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61. 发明申请

WO2006130771A2 FOUR-DIMENSIONAL VOLUME OF INTEREST 审中-公开
标题翻译：四维感兴趣的体积
公开(公告)号：WO2006130771A2
公开(公告)日：2006-12-07
申请号：PCT/US2006021291
申请日：2006-06-01
申请人： ACCURAY INC , WANG HONGWU , DOOLEY JOHN R , WEST JAY B
发明人： WANG HONGWU , DOOLEY JOHN R , WEST JAY B
CPC分类号： G06T19/00 , A61N5/103 , A61N5/1037 , G06T7/0012 , G06T7/20 , G06T15/08 , G06T2207/10076 , G06T2207/30096
摘要： A method and apparatus for a four-dimensional volume of interest is described.
摘要翻译：描述了一种四维感兴趣体积的方法和装置。

62. 发明申请

WO2006039586A3 NON-LINEAR CORRELATION MODELS FOR INTERNAL TARGET MOVEMENT 审中-公开
标题翻译：用于内部目标运动的非线性相关模型
公开(公告)号：WO2006039586A3
公开(公告)日：2006-06-08
申请号：PCT/US2005035361
申请日：2005-09-30
申请人： ACCURAY INC , SAYEH SOHAIL
发明人： SAYEH SOHAIL
IPC分类号： A61B6/00 , A61N5/00
CPC分类号： A61B5/1127 , A61B5/113 , A61B6/4458 , A61N5/1037 , A61N5/1049 , A61N5/1064 , A61N5/1067 , A61N5/107 , A61N2005/1061
摘要： A method and apparatus to track non-linear internal target movement based on movement of an external marker.
摘要翻译：基于外部标记的移动跟踪非线性内部目标移动的方法和装置。

63. 发明申请

WO2006039009A2 DYNAMIC TRACKING OF MOVING TARGETS 审中-公开
标题翻译：动态目标的动态跟踪
公开(公告)号：WO2006039009A2
公开(公告)日：2006-04-13
申请号：PCT/US2005/030081
申请日：2005-08-22
申请人： ACCURAY INC. , THOMSON, Euan , DOOLEY, John, Robinson , KUDUVALLI, Gopinath , WANG, James , EARNST, Eric , RAANES, Chris
发明人： THOMSON, Euan , DOOLEY, John, Robinson , KUDUVALLI, Gopinath , WANG, James , EARNST, Eric , RAANES, Chris
IPC分类号： A61B5/05
CPC分类号： A61N5/1037 , A61B5/055 , A61B5/113 , A61B6/032 , A61B6/037 , A61B6/12 , A61B6/5217 , A61B34/20 , A61B90/36 , A61B2017/00694 , A61B2034/105 , A61B2034/2065 , A61B2090/101 , A61B2090/367 , A61B2090/3762 , A61N5/1039 , A61N5/1049 , A61N5/1064 , A61N5/1067 , A61N2005/1052 , A61N2005/1055 , A61N2005/1061 , A61N2005/1062
摘要： Treatment targets such as tumors or lesions, located within an anatomical region that undergoes motion (which may be periodic with cycle P), are dynamically tracked. A 4D mathematical model is established for the non-rigid motion and deformation of the anatomical region, from a set of CT or other 3D images. The 4D mathematical model relates the 3D locations of part(s) of the anatomical region with the targets being tracked, as a function of the position in time within P. Using fiducialless non-rigid image registration between pre-operative DRRs and intra-operative x-ray images, the absolute position of the target and/or other part(s) of the anatomical region is determined. The cycle P is determined using motion sensors such as surface markers. The radiation beams are delivered using: 1) the results of non-rigid image registration; 2) the 4D model; and 3) the position in time within P.
摘要翻译：动态跟踪位于经历运动的解剖区域（可能与周期P周期性）的肿瘤或病变的治疗靶点。建立了一个4D数学模型，用于从一组CT或其他3D图像中解剖区域的非刚性运动和变形。 4D数学模型将解剖区域的部分的3D位置与正在跟踪的目标相关联，作为P内时间位置的函数。使用手术前DRR和手术之间的无基底非刚性图像配准 x射线图像，确定目标和/或解剖区域的其他部分的绝对位置。周期P使用诸如表面标记的运动传感器来确定。使用以下方式传送辐射束：1）非刚性图像配准的结果; 2）4D模型; 和3）在时间内的位置。

64. 发明申请

WO2005030330A1 TARGET TRACKING METHOD AND APPARATUS FOR RADIATION TREATMENT PLANNING AND DELIVERY 审中-公开
标题翻译：目标跟踪方法和放射治疗计划和交付的设备
公开(公告)号：WO2005030330A1
公开(公告)日：2005-04-07
申请号：PCT/IB2004/051741
申请日：2004-09-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , U.S. PHILIPS CORPORATION , STECKNER, Michael, C. , BOERNERT, Peter , NEHRKE, Kay
发明人： STECKNER, Michael, C. , BOERNERT, Peter , NEHRKE, Kay
IPC分类号： A61N7/02
CPC分类号： A61B17/2256 , A61B5/055 , A61B5/1127 , A61B34/20 , A61B90/36 , A61B2017/00699 , A61B2034/105 , A61B2034/2051 , A61B2034/2055 , A61B2034/2072 , A61B2090/374 , A61B2090/3937 , A61B2090/3995 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N7/02 , A61N2005/1055
摘要： A target treatment apparatus for treating a target region (130) within a subject (140) is provided. The apparatus includes an MRI apparatus (100) for generating MR images during an MR scan of the subject disposed within an examination region (110). The apparatus further includes an MRI localizer (150) for receiving the image data from the MRI apparatus wherein the target (130) is localized and a reference marker localizer (160, 160') for non-invasively receiving reference data from a plurality of reference points disposed in proximity to the target wherein the reference points are localized. A tracking processor (300) is also included in the apparatus for receiving localized data from the MRI localizer wherein a relationship between the reference markers and the target region is generated.
摘要翻译：提供了一种用于治疗受试者（140）内的目标区域（130）的靶处理装置。该装置包括用于在设置在检查区域（110）内的对象的MR扫描期间产生MR图像的MRI装置（100）。该装置还包括用于从MRI装置接收图像数据的MRI定位器（150），其中所述目标（130）被定位，以及用于从多个参考中非侵入地接收参考数据的参考标记定位器（160,160'）设置在目标附近的点，其中参考点被定位。跟踪处理器（300）也包括在用于从MRI定位器接收本地化数据的装置中，其中生成参考标记和目标区域之间的关系。

65. 发明申请

WO2004112903A1 APPARATUS USING SYNCHRONIZED BREATHING TO TREAT TISSUE SUBJECT TO RESPIRATORY MOTION 审中-公开
标题翻译：使用同步呼吸治疗呼吸运动的装置
公开(公告)号：WO2004112903A1
公开(公告)日：2004-12-29
申请号：PCT/US2004/018888
申请日：2004-06-10
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION , ZHANG, Tiezhi , PALIWAL, Bhudatt, R.
发明人： ZHANG, Tiezhi , PALIWAL, Bhudatt, R.
IPC分类号： A61N5/10
CPC分类号： A61B6/541 , A61B5/087 , A61B5/1135 , A61N5/1037 , A61N5/1042 , A61N5/1048 , A61N5/1064
摘要： Radiation treatment of the lung or surrounding tissue during continuous breathing is made possible by preparing a treatment plan linked to motion phase and then synchronizing the plan to motion phase as the patient follows a regular breathing schedule.
摘要翻译：连续呼吸期间肺或周围组织的放射治疗可以通过准备与运动相关联的治疗计划，然后当患者遵循常规呼吸计划时将计划同步到运动阶段成为可能。

66. 发明申请

WO99042034A3 DEVICE FOR THE SYNCHRONIZATION WITH PHYSIOLOGICAL CYCLES 审中-公开
标题翻译：与生理循环同步的设备
公开(公告)号：WO99042034A3
公开(公告)日：1999-10-14
申请号：PCT/US1999/003239
申请日：1999-02-16
IPC分类号： A61B5/05 , A61B5/0402 , A61B6/00 , A61N5/10
CPC分类号： A61B6/541 , A61B5/7285 , A61B6/507 , A61N5/1037 , A61N5/1064
摘要： Method and apparatus for coordinating a medical treatment or diagnostic procedure with at least one physiological cycle of a patient, e.g. by synchronizing a ventilator with an X-ray machine to ensure that an X-ray chest image is taken at peak insufflation of the patient. The subject invention also relates to other medical procedures including, but not limited to, cardiac output measurement, chest imaging, inhalation therapy, oxygen delivery, blood pressure measurement, extracorporeal shock wave lithotripsy and pulse oximeter optoplethysmograms.
摘要翻译：用于使患者的至少一个生理周期协调医疗或诊断程序的方法和装置，例如，通过使呼吸机与X光机同步，以确保在患者的峰值吹风时拍摄X射线胸部图像。本发明还涉及其它医学过程，包括但不限于心输出量测量，胸部成像，吸入治疗，氧气输送，血压测量，体外冲击波碎石术和脉搏血氧计光学体积描记图。

67. 发明申请

WO9942034A2 DEVICE FOR THE SYNCHRONIZATION WITH PHYSIOLOGICAL CYCLES 审中-公开
标题翻译：与生理循环同步的设备
公开(公告)号：WO9942034A2
公开(公告)日：1999-08-26
申请号：PCT/US9903239
申请日：1999-02-16
申请人： UNIV FLORIDA
发明人： LAMPOTANG SAMSUN , LANGEVIN PAUL B
IPC分类号： A61B5/05 , A61B5/0402 , A61B6/00 , A61N5/10
CPC分类号： A61B6/541 , A61B5/7285 , A61B6/507 , A61N5/1037 , A61N5/1064
摘要： The subject invention pertains to a novel method and apparatus for improving the efficacy of a medical treatment or diagnostic procedure by coordinating such treatment or procedure with at least one physiological cycle of a patient. In a specific embodiment, the subject invention pertains to a novel method of coordinating a chest X-ray with a patient's ventilatory cycle. In a specific example, this invention concerns a novel device for interfacing a ventilator and an X-ray machine to ensure that an X-ray chest image can be taken at peak insufflation of the patient. The subject invention also relates to other medical procedures including, but not limited to, cardiac output measurement, chest imaging, inhalation therapy, oxygen delivery, blood pressure measurement, extracorporel shock wave lithotripsy, and pulse oximeter optoplethysmograms. By coordinating certain medical treatments and diagnostic procedures with a patient's physiological cycle(s), the subject invention improves the quality of medical care received by the patient.
摘要翻译：本发明涉及一种用于通过将这种治疗或程序与患者的至少一个生理周期协调来改善药物治疗或诊断程序的功效的新型方法和装置。在一个具体实施方案中，本发明涉及一种协调胸部X射线与患者通气循环的新方法。在具体实例中，本发明涉及一种用于与呼吸机和X射线机接口的新型装置，以确保在患者的最大灌注时能够摄取X射线胸部图像。本发明还涉及其他医学过程，包括但不限于心输出量测量，胸部成像，吸入治疗，氧气输送，血压测量，体外冲击波碎石术和脉搏血氧计光学血压图。通过与患者的生理周期协调某些医疗和诊断程序，本发明提高了患者接受的医疗护理质量。

68. 发明申请

WO2019127443A1 SYSTEM AND METHOD FOR SYNCHRONOUS MOTION OPTIMIZATION OF DEVICE WITH MOVING COMPONENTS 审中-公开
公开(公告)号：WO2019127443A1
公开(公告)日：2019-07-04
申请号：PCT/CN2017/120051
申请日：2017-12-29
申请人： SHENZHEN UNITED IMAGING HEALTHCARE CO., LTD.
发明人： LI, Zihan , BOSE, Supratik , MA, Boqi
IPC分类号： A61B6/00
CPC分类号： A61N5/1031 , A61N5/1036 , A61N5/1037 , A61N5/1047 , G05D3/20
摘要： Systems and methods for synchronous motion optimization of device of moving components are provided. The methods may include obtaining positions of multiple components of a system; determining, based on the positions, a velocity of each component at each position; determining, based on the velocity of each component, a minimum duration for each component to traverse each segment between two sequential positions; determining, based on the minimum duration for each component to traverse each segment, an optimized duration corresponding to each segment; and determining, based on the optimized duration corresponding to each segment, motion parameters of each component in each segment, the motion parameters of each component in each segment forming the control plan of the system.

69. 发明申请

WO2018194297A1 치료기 제어 시스템 및 방법 审中-公开
公开(公告)号：WO2018194297A1
公开(公告)日：2018-10-25
申请号：PCT/KR2018/003945
申请日：2018-04-04
申请人： 사회복지법인 삼성생명공익재단
发明人： 주상규
IPC分类号： A61N5/10
CPC分类号： A61N5/1001 , A61N5/1037 , A61N5/1065 , A61N2005/1072 , A61N2005/1074
摘要： 본 발명의 일 실시예는 환자에게 방사선을 조사하는 치료기를 제어하는 치료기 제어 방법에 있어서, 환자의 자세와 환자의 주변배경에 대한 정보를 포함하고, 복수개의 픽셀로 구성된 입력영상 신호를 일정한 시간 간격을 두고 획득하는 단계와, 입력영상 신호를 디지털 변환하여 복수개의 픽셀 각각의 명암 강도에 대한 정보를 포함하는 입력영상 데이터를 생성하는 단계와, 입력영상 데이터의 변화가 기설정된 변화 임계값을 벗어나는지 여부를 분석하여 기준영상 데이터를 생성하는 단계와, 가장 최근에 생성된 입력영상 데이터와 기준영상 데이터의 차이가 기설정된 움직임 임계값을 벗어나는지 여부에 따라 움직임이 있는 참 픽셀과 움직임이 없는 거짓 픽셀을 포함하는 움직임 데이터를 생성하는 단계와, 움직임 데이터를 기반으로 복수개의 픽셀 중 참 픽셀의 비율이 기설정된 제어 임계값을 벗어나는지 여부에 따라 치료기의 방사선 조사를 제어하는 단계를 포함하는 치료기 제어 방법을 개시한다.

70. 发明申请

WO2017174189A1 TIME OPTIMIZED RADIATION TREATMENT 审中-公开
标题翻译：时间最优化的辐射治疗
公开(公告)号：WO2017174189A1
公开(公告)日：2017-10-12
申请号：PCT/EP2017/000420
申请日：2017-04-04
申请人： VARIAN MEDICAL SYSTEM PARTICLE THERAPY GMBH
发明人： GÖBEL, Holger , HUTH, Isabel
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/103 , A61N5/1037 , A61N5/1039 , A61N5/1043 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N5/1071 , A61N5/1077 , A61N2005/1087
摘要： In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.
摘要翻译：在一个实施例中，一种方法包括：接收与旨在照射靶组织的质子或离子束治疗的治疗计划有关的治疗信息; 接收涉及质子或离子束治疗中涉及的一个或多个机器的一个或多个限制的机器限制信息; 基于治疗信息和机器限制信息确定质子或离子束的时间优化的束电流，其中时间优化的束电流最小化将所需数量的监视器单元递送到多个其中所述多个点中的每一个是所述目标组织的特定区域; 并将时间优化的束流提供给特定区域。

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