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41. 发明申请

WO2014016687A2 ELECTRICAL TRACES IN AN IMPLANT UNIT 审中-公开
标题翻译：植被单元中的电气轨迹
公开(公告)号：WO2014016687A2
公开(公告)日：2014-01-30
申请号：PCT/IB2013002073
申请日：2013-07-26
申请人： MASHIACH ADI
发明人： MASHIACH ADI
IPC分类号： A61N1/36
CPC分类号： A61B17/0482 , A61N1/0526 , A61N1/0548 , A61N1/0558 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/3606 , A61N1/36071 , A61N1/36075 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36132 , A61N1/36189 , A61N1/37229 , A61N1/375 , A61N1/3787 , H02J7/025 , H02J50/05 , H02J50/12 , H04B5/0031 , H04B5/0037 , H04B5/0081 , H04B5/0093 , Y10T29/49018
摘要： The present disclosure is directed to a device. The device includes a flexible carrier and at least one implantable circuit arranged on the flexible carrier. The device further includes at least one meandering electrical trace disposed on the flexible carrier and arranged to establish an electrically conductive path between a first contact point and a second contact point associated with the at least one implantable circuit. The at least one meandering electrical trace is configured to maintain the electrically conductive path during flexing of the flexible carrier.
摘要翻译：本公开涉及一种设备。该装置包括柔性载体和布置在柔性载体上的至少一个可植入电路。该装置还包括设置在柔性载体上的至少一个曲折电迹线，并布置成在与至少一个可植入电路相关联的第一接触点和第二接触点之间建立导电路径。所述至少一个弯曲电迹线被配置为在柔性载体弯曲期间维持导电路径。

42. 发明申请

WO2013046049A3 DEVICES AND METHODS FOR DELIVERING ENERGY AS A FUNCTION OF CONDITION SEVERITY 审中-公开
标题翻译：将能量作为条件严重程度的功能的装置和方法
公开(公告)号：WO2013046049A3
公开(公告)日：2013-11-07
申请号：PCT/IB2012002443
申请日：2012-09-28
申请人： MASHIACH ADI
发明人： MASHIACH ADI
IPC分类号： A61N1/00
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： A device for regulating energy delivery to an implanted circuit is disclosed. The device may include at least one implantable circuit and at least one pair of implantable electrodes in electrical communication with the circuit. The at least one pair of implantable electrodes may be configured to modulate at least one nerve. The at least one implantable circuit may be configured deliver a signal to the at least one pair of implantable electrodes. The signal may have at least one of a power level or a duration determined based on a severity of a detected physiologic condition.
摘要翻译：公开了一种用于调节到植入电路的能量输送的装置。该装置可以包括至少一个可植入电路和与该电路电连通的至少一对可植入电极。至少一对可植入电极可被配置成调制至少一个神经。所述至少一个可植入电路可以被配置为将信号传递到所述至少一对可植入电极。信号可以具有基于检测到的生理状况的严重性而确定的功率水平或持续时间中的至少一个。

43. 发明申请

WO2013046048A2 DEVICE AND METHOD FOR MODULATING NERVES USING PARALLEL ELECTRIC FIELDS 审中-公开
标题翻译：利用平行电场调节神经的装置和方法
公开(公告)号：WO2013046048A2
公开(公告)日：2013-04-04
申请号：PCT/IB2012002442
申请日：2012-09-28
申请人： MASHIACH ADI
发明人： MASHIACH ADI
IPC分类号： A61N1/05
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： A device may include at least one pair of modulation electrodes configured for implantation in the vicinity of a nerve to be modulated such that the electrodes are spaced apart from one another along a longitudinal direction of the nerve to be modulated. The electrodes may be further configured to facilitate an electric field in response to an applied electric signal, the electric field including field lines extending in the longitudinal direction of the nerve to be modulated. The device may further include at least one circuit in electrical communication with the at least one pair of modulation electrodes and being configured to cause application of the electric signal applied at the at feast one pair of modulation electrodes.
摘要翻译：装置可以包括至少一对调制电极，其被配置用于植入将被调制的神经附近，使得电极沿着待调节的神经的纵向彼此间隔开。电极可以进一步被配置为响应于施加的电信号促进电场，该电场包括在待调节的神经的纵向方向上延伸的场线。该装置可以进一步包括至少一个电路，其与至少一对调制电极电连通，并被配置为引起施加在至少一对调制电极上的电信号的施加。

44. 发明申请

WO2013046035A2 SYSTEMS AND METHODS FOR DETERMINING A SLEEP DISORDER BASED ON POSITIONING OF THE TONGUE 审中-公开
标题翻译：用于确定基于位置的睡眠障碍的系统和方法
公开(公告)号：WO2013046035A2
公开(公告)日：2013-04-04
申请号：PCT/IB2012002364
申请日：2012-09-28
申请人： MASHIACH ADI
发明人： MASHIACH ADI
IPC分类号： A61N1/05
CPC分类号： A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
摘要： Devices and methods are disclosed that include an external unit comprising at least one processor. The processor may be configured to receive a signal indicative of tongue movement in a subject from an implant unit implanted in the subject, determine whether the tongue movement is representative of sleep disordered breathing, generate a modulation control signal to correct the sleep disordered breathing when the at least one processor determines an occurrence of sleep disordered breathing.
摘要翻译：公开了包括包括至少一个处理器的外部单元的装置和方法。处理器可以被配置为从植入在对象中的植入单元接收指示受试者的舌头移动的信号，确定舌头运动是否代表睡眠呼吸紊乱，产生调制控制信号以校正睡眠呼吸紊乱至少一个处理器确定睡眠呼吸紊乱的发生。

45. 发明申请

WO2012139063A3 STIMULATION DEVICES AND METHODS 审中-公开
标题翻译：刺激装置和方法
公开(公告)号：WO2012139063A3
公开(公告)日：2012-12-27
申请号：PCT/US2012032629
申请日：2012-04-06
申请人： OCULEVE INC , UNIV LELAND STANFORD JUNIOR , ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
发明人： ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , KUZMA JANUSZ , PALANKER DANIEL , WETENKAMP SCOTT FRANKLIN
IPC分类号： A61N1/36
CPC分类号： A61N1/37205 , A61N1/0526 , A61N1/36046 , A61N1/37229
摘要： Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a micro stimulator. The components of the controller and micro stimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and micro stimulator may communicate wirelessly or via a wired connection. The micro stimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the micro stimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller.
摘要翻译：这里描述了用于刺激患者中的一种或多种解剖靶的刺激系统和方法，用于诸如干眼症的治疗条件。刺激系统可以包括控制器和微型刺激器。控制器和微型激励器的组件可以在单个单元中或在单独的设备中实现。当单独实现时，控制器和微型激励器可以无线地或经由有线连接进行通信。微型刺激器可以从从控制器接收的信号产生脉冲，并通过一个或多个电极将信号施加到解剖靶上。在一些变型中，微型激励器可以包括被配置为基于从控制器接收的信号产生脉冲的无源发生电路。

46. 发明申请

WO2012140262A1 NEURAL ELECTRODE AND METHOD FOR FABRICATING THE SAME 审中-公开
标题翻译：神经电极及其制作方法
公开(公告)号：WO2012140262A1
公开(公告)日：2012-10-18
申请号：PCT/EP2012/056921
申请日：2012-04-16
申请人： CorTec GmbH , SCHÜTTLER, Martin , DODDS, Christopher W. D. , SUANING, Gregg J.
发明人： SCHÜTTLER, Martin , DODDS, Christopher W. D. , SUANING, Gregg J.
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0526 , A61N1/0551 , Y10T29/49117
摘要： The invention relates to a neural electrode. It relates in particular to such an electrode which is able to withstand high mechanical forces, and to a method of fabrication of the same. The invention discloses an elastic neural electrode, having at least one planar metal layer which comprises conductive material and which is bi-laterally covered by an protective elastomer layer, wherein, for reinforcement of the electrode, an additional reinforcement layer comprising reinforcement material is present between the outermost protective elastomer layers.
摘要翻译：本发明涉及神经电极。特别涉及能够承受高机械力的这种电极及其制造方法。本发明公开了一种弹性神经电极，其具有至少一个平面金属层，其包括导电材料，并且由保护性弹性体层双向覆盖，其中为了加强电极，包括增强材料的附加加强层存在于最外面的保护弹性体层。

47. 发明申请

WO2012082961A3 EXTRACRANIAL IMPLANTABLE DEVICES, SYSTEMS AND METHODS FOR THE TREATMENT OF MEDICAL DISORDERS 审中-公开
标题翻译：用于治疗医疗病症的外部植入式装置，系统和方法
公开(公告)号：WO2012082961A3
公开(公告)日：2012-08-09
申请号：PCT/US2011065003
申请日：2011-12-14
申请人： UNIV CALIFORNIA , NEUROSIGMA INC , US GOV DEPT OF VETERANS AFFAIRS , COOK IAN A , DEGIORGIO CHRISTOPHER M , EKCHIAN LEON , MILLER PATRICK , DESALLES ANTONIO
发明人： COOK IAN A , DEGIORGIO CHRISTOPHER M , EKCHIAN LEON , MILLER PATRICK , DESALLES ANTONIO
IPC分类号： A61N1/04 , A61N1/05 , A61N1/18 , A61N1/36
CPC分类号： A61N1/0551 , A61N1/0504 , A61N1/0526 , A61N1/36053 , A61N1/3606 , A61N1/36064 , A61N1/36085 , A61N1/36089 , A61N1/36096 , A61N1/361 , A61N1/3611 , A61N1/36114 , A61N1/36146 , A61N1/3616 , A61N1/36171 , A61N1/36178
摘要： The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
摘要翻译：本公开涉及用于通过刺激三叉神经的表面元件来治疗医学病症的方法，装置和系统。更具体地说，刺激面部颅外三叉神经的浅支的微创系统，装置和方法，即眶上，滑车上，眶下，颞下，颧骨，颧骨，颧骨，鼻和智力神经（也称为统称为浅表三叉神经）在本文中公开。

48. 发明申请

WO2012073097A2 HELICAL INSERTER 审中-公开
标题翻译：螺旋插入
公开(公告)号：WO2012073097A2
公开(公告)日：2012-06-07
申请号：PCT/IB2011002878
申请日：2011-11-30
申请人： FUEGLISTER FABIAN HERMANN URBAN
发明人： FUEGLISTER FABIAN HERMANN URBAN
IPC分类号： A61N1/05
CPC分类号： A61N1/36078 , A61B17/06066 , A61B17/062 , A61B17/3468 , A61B2017/06052 , A61B2017/06076 , A61N1/0526 , A61N1/0573 , A61N1/3601 , A61N2001/0578
摘要： A method and apparatus for inserting inserts helically into soft tissue is provided. The inserter is made up of a housing assembly, a hollow helical needle; and a matched first and second hypoid gear. In its basic form, the apparatus includes a housing assembly, a hollow helical insert guide, a helical insert drive and a guide removal device. The hollow helical insert guide is held in functional relationship by the housing assembly and is adapted to be loaded with the insert for helical transport therewith into the soft tissue. The helical insert drive drives the helical insert guide in rotation and translation into the soft tissue. When an insert is present within the insert guide, the guide removal device removes the insert guide while leaving the insert in its intended implant location in the soft tissue. The method and apparatus insert an implantable member helically into soft tissue, thereby better fixing the implantable member in the soft tissue when such tissue is deformed.
摘要翻译：提供了一种用于将螺旋插入软组织的方法和装置。插入器由壳体组件，中空螺旋针构成; 以及匹配的第一和第二准双曲面齿轮。在其基本形式中，该装置包括壳体组件，中空螺旋插入件引导件，螺旋插入件驱动器和导向件移除装置。中空的螺旋插入引导件通过壳体组件保持功能关系，并且适于装载插入件，以将其螺旋输送到软组织中。螺旋插入式驱动器驱动螺旋插入件引导件旋转并平移到软组织中。当插入物存在于插入物引导件内时，引导件移除装置移除插入物引导件，同时将插入件留在软组织中的预期植入位置。该方法和装置将可植入构件螺旋地插入软组织中，从而当这种组织变形时将可植入构件更好地固定在软组织中。

49. 发明申请

WO2012054587A2 ELECTRODE ASSEMBLY 审中-公开
标题翻译：电极组件
公开(公告)号：WO2012054587A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056863
申请日：2011-10-19
申请人： RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK , BIKSON, Marom , KRONBERG, Gregory , NAGUIB, Tamer N. , ARCE, Denis , MINHAS, Preet
发明人： BIKSON, Marom , KRONBERG, Gregory , NAGUIB, Tamer N. , ARCE, Denis , MINHAS, Preet
IPC分类号： A61N1/36 , A61N1/04 , A61N1/18
CPC分类号： A61N1/0526 , A61N1/0456 , A61N1/0472 , A61N1/36025
摘要： An electrode assembly includes a substantially porous element configured to be coupled to an electrode for delivery of electrical current to a patient in a neurostimulation procedure. The substantially porous material defining a contact surface, of which at least a portion contacts the patient during the neurostimulation procedure. A first insulating member is coupled to the substantially porous element and exposed at the contact surface to prevent a portion of the contact surface from contacting the patient to deliver the electrical current during the neurostimulation procedure.
摘要翻译：电极组件包括基本上多孔的元件，该基本多孔的元件被配置为与神经刺激过程中的用于向患者输送电流的电极耦合。基本上多孔的材料限定接触表面，在神经刺激过程期间，接触表面的至少一部分接触患者。第一绝缘构件联接到基本多孔元件并且在接触表面处暴露以防止接触表面的一部分接触患者以在神经刺激过程期间递送电流。

50. 发明申请

WO2011151019A1 VORRICHTUNG ZUR TRANSKUTANEN STIMULATION EINES NERVS DES MENSCHLICHEN KÖRPERS 审中-公开
标题翻译：设备技术对人体神经的经皮刺激
公开(公告)号：WO2011151019A1
公开(公告)日：2011-12-08
申请号：PCT/EP2011/002452
申请日：2011-05-18
申请人： CERBOMED GMBH , DIETRICH, Stefan , FISCHENICH, Andrea
发明人： DIETRICH, Stefan , FISCHENICH, Andrea
IPC分类号： A61N1/372 , A61N1/05
CPC分类号： A61N1/36017 , A61N1/0526 , A61N1/0541 , A61N1/08 , A61N1/36114 , A61N1/37247
摘要： Die Erfindung betrifft eine Vorrichtung (1) zur transkutanen Stimulation eines Nervs des menschlichen Körpers, die eine Stimulationsvorrichtung (2) umfasst, die eine Steuerungseinrichtung (3) aufweist, sowie eine mit der Stimulationsvorrichtung (2) in Verbindung stehende Elektrodenanordnung (4) mit mindestens einer Stimulationselektrode (5) und mindestens einer Referenzelektrode (6), wobei die Steuereinrichtung (3) ausgebildet ist, in Abhängigkeit vorgegebener Daten der Elektrodenanordnung (4) einen Stimulationsstrom aufzugeben. Um in einfacher und bedienerfreundlicher Weise die Vorrichtung auf eine gewünschte transkutane Stimulation einstellen zu können, sieht die Erfindung vor, dass die Steuerungseinrichtung (3) mit einem Eingabemittel (7) in Verbindung steht, über das eine Dateneingabe in Form einer Kennung (K) möglich ist, und dass die Steuerungseinrichtung (3) mit einem Datenspeicher (8) in Verbindung steht, wobei der Datenspeicher (8) für eine mindestens zweidimensionale Matrix-Speicherung mindestens zweier den Stimulationsstrom bestimmenden Parameter (f, T) in Abhängigkeit der Kennung (K) ausgebildet ist und wobei die Steuerungseinrichtung (3) zur Vorgabe der mindestens zwei den Stimulationsstrom bestimmenden Parameter (f, T) nach Eingabe der Kennung (K) über die Eingabemittel (7) ausgebildet ist.
摘要翻译：本发明涉及用于人体的神经的经皮刺激的装置（1），包括一刺激装置（2）包括一个控制装置（3），以及具有至少（2）相关电极装置（4）的刺激装置刺激电极（5）和至少一个参比电极（6），其特征在于，形成在依赖控制装置（3）在所述电极组件的预定数据放弃一个刺激电流（4）。为了将设备调整到所希望的经皮刺激以简单且用户友好的方式，本发明提供的是，控制装置（3）中的标识符的形式连接到（7）相关联的输入装置，通过数据输入（K）可能，并且所述控制装置（3）具有在连接的数据存储器（8），其中所述数据存储器（8）中的至少两个的至少二维矩阵存储所确定的刺激电流参数（F，T）作为标识符的函数进行通信（K）形成，并且其中所述控制装置（3），用于经由输入装置（7）的识别（K）的条目之后提供所述至少两个刺激电流确定参数（F，T）形成。

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