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1. 发明申请

WO2023079258A1 LIQUID CRYSTAL DEVICES 审中-公开
公开(公告)号：WO2023079258A1
公开(公告)日：2023-05-11
申请号：PCT/GB2022/052563
申请日：2022-10-10
申请人： OXFORD UNIVERSITY INNOVATION LIMITED
发明人： SANDFORD O'NEILL, John , SALTER, Patrick , MORRIS, Stephen , ELSTON, Steve , BOOTH, Martin
IPC分类号： G02F1/1334 , G02F1/29
摘要： A liquid crystal device (400) is provided comprising: a liquid crystal layer having a thickness and comprising: a liquid crystal material; and a plurality of polymer structures (414a, 414b) comprising polymerised liquid crystal material. Each polymer structure (414a, 414b) is located at a different depth in the thickness of the liquid crystal layer. Electrodes are provided configured to apply an electric field to the liquid crystal layer. Each polymer structure (414a, 414b) has a different selected locked-in liquid crystal state.

2. 发明申请

WO2023052549A2 METHOD OF AND APPARATUS FOR CUTTING A SUBSTRATE OR PREPARING A SUBSTRATE FOR CLEAVING 审中-公开
公开(公告)号：WO2023052549A2
公开(公告)日：2023-04-06
申请号：PCT/EP2022/077195
申请日：2022-09-29
申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY
发明人： O'CONNOR, Gerard , FARID, Nazar , COLLINS, Adam , O'BRIEN, Cormac
IPC分类号： B23K26/00 , B23K26/0622 , B23K26/073 , B23K26/082 , B23K26/359 , B23K26/364 , B23K26/38 , B23K26/402 , B23K103/00 , B23K2103/52 , B23K2103/54 , B23K26/0006 , B23K26/0624 , B23K26/0732 , B23K26/0736
摘要： The present application relates to a method (100) for use in cutting a substrate or preparing a substrate for cleaving. The method (100) comprises: irradiating (102) the substrate with a plurality of pulses of a laser beam, the pulses having a pulse duration of less than a nanosecond and an elongate cross sectional spatial profile, and wherein the fluence of the plurality of pulses is controlled to be less than a single shot damage threshold fluence of the substrate; providing (104) relative movement between the laser beam and the substrate such that the plurality of pulses are arranged along a cutting path; and controlling (106) the relative movement such that each of the pulses is spatially overlapped with at least one other of the pulses along the cutting path. An apparatus having a laser system configured to perform the method (100) is also disclosed.

3. 发明申请

WO2023041932A1 BIOMARKERS 审中-公开
公开(公告)号：WO2023041932A1
公开(公告)日：2023-03-23
申请号：PCT/GB2022/052359
申请日：2022-09-16
申请人： THE UNIVERSITY OF BIRMINGHAM
发明人： MIDDLETON, Gary , PATEL, Akshay , BLACKBURN, Jonathan Michael , TAN, Ti-Myen
IPC分类号： G01N33/564 , G01N33/574 , C12Q1/6886
摘要： A method of providing a prognosis to a subject, the method comprising: i. providing a biological sample obtained from the subject; ii. determining the level of a panel of biomarkers comprising or consisting of SPATA 19, SPACA3, TSPY3, TCEA2, TSGA10, and LUZP4 in the sample; iii. comparing the level of the panel of biomarkers in the sample with a reference level of the same panel of biomarkers; iv. using the results from (iii) to provide a prognosis to the subject. More particularly, a method of providing a prognosis to a subject with cancer.

4. 发明申请

WO2023021336A2 RADIAL PLEATS FOR A FILTER 审中-公开
公开(公告)号：WO2023021336A2
公开(公告)日：2023-02-23
申请号：PCT/IB2022/000551
申请日：2022-08-19
申请人： PENTAIR PLC
发明人： SHISHODIA, Abhilash , VERMA, Sunil , SHARMA, Girish
IPC分类号： B01D29/21 , B01D29/23 , B01D46/52
摘要： A filter is provided. The filter comprises a plurality of radial pleats. Each of the plurality of radial pleats comprises a first section in a first plane and a second section in a second plane. Further, the first plane is offset with respect to the second plane.

5. 发明申请

WO2023007192A1 ATOMICALLY DISPERSED METAL CATALYST 审中-公开
公开(公告)号：WO2023007192A1
公开(公告)日：2023-02-02
申请号：PCT/GB2022/052018
申请日：2022-07-29
申请人： THE UNIVERSITY OF NOTTINGHAM
发明人： FERNANDES, Jesum Alves
IPC分类号： B01J21/18 , B01J23/42 , B01J23/46 , B01J23/755 , B01J23/75 , B01J35/02 , B01J35/00
摘要： A method for preparing an atomically dispersed metal catalyst, comprising: depositing atomically dispersed metal onto a support by magnetron sputtering to directly form a catalyst comprising metal particles, with mean diameter up to 1 nm, dispersed on the surface of the support, wherein the support is water insoluble.

6. 发明申请

WO2023007182A1 PROTEIN INTERACTION INHIBITORS 审中-公开
公开(公告)号：WO2023007182A1
公开(公告)日：2023-02-02
申请号：PCT/GB2022/052007
申请日：2022-07-29
申请人： THE UNIVERSITY OF BIRMINGHAM
发明人： RAYES, Julie , COLICCHIA, Martina
IPC分类号： C07K16/18 , C07K16/28 , A61P7/02 , A61P37/00 , A61K38/17 , A61K31/727
摘要： The invention relates to agents for use in preventing or reducing the interaction between S100 A8/A9 and GPIbα. Such agents are particularly for use in treating or preventing one or more inflammatory and/or thrombotic disease, such as cardiovascular diseases, chronic inflammatory diseases, infectious diseases and autoimmune diseases. An agent of the invention may be an antibody, a small molecule inhibitor, a peptide, a polypeptide, a recombinant protein, a nucleic acid, a T-cell receptor (TCR), an affibody, an aptamer, or a glycosaminoglycan.

7. 发明申请

WO2023285843A1 CUTTING RESISTANT MATERIAL 审中-公开
公开(公告)号：WO2023285843A1
公开(公告)日：2023-01-19
申请号：PCT/GB2022/051854
申请日：2022-07-18
申请人： ROYAL COLLEGE OF ART , RUSH, Diggory Philip
发明人： RUSH, Diggory Philip
IPC分类号： E05B15/16 , E05B67/00 , F16G13/12
摘要： A composite material (100) for resisting a cutting tool comprises a hollow casing (102). The composite material further comprises a mixture (104) disposed within the casing. The mixture comprises an intumescent material (104a). The composite material further comprises a ductile material (104b). In response to heat generated during cutting, the intumescent material is configured to expand to urge the ductile material against the cutting tool. A chain link (300) comprising the composite material is also provided. A security device (600) comprising the composite material or the chain link is further provided. A method of manufacturing a composite material for resisting a cutting tool is provided. The method comprises disposing a mixture of an intumescent material and a ductile material in a hollow casing.

8. 发明申请

WO2023285841A1 PARTICLE CHARACTERISATION METHOD AND APPARATUS 审中-公开
公开(公告)号：WO2023285841A1
公开(公告)日：2023-01-19
申请号：PCT/GB2022/051852
申请日：2022-07-18
申请人： MALVERN PANALYTICAL LIMITED
发明人： MARWICK, Daniel , MAZILU, Michael
IPC分类号： G06F17/16 , G02B5/00 , G06N3/00
摘要： A method of preparing a representative particle size and refractive index database, for use in determining the size and refractive index of one or more particles within a sample (8) is disclosed. A method of determining the size and refractive index of one or more particles contained within a sample (8) is also disclosed. The size and refractive index determination method comprises: obtaining a measured scattering pattern for said particles, the measured scattering pattern comprising a number of data dimensions; reducing, using a processor (14), the number of data dimensions associated with the measured scattering pattern to obtain dimensionally reduced measured data; comparing, using the processor, the dimensionally reduced measured data with a representation of reference scattering patterns, said reference scattering patterns corresponding to particles having a range of known sizes and refractive indices; and selecting, as the size and refractive index of the one or more particles contained within the sample, the known size and refractive index corresponding to the representation of the reference scattering patterns which most closely corresponds to the dimensionally reduced measured data.

9. 发明申请

WO2023285839A1 NERVE LABEL 审中-公开
公开(公告)号：WO2023285839A1
公开(公告)日：2023-01-19
申请号：PCT/GB2022/051847
申请日：2022-07-18
申请人： UCL BUSINESS LTD
发明人： YAGHINI, Elnaz , MACROBERT, Alexander John , PHILLIPS, James
IPC分类号： A61K49/00
摘要： The invention relates to a method of visualising a peripheral nerve, the method comprising contacting the nerve with a 5-aminolevulinate or a derivative thereof.

10. 发明申请

WO2023275853A1 LID 审中-公开
公开(公告)号：WO2023275853A1
公开(公告)日：2023-01-05
申请号：PCT/IB2022/056189
申请日：2022-07-04
申请人： DIP N SIV LIMITED
发明人： SWALLOW, Darryl
IPC分类号： B44D3/12 , B44D3/14 , B44D3/123 , B44D3/127 , B44D3/128
摘要： A lid (10) for a paint container is described. In one embodiment said lid comprise a sieve (32) for filtering paint to or from a storage container and the paint container, an opening (30) for accessing paint within the paint container; and attachment means (40) releasably biasing the lid against the paint container.

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