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    • 10. 发明申请
    • ALLERGY INHIBITOR COMPOSITIONS AND KITS AND METHODS OF USING THE SAME
    • 过敏抑制剂组合物和用途及其使用方法
    • WO2007076084A2
    • 2007-07-05
    • PCT/US2006/049161
    • 2006-12-22
    • CHINA AGRICULTURAL UNIVERSITYWYETHWANG, BinJIN, HualiKANG, YouminCHU, Hsien-JueNG, Kaleung
    • WANG, BinJIN, HualiKANG, YouminCHU, Hsien-JueNG, Kaleung
    • C12N15/86
    • A61K39/35A61K39/0003A61K39/0005A61K39/0008A61K2039/53A61K2039/57
    • Compositions and kits for inhibiting an allergic response against an allergenic protein are disclosed. The compositions comprise a eukaryotic cell expression vector containing nucleotide sequences encoding an allergenic protein or a polypeptide that comprises an antigenic epitope of said allergenic protein; and an allergenic protein or a polypeptide that comprises an antigenic epitope of the allergenic protein. The kits comprise a first container which comprises a eukaryotic cell expression vector containing nucleotide sequences encoding an allergenic protein or a polypeptide that comprises an antigenic epitope of the allergenic protein and a second container which comprises an allergenic protein or a polypeptide that comprises an antigenic epitope of said allergenic protein. Compositions and kits for inhibiting an allergic response against an flea allergenic protein; a feline allergenic protein; a canine allergenic protein; a dust mite allergenic protein; a peanut allergenic protein; a Japanese cedar allergenic protein; and a blomia tropicalis allergenic protein are disclosed. Methods if using such compositions and kits are also disclosed.
    • 公开了用于抑制对变应原性蛋白质的过敏反应的组合物和试剂盒。 组合物包含含有编码过敏原蛋白或包含所述变应原蛋白的抗原表位的多肽的核苷酸序列的真核细胞表达载体; 以及包含过敏原蛋白的抗原表位的变应原蛋白或多肽。 试剂盒包括第一容器,其包含含有编码过敏原蛋白的核苷酸序列的真核细胞表达载体或包含过敏原蛋白的抗原表位的多肽,第二容器包含过敏原蛋白或包含抗原决定簇的多肽 表示过敏原蛋白。 用于抑制针对跳蚤过敏原蛋白质的过敏反应的组合物和试剂盒; 猫过敏原蛋白; 犬过敏蛋白; 尘螨变应原蛋白; 花生过敏蛋白; 日本雪松过敏蛋白; 并且公开了热带炎热带炎性过敏蛋白。 还公开了使用这些组合物和试剂盒的方法。