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1. 发明申请

WO2017099801A1 COMPOSITIONS, KITS, AND METHODS TO DETECT HIV VIRUS 审中-公开
标题翻译：检测HIV病毒的组合物，试剂盒和方法
公开(公告)号：WO2017099801A1
公开(公告)日：2017-06-15
申请号：PCT/US2015/065312
申请日：2015-12-11
申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人： LIU, Changchun , SHERRIL-MIX, Scott , BAU, Haim, H. , BUSHMAN, Frederic, D. , OCWIEJA, Karen, E.
IPC分类号： C12Q1/16 , C12Q1/68 , C12Q1/70
CPC分类号： C12Q1/703 , C12Q1/68 , C12Q2600/158 , G01N33/56988
摘要： Provided herein include compositions comprising a primer having the nucleic acid sequence of ACeIN-F3_c, a primer having the nucleic acid sequence of ACeIN-B3_a, a primer having the nucleic acid sequence of ACeIN-B3_b, a primer having the nucleic acid sequence of ACelN-FIP e, a primer having the nucleic acid sequence of ACelN-FIP f, a primer having the nucleic acid sequence of ACelN-BIP (or ACelN-BIP-song), a primer having the nucleic acid sequence of ACelN-LF; and a primer having the nucleic acid sequence of ACelN-LB. Also provided are methods of detecting human immunodeficiency virus (HIV) nucleic acids in a sample comprising performing reverse transcription-based loop mediated isothermal amplification (RT-LAMP) on a sample using the previously disclosed compositions.
摘要翻译：本文提供的组合物包括：包含具有ACeIN-F3_c的核酸序列的引物，具有ACeIN-B3_a的核酸序列的引物，具有ACeIN-B3_b的核酸序列的引物，具有ACelN-FIP e的核酸序列的引物，具有ACelN-FIP女，具有ACelN-BIP（或ACelN-BIP-曲），具有核酸的引物的核酸序列的引物的核酸序列的引物 ACelN-LF的酸序列; 和具有ACelN-LB的核酸序列的引物。还提供了检测样品中的人类免疫缺陷病毒（HIV）核酸的方法，包括使用先前公开的组合物对样品进行基于逆转录的环介导的等温扩增（RT-LAMP）。

2. 发明申请

WO2015148367A1 CHEMICALLY SWITCHABLE ULTRAVIOLET PHOTOLUMINESCENCE 审中-公开
标题翻译：化学开关超紫外光致发光
公开(公告)号：WO2015148367A1
公开(公告)日：2015-10-01
申请号：PCT/US2015/021983
申请日：2015-03-23
申请人： DREXEL UNIVERSITY , THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人： SPANIER, Jonathan, E. , GU, Zongquan , ISLAM, Mohammad, A. , SALDANA-GRECO, Diomedes , RAPPE, Andrew, Marshall
IPC分类号： G01N21/00
CPC分类号： G01N21/75 , G01N21/6489 , G01N2021/7786
摘要： The present disclosure pertains to the use of intense, narrow-linewidth surface, chemically-switchable ultraviolet photoluminescence from radiative recombination of the two-dimensional electron liquid with photo-excited holes in complex oxide heterostructures, such as LaAlO 3 /SrTiO 3 (LAO/STO). Such photoluminescence from the interface between the upper and lower layers can be suppressed and restored reversibly under oxidizing and reducing conditions, respectively, as induced by chemisorption and reversal of chemisorption on the exposed surface of the heterostructure's upper member. Making use of this chemically-switchable ultraviolet photoluminescence, the present disclosure provides, inter alia , systems for detection of a chemical species, methods for determining the absence or presence of a chemical species in a sample, optoelectronic devices, and methods for producing optoelectronic devices.
摘要翻译：本公开涉及使用强的窄线宽表面，来自二维电子液体的辐射复合的化学可切换的紫外光致发光与复合氧化物异质结构（如LaAlO 3 / SrTiO 3（LAO / STO））中的光激发空穴的使用，。在氧化和还原条件下，分别在上，下层之间界面处的这种光致发光可以被抑制和可逆地恢复，这是由化学吸附引起的，并且异质结构的上部成员的暴露表面上的化学吸附反转。利用该化学可切换的紫外光致发光，本公开尤其提供了用于检测化学物质的系统，用于确定样品中化学物质的存在或不存在的方法，光电子器件以及用于制造光电器件的方法。

3. 发明申请

WO2015105607A1 NON-THERMAL PLASMA CLEANING OF DIRTY SYNTHESIS GAS 审中-公开
标题翻译：非热合成气体的非热等离子体清洁
公开(公告)号：WO2015105607A1
公开(公告)日：2015-07-16
申请号：PCT/US2014/069212
申请日：2014-12-09
申请人： DREXEL UNIVERSITY
发明人： FRIDMAN, Alexander , NIRENBERG, Gary , RABINOVICH, Alexander , CHERNETS, Ivan
IPC分类号： B01J19/08
CPC分类号： C01B3/342 , B01J7/00 , B01J19/088 , B01J2219/0809 , B01J2219/0815 , B01J2219/0828 , B01J2219/083 , B01J2219/0832 , B01J2219/0869 , B01J2219/0871 , B01J2219/0875 , B01J2219/0883 , B01J2219/0884 , B01J2219/0894 , C01B3/50 , C01B2203/048 , C01B2203/062 , C01B2203/066 , C01B2203/0861 , C01B2203/84 , H05H1/48 , H05H2001/4695
摘要： The inventions described herein are directed to technologies for reforming high temperature feedstreams into clean synthesis gas, more particularly, reactor configurations and methods for reforming pyrogas using non-thermal plasmas. One embodiment provides a plasma reactor comprising: (a) a substantially cylindrical reactor wall having a first closed proximal end and a second open distal end, wherein at least a portion of said wall is configured to comprise a first electrode; and (b) a second elongated electrode electrically separated from the first electrode by an electrical insulator, said electric insulator forming either part or all of the first closed end of the reactor or positioned proximate thereto; and configured to be capable of generating and maintaining a gliding arc plasma discharge within a zone in said reactor.
摘要翻译：本文所述的发明涉及将高温进料流重整成清洁合成气的技术，更具体地，涉及使用非热等离子体重整焦糖的反应器构型和方法。一个实施例提供了一种等离子体反应器，包括：（a）具有第一封闭近端和第二开放远端的基本上圆柱形的反应器壁，其中所述壁的至少一部分构造成包括第一电极; 和（b）通过电绝缘体与第一电极电分离的第二细长电极，所述电绝缘体形成反应器的第一封闭端的一部分或全部或者位于其附近; 并且被配置为能够在所述反应器的区域内产生并保持滑动电弧等离子体放电。

4. 发明申请

WO2015095491A1 PLASMA SEPARATOR APPARATUS AND ASSOCIATED METHODS 审中-公开
标题翻译：等离子体分离器装置及相关方法
公开(公告)号：WO2015095491A1
公开(公告)日：2015-06-25
申请号：PCT/US2014/071099
申请日：2014-12-18
申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人： LIU, Changchun , BAU, Haim, H. , MAUK, Michael, G.
IPC分类号： A61M1/34 , B01D61/18 , B01D21/24
CPC分类号： B01D63/087 , A61M1/3496 , A61M2202/0415 , A61M2205/70 , B01D61/147 , B01D63/08 , B01D69/06 , B01D2313/58 , G01N33/491
摘要： A plasma separator includes a vertical chamber with a membrane or membranes partially or fully covering the internal chamber walls and forming an inner cavity to accommodate whole blood. The plasma separator further includes a plasma collection space separated from the inner cavity with one or more membranes and a plasma removal port.
摘要翻译：等离子体分离器包括具有膜的垂直室或部分或完全覆盖内室壁的膜，并形成内腔以容纳全血。等离子体分离器还包括从内腔与一个或多个膜和等离子体去除端口分离的等离子体收集空间。

5. 发明申请

WO2014197460A1 METHODS FOR DIAGNOSING AND TREATING BICUSPID AORTIC VALVE AND/OR AORTOPATHIES 审中-公开
标题翻译：用于诊断和治疗BICUSPID动脉瓣和/或AORTOPATHIES的方法
公开(公告)号：WO2014197460A1
公开(公告)日：2014-12-11
申请号：PCT/US2014/040662
申请日：2014-06-03
申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人： FERRARI, Giovanni , BRANCHETTI, Emanuela
IPC分类号： C12Q1/25 , G01N33/50 , G01N33/48
CPC分类号： G01N33/6854 , A61B6/03 , A61B8/0883 , A61B8/12 , G01N33/6893 , G01N2333/70503 , G01N2800/324 , G01N2800/329 , G01N2800/52
摘要： Provided herein are methods for identifying and treating BAV disease and/or aortopathy in a subject, and methods of improving outcome in a subject. The subject may be asymptomatic of BAV disease and/or aortopathy, experiencing symptoms of BAV disease and/or aortopathy, have BAV disease and/or aortopathy, or be a blood relative of an individual having BAV disease and/or aortopathy. Levels of sRAGE in the subject's biological sample are determined, compared to a control biological sample, and used as an indicator for the presence and severity of BAV disease and/or aortopathies, a tool to screen family members, and an indicator of the proper surgical or treatment regimens.
摘要翻译：本文提供了用于鉴定和治疗受试者的BAV疾病和/或病变的方法以及改善受试者的结果的方法。受试者可能无症状的BAV疾病和/或病变，经历BAV疾病和/或病变的症状，具有BAV疾病和/或病变，或者是具有BAV疾病和/或病变的个体的血液相对。确定受试者生物样品中sRAGE的水平，与对照生物样品相比较，并用作BAV疾病和/或感染病史的存在和严重程度的指标，筛选家庭成员的工具，以及适当手术的指标或治疗方案。

6. 发明申请

WO2014186447A1 RFID PLAQUE BOX 审中-公开
公开(公告)号：WO2014186447A1
公开(公告)日：2014-11-20
申请号：PCT/US2014/037976
申请日：2014-05-14
申请人： GAMING PARTNERS INTERNATIONAL CORPORATION
发明人： GELINOTTE, Emmanuel , MOLINA, Bernard , CHOI, Miguel , MCCARTHY, Scott , RAZ, Benjamin , CLARK, Kirsten , GRONAU, Gregory, Scott , VICAIRE, Regis Marcel, Roger
IPC分类号： B65D85/00 , H04Q5/22 , A47B88/00
CPC分类号： G06K7/10336 , G06K7/10425 , G06Q20/352 , G07F7/0893 , G07G1/00
摘要： An RFID plaque box provides secure storage and protection of value tokens (e.g., gaming plaques and jetons) of all sizes and shapes (e.g., rectangular, square, oval or round) and delivers real-time counting and movement details in both high and low frequency RF environments. The RFID plaque box allows plaques or jetons to be accounted for as part of the table's inventory along with the RFID chip tray's inventory (when installed). The RFID plaque box is provided as a fixed storage area that is situated below the plan of the gaming table alongside the RFID chip tray (when provided) with a lid very similar to that of the RFID chip tray or provided in a pop-up mechanism whereby the RFID plaque box is integrated into a gaming table such that when the top surface of the RFID plaque box is pushed, the RFID plaque box will pop-up to lift the stacks of plaques or jetons for access.
摘要翻译： RFID标签盒提供安全的存储和保护所有尺寸和形状（例如，矩形，正方形，椭圆形或圆形）的价值标记（例如，游戏板和布龙），并提供高低的实时计数和移动细节频率RF环境。 RFID标签盒允许将斑块或布隆顿作为桌子库存的一部分以及RFID芯片托盘的库存（安装时）。 RFID标签盒被设置为固定存储区域，该固定存储区域位于与RFID芯片托盘（当提供时）相邻的RFID芯片托盘的盖子的平面以下，或者设置在弹出机构中由此RFID标签盒被集成到游戏桌中，使得当RFID标牌盒的顶表面被推动时，RFID标牌盒将弹出以提升堆叠的斑块或者喷墨打印纸以便进入。

7. 发明申请

WO2014165745A1 TREATMENT FOR CARDIAC CONDUCTANCE ABNORMALITIES 审中-公开
标题翻译：治疗心脏传导阻力异常
公开(公告)号：WO2014165745A1
公开(公告)日：2014-10-09
申请号：PCT/US2014/032957
申请日：2014-04-04
申请人： DREXEL UNIVERSITY , BULLINGA, John, R.
发明人： BULLINGA, John, R. , GUEZ, Allon
IPC分类号： A61N1/362
CPC分类号： A61N1/36114 , A61F2/82 , A61F2002/821
摘要： Methods and apparatuses are provided for treating cardiac conductive disorders that include implantation of a network of material that adaptively corrects the electrical conductivity of heart tissues and restores "normal" conductance. The methods and apparatuses disclosed herein involve the delivery of a material to a subject's heart in order to restore normal conductance in a minimally invasive, tunable, localized, and reversible manner, without artificial electrical stimulation.
摘要翻译：提供了用于治疗心脏传导障碍的方法和装置，包括植入自适应地校正心脏组织的电导率并恢复“正常”电导的材料网络。本文公开的方法和装置涉及将材料递送到受试者的心脏，以便以微创，可调，局部和可逆的方式恢复正常的电导，而无需人造电刺激。

8. 发明申请

WO2014165372A1 DIFFERENTIATION OF MACROMOLECULES AND ANALYSIS OF THEIR INTERNAL CONTENT IN SOLID-STATE NANOPORE DEVICES 审中-公开
标题翻译：大分子的分化及其在固体纳米装置中的内含物分析
公开(公告)号：WO2014165372A1
公开(公告)日：2014-10-09
申请号：PCT/US2014/031863
申请日：2014-03-26
申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人： DRNDIC, Marija , VENTA, Kimberly, Elizabeth , SHEMER, Gabriel
IPC分类号： C12Q1/68 , B32B5/16 , G01N27/26
CPC分类号： C12Q1/6869 , G01N27/44743 , G01N27/44791 , G01N33/48721
摘要： Provided are solid-state nanopore platforms for fast, electronic, label-free and high- resolution analysis of biomolecules.
摘要翻译：提供了用于生物分子的快速，电子，无标记和高分辨率分析的固态纳米孔平台。

9. 发明申请

WO2014150763A1 ANTI-PEROVSKITE SOLID ELECTROLYTE COMPOSITIONS 审中-公开
标题翻译：防静电固体电解质组合物
公开(公告)号：WO2014150763A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/024162
申请日：2014-03-12
申请人： LOS ALAMOS NATIONAL SECURITY, LLC
发明人： ZHAO, Yusheng , DAEMEN, Luc, Louis
IPC分类号： H01M10/0562
CPC分类号： H01M10/0562 , C01D15/00 , C01D15/04 , C01P2002/34 , C01P2002/72 , C01P2006/40 , H01G9/025 , H01G11/56 , H01M6/185 , H01M6/186 , H01M2300/0071 , Y02E60/13
摘要： Solid electrolyte antiperovskite compositions for batteries, capacitors, and other electrochemical devices have chemical formula Li3OA, Li(3-x)Mx/20A, Li(3-x)Nx/30A, or LiCOXzY(l-z), wherein M and N are divalent and trivalent metals respectively and wherein A is a B halide or mixture of halides, and X and Y are halides. Gel-liquid chemical systems are the electrolytes present in lithium batteries and other electrochemical devices. Gel-liquid chemical systems may include solvents, and the systems utilize solvated lithium ions for ion conduction.
摘要翻译：用于电池，电容器和其他电化学装置的固体电解质抗钙钛矿组合物具有化学式Li 3 O，Li（3-x）Mx / 20A，Li（3-x）Nx / 30A或LiCOXzY（lz），其中M和N是二价和三价金属，其中A是B卤化物或卤化物混合物，X和Y是卤化物。凝胶液化学系统是存在于锂电池和其他电化学装置中的电解质。凝胶液化学体系可能包括溶剂，系统利用溶剂化锂离子进行离子传导。

10. 发明申请

WO2014143320A2 WIDE BAND RECONFIGURABLE PLANAR ANTENNA WITH OMNIDIRECTIONAL AND DIRECTIONAL PATTERNS 审中-公开
标题翻译：宽带可重构平面天线，具有网络和方向图案
公开(公告)号：WO2014143320A2
公开(公告)日：2014-09-18
申请号：PCT/US2013/076816
申请日：2013-12-20
申请人： DREXEL UNIVERSITY , ADANT TECHNOLOGIES, INC.
发明人： PATRON, Damiano , DANDEKAR, Kapil, R. , PIAZZA, Daniele
IPC分类号： H01Q3/26
CPC分类号： H01Q3/24 , H01Q1/38 , H01Q3/44 , H01Q9/44 , H01Q21/205 , H01Q21/30
摘要： A planar reconfigurable antenna that is capable of generating omnidirectional and directional radiation patterns over a wide frequency band or over multiple frequency bands includes a substrate, one or more pairs of conductive elements on at least one side of the substrate, a common RF feed point, and respective switches that selectively connects one or all of the conductive elements to the common RF feed point. An omni-directional radiation pattern is generated when all of the conductive elements are connected to the common RF feed point, while a directional radiation pattern is generated when only a pair of conductive elements on opposite sides of the substrate are connected to the common RF feed point. In the directional radiation mode, the conductive elements that are not connected to the common RF feed point act as a reflector for other conductive elements that are connected to the common RF feed point.
摘要翻译：能够在宽频带或多个频带上产生全向和定向辐射图案的平面可重构天线包括衬底，衬底的至少一侧上的一对或多对导电元件，公共RF馈电点，以及各个开关，其选择性地将一个或所有导电元件连接到公共RF馈电点。当所有导电元件连接到公共RF馈电点时，产生全向辐射图，而当基板的相对侧上仅一对导电元件连接到公共RF馈电时产生定向辐射图点。在定向辐射模式中，未连接到公共RF馈电点的导电元件用作连接到公共RF馈电点的其它导电元件的反射器。

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