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1. 发明申请

WO2005016962A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES 审中-公开
标题翻译：用于治疗免疫相关疾病的组合物和方法
公开(公告)号：WO2005016962A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/026249
申请日：2004-08-11
申请人： GENENTECH, INC. , ABBAS, Alexander , CLARK, Hilary , OUYANG, Wenjun , WILLIAMS, Mickey, P. , WOOD, William, I. , WU, Thomas, D.
发明人： ABBAS, Alexander , CLARK, Hilary , OUYANG, Wenjun , WILLIAMS, Mickey, P. , WOOD, William, I. , WU, Thomas, D.
IPC分类号： C07K14/47
CPC分类号： C12Q1/6837 , C07K14/47 , C12N9/2417 , C12Y302/01001 , G01N33/53 , G01N33/564 , G01N33/6893 , G01N2800/24
摘要： The present invention relates to composition containing novel proteins and method of using those compositions for the dignosis and treatment of immune related diseases.
摘要翻译：本发明涉及含有新蛋白质的组合物和使用这些组合物进行免疫相关疾病的治疗和治疗的方法。

2. 发明申请

WO2004081199A2 NOVEL COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASE 审中-公开
标题翻译：新型组合物和治疗免疫相关疾病的方法
公开(公告)号：WO2004081199A2
公开(公告)日：2004-09-23
申请号：PCT/US2004/007862
申请日：2004-03-10
申请人： GENENTECH, INC. , BALDWIN, Daryl , BODARY, Sarah , CLARK, Hilary , FONG, Sherman , GURNEY, Austin, L. , WILLIAMS, P., Mickey
发明人： BALDWIN, Daryl , BODARY, Sarah , CLARK, Hilary , FONG, Sherman , GURNEY, Austin, L. , WILLIAMS, P., Mickey
IPC分类号： C12N
CPC分类号： C07K14/4713 , A61K38/00 , C07K14/47
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related disease.
摘要翻译：本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。

4. 发明申请

WO2004028447A2 NOVEL COMPOSITIONS AND METHODS FOR THE TREATMENT OF PSORIASIS 审中-公开
标题翻译：新型组合物和治疗PSORIASIS的方法
公开(公告)号：WO2004028447A2
公开(公告)日：2004-04-08
申请号：PCT/US2003/027382
申请日：2003-08-28
申请人： GENENTECH, INC. , BODARY, Sarah , CLARK, Hilary , JACKMAN, Janet , SCHOENFELD, Jill , WILLIAMS, P. Mickey , WOOD, William I. , WU, Thomas D.
发明人： BODARY, Sarah , CLARK, Hilary , JACKMAN, Janet , SCHOENFELD, Jill , WILLIAMS, P. Mickey , WOOD, William I. , WU, Thomas D.
IPC分类号： A61K
CPC分类号： C07K14/705 , A61K38/00 , C07K14/47
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of psoriasis.
摘要翻译：本发明涉及含有新蛋白质的组合物和使用这些组合物用于诊断和治疗牛皮癣的方法。

5. 发明申请

WO2004024068A3 NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES 审中-公开
公开(公告)号：WO2004024068A3
公开(公告)日：2004-03-25
申请号：PCT/US2003/028202
申请日：2003-09-09
申请人： GENENTECH, INC.
发明人： BALDWIN, Daryl, T. , BODARY, Sarah, C. , CHAN, Andrew, C. , CLARK, Hilary , JACKMAN, Janet, K. , WOOD, William, I.
IPC分类号： A61K39/00
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases.

6. 发明申请

WO2004004649A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES 审中-公开
标题翻译：用于治疗免疫相关疾病的组合物和方法
公开(公告)号：WO2004004649A2
公开(公告)日：2004-01-15
申请号：PCT/US2003/021083
申请日：2003-07-08
申请人： GENENTECH, INC.
发明人： CHIU, Henry , CLARK, Hilary , DENNIS, Kathryn , FONG, Sherman , SCHOENFELD, Jill , WOOD, William , WU, Thomas
IPC分类号： A61K
CPC分类号： C07K14/47 , A61K38/00 , C07K14/4713 , G01N33/564
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译：本发明涉及含有新蛋白质的组合物和使用这些组合物诊断和治疗免疫相关疾病的方法。

7. 发明申请

WO2012120428A1 NOVEL KINASE INHIBITORS 审中-公开
标题翻译：新鲜激素抑制剂
公开(公告)号：WO2012120428A1
公开(公告)日：2012-09-13
申请号：PCT/IB2012/051005
申请日：2012-03-02
申请人： NOVARTIS AG , BURGER, Matthew , NISHIGUCHI, Gisele , MACHAJEWSKI, Timothy, D. , RICO, Alice , SIMMONS, Robert, Lowell , SMITH, Aaron, R. , TAMEZ, Victoriano, Jr. , TANNER, Huw , WAN, Lifeng
发明人： BURGER, Matthew , NISHIGUCHI, Gisele , MACHAJEWSKI, Timothy, D. , RICO, Alice , SIMMONS, Robert, Lowell , SMITH, Aaron, R. , TAMEZ, Victoriano, Jr. , TANNER, Huw , WAN, Lifeng
IPC分类号： C07D213/75 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , A61K31/444 , A61P35/00 , A61P37/00
CPC分类号： C07D213/75 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention provides compounds of Formula I: (I) and related compounds as further described herein, and pharmaceutical compositions comprising these compounds. The invention further provides methods to use these compounds and compositions for treating disorders associated with undesired levels of Pirn kinase activity, including cancers and autoimmune disorders.
摘要翻译：本发明提供式I化合物：（I）和本文进一步描述的相关化合物，以及包含这些化合物的药物组合物。本发明进一步提供了使用这些化合物和组合物治疗与不想要的皮激素活性水平相关的疾病（包括癌症和自身免疫性疾病）的方法。

8. 发明申请

WO2006068822A1 NOTCH RECEPTOR AGONISTS AND USES 审中-公开
标题翻译： NOTCH受体激动剂和用途
公开(公告)号：WO2006068822A1
公开(公告)日：2006-06-29
申请号：PCT/US2005/044123
申请日：2005-12-07
申请人： GENENTECH, INC. , DE SAUVAGE, Frederic, J. , GAO, Wei-Qiang , LEOW, Ching Ching , WANG, Xi-de , ZHA, Jiping
发明人： DE SAUVAGE, Frederic, J. , GAO, Wei-Qiang , LEOW, Ching Ching , WANG, Xi-de , ZHA, Jiping
IPC分类号： A61K38/17 , A61K39/395 , A61P13/08 , C12Q1/68 , G01N33/574
CPC分类号： C07K16/28 , A61K38/1703 , C07K2319/30 , C12Q1/6886 , C12Q2600/136 , G01N33/5008 , G01N33/5011 , G01N33/5044 , G01N33/57434 , G01N33/68 , G01N2500/00
摘要： The present invention is directed to methods of alleviating prostate disorders by activation of the Notch 1 receptor. Also provided herein are methods for detecting and diagnosing prostate disorders, wherein the specific disorder is prostate cancer.
摘要翻译：本发明涉及通过Notch1受体活化来减轻前列腺障碍的方法。本文还提供了用于检测和诊断前列腺疾病的方法，其中特异性病症是前列腺癌。

9. 发明申请

WO2005061889A1 PUMPS 审中-公开
标题翻译：水泵
公开(公告)号：WO2005061889A1
公开(公告)日：2005-07-07
申请号：PCT/GB2004/005219
申请日：2004-12-14
申请人： ITW LIMITED , SMITH, Alan
发明人： SMITH, Alan
IPC分类号： F04B17/03
CPC分类号： F04B9/042 , F04B17/03 , F04B2201/0201 , Y10T74/2101 , Y10T74/2107
摘要： A pump primarily for liquid paint comprising first and second pistons (19, 21) reciprocable rectilinearly in respective first and second cylinders (17, 18), said first and second pistons being moved relative to their respective pistons by operation of an A. C. electric motor (13) the rotary output shaft of which is coupled to said first and second pistons by means including a constant velocity cam (31) and cam follower (32, 33) mechanism converting rotary motion of the output shaft into reciprocatory motion of said first and second pistons 180° out of phase with one another.
摘要翻译：一种主要用于液体涂料的泵，包括在相应的第一和第二气缸（17,18）中直线地往复运动的第一和第二活塞（19,21），所述第一和第二活塞通过AC电动机的操作相对于它们各自的活塞移动 13），其旋转输出轴通过包括恒速凸轮（31）和凸轮从动件（32,33）的机构联接到所述第一和第二活塞，机构将输出轴的旋转运动转换成所述第一和第二活塞的往复运动活塞彼此相位相差180°。

10. 发明申请

WO2005049853A2 COMPOSITIONS AND METHODS FOR SCREENING PRO-APOPTOTIC COMPOUNDS 审中-公开
标题翻译：筛选PRO-APOPTOTIC化合物的组合物和方法
公开(公告)号：WO2005049853A2
公开(公告)日：2005-06-02
申请号：PCT/US2004/038631
申请日：2004-11-08
申请人： GENENTECH, INC. , BURNHAM INSTITUTE , FAIRBROTHER, Wayne J. , FRANKLIN, Matthew C. , ACKERLY WALLWEBER, Heidi Jenii , KADKHODAYAN, Saloumeh , SALVESEN, Guy , VUCIC, Domagoj
发明人： FAIRBROTHER, Wayne J. , FRANKLIN, Matthew C. , ACKERLY WALLWEBER, Heidi Jenii , KADKHODAYAN, Saloumeh , SALVESEN, Guy , VUCIC, Domagoj
IPC分类号： C12Q
CPC分类号： C07K14/4747 , C07H21/04 , C07K2319/00 , C12Q1/37 , G01N2333/96466 , G01N2510/00
摘要： The present invention is directed to compositions of matter useful for the enhancement of apoptosis in mammals and to methods of using those compositions of matter for the same
摘要翻译：本发明涉及用于增强哺乳动物细胞凋亡的物质组合物和使用这些组合物的物质组合物。

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