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1. 发明申请

WO2008013777A2 MEDICAL DEVICE INTRODUCER WITH DOCKING ARRANGEMENT 审中-公开
标题翻译：医疗设备引言与锁定安排
公开(公告)号：WO2008013777A2
公开(公告)日：2008-01-31
申请号：PCT/US2007/016574
申请日：2007-07-24
申请人： WILLIAM A. COOK AUSTRALIA PTY. LTD. , COOK INCORPORATED , WILLIAM COOK EUROPE APS , HARTLEY, David, Ernest , IVANCEV, Krasnodar , LAWRENCE-BROWN, Michael
发明人： HARTLEY, David, Ernest , IVANCEV, Krasnodar , LAWRENCE-BROWN, Michael
CPC分类号： A61F2/95 , A61F2/0095 , A61F2002/9517
摘要： A stent graft introducer has a nose cone dilator (8) and a distally opening capsule ( 18) on the nose cone dilator, a balloon guide (2, 30) extending into the capsule and affixed therein. Upon completion of deployment of a stent graft, a balloon catheter (96) including an inflatable balloon (98) thereon can be advanced over the balloon guide at least partially into the nose cone whereby the balloon can be inflated therein to provide a smooth transition from the nose cone to a delivery sheath ( 10) for retraction of the nose cone dilator through the deployed stent graft. The balloon guide can be a guide wire catheter (2) or a separate wire (30).
摘要翻译：支架移植物导引器具有鼻锥扩张器（8）和鼻锥体扩张器上的远端开口囊（18），气囊引导件（2,30）延伸到胶囊中并固定在其中。在完成展开支架移植物后，包括其上的可膨胀气囊（98）的球囊导管（96）能够至少部分地进入到鼻锥体中，从而球囊可在其中膨胀以提供平滑过渡鼻锥体到达递送护套（10），用于通过展开的支架移植物缩回鼻锥扩张器。气球引导件可以是导丝导管（2）或单独的导线（30）。

2. 发明申请

WO2012071095A1 SCORING BALLOON AND METHOD OF MAKING SAME 审中-公开
标题翻译：分选气球及其制作方法
公开(公告)号：WO2012071095A1
公开(公告)日：2012-05-31
申请号：PCT/US2011/049968
申请日：2011-08-31
申请人： COOK MEDICAL TECHNOLOGIES LLC , AGGERHOLM, Steen , ELGAARD, Per , HJORT, Kjeld , LYSGAARD, Thomas
发明人： AGGERHOLM, Steen , ELGAARD, Per , HJORT, Kjeld , LYSGAARD, Thomas
IPC分类号： A61B17/32 , A61B17/3207 , A61M25/10 , A61B17/22
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/1029 , A61M2025/1086 , Y10T29/49826
摘要： A scoring balloon (10) includes a generally cylindrical and straight body portion (12) and both ends of the body portion (12) end cone portions (14, 16). At both extremities of the end cone portions (14, 16) there are neck portions (18,20) which are fixed to a catheter or carrier element (22). A plurality of scoring elements (24) extend from one end of the balloon (10) to the other. Each scoring element (24) has a central uniform section (26) which extends along the body portion (12) of the balloon and tapering sections (28,30) which extend from the central section (26) and along the balloon end cones (14, 16). The tapering sections (28,30) taper from a height generally consistent with the central section (26) to a lower height along the direction of taper of the balloon end cones (18,20). This reduction in height of the scoring elements (24) as the balloon narrows enhances the flexibility of the balloon at the cone portions (18,20) and also ensures that there is no abrupt change in the height of the scoring elements (24) which could present a shoulder or other edge able to snag on a vessel wall or medical device located in a patient's lumen.
摘要翻译：刻痕球（10）包括大致圆柱形且直的主体部分（12），并且主体部分（12）的两端端部锥形部分（14,16）。在端锥部分（14,16）的两端，存在固定到导管或载体元件（22）的颈部（18,20）。多个刻痕元件（24）从球囊（10）的一端延伸到另一个。每个刻痕元件（24）具有中心均匀部分（26），该中心均匀部分沿着球囊的主体部分（12）延伸，并且从中心部分（26）延伸并且沿球囊端锥体 14，16）。锥形部分（28,30）从大致与中心部分（26）一致的高度沿球囊端锥体（18,20）的锥度方向逐渐变小。随着球囊狭窄，刻痕元件（24）的高度的这种降低增强了球囊在锥形部分（18,20）处的柔性，并且还确保了刻痕元件（24）的高度不会突然改变，可以呈现能够阻塞在位于患者管腔中的血管壁或医疗装置上的肩部或其他边缘。

3. 发明申请

WO2010044874A1 SYSTEM AND METHOD FOR DEPLOYING AND POSITIONING AN ENDOVASCULAR DEVICE 审中-公开
标题翻译：用于分配和定位内部血管装置的系统和方法
公开(公告)号：WO2010044874A1
公开(公告)日：2010-04-22
申请号：PCT/US2009/005642
申请日：2009-10-16
申请人： MED INSTITUTE, INC. , WILLIAM COOK EUROPE APS , DIERKING, William, Kurt , ORR, David, E. , PETERSEN, Jesper, S.
发明人： DIERKING, William, Kurt , ORR, David, E. , PETERSEN, Jesper, S.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9511 , A61F2002/9665
摘要： A dilator tip (100) for deploying and positioning an endovascular device (570) at a treatment site includes an elongate body (105) having at least two substantially longitudinal channels (110) in an outer surface (105s) of the body and at least two deployment struts (115). Each deployment strut (115) has a free end (120) releasably attached to a proximal edge (575) of an endovascular device (570) to be deployed, a constrained end (125) restrained within one of the longitudinal channels (110), and a pivot portion (130) between the free end (120) and the constrained end (125). In an undeployed configuration of the dilator tip (100), the free ends (120) reside within the longitudinal channels (110), and in a deployed configuration of the dilator tip (100), the free ends (120) are pivotally extended away from the longitudinal channels (110) by way of the pivot portions (130).
摘要翻译：用于在处理部位展开和定位血管内装置（570）的扩张器尖端（100）包括细长主体（105），其在主体的外表面（105s）中具有至少两个基本上纵向的通道（110），并且至少两个部署支柱（115）。每个部署支柱（115）具有可释放地附接到待部署的血管内装置（570）的近侧边缘（575）的自由端（120），限制在所述纵向通道（110）之一内的约束端（125）以及在自由端（120）和约束端（125）之间的枢轴部分（130）。在扩张器尖端（100）的未部署构造中，自由端（120）位于纵向通道（110）内，并且在扩张器尖端（100）的展开构造中，自由端（120）被枢转地延伸远离从所述纵向通道（110）通过所述枢转部分（130）。

4. 发明申请

WO2010024882A1 COATED STENT 审中-公开
标题翻译：涂层
公开(公告)号：WO2010024882A1
公开(公告)日：2010-03-04
申请号：PCT/US2009/004832
申请日：2009-08-25
申请人： COOK INCORPORATED , PARKER, Fred, T.
发明人： PARKER, Fred, T.
IPC分类号： A61F2/82 , B05D1/00
CPC分类号： A61F2/07 , A61F2/915 , A61F2002/072 , A61F2240/001
摘要： A coated stent (20) for use in a medical procedure and methods of manufacturing the coated stent (20) are described. A stent component (30) has an expanded state in which an inner diameter (d s ) of the stent (30) is less than or equal to an outer diameter (d c2 ) of a coating (40), thereby causing an inner surface (35) of the stent (30) to engage the outer surface (42) of the coating (40). In one exemplary method of manufacture, the stent (30) is disposed over the coating (40) when the coating (40) is provided with a first, smaller outer diameter (d c1 ). The coating (40) then is radially expanded to a second, larger outer diameter (d C2 ), which is greater than or equal to the inner diameter (d s ) of the stent (30), to cause the outer surface (42) of the coating (40) to engage the inner surface (35) of the stent (30).
摘要翻译：描述了用于医疗过程的涂覆支架（20）和制造涂层支架（20）的方法。支架构件（30）具有膨胀状态，其中支架（30）的内径（ds）小于或等于涂层（40）的外径（dc2），从而使内表面（35））以接合涂层（40）的外表面（42）。在一种示例性制造方法中，当涂层（40）设置有第一较小外径（dc1）时，支架（30）设置在涂层（40）上方。然后将涂层（40）径向扩张到大于或等于支架（30）的内径（ds）的第二较大外径（dC2），以使得外护罩（40）的外表面（42）涂层（40）以与支架（30）的内表面（35）接合。

5. 发明申请

WO2010024871A1 BALLOON CATHETERS HAVING A PLURALITY OF NEEDLES FOR THE INJECTION OF ONE OR MORE THERAPEUTIC AGENTS 审中-公开
标题翻译：有一个或多个治疗药物注射多余针头的气球导管
公开(公告)号：WO2010024871A1
公开(公告)日：2010-03-04
申请号：PCT/US2009/004811
申请日：2009-08-24
申请人： MED INSTITUTE, INC. , ORR, David, E.
发明人： ORR, David, E.
IPC分类号： A61M25/10 , A61M29/02 , A61M37/00
CPC分类号： A61M25/1002 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M25/104 , A61M2025/0004 , A61M2025/0093 , A61M2025/1013 , A61M2025/105 , A61M2025/1072 , A61M2025/1086 , A61M2037/003
摘要： There are disclosed apparatus and methods for treating tissue by delivering at least one therapeutic agent into the tissue. In one embodiment, the apparatus comprises a catheter (30, 40) and a balloon member (150) disposed on a distal region of the catheter. A plurality of pockets (164) are disposed on the balloon member (150), and a plurality of needles (180) are associated with each of the plurality of pockets. The plurality of needles (180) are configured to engage tissue when the balloon (150) is in the inflated state, and further are configured to disperse a therapeutic agent from an associated pocket (164) into the tissue when the balloon (150) is in the inflated state. A first needle (180a) of the plurality of needles may comprise a length that is different than a second needle (180b), permitting the delivery of first and second therapeutic agents to different depths within the tissue.
摘要翻译：公开了通过将至少一种治疗剂递送到组织中来治疗组织的装置和方法。在一个实施例中，该装置包括设置在导管的远侧区域上的导管（30,40）和球囊构件（150）。多个袋（164）设置在球囊构件（150）上，并且多个针（180）与多个凹穴中的每一个相关联。多个针（180）构造成当球囊（150）处于充气状态时接合组织，并且还被配置成当球囊（150）为（或）球囊）时将治疗剂从相关联的口袋（164）分散到组织中处于膨胀状态。多个针的第一针（180a）可以包括与第二针（180b）不同的长度，允许第一和第二治疗剂递送到组织内的不同深度。

6. 发明申请

WO2005112821A3 ENHANCED BIOLOGICAL FIXATION OF GRAFTS 审中-公开
公开(公告)号：WO2005112821A3
公开(公告)日：2005-12-01
申请号：PCT/US2005/017878
申请日：2005-05-20
申请人： MED INSTITUTE, INC. , LEEWOOD, Alan, R. , BAHLER, Clinton, D. , SUN, Jichao , FEARNOT, Neal, E.
发明人： LEEWOOD, Alan, R. , BAHLER, Clinton, D. , SUN, Jichao , FEARNOT, Neal, E.
IPC分类号： A61F2/06 , A61F2/00
摘要： A stent graft (1) has a substantially tubular body having a proximal and a distal end, at least the proximal end (5) comprising a region intended in use to engage a landing zone in a vessel in the body in use, the region comprising a mechanical treatment to enhance biological fixation to the landing zone. The mechanical treatment can be provision of apertures (92), provision of relatively rigid engagement portions (17), impregnation with a SIS gel or digest (72) and mounting of a cuff or collar of SIS (60) or some other biocompatible material.

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