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    • 77. 发明申请
    • NON-IRRITATING FORMULATION AND METHOD FOR THE INTRADERMAL DELIVERY OF SUBSTANCES
    • 非物质配制和方法用于物质输送
    • WO2007050127A1
    • 2007-05-03
    • PCT/US2006/020909
    • 2006-05-30
    • SCHUR, Henry, B.
    • SCHUR, Henry, B.
    • A61K9/14
    • A61K8/925A61K8/8176A61K8/922A61K8/97A61K9/06A61K9/7023A61K2800/75A61Q19/00A61Q19/08
    • This invention describes a composition of matter to facilitate intra-dermal delivery of a great variety of active substances, especially including high molecular weight cosmeceuticals . Also disclosed is a method of forming the composition of matter and applying topically to patients, especially using a cream or patch. The active substance is initially combined with a biopolymer, which combination, is subsequently linked to a base formulation whereby the base formulation aids in the intra-dermal delivery of the active substance without the skin irritation limitations of other formulations and dermal transmitting methods. The use of a combination of natural herbal, vegetable and animal products combined in this invention with biopolymers permits molecules of higher molecule weight to penetrate into the skin in a bioactive form by passive delivery means. The invention includes a product for, the improvement of skin health and wrinkle reduction.
    • 本发明描述了一种物质的组合物,其促进大量各种活性物质的皮内递送,特别是包括高分子量药妆。 还公开了形成物质组合物并局部施用于患者,特别是使用霜剂或贴剂的方法。 活性物质最初与生物聚合物组合,该组合随后与碱性制剂连接,由此基础制剂有助于活性物质的皮内递送,而不会引起其他制剂和皮肤传播方法的皮肤刺激限制。 将本发明的天然草药,植物和动物产品与生物聚合物的组合的使用允许较高分子量的分子通过被动递送装置以生物活性形式渗入皮肤。 本发明包括用于改善皮肤健康和减少皱纹的产品。