÉS, Marc , VICENS CUYÀS, Pep
IPC分类号： A61N5/10 , A61B90/00 , A61B5/113 , A61B5/00
摘要： The invention refers to a system for positioning patients during treatment and/ or diagnosis processes, preferably for radiotherapy treatments, in which patients must be irradiated in a deep inspiration breath hold position. The system is synchronized with an electron accelerator, in a way that radiation is applied on a patient only if the patient is in a proper deep inspiration hold position. The electron accelerator is controlled by the contact sensor (12), preferably a pressure sensor, so that radiation can be applied on a patient only when a correct pressure is exerted on the contact sensor (12). In addition, while the contact sensor is pressed correctly, signalling means are activated, to inform a patient and an accelerator operator, that the patient is in a proper deep inspiration hold position. The invention achieves high reproducibility in patient positioning while irradiating patients in deep inspiration breath hold position, and avoiding undesired radiation to other vital organs such as the heart.

3. 发明申请

WO2023061723A1 HYDROXYPHENYL-ETHYNYL-PHENOL DERIVATIVES AS AR (ANDROGEN RECEPTOR) TRANSCRIPTIONAL ACTIVITY MODULATORS FOR USE IN THE TREATMENT OF I.A. PROSTATE CANCER 审中-公开
公开(公告)号：WO2023061723A1
公开(公告)日：2023-04-20
申请号：PCT/EP2022/076442
申请日：2022-09-22
申请人： FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) , UNIVERSITAT DE BARCELONA , INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS , PROVINCIAL HEALTH SERVICES AUTHORITY
发明人： SALVATELLA GIRALT, Xavier , RIERA ESCALÉ, Antoni , FRIGOLÉ VIVAS, Marta , SÁNCHEZ ZARZALEJO, Carolina , RUFFONI, Alessandro , VERDAGUER ESPAULELLA, Francesc Xavier , SADAR, Marianne Dorothy , BANUELOS, Carmen Adriana , MAWJI, Nasrin
IPC分类号： A61K31/09 , A61K31/519 , A61P5/26 , A61P5/28 , A61P35/00
摘要： The present invention relates to compounds of formula (I) and their use for modulating the transcriptional activity of the androgen receptor and its splice variants for treating various indications including prostate cancer

4. 发明申请

WO2023046905A1 GRATE PLATE FOR A PULP LIFTER OF A GRINDING MILL 审中-公开
公开(公告)号：WO2023046905A1
公开(公告)日：2023-03-30
申请号：PCT/EP2022/076531
申请日：2022-09-23
申请人： METSO OUTOTEC FINLAND OY
发明人： VYORAL, Jakub
IPC分类号： B02C17/18 , B02C17/22
摘要： A grate plate is provided for use with a pulp lifter at a discharge end of a grinding mill. The grate plate has an outer edge, an inner edge, a leading side edge and a trailing side edge. The leading side edge and the trailing side edge have complementary shapes so that a series of grate plates can be mounted to the pulp lifter in a circular or annular array, with the leading side edge of each grate plate being adjacent the trailing side edge of an adjacent grate plate in the array. The grate plate comprises openings for passing through ground material particles of a predetermined size or smaller from the interior of the drum towards the pulp lifter. The grate plate further comprises, on a surface configured to face the interior of the cylindrical drum, one or more sections of lifter bars arranged so that the lifter bar sections on a number of adjacent grate plates complement each other to form lifter bars, wherein the lifter bar sections are shaped so that at least portions of the resulting lifter bars are inclined or curved in a first circumferential direction of the circular or annular array relative to a radial line of the array intersecting the respective lifter bar or lifter bar portion. At least portions of the complementary leading and trailing side edges of the grate plate are inclined or curved in a second circumferential direction of the array relative to a radial line of the array running through the point of intersection of the respective side edge with the outer edge. The second circumferential direction is opposite the first circumferential direction.

5. 发明申请

WO2023046830A1 CONSUMABLE RECOGNITION BASED ON FRICTION SOUND OF EMBOSSED FEATURES 审中-公开
公开(公告)号：WO2023046830A1
公开(公告)日：2023-03-30
申请号：PCT/EP2022/076367
申请日：2022-09-22
申请人： JT INTERNATIONAL SA
发明人： BRUNA, Matteo
IPC分类号： A24D1/02 , A24D1/20 , A24F40/51 , A24F40/53
摘要： Provided is an aerosol generation device (1), comprising an outer body (10); an opening (11) accessible on the outer body (10) and configured to receive a consumable article (2), wherein the opening (11) is configured to generate a friction sound when a consumable article (2) including embossed features (21) on its wrapper (20), the embossed features (21) preferably containing information about the consumable article (2), slides on the opening into the aerosol generation device; a sensor (12) configured to detect the friction sound; and a controller (13) configured to analyze the friction sound and identify the consumable article (2) based on the friction sound. Provided is further a consumable article (2) for an aerosol device (1), wherein the consumable article (2) is configured to be slid into an opening (11) of an aerosol generation device (1), and the consumable article (2) preferably includes embossed features (21) on its wrapper (20) and the embossed features (21) contain information about the consumable article (2). Provided is furthermore a method (preferably a computer-implemented method) executed by an aerosol generation device of identifying a consumable article inserted into the aerosol generation device, the method comprising the steps of: detecting a friction sound generated when the consumable article including embossed features on its wrapper, the embossed features preferably containing information about the consumable article, is slid on the opening into the aerosol generation device; analyzing the friction sound; and identifying the consumable article based on the friction sound, as well as a corresponding computer program.

6. 发明申请

WO2023041787A1 TAUCHSONDE MIT VARIABLER PFADLÄNGE 审中-公开
公开(公告)号：WO2023041787A1
公开(公告)日：2023-03-23
申请号：PCT/EP2022/075984
申请日：2022-09-19
申请人： IMPLEN GMBH
发明人： SAHIRI, Thomas
IPC分类号： G01N21/85 , G01N21/8507
摘要： Eine Tauchsonde (1) zur quantitativen und/oder qualitativen Analyse eines Fluids (F), z.B. einer Flüssigkeit oder eines Gases, mithilfe von Licht, das entlang eines Lichtpfads (L) durch das Fluid (F) hindurchgeführt wird, umfasst einen Messkopf (10), der zum Eintauchen in das Fluid geeignet ist, mit einem Eingangslichtleiter (14) für das zum Fluid (F) geführte Licht, der mit einer Lichtquelle verbindbar ist, und einem Ausgangslichtleiter (15) für das aus dem Fluid (F) geführte Licht, der mit einem Detektor verbindbar ist, einem ersten und zweiten optischen Fenster, deren einander zugewandte Flächen mit dem Fluid in Kontakt stehen, und mindestens einer Lichtumlenkeinrichtung (17, 18), die im Lichtpfad des aus dem Eingangslichtleiter (14) austretenden bzw. in den Ausgangslichtleiter (15) eintretenden Lichts angeordnet ist und das aus dem Eingangslichtleiter (14) kommende Licht durch das erste optische Fenster in das Fluid bzw. das aus dem Fluid kommende Licht zum Ausgangslichtleiter (15) umlenkt. Die Tauchsonde ist dadurch gekennzeichnet, dass das erste und zweite optische Fenster (20, 21) zueinander keilförmig angeordnet sind und ihre zum Keilinneren weisenden Oberflächen (20a, 21a) dem zu analysierenden Fluid (F) zugewandt sind, wobei die mindestens eine Lichtumlenkeinrichtung (17, 18) und die optischen Fenster (20, 21) relativ zueinander im Wesentlichen in Richtung der Keilöffnung hin- und her beweglich sind.

7. 发明申请

WO2023041432A1 3-PHENOXYAZETIDIN-1-YL-HETEROARYL PYRROLIDINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT 审中-公开
公开(公告)号：WO2023041432A1
公开(公告)日：2023-03-23
申请号：PCT/EP2022/075107
申请日：2022-09-09
申请人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH , ARENA PHARMACEUTICALS, INC.
发明人： GERLACH, Kai , BERTA, Daniela Gavina , FERRARA, Marco , GUTSCHE, Kirsten , MUELLER-VIEIRA, Ursula , HOBSON, Scott , RUNGE, Frank , SEMPLE, Graeme , VINTONYAK, Viktor , XIONG, Yifeng
IPC分类号： C07D403/14 , C07D417/14 , A61K31/501 , A61P25/00
摘要： The invention relates to (3)-phenoxyazetidin-(1)-yl-heteroaryl pyrrolidine derivatives of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the (3)-phenoxyazetidin-(1)-yl-heteroaryl pyrrolidine derivatives of general formula (I) for use as a medicament, pharmaceutical compositions comprising at least a compound of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

8. 发明申请

WO2023031184A1 COMPUTERIMPLEMENTIERTES VERFAHREN ZUM DATENAUSTAUSCH ZWISCHEN EINER TANKSTELLE UND EINEM CLIENT, STEUERUNG ZUM STEUERN DER WASSERSTOFF-HERSTELLUNG UND/ODER WASSERSTOFF-AUFBEREITUNG, SYSTEM ZUM STEUERN DER WASSERSTOFF-HERSTELLUNG UND/ODER WASSERSTOFF-AUFBEREITUNG SOWIE COMPUTERPROGRAMM 审中-公开
公开(公告)号：WO2023031184A1
公开(公告)日：2023-03-09
申请号：PCT/EP2022/074059
申请日：2022-08-30
申请人： ARGO GMBH
发明人： ANDREAS, Jan
IPC分类号： G06Q10/02 , G06Q30/02 , G06Q50/06 , F17C5/00
摘要： Die vorliegende Erfindung betrifft ein computerimplementiertes Verfahren zum Datenaustausch zwischen zumindest einer Tankstelle (201, 202) und einem Client (301, 311), wobei das Verfahren umfasst: Übermittlung einer Betankungsanfrage vom Client (301, 311) an die zumindest eine Tankstelle (201, 202) über eine drahtlose Datenübermittlung (320), Empfang von zumindest zwei Betankungsvorschlägen von der zumindest einen Tankstelle (201, 202) für die Betankungsanfrage des Clients (301, 311) über die drahtlose Datenübermittlung, wobei sich die zumindest zwei übermittelten Betankungsvorschläge zumindest in einem Vorschlag-Betankungsparameter (αVorschlag) voneinander unterscheiden, ausgewählt aus der Gruppe: Betankungsuhrzeit, Betankungsdauer, maximale Befüllmenge, maximale Befüllgeschwindigkeit (l/s), notwendiger Energieaufwand für die Betankung seitens der Tankstelle, Preis des Wasserstoffs, Wartezeit bis zur Betankung, verwendete Energieart für die Erzeugung des zu betankenden Wasserstoffs, CO2 Zertifikat, UmweltZertifikat. Ferner betrifft die vorliegende Erfindung ein computerimplementiertes Verfahren zur Steuerung und/oder Regelung eines Betankungsvorgangs eines Fahrzeugs, ein computer-implementiertes Verfahren zum Erfassen eines Client-Verbrauchsmusters und/oder eines Client-Betankungsmusters, ein computerimplementiertes Verfahren zum Steuern der Wasserstoff-Herstellung und/oder Wasserstoff-Aufbereitung zur Betankung von zumindest einem Fahrzeug, eine Steuerung, ein System sowie einen Remote Server. Des Weiteren betrifft die vorliegende Erfindung ein Computerprogramm sowie ein computerlesbares Speichermedium.

9. 发明申请

WO2023030853A1 CONTROL UNIT FOR AN INHALATION DEVICE AND METHOD PERFORMED BY A CONTROL UNIT FOR AN INHALATION DEVICE 审中-公开
公开(公告)号：WO2023030853A1
公开(公告)日：2023-03-09
申请号：PCT/EP2022/072544
申请日：2022-08-11
申请人： JT INTERNATIONAL SA
发明人： DODD, Simon , GIUSTI, Domenico , GULLI, Gianluca , MOTT, James Alan , BADAL, Ari
IPC分类号： A24F40/50 , A24F40/53 , A24F40/57 , A24F40/05 , A61M15/02 , B41J2/045
摘要： A control unit for an inhalation device with at least one liquid jet device for producing drops of a liquid on demand, the control unit being configured to: control supply of power to one or more heating elements of the liquid jet device based on a pulse train having pulses defined by a voltage and a pulse width; monitor a value indicative of a fluid temperature of the liquid jet device, and reduce the power supplied to the one or more heating elements of the liquid jet device when the monitored value exceeds a first threshold value.

10. 发明申请

WO2023017025A1 INHALATION DEVICE AND METHOD OF MANUFACTURING AN INHALATION DEVICE 审中-公开
公开(公告)号：WO2023017025A1
公开(公告)日：2023-02-16
申请号：PCT/EP2022/072332
申请日：2022-08-09
申请人： JT INTERNATIONAL SA
发明人： YAMAGUCHI, Akira
IPC分类号： A24F40/40 , A24F40/50 , A24F40/70 , A61M11/04 , A61M15/06 , H01H13/02 , H01H13/04 , H01H13/86
摘要： An inhalation device has a housing (10) at least partially made of a hard material and at least one button (12) provided in an opening of the housing (10) and at least partially made of a material substantially as hard as that of the housing (10) or harder, wherein the button (12) is attached to the housing (10) by means of an elastic material (14) on the inside of the housing (10). A method of producing an inhalation device includes the steps of providing a housing (10) at least partially made of a hard material and providing at least one button (12) at least partially made of a material substantially as hard as that of the housing (10) or harder and attaching at least one button (12) in an opening of the housing (10) by means of an elastic material (14) attached to the inside of the housing (10).

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