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    • 10. 发明申请
    • CONTINUOUS SYNTHESIS OF ISOOCTYL NITRATE IN A FLOW REACTOR
    • 在流动反应器中连续合成硝酸异氰酸酯
    • WO2015134703A1
    • 2015-09-11
    • PCT/US2015/018876
    • 2015-03-05
    • CORNING INCORPORATED
    • MA, BingSHEN, WeiWANG, YanhuaZHANG, Mo
    • C07C201/02C07C203/04
    • C07C201/02C07C203/04
    • A process for synthesizing isooctyl nitrate in a continuous flow reactor comprises flowing a H2SO4-HNO3 mixture within a flow reactor, flowing isooctyl alcohol into said flow reactor so as to mix the isooctyl alcohol with the H2SO4-HNO3 mixture and produce a reaction mixture stream flowing in said reactor, maintaining the reaction mixture stream flowing in said flow reactor at a reaction temperature within in the range -10° to 35°C inclusive, and wherein the residence time of the reaction mixture stream in the flow reactor is greater than or equal to 5 seconds and less than or equal to 40 seconds, and wherein the H2SO4 of the H2SO4-HNO3 mixture is H2SO4 having a concentration of in the range of 85 to 95% inclusive, more desirably 88 to 92% inclusive, most desirably of 90%.
    • 在连续流动反应器中合成硝酸异辛酯的方法包括使流动反应器内的H 2 SO 4 -HNO 3混合物流动,将异辛醇流入所述流动反应器中,以将异辛醇与H 2 SO 4 -HNO 3混合物混合并产生流动的反应混合物流 在所述反应器中,保持反应混合物流在所述流动反应器中流动的反应温度在-10℃至35℃的范围内,并且其中反应混合物流在流动反应器中的停留时间大于或等于 至5秒且小于或等于40秒,并且其中H 2 SO 4 -HNO 3混合物的H 2 SO 4为浓度为85-95%(含)的H 2 SO 4,更优选为88-92%,最优选为90 %。