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61. 发明申请

WO1996004015A1 MICROPARTICLE PREPARATIONS FOR CLEARING BLOOD-DISSOLVED SUBSTANCES 审中-公开
标题翻译：微粒筹备工作消除血液中溶解的物质
公开(公告)号：WO1996004015A1
公开(公告)日：1996-02-15
申请号：PCT/EP1995002886
申请日：1995-07-21
申请人： SCHERING AKTIENGESELLSCHAFT , WEITSCHIES, Werner , HELDMANN, Dieter , BUNTE, Thomas , SPECK, Ulrich
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： A61K47/48
CPC分类号： A61K51/1241 , A61K9/1271 , A61K9/167 , A61K39/44
摘要： Microparticle preparations are used to clear kidney-impassable substances from blood.
摘要翻译：本发明涉及使用微颗粒药剂的用于从血液消除非共同肾物质。

62. 发明申请

WO1995032212A1 PROCESS FOR PRODUCING ARABINO-NUCLEOSIDES 审中-公开
标题翻译：用于生产ARABINONUKLEOSIDEN
公开(公告)号：WO1995032212A1
公开(公告)日：1995-11-30
申请号：PCT/EP1995001343
申请日：1995-04-13
申请人： SCHERING AKTIENGESELLSCHAFT , HUMMEL-MARQUARDT, Heidi , KENNECKE, Mario , WEBER, Alfred , SCHMITZ, Thomas , TILSTAM, Ulf , NICKISCH, Klaus
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： C07H19/19
CPC分类号： C07H19/16 , C12P19/40
摘要： The invention relates to a process for producing arabino-nucleosides of general formula (I), in which X is a hydrogen atom or a fluorine atom, from triacetates of general formula (II), in which X has the meaning given above and the groups Ac are acetyl groups, in which an esterase or lipase is caused to act on these compounds.
摘要翻译：本发明涉及一种用于制备Arabinonukleosiden通式（I）的方法，其中X表示氢原子或氟原子，（II），其中X如以上所定义和该基团Ac各乙酰基，通式三乙其的特征在于，被允许作用于这些化合物是酯酶或脂肪酶。

63. 发明申请

WO1995026730A1 COMBINED HORMONAL CONTRACEPTION PHARMACEUTICAL PREPARATION 审中-公开
标题翻译：药物组合制剂用于激素避孕
公开(公告)号：WO1995026730A1
公开(公告)日：1995-10-12
申请号：PCT/EP1995001190
申请日：1995-03-30
申请人： SCHERING AKTIENGESELLSCHAFT , LACHNIT, Ursula , DÜSTERBERG, Bernd , SPONA, Jürgen
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： A61K31/57
CPC分类号： A61K31/565 , A61K31/567 , A61K31/57 , Y10S514/843 , A61K2300/00
摘要： A combined pharmaceutical preparation has two hormonal components for sequential oral administration separately conditioned in a packaging unit that consist of a number of daily dosing units separately conditioned in and individually removable from the packaging unit. The first hormonal component contains as active hormonal substance a dose of oestrogen combined with a dose of a gestagen preparation that is at least sufficient to inhibit ovulation. The second hormonal component contains as active hormonal substance only an oestrogen preparation. The first hormonal component consists of 23 or 24 daily units and the second hormonal component of 4 to 10 daily units. The total number of hormonal daily units equals the total number of days in the desired cycle, but at least 28 days. This combined female contraception preparation allows the oestrogen content in each individual dosing unit to be reduced as much as possible and also has a low total hormonal content per administration cycle, while ensuring a high contraceptive dependability, a low incidence of follicle development, a flawless cycle control and a reliable prevention of spotting and other undesirable side effects.
摘要翻译：本发明描述中的包装单元有两个的药物组合制剂组装空间上分离的，对于某些激素组分的时间顺序的口服给药，它们各自从多个间隔开并除去单独容纳在包装单元日剂量单位，其中第一激素组分作为激素的活性成分仅在组合含有雌激素和至少抑制排卵足够剂量，孕激素制剂，并且所述第二激素组分作为激素活性成分的雌激素制剂，其中第一激素成分23或24和第二激素组分包含4至10个每日单位和激素每日单元的总数等于总数目是所需的，但至少28天周期长的日子。这种组合产品，其用于雌性节育，允许在每个剂量单位的最低可能的雌激素含量，并且还具有每次给药周期，高的避孕可靠性，卵泡发育，与中间出血和不希望的副作用的可靠避免完美周期控制的低发生率较低的总激素含量。

64. 发明申请

WO1995022322A1 SEXUAL STEROID-CONTAINING TRANSDERMAL THERAPEUTIC SYSTEMS 审中-公开
标题翻译：透皮治疗系统含有性爱相关STEROIDS
公开(公告)号：WO1995022322A1
公开(公告)日：1995-08-24
申请号：PCT/EP1995000483
申请日：1995-02-09
申请人： SCHERING AKTIENGESELLSCHAFT , LIPP, Ralph , GÜNTHER, Clemens , RIEDL, Jutta , TÄUBER, Ulrich
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： A61K09/70
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61K31/565 , A61K31/57 , A61K47/26
摘要： Transdermal therapeutic systems are disclosed that contain sexual steroids and, if required, penetration reinforcing agents and crystallisation inhibitors, with the exception of systems that contain non-fluid, active substance-containing gel phases or 3-keto-desorgestrel. These transdermal therapeutic systems are characterised in that they contain dimethylisosorbide.
摘要翻译：包括性激素的透皮治疗系统，并且如果合适的话，渗透增强剂和结晶抑制剂被描述，其特征在于，它们包含含有与含有活性物质不流动的凝胶相或3-酮 - 地索高诺系统异常二甲基异山梨醇。

65. 发明申请

WO1995020981A1 AGENT FOR MARKING BODILY TISSUES 审中-公开
标题翻译：手段身体组织的视标
公开(公告)号：WO1995020981A1
公开(公告)日：1995-08-10
申请号：PCT/EP1995000123
申请日：1995-01-13
申请人： SCHERING AKTIENGESELLSCHAFT , HEYWANG-KÖBRUNNER, Sylvia , WEITSCHIES, Werner , SPECK, Ulrich , FRITZSCH, Thomas
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： A61K49/00
CPC分类号： A61K49/04 , A61B90/39 , A61B2090/3933 , A61B2090/3937 , A61B2090/3954 , A61K49/06 , A61K49/22 , A61K49/223
摘要： The invention relates to the use of coloured NMR, X-ray or possibly dye-containing ultrasonic-image-producing substances for marking bodily tissues.
摘要翻译：本发明涉及使用彩色NMR，X-射线或任选的超声成像物质用于标记身体组织含染料。

66. 发明申请

WO1995014678A1 1,4,7,10-TETRAAZACYCLODODECANE DERIVATIVES, THEIR USE, PHARMACEUTICALS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION 审中-公开
标题翻译： 1,4,7,10-四衍生物，其用途，制药遏制和方法及其
公开(公告)号：WO1995014678A1
公开(公告)日：1995-06-01
申请号：PCT/EP1994003718
申请日：1994-11-10
申请人： SCHERING AKTIENGESELLSCHAFT , HILGER, Christoph-Stephan , EBERT, Wolfgang , LEE-VAUPEL, Mary , PLATZEK, Johannes , CONRAD, Jürgen , RADÜCHEL, Bernd
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： C07D257/02
CPC分类号： C07D257/02 , A61K49/06 , Y10S514/836
摘要： The invention relates to novel 1,4,7,10-tetraazacyclododecane derivatives of formula (I) in which R represents, mutually independently, H, a C1-C6 alkyl radical or a metal ion equivalent, R represents, mutually independently, H, a methyl or an ethyl radical, X is a direct bond or a C1-C10 alkylene group or a C2-C23 alkylene group interrupted by one or more oxygen atoms, in which the alkyl radicals and alkylene groups are optionally substituted by one or more hydroxy and/or lower alkoxy radicals and/or contain one or more carbonyl functions, and V is a radical of formula (II), their metal complexes, pharmaceuticals containing these compounds, their use in diagnosis and therapy and processes for producing these compounds and agents.
摘要翻译：本发明涉及下式的新1,4,7,10-四衍生物（I），其中R <1>各自独立地是H，一个C1-C6烷基或金属离子等价物，R <2>独立地表示H，一个甲基或乙基，X表示直接键合或一个C1-C10亚烷基或由一个或多个氧原子的C2-C23亚烷基，其中所述烷基和亚烷基任选地被一个或多个羟基和/或低级烷氧基的基团取代的中断被取代的和/或包含一个或多个羰基官能团，并且V是下式基团（II），它们的金属络合物，含有这些化合物的药剂，其在用于制备这些化合物和试剂的诊断和治疗和方法中使用。

67. 发明申请

WO1995006634A1 NEW 9-CHLORO-PROSTAGLANDIN DERIVATIVES 审中-公开
标题翻译：新的9-氯前列腺素衍生物
公开(公告)号：WO1995006634A1
公开(公告)日：1995-03-09
申请号：PCT/EP1994002855
申请日：1994-08-29
申请人： SCHERING AKTIENGESELLSCHAFT , BUCHMANN, Bernd , SKUBALLA, Werner
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： C07C405/00
CPC分类号： B82Y5/00 , A61K47/6951 , C07C405/00 , C07C405/0025
摘要： 9-chloro-prostaglandin derivatives having the formula (I), in which X stands for oxygen or CH2, R stands for hydrogen or straight or branched chain alkyl with 1-6 C atoms and A stands for trans-CH=CH- or -CH2-CH2-, are disclosed, as well as their salts with physiologically neutral bases, when R stands for hydrogen, their clathrates with alpha -, beta - or gamma -cyclodextrin, a process for preparing the same and their pharmaceutical use.
摘要翻译：本发明涉及式（I）其中X为氧或9-氯前列腺素衍生物CH2，R <1>是具有1-6个C原子并且A是反式-CH = CH-或-CH 2氢或直链或支链烷基意味着-CH 2 - ，以及它们与生理上可耐受的碱的盐，当R <1>是氢和它们的具有α-笼形物 - ，β - 或γ-环糊精，其制备和它们的药物用途。

68. 发明申请

WO1995006009A1 DEVICE FOR PURIFYING WASTE WATER OR GROUND WATER AND USE THEREOF 审中-公开
标题翻译：设备用于清洗废水或地下水及其用途
公开(公告)号：WO1995006009A1
公开(公告)日：1995-03-02
申请号：PCT/EP1994002495
申请日：1994-07-29
申请人： SCHERING AKTIENGESELLSCHAFT , DONNER, Christoph , SOKOLOWSKY, Stephan , REINKE, Lothar , TILL, Frank
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： C02F03/00
CPC分类号： C02F3/085 , C02F1/285 , C02F3/02 , Y02W10/15
摘要： The invention pertains to a device for purifying waste water or groundwater contaminated with biodegradable matter or organic substances that can be removed by adsorption/desorption, characterized by a) a biodegrading fermentation system, b) an absorber system upstream or downstream therefrom, containing a regenerative polymer adsorbent, a feed line and an outlet as well as a steam feed and one drain pipe each for the desorbate and the purified water, and c) a returning line connecting the output of the downstream system to the input of the upstream system.
摘要翻译：一种用于净化废水或地下水，其由可生物降解的和通过吸附/解吸污染可分离有机物质，进行了说明，这是由一个特征在于一个服务于该生物降解发酵系统）设备，b）一种本上游或下游提供再生聚合物吸附剂吸收器系统，其设置有入口和出口并具有蒸汽供应和每个具有用于解吸的排出管，和净化水，和c）在下游系统的输出连接到上游系统的输入端的返回管线。

69. 发明申请

WO1994025469A1 QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS 审中-公开
标题翻译：新CHINOXALINDIONDERIVATIVE，生产和使用毒品
公开(公告)号：WO1994025469A1
公开(公告)日：1994-11-10
申请号：PCT/DE1994000493
申请日：1994-04-28
申请人： SCHERING AKTIENGESELLSCHAFT , HUTH, Andreas , TURSKI, Lechoslaw
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： C07F09/6509
CPC分类号： C07D231/12 , C07D233/56 , C07D241/44 , C07D249/08 , C07D401/12 , C07D403/06 , C07F9/650994 , C07F9/65583
摘要： Described are compounds of formula (I) in which R , R , R , R and R are as defined in the application, plus their preparation and their use in drugs.

70. 发明申请

WO1994022898A1 NEW GLUCOCORTICOIDS 审中-公开
标题翻译：新糖皮质激素
公开(公告)号：WO1994022898A1
公开(公告)日：1994-10-13
申请号：PCT/EP1994000937
申请日：1994-03-24
申请人： SCHERING AKTIENGESELLSCHAFT , ZENTEL, Hans, Joachim , TÖPERT, Michael , LAURENT, Henry , BRUMBY, Thomas , ESPERLING, Peter
发明人： SCHERING AKTIENGESELLSCHAFT
IPC分类号： C07J43/00
CPC分类号： C07J41/005 , C07J43/003
摘要： Glucocorticoids have the general formula (I): R-Val-O-GC, in which O-GC stands for the rest of an anti-inflammatory 21-hydroxycorticoid, Val stands for a valine residue located at the 21st position of the corticoid and R stands for a hydrogen atom or for a hydrocarbon residue having up to 32 carbon atoms and if required substituted by hydroxy groups, amino groups, oxo groups and/or halogen atoms and/or interrupted by oxygen atoms, SO2 groups and/or NH groups. Also disclosed are the salts of said corticoids.

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