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1. 发明申请

WO2007106342A2 CLIP DEVICE AND PROTECTIVE CAP, AND METHODS OF USING THE PROTECTIVE CAP AND CLIP DEVICE WITH AN ENDOSCOPE FOR GRASPING TISSUE ENDOSCOPICALLY 审中-公开
标题翻译：夹具装置和保护帽，以及使用保护帽和夹子装置与内镜下用于组织内固定的方法
公开(公告)号：WO2007106342A2
公开(公告)日：2007-09-20
申请号：PCT/US2007/005653
申请日：2007-03-05
申请人： WILSON-COOK MEDICAL INC. , SOETIKNO, Roy, M. , SURTI, Vihar, C.
发明人： SOETIKNO, Roy, M. , SURTI, Vihar, C.
IPC分类号： A61B17/122 , A61B17/128
CPC分类号： A61B17/1285 , A61B1/012 , A61B17/122 , A61B17/1227 , A61B2017/308
摘要： A clip device delivery apparatus 10, 110 for hemostasis has an introducer tube 40, 112, such as an endoscope or sheath 130, 140, having a distal end portion 65, 190’, 152 and working channel 74, 188, 148 receiving an operating wire 114 detachably securing a clip device 111 comprising tissue engaging arms 127 and a sliding ring 132 for closing the arms. A protective cap 210 having a tube mounting section 220 and a distal section 230 having a receiving chamber 232 define a passageway 240 therebetween, the mounting section being mounted to the introducer tube distal end portion and the distal section receiving tissue and clip arms to close about tissue. The operating wire and clip device are inserted within the working channel. Methods of grasping tissue are provided using the introducer tube introduced endoscopically into a patient, tissue suctioned and clip arms deployed into tissue receiving chamber, sliding ring moved distally to close the clip arms about the tissue, and the clip detached from the operating wire.
摘要翻译：用于止血的夹具装置输送装置10,110具有导引管40,112，诸如内窥镜或护套130,140，其具有远端部分65,190'，152和工作通道74,188,148，其接收操作电线114可拆卸地固定包括组织接合臂127的夹具装置111和用于闭合臂的滑动环132。具有管安装部分220的保护盖210和具有接收室232的远端部分230在其间限定通道240，安装部分安装到导引管远端部分，远端部分接收组织和夹臂以关闭组织。工作线和夹子装置插入工作通道内。使用将内窥镜导入患者的导引管，组织抽吸和夹持臂部署到组织接收室中的方法来提供抓紧组织的方法，滑动环向远侧移动以围绕组织闭合夹持臂，并且夹子与操作线分离。

2. 发明申请

WO2007064590A1 OVER THE ENDOSCOPE INTRODUCER FOR STENTS 审中-公开
标题翻译：在STENTS内窥镜介绍
公开(公告)号：WO2007064590A1
公开(公告)日：2007-06-07
申请号：PCT/US2006/045422
申请日：2006-11-27
申请人： WILSON-COOK MEDICAL INC. , KENNEDY, Kenneth, C. II , SKERVIN, Gregory, J.
发明人： KENNEDY, Kenneth, C. II , SKERVIN, Gregory, J.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/044 , A61F2002/9517 , A61F2002/9665
摘要： Over-the-scope stent introducers (10, 110) for detachably engaging at least a portion of the outside of an endoscope insert and for delivering a stent are provided. Embodiments include an inner member (20, 120) defining a channel. The inner member includes an outer surface (36, 136) , inner endoscope engaging surface (34, 134) , and stent abutting restraint (38, 138) disposed at the first end portion (22, 122) . Embodiments also include an outer member (50, 150) having a distal section (52, 152) having an opening (58, 158) and proximal section (54, 154) having an opening (60, 160) defining a passageway (62, 162) therebetween that is sized to slideably receive at least a portion (42, 142) of the inner member (20, 120) , and a stent carrying inner chamber (64, 164) disposed at the passageway (62, 162) of the distal section (52, 152) , the inner chamber (64, 164) being configured to releasably contain a stent.
摘要翻译：提供了用于可拆卸地接合内窥镜插入件的外部的至少一部分并用于输送支架的超范围的支架引入器（10,110）。实施例包括限定通道的内部构件（20,120）。内部构件包括设置在第一端部（22,122）处的外表面（36,136），内部内窥镜接合表面（34,134）和支架邻接约束件（38,138）。实施例还包括外部构件（50,150），其具有具有开口（58,158）的远端部分（52,152）和具有限定通道（62）的开口（60,160）的近端部分（54,154） 162），其尺寸设计成可滑动地容纳所述内部构件（20,120）的至少一部分（42,142），以及支架内部腔室（64,164），其设置在所述内部构件远端部分（52,152），所述内部腔室（64,164）构造成可释放地容纳支架。

3. 发明申请

WO2006033671A2 ENDOSCOPIC SURGICAL ACCESS DEVICES AND METHODS OF ARTICULATING AN EXTERNAL ACCESSORY CHANNEL 审中-公开
标题翻译：内窥镜手术访问装置及其外部附件通道的方法
公开(公告)号：WO2006033671A2
公开(公告)日：2006-03-30
申请号：PCT/US2005/012874
申请日：2005-04-15
申请人： WILSON-COOK MEDICAL INC. , DEVIERRE, Jacques , KENNEDY, Kenneth, C., II
发明人： DEVIERRE, Jacques , KENNEDY, Kenneth, C., II
IPC分类号： A61B1/018 , A61B1/00
CPC分类号： A61B1/0014 , A61B1/00087 , A61B1/00098 , A61B1/00101 , A61B1/00128 , A61B1/018
摘要： Devices and methods for detachably engaging an insertion section of an endoscope and selectively articulating an endoscopic surgical access channel are provided. A device (10, 70, 80) comprises an articulating main body (30) having a stationary first body (31, 71, 81), an articulatable second body (32, 72, 82, 92, 112) and coupler (19) having a mounting member (37, 43, 77, 84) and an articulation link member (36, 44, 76, 78, 85) configured to articulatively couple the second body to the first body. The stationary first body has a distal end (31'), a proximal end (31"), and a first longitudinal axis (39). The articulatable second body has a proximal opening (34, 74, 84) and a distal opening (35, 75, 85) defining an accessory channel member passageway (33, 73, 83), the distal opening having a second longitudinal axis (38, 89) oriented toward a space exterior to the first body distal end, wherein the second body longitudinal axis is capable of articulating relative to the first body longitudinal axis. The devices and methods, as taught herein, provide control over the position and/or orientation of a diagnostic, monitoring, scope, sewing device, cutting device, suturing device, forceps, grabbing device, instrument, or other tool within the visual field beyond the distal opening of the endoscope.
摘要翻译：提供了用于可拆卸地接合内窥镜的插入部分并且选择性地关联内窥镜手术进入通道的装置和方法。一种装置（10,70,80）包括具有固定的第一主体（31,71,81），可铰接的第二主体（32,72,82,92,112）和联接器（19）的铰接主体（30）具有安装构件（37,43,77,84）和铰接连接构件（36,44,76,78,85），其构造成将所述第二主体铰接地联接到所述第一主体。所述固定的第一主体具有远端（31'），近端（31“）和第一纵向轴线（39），所述可铰接的第二主体具有近端开口（34,74,84）和远端开口限定附件通道构件通道（33,73,83），所述远端开口具有朝向所述第一身体远端外部的空间定向的第二纵向轴线（38,89），其中所述第二身体纵向如本文教导的装置和方法提供对诊断，监测，范围，缝合装置，切割装置，缝合装置，镊子等的位置和/或取向的控制，所述装置和方法能够相对于第一身体纵向轴线铰接。抓取装置，仪器或视野内的其它工具超出内窥镜的远端开口。

4. 发明申请

WO2005011534A1 PROSTHETIC VALVE DEVICES AND METHODS OF MAKING SUCH DEVICES 审中-公开
标题翻译：前置阀装置和制造这种装置的方法
公开(公告)号：WO2005011534A1
公开(公告)日：2005-02-10
申请号：PCT/US2004/024730
申请日：2004-07-30
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A.
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2475 , A61F2220/0075
摘要： Prosthetic valve devices for implantation in body vessels, and methods of making same, are provided. The device has a main body (11) with first (12) and second (13) ends and defining a lumen (14), with the second end being inverted into the lumen. A valve is disposed at the second end (15). In multiple valve devices, valves are disposed at the first and second ends, and individually may be inverted into the lumen. The prosthetic valve devices may further include a support structure such as a stent (40). Methods of making a prosthetic valve device include providing a main body having first and second ends and defining a lumen, forming a valve at the second end, and inverting the second end into the lumen. Methods may further comprise forming multiple valves and may also include attaching a support structure.
摘要翻译：提供用于植入体内血管的假体瓣膜装置及其制造方法。该装置具有主体（11），其具有第一端（12）和第二端（13）端部并且限定内腔（14），其中第二端被倒置成内腔。阀设置在第二端（15）处。在多个阀装置中，阀设置在第一和第二端处，并且可以单独地倒置到内腔中。假体瓣膜装置还可以包括诸如支架（40）的支撑结构。制造假体瓣膜装置的方法包括提供具有第一端和第二端并限定内腔的主体，在第二端形成阀，并将第二端翻转成内腔。方法还可以包括形成多个阀并且还可以包括附接支撑结构。

5. 发明申请

WO2007078992A1 CATHETER CONNECTOR ASSEMBLIES AND METHODS FOR ATTACHING A CATHETER AND LUER ASSEMBLY 审中-公开
标题翻译：导管连接器总成及连接导管和导线组件的方法
公开(公告)号：WO2007078992A1
公开(公告)日：2007-07-12
申请号：PCT/US2006/048798
申请日：2006-12-22
申请人： WILSON-COOK MEDICAL INC. , WALLER, David, F. , THOMAS, Jeremy, Alexander
发明人： WALLER, David, F. , THOMAS, Jeremy, Alexander
IPC分类号： A61M25/00 , A61M39/12
CPC分类号： A61M25/0014 , A61M25/0026
摘要： Luer assemblies (10) are provided having first and second connectors (20, 40) operatively coupled and securing tails (72, 74) of a proximal end section (63) of a catheter (60) disposed therebetween. A method (200) for cutting a proximal end section (63) of a catheter (60) having distal and proximal ends (61, 63) is provided, a slit (70) in the proximal end section (63) exposing a catheter lumen (64, 65) and forming first and second tails (72, 74) having inner (78, 80, 84, 86), outer (82, 88), and peripheral (79, 81, 81', 85, 87, 87') engaging surfaces. Another method (100) secures catheter tails (72, 74) disposed between operatively coupled first and second connectors (20, 40), the first connector (20) having a distal insert (22) inserted into the exposed catheter lumen (64, 65) and a catheter engaging body (31) about which the catheter tails (72, 74) are disposed, and the second connector (20) having a catheter engaging body (53) disposed about the catheter tails (72, 74), wherein the connectors (20, 40) are configured (33, 52) to be operatively coupled to each other and to operatively couple the catheter tails (72, 74) disposed between the catheter engaging bodies (31, 53) of the first and second connectors (20, 40).
摘要翻译：鲁尔组件（10）设置有第一和第二连接器（20,40），其可操作地联接并固定设置在其间的导管（60）的近端部分（63）的尾部（72,74）。提供了一种用于切割具有远端和近端（61,63）的导管（60）的近端部分（63）的方法（200），所述近端部分（63）中的狭缝（70）暴露导管内腔（78），并且形成具有内部（78,80,84,86），外部（82,88）和周边（79,81,81'，85,87,87）的第一和第二尾部（72,74） '）接合表面。另一种方法（100）确保设置在可操作耦合的第一和第二连接器（20,40）之间的导管尾部（72,74），所述第一连接器（20）具有插入到暴露的导管内腔（64,65）中的远端插入件）和导管接合体（31），所述导管尾部（72,74）围绕所述导管接合体设置，并且所述第二连接器（20）具有围绕所述导管尾部（72,74）设置的导管接合体（53），其中，连接器（20,40）被构造为可操作地彼此耦合并且可操作地联接设置在第一和第二连接器（13,53）的导管接合体（31,53）之间的导管尾部（72,74） 20，40）。

6. 发明申请

WO2006101848A1 WIRE GUIDES HAVING NOVEL OUTER SURFACE AREAS AND RESERVOIRS FOR ENHANCING HYDROPHILIC PROPERTIES AND DELIVERING THERAPEUTIC AGENTS 审中-公开
标题翻译：具有新的外表面区域和用于增强水力特性和递送治疗剂的储存器的导线
公开(公告)号：WO2006101848A1
公开(公告)日：2006-09-28
申请号：PCT/US2006/009171
申请日：2006-03-15
申请人： WILSON-COOK MEDICAL, INC. , KENNEDY, Kenneth, II
发明人： KENNEDY, Kenneth, II
IPC分类号： A61M25/09 , A61M25/00
CPC分类号： A61M25/09 , A61M2025/0057 , A61M2025/091 , A61M2025/09133 , A61M2025/09175
摘要： Wire guide devices, and methods (300) of using same, having an elongate shaft (10, 110) with a first end portion (14, 114) and a flexible second end portion (16,116) having a non-coiled portion (24, 124) comprising a nominal outer circumference (22, 122) disposed about a longitudinal axis (18, 118) and having a first outer surface (12, 112) including the nominal outer circumference( 22, 122) and defining a first surface area (30, 130). Textures such as protuberances (26), indentations (28), peaks (160), and/or valleys (161) are disposed substantially circumferentially about the nominal outer circumference (22, 122) and defining an effective perimeter (21, 121) greater than the nominal outer circumference (22, 122) and having a second outer surface (20, 120) defining a second surface area (40, 140) greater than the first surface area (30, 130). Hydrophilic materials and therapeutic agents may be disposed partially on the second end portion (24, 124) and a coating (54, 74), and a membrane 84 may be disposed about non-coiled portion (24, 124) and coating (54, 74) to form reservoirs (73) or lumens (76) for delivering hydrophilic materials and delivering therapeutic agents.
摘要翻译：线引导装置和使用该导向装置的方法（300）具有带有第一端部（14,114）的细长轴（10,110）和具有非卷绕部分（24）的柔性第二端部（16,116） 124），包括围绕纵向轴线（18,118）设置的标称外圆周（22,122），并且具有包括标称外圆周（22,122）的第一外表面（12,112）并限定第一表面区域 30，130）。基本上围绕公称外圆周（22,122）周向地设置诸如突起（26），凹陷（28），峰（160）和/或谷（161）的纹理，并且限定更大的有效周长（21,121）（22,122），并且具有限定大于第一表面区域（30,130）的第二表面区域（40,140）的第二外表面（20,120）。亲水性材料和治疗剂可以部分地设置在第二端部（24,124）和涂层（54,74）上，并且膜84可以设置在非卷绕部分（24,124）周围， 74）以形成用于递送亲水材料并递送治疗剂的储存器（73）或腔（76）。

7. 发明申请

WO2006014383A1 STENT HAVING ARCUATE STRUTS 审中-公开
标题翻译：具有ARCUATE STRUTS的STENT
公开(公告)号：WO2006014383A1
公开(公告)日：2006-02-09
申请号：PCT/US2005/023625
申请日：2005-06-30
申请人： COOK INCORPORATED , AMARANT, Paul, D. , OSBORNE, Thomas, A.
发明人： AMARANT, Paul, D. , OSBORNE, Thomas, A.
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0037 , A61F2250/0039
摘要： Stents 10 are provided having a circumferential element 15 with first and second ends 11, 12, a longitudinal axis 14, and arcuate struts 20 disposed intermediate the ends. End portions 22, 23 of adjacent arcuate struts are joined by strut connections 30, 31, 31', 33, 35, 36, 38 formed at the first and second ends. The struts are spaced 60, 62, 64, 70, 72, 74 arcuately relative to a plane 14' that includes the longitudinal axis, such that they arc convexly 25 or concavely 24 relative to the plane. Another stent 110 has a tubular main body with a longitudinal axis 14, first and second ends 111, 112 defining a lumen 13 in communication with openings 17, 18 at the first and second ends, and circumferential elements 15 disposed along the tubular main body longitudinal axis, whereby one or more link members 16 join two or more of the circumferential elements. Methods 100 of using a stent having a circumferential element having arcuate struts connected by strut connections are also provided.
摘要翻译：提供具有圆周元件15的支架10，其具有第一和第二端部11,12，纵向轴线14和设置在端部中间的弓形支柱20。相邻弓形支柱的端部22,23通过形成在第一端和第二端的支柱连接件30,31,31'，33,35,36,38连接起来。支柱相对于包括纵向轴线的平面14'间隔开60,62,64,70,72,74，使得它们相对于该平面凸出25°或凹入24°。另一个支架110具有带纵向轴线14的管状主体，第一和第二端部111,112限定与第一和第二端部处的开口17,18相连通的管腔13，以及沿管状主体纵向由此一个或多个连杆构件16连接两个或更多个周向元件。还提供了使用具有通过支柱连接连接的具有弓形支柱的圆周元件的支架的方法100。

8. 发明申请

WO2005089846A1 MEDICAL DEVICES FOR SELECTIVELY AND ALTERNATELY ISOLATING BRONCHI OR LUNGS 审中-公开
标题翻译：用于选择性和全方位分离BRONCHI或LUNGS的医疗设备
公开(公告)号：WO2005089846A1
公开(公告)日：2005-09-29
申请号：PCT/US2005/007533
申请日：2005-03-08
申请人： COOK CRITICAL CARE INCORPORATED , KYLE, Garry, Wayne, Jr.
发明人： KYLE, Garry, Wayne, Jr.
IPC分类号： A61M16/04
CPC分类号： A61M16/04 , A61M16/0404 , A61M16/0427 , A61M16/0429 , A61M16/0434 , A61M16/0459 , A61M16/0475 , A61M16/0486
摘要： Devices and kits, for selectively and alternately isolating one of a pair of bronchi or lungs are provided. A main body (11) has proximal (12) and distal (13) ends defining a lumen (30), and a side port (22) and opening (15) formed near the distal end. An insert (40, 50) having first (41, 51) and second (42, 52) ends, and an aperture (45, 54) located at or near the second end, is configured to have the second end placed in the main body lumen. The insert aperture permits passageway to at least one of the main body side port or distal opening, while an exchangeable insert permits passageway to the other main body side port or opening, or optionally one insert may move between first and second positions to selectively and alternately permit passageway to the one or other main body side port or opening. Also provided are kits for selectively and alternately isolating one of a pair of bronchi or lungs.
摘要翻译：提供用于选择性地和交替地分离一对支气管或肺中的一个的装置和试剂盒。主体（11）具有限定内腔（30）的近端（12）和远端（13）端，以及在远端附近形成的侧端口（22）和开口（15）。具有第一（41,41）和第二（42,42）端部的插入件（40,50）和位于第二端处或附近的孔（45,54）构造成使第二端放置在主体体腔。插入孔允许通道进入主体侧端口或远端开口中的至少一个，而可更换的插入件允许通向另一个主体侧端口或开口的通道，或者可选地，一个插入件可以在第一和第二位置之间选择性地和交替地移动允许通道到一个或另一个主体侧端口或开口。还提供了用于选择性地和交替地分离一对支气管或肺中的一个的试剂盒。

9. 发明申请

WO2007053625A1 STEERABLE CATHETER DEVICES AND METHODS OF ARTICULATING CATHETER DEVICES 审中-公开
标题翻译：可变导管装置及其导管装置的方法
公开(公告)号：WO2007053625A1
公开(公告)日：2007-05-10
申请号：PCT/US2006/042490
申请日：2006-10-27
申请人： WILSON-COOK MEDICAL INC. , KENNEDY II, Kenneth, C.
发明人： KENNEDY II, Kenneth, C.
IPC分类号： A61M25/01
CPC分类号： A61M25/0155 , A61B1/0051 , A61B6/481 , A61B6/504 , A61B2017/003 , A61M25/0105 , A61M25/0136 , A61M25/0141
摘要： Steerable catheter devices (10) are provided having a proximal first end portion (14), an elongate intermediate portion (16), and a distal flexible second end portion (18) defining a longitudinal axis (11), and at least one channel (33, 37, 41, 45) having a proximal opening (31, 35, 39, 43) and terminating at an occluded distal end (32, 36, 40, 44) radially offset relative to the central longitudinal axis and positioned within the catheter flexible second end portion substantially straight in a relaxed position (70) and bent (80, 90) when the occluded distal end is under a change in internal fluid pressure. Optionally, the catheter further has a dye injection lumen (124) and a tool receiving passageway (24) extending from the first end portion to the second end portion. The occluded distal end is axially elastically distensible under an internal fluid pressure to deflect (thereby to steer) the catheter second end portion through the tortuous path of a vessel passageway when used percutaneously or working channel of an endoscope or endoscope accessory device.
摘要翻译：提供了可转向导管装置（10），其具有近端第一端部（14），细长中间部分（16）和限定纵向轴线（11）的远端柔性第二端部部分（18）和至少一个通道具有近侧开口（31,35,39,43）并终止于相对于中心纵向轴线径向偏移且位于导管内的封闭远端（32,36,40,44）柔性的第二端部在松弛位置（70）基本上是直的，并且当封闭的远端处于内部流体压力的变化时弯曲（80,90）。任选地，导管还具有从第一端部延伸到第二端部的染料注入腔（124）和工具接收通道（24）。当内窥镜或内窥镜附件装置经皮或工作通道使用时，封闭的远端在内部流体压力下轴向弹性扩张，以使导管第二端部穿过血管通道的曲折路径偏转（从而引导）。

10. 发明申请

WO2006065913A1 FLEXIBLE SURGICAL NEEDLE DEVICE 审中-公开
标题翻译：柔性手术针装置
公开(公告)号：WO2006065913A1
公开(公告)日：2006-06-22
申请号：PCT/US2005/045264
申请日：2005-12-14
申请人： WILSON-COOK MEDICAL INC. , WAXMAN, Irving , WALLER, David, F.
发明人： WAXMAN, Irving , WALLER, David, F.
IPC分类号： A61B10/00
CPC分类号： A61B10/0233 , A61B10/0283 , A61B10/04 , A61B2010/045 , A61B2017/00867
摘要： Medical devices (11, 51), surgical needle device systems (10), and methods (100) for utilizing an elongate surgical needle (54) that may be used through an endoscope working channel or through an external accessory channel device used with an endoscope are provided. The needle (54) has a proximal end (90) and a flexible distal end (91), an opening (92) at or near the proximal end (90) and an opening (93) at or near the distal end (91), the openings (92, 93) defining a channel (83). The surgical needle distal end (91) comprises a tissue engaging section (94) and an intermediate section (95) being operatively coupled in an axial direction. The tissue engaging section (94) and intermediate section (95) have different flexibility such that the tissue engaging section has greater flexibility than the intermediate section. Optionally, the needle distal end (91) has a preformed bend (97) at or near the tissue engaging section (94), the preformed bend (97) capable of being constrained to a substantially linear configuration and capable of returning to the preformed configuration when unconstrained.
摘要翻译：医疗装置（11,51），外科用针装置系统（10）以及用于利用可以通过内窥镜工作通道使用的细长的外科用针（54）或通过与内窥镜一起使用的外部附件通道装置被提供。针（54）具有近端（90）和柔性远端（91），在近端（90）处或附近的开口（92）和在远端（91）处或附近的开口（93），所述开口（92,93）限定通道（83）。外科针头远端（91）包括组织接合部分（94）和在轴向上可操作地联接的中间部分（95）。组织接合部分（94）和中间部分（95）具有不同的柔性，使得组织接合部分具有比中间部分更大的灵活性。可选地，针远端（91）在组织接合部分（94）处或附近具有预成型的弯曲部（97），预成型的弯曲部（97）能够被约束为基本线性的构造并且能够返回到预成形构造当不受约束

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