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51. 发明申请

WO2013045443A1 MEASUREMENT OF LACTIC ACID IN BIOLOGICAL FLUIDS 审中-公开
标题翻译：生物流体中酸乳酸的测定
公开(公告)号：WO2013045443A1
公开(公告)日：2013-04-04
申请号：PCT/EP2012/068867
申请日：2012-09-25
申请人： BRAMANTI, Emilia , ZUCCHINI, Fabrizio , ONOR, Massimo , DI MURO, Vincenzo
发明人： BRAMANTI, Emilia , ZUCCHINI, Fabrizio , ONOR, Massimo , DI MURO, Vincenzo
IPC分类号： G01N21/84 , G01N21/78 , G01N21/76 , G01N21/64 , G01N33/487 , G01N27/327
CPC分类号： G01N27/4168 , G01N21/251 , G01N21/33 , G01N21/6428 , G01N21/76 , G01N21/78 , G01N21/8483 , G01N27/327 , G01N27/3272 , G01N27/3277 , G01N33/48707 , G01N33/52 , Y10T436/201666
摘要： We propose a procedure for the determination of lactic acid or lactate in biological fluids, which is simple and low cost with respect to the known methodologies. This procedure can be used by unskilled personnel and it can be implemented in disposable test strips and portable measure devices. The procedure is based on the photochemical reaction of lactic acid with Fe(III), which is reduced to Fe(II) when irradiated with UV light. The Fe(II), produced proportionally to the amount of lactate in the sample, is determined electrochemically or using its reaction with a colored complexing agent, such as 1,10- phenanthroline, and determined by spectrophotometry. This method is advantageous both for the low cost of the reagents employed, and for their short and long term stability.
摘要翻译：我们提出了一种测定生物体液中乳酸或乳酸盐的方法，相对于已知方法而言，这是简便且成本低的方法。该程序可以由非熟练人员使用，并且可以在一次性测试条和便携式测量装置中实现。该程序基于乳酸与Fe（III）的光化学反应，当用UV光照射时，其被还原成Fe（II）。与样品中乳酸盐成比例地产生的Fe（II）通过电化学方法测定或使用其与有色络合剂如1,10-菲咯啉的反应测定，并通过分光光度法测定。该方法对于所用试剂的低成本以及它们的短期和长期稳定性都是有利的。

52. 发明申请

WO2012140409A1 DEVICE FOR REMOVING DISSOLVED GAS FROM A LIQUID 审中-公开
标题翻译：从液体中除去溶解气体的装置
公开(公告)号：WO2012140409A1
公开(公告)日：2012-10-18
申请号：PCT/GB2012/050747
申请日：2012-04-03
申请人： PALINTEST LIMITED , BIRCH, Stephen , JOHNSTON, Simon
发明人： BIRCH, Stephen , JOHNSTON, Simon
IPC分类号： G01N1/40
CPC分类号： G01N1/4055 , B01D19/001 , G01N1/34 , G01N1/38 , G01N27/4168 , G01N2001/4066
摘要： Device for removing a dissolved gas or volatile component from a liquid sample, to a kit-of-parts comprising the device and an electrochemical sensor for determining the quantity of an analyte (eg chlorite) in the liquid sample and to a method for determining the quantity of the analyte.
摘要翻译：用于从液体样品中除去溶解的气体或挥发性组分的装置，包括该装置的试剂盒和用于确定液体样品中的分析物（例如亚氯酸盐）的量的电化学传感器以及用于确定分析物的数量。

53. 发明申请

WO2012112611A3 AMPEROMETRIC SENSOR SYSTEM 审中-公开
标题翻译：安培计传感器系统
公开(公告)号：WO2012112611A3
公开(公告)日：2012-10-18
申请号：PCT/US2012025125
申请日：2012-02-14
申请人： SILVERI MICHAEL A
发明人： SILVERI MICHAEL A
IPC分类号： G01N17/00 , G01N27/30 , G01N35/08
CPC分类号： G01N27/08 , F04D1/04 , G01N27/06 , G01N27/4168 , Y10T29/49002
摘要： A sensor system that measures at least one parameter of water includes an electronics subsystem and includes a sensor housing electrically and mechanically coupled to the electronics subsystem. The sensor housing encloses a chamber that receives water via at least one inlet and that releases water via at least one outlet. At least one sensor has at least one electrode exposed to water in the chamber. A flow generator causes water to flow through the chamber. A plurality of objects within the chamber move in response to the water flow and abrasively clean the at least one electrode. Preferably, the sensor system includes a chlorine sensor having at least two electrodes. The electronics subsystem applies a first differential voltage between the two electrodes during a measurement interval and then applies a second differential voltage between the two electrodes during an interval following the measurement interval.
摘要翻译：测量水的至少一个参数的传感器系统包括电子子系统，并且包括传感器外壳，所述传感器外壳电气地和机械地耦合到电子子系统。传感器壳体包围经由至少一个入口接收水并通过至少一个出口释放水的腔室。至少一个传感器具有至少一个暴露于室中的水的电极。流量发生器使水流过腔室。腔室内的多个物体响应于水流而移动并磨蚀性地清洁至少一个电极。优选地，传感器系统包括具有至少两个电极的氯传感器。电子子系统在测量间隔期间在两个电极之间施加第一差分电压，然后在测量间隔之后的间隔期间在两个电极之间施加第二差分电压。

54. 发明申请

WO2012010864A1 METHOD AND DEVICE FOR DETERMINING AN OXYDANT IN AN AQUEOUS SOLUTION 审中-公开
标题翻译：用于在水溶液中测定氧化物的方法和装置
公开(公告)号：WO2012010864A1
公开(公告)日：2012-01-26
申请号：PCT/GB2011/051281
申请日：2011-07-08
申请人： PALINTEST LIMITED , BIRCH, Stephen, William , JOHNSTON, Simon, Richard
发明人： BIRCH, Stephen, William , JOHNSTON, Simon, Richard
IPC分类号： G01N27/49 , G01N33/18
CPC分类号： G01N27/4168
摘要： The present invention relates to a method for determining the quantity (eg concentration) of an oxidant of interest such as chlorine dioxide in an aqueous solution and to an electrochemical sensor for determining the quantity of an oxidant of interest in an aqueous solution.
摘要翻译：本发明涉及一种用于确定感兴趣的氧化剂（例如水溶液中的二氧化氯）的量（例如浓度）的方法和用于确定水溶液中感兴趣的氧化剂的量的电化学传感器。

55. 发明申请

WO2011100253A3 CARBON QUANTIFYING APPARATUS AND METHOD 审中-公开
标题翻译：碳量化装置和方法
公开(公告)号：WO2011100253A3
公开(公告)日：2011-12-29
申请号：PCT/US2011024075
申请日：2011-02-08
申请人： HACH CO , RAJASEKHARAN VISHNU
发明人： RAJASEKHARAN VISHNU
IPC分类号： G01N27/06 , G01N27/07 , G01N33/18
CPC分类号： G01N33/1846 , G01N27/02 , G01N27/07 , G01N27/4168
摘要： A carbon quantifying cell (20) configured to receive a fluid is provided, including two or more electrodes (22) positioned at least partially in the fluid, and meter electronics (21) configured to place an electrical oxidization, polarization, and/or adsorption program across the two or more electrodes (22) and at least partially oxidize carbon materials in the fluid, apply an AC voltage of a predetermined amplitude across the two or more electrodes (22), measuring the resulting AC current across the two or more electrodes (22), wherein a ratio of amplitudes and a phase angle difference provides information for calculating a fluid impedance, receive an electrical response of the fluid to the electrical oxidization, polarization, and/or adsorption program, quantify the carbon materials in the fluid using the electrical response, and detect interfering materials in the fluid using the fluid impedance.
摘要翻译：提供了构造成接收流体的碳量化单元（20），包括至少部分地位于流体中的两个或更多个电极（22），以及配置成放置电氧化，极化和/或吸附跨越两个或更多个电极（22）并且至少部分地氧化流体中的碳材料，在两个或更多个电极（22）上施加预定幅度的AC电压，测量跨过两个或更多个电极的所得AC电流（22），其中振幅和相位角差的比提供用于计算流体阻抗的信息，接收流体对电氧化，极化和/或吸附程序的电响应，使用电响应，并使用流体阻抗检测流体中的干扰物质。

56. 发明申请

WO2011103110A1 SIMULTANEOUS DETERMINATION OF CHLORINE AND CHLORATE IN SODIUM HYPOCHLORITE 审中-公开
标题翻译：同时测定氯化钠中的氯离子和氯离子
公开(公告)号：WO2011103110A1
公开(公告)日：2011-08-25
申请号：PCT/US2011/024965
申请日：2011-02-16
申请人： SIEMENS INDUSTRY, INC. , FOSTER, Kevin Anthony
发明人： FOSTER, Kevin Anthony
IPC分类号： C25B1/26
CPC分类号： G01N27/4168
摘要： The present invention relates to systems and processes of wastewater treatment and, in particular, to systems and methods of treating wastewater utilizing biological treatments utilizing two mixed liquor recycle streams for nutrient removal.A process for the simultaneous determination of chlorine and chlorate in sodium hypochlorite. First and second streams of sodium hypochlorite are provided. The first stream is treated to generate iodine indicative of chlorine. The second stream is treated to generate iodine indicative of chlorine and chlorate. The iodine of the first stream is subjected to an amperometric measuring cell to generate a first current proportional to a chlorine concentration of the first stream. The iodine of the second stream is subjected to an amperometric measuring cell to generate a second current proportional to the chlorine and chlorate concentration in the second stream. The first current is subtracted from the second current to determine an amount of chlorate.
摘要翻译：本发明涉及废水处理的系统和方法，特别涉及利用利用两种混合液循环流进行营养物去除的生物处理处理废水的系统和方法。一种同时测定次氯酸钠中氯和氯酸盐的方法。提供第一和第二次次氯酸钠。处理第一流以产生指示氯的碘。处理第二流以产生指示氯和氯酸盐的碘。对第一流的碘进行电流计测量池以产生与第一流的氯浓度成比例的第一电流。对第二流的碘进行电流计测量池以产生与第二流中的氯和氯酸盐浓度成比例的第二电流。从第二电流中减去第一电流以确定氯酸盐的量。

57. 发明申请

WO2008027741A3 ELECTROCHEMICAL CHLORINE SENSOR 审中-公开
标题翻译：电化学氯传感器
公开(公告)号：WO2008027741A3
公开(公告)日：2008-10-30
申请号：PCT/US2007076243
申请日：2007-08-17
申请人： HACH CO , SALZER COREY A
发明人： SALZER COREY A
IPC分类号： G01N27/413
CPC分类号： G01N27/4168
摘要： A sensor (10) for measurement of free chlorine and of total chlorine in aqueous solution including a working electrode (12) having a self-assembled monolayer (SAM) formed on the surface thereof, producing a barrier which reduces the generation of background currents when electrical potentials are applied to the electrode, and blocks the reduction or oxidation of interfering species in the solution, is described. Such SAMs have also been found to block the efficient reduction of chlorine as well. However, N,N-diethyl-p-phenylenediamine (DPD) has been found to effectively transport electrons across the SAM; that is, an oxidized form of DPD produced by a reaction with chlorine is capable of penetrating the SAM such that the reduction of the oxidized DPD species can occur. The generated reduction current is correlated with the concentration of chlorine in solution. Total chlorine may be determined by the addition of an iodide salt.
摘要翻译：一种用于测量水溶液中游离氯和总氯含量的传感器（10），其包括在其表面上形成有自组装单层（SAM）的工作电极（12），产生当减少背景电流产生时的屏障描述了将电位施加到电极并阻断溶液中干扰物种的还原或氧化。此类SAM也被发现阻止氯的有效还原。然而，已发现N，N-二乙基对苯二胺（DPD）有效地将电子穿过SAM传输; 也就是说，通过与氯反应产生的DPD的氧化形式能够穿透SAM，从而可以发生氧化的DPD物质的还原。产生的还原电流与溶液中氯的浓度相关。总氯可以通过加入碘盐来确定。

58. 发明申请

WO2008027741A2 ELECTROCHEMICAL CHLORINE SENSOR 审中-公开
标题翻译：电化学传感器
公开(公告)号：WO2008027741A2
公开(公告)日：2008-03-06
申请号：PCT/US2007/076243
申请日：2007-08-17
申请人： HACH COMPANY , SALZER, Corey A.
发明人： SALZER, Corey A.
IPC分类号： G01N27/26
CPC分类号： G01N27/4168
摘要： A sensor (10) for measurement of free chlorine and of total chlorine in aqueous solution including a working electrode (12) having a self-assembled monolayer (SAM) formed on the surface thereof, producing a barrier which reduces the generation of background currents when electrical potentials are applied to the electrode, and blocks the reduction or oxidation of interfering species in the solution, is described. Such SAMs have also been found to block the efficient reduction of chlorine as well. However, N,N-diethyl-p-phenylenediamine (DPD) has been found to effectively transport electrons across the SAM; that is, an oxidized form of DPD produced by a reaction with chlorine is capable of penetrating the SAM such that the reduction of the oxidized DPD species can occur. The generated reduction current is correlated with the concentration of chlorine in solution. Total chlorine may be determined by the addition of an iodide salt.
摘要翻译：一种传感器（10），用于测量水溶液中的游离氯和总氯，包括在其表面上形成有自组装单层（SAM）的工作电极（12），产生阻挡层，其减少背景电流的产生，描述了将电位施加到电极，并阻止溶液中干扰物质的还原或氧化。也已经发现这样的SAM也阻止氯的有效还原。然而，已经发现N，N-二乙基对苯二胺（DPD）有效地将电子传输穿过SAM; 也就是说，通过与氯反应生成的DPD的氧化形式能够穿透SAM，从而可以发生氧化的DPD物质的还原。产生的还原电流与溶液中氯的浓度相关。总氯可以通过加入碘化物盐来测定。

59. 发明申请

WO2007059455A2 NON-BIOFOULING, UNIVERSAL REDOX ELECTRODE AND MEASUREMENT SYSTEM 审中-公开
标题翻译：非生物化学，通用的氧化还原电极和测量系统
公开(公告)号：WO2007059455A2
公开(公告)日：2007-05-24
申请号：PCT/US2006060821
申请日：2006-11-13
申请人： UNIV VIRGINIA COMMONWEALTH , WARD KEVIN , HAWKRIDGE FRED , BRAHIM SEAN , LEWIS KELVIN L , RHOTEN MELISSA C
发明人： WARD KEVIN , HAWKRIDGE FRED , BRAHIM SEAN , LEWIS KELVIN L , RHOTEN MELISSA C
IPC分类号： C25B5/00
CPC分类号： G01N27/4168
摘要： A universal reduction-oxidation (redox) electrode allows for the temporal measurement of the redox potential of a variety of biological or environmental fluids or tissues, and assists in the diagnosis of matters related to health and disease. The electrode is made from gold which is derivatized with an electron transport promoter, such as 4-pyridinethiol and bis(4-pyridyl)disulfide. The electrode can be used to measure the redox potential of complex mediums without biofouling.
摘要翻译：通用还原 - 氧化（氧化还原）电极可以对各种生物或环境流体或组织的氧化还原电位进行时间测量，并有助于诊断与健康和疾病有关的事项。电极由用电子传递促进剂衍生的金制成，例如4-吡啶硫醇和双（4-吡啶基）二硫化物。电极可用于测量复杂介质的氧化还原电位，而无需生物污染。

60. 发明申请

WO2005022143A2 METHOD AND APPARATUS FOR ASSAY OF ELECTROCHEMICAL PROPERTIES 审中-公开
标题翻译：用于测定电化学性质的方法和设备
公开(公告)号：WO2005022143A2
公开(公告)日：2005-03-10
申请号：PCT/US2004/027441
申请日：2004-08-23
申请人： AGAMATRIX Inc. , IYENGAR, Sridhar G , HARDING, Ian
发明人： IYENGAR, Sridhar G , HARDING, Ian
IPC分类号： G01N33/00
CPC分类号： G01N27/26 , A61B5/14532 , A61B5/1486 , A61B5/1495 , C12Q1/001 , C12Q1/004 , C12Q1/006 , G01N27/3274 , G01N27/4168
摘要： The presence of a select analyte in the sample is evaluated in an an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-detection redox system, thereby forming a chemical potential gradient of the analyte or mediator between the two electrodes After the gradient is established, the applied potential or current is discontinued and an analyte-independent signal is obtained from the relaxation of the chemical potential gradient. The analyte-independent signal is used to correct the analyte-dependent signal obtained during application of the potential or current. This correction allows an improved measurement of analyte concentration because it corrects for device-specific and test specific factors such as transport (mobility) of analyte and/or mediator, effective electrode area, and electrode spacing (and as a result, sample volume), without need for separate calibration values. The analysis can be performed using disposable test strips in a hand held meter, for example for glucose testing.
摘要翻译：使用导电池型设备在电化学系统中评估样品中所选分析物的存在。在电池的两个电极之间产生的电势或电流足以使分析物或分析物在分析物检测氧化还原系统中发生氧化或还原，由此在两个电极之间形成分析物或介体的化学势梯度在建立梯度之后，施加的电势或电流被中止，并且从化学势梯度的松弛中获得与分析物无关的信号。独立于分析物的信号用于校正施加电位或电流期间获得的分析物依赖性信号。这种校正允许改进分析物浓度的测量，因为它校正了分析物和/或介体的传输（迁移率），有效电极面积和电极间距（以及因此样品体积）等器件特异性和测试特定因素，而不需要单独的校准值。分析可以使用手持式仪表中的一次性试纸进行，例如葡萄糖检测。

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