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41. 发明申请

WO02065906A3 APPARATUS AND METHOD FOR PERFORMING NERVE CONDUCTION STUDIES WITH LOCALIZATION OF EVOKED RESPONSES 审中-公开
标题翻译：用诱发反应局部化进行神经传导研究的装置和方法
公开(公告)号：WO02065906A3
公开(公告)日：2002-09-26
申请号：PCT/US0204204
申请日：2002-02-14
申请人： NEUROMETRIX INC
发明人： GOZANI SHAI N , MEYER ANN PAVLIK , KONG XUAN , WELLS MARTIN D
IPC分类号： A61B5/0492 , A61B5/11 , A61B5/05
CPC分类号： A61B5/0492 , A61B5/1106 , A61B5/4041 , A61B5/6829 , A61B2562/063 , A61B2562/166
摘要： An apparatus and method for detecting physiological function, for example, nerve conduction, is described. In one embodiment the apparatus includes a housing including a stimulator shaped to fit a first anatomical site and a detector shaped to fit a second anatomical site. The housing automatically positions the detector substantially adjacent to the second anatomical site when the stimulator is positioned substantially adjacent to the first anatomical site. The detector contains a plurality of individual detection elements, whereby the response evoked by stimulation at the first anatomical site is measured using one or more of these detection elements at the second anatomical location.
摘要翻译：描述了用于检测生理功能的设备和方法，例如神经传导。在一个实施例中，该设备包括壳体，该壳体包括成形为适合第一解剖部位的刺激器和成形为适合第二解剖部位的检测器。当刺激器基本上邻近第一解剖部位定位时，外壳自动将检测器定位成与第二解剖部位基本相邻。检测器包含多个单独的检测元件，由此通过在第二解剖位置处的这些检测元件中的一个或多个来测量由第一解剖位置处的刺激引起的响应。

42. 发明申请

WO2002066103A1 A METHOD AND A SYSTEM FOR ADMINISTERING MUSCLE RELAXANT TO A PATIENT 审中-公开
标题翻译：一种用于管理放松对患者的肌肉的方法和系统
公开(公告)号：WO2002066103A1
公开(公告)日：2002-08-29
申请号：PCT/DK2002/000111
申请日：2002-02-19
申请人： AKZO NOBEL N.V. , JANSEN, Willem , DOUGLAS, John, Eleveld , LARSEN, Søren, Anders
发明人： JANSEN, Willem , DOUGLAS, John, Eleveld , LARSEN, Søren, Anders
IPC分类号： A61M5/172
CPC分类号： A61M5/1723 , A61B5/1106 , A61M5/142 , A61M2005/14208 , A61M2005/14292 , A61M2209/02 , G06F19/00 , G06F19/3468
摘要： The invention relates to a system for administering muscle relaxant to a patient. The system includes an infusion pump (102) adapted for delivering said muscle relaxant to a patient, and a controller (101) adapter for controlling the operation of said infusion pump on the basis of at least one received input value. Further the system includes measuring means (103) adapted for continuously measuring the effect of said muscle relaxant on the patient and adapted for supplying a value representing said measured effect as said input value to said controller. According to the invention, on basis of said at least one input value, said controller is adapted for selecting a control value from a set of predetermined control values as the value to be used for controlling said infusion pump. The invention also relates to a method of administering muscle relaxant to a patient and to a testing apparatus adapted to be used for testing the automatic operation of a system for administration of muscle relaxant to a patient.
摘要翻译：本发明涉及一种向患者施用肌肉松弛剂的系统。该系统包括适于将所述肌肉松弛剂递送至患者的输液泵（102），以及用于基于至少一个接收到的输入值来控制所述输液泵的操作的控制器（101）适配器。此外，该系统包括适于连续地测量所述肌肉松弛剂对患者的影响的测量装置（103），并适于将表示所述测量效果的值作为所述输入值提供给所述控制器。根据本发明，基于所述至少一个输入值，所述控制器适于从一组预定控制值中选择一个控制值作为用于控制所述输液泵的值。本发明还涉及向患者施用肌肉松弛剂的方法以及适用于测试用于向患者施用肌肉松弛剂的系统的自动操作的测试装置的方法。

43. 发明申请

WO02003861A1 MONITORING OF PATIENT'S ELECTRICAL CHARACTERISTICS 审中-公开
标题翻译：监测患者的电气特征
公开(公告)号：WO02003861A1
公开(公告)日：2002-01-17
申请号：PCT/FI2001/000666
申请日：2001-07-12
IPC分类号： A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/053 , A61B5/11 , A61B5/04
CPC分类号： A61B5/0488 , A61B5/0402 , A61B5/0476 , A61B5/0535 , A61B5/1106
摘要： The invention relates to a method and a system for a medical monitoring system, in which method the functions of a patient are measured, and the change in the electric activity of the patient are observed. In the method, the electrocardiogram (EKG), electroencephalogram (EEG), and impedance cardiograph signal (IKG) are being measured with one piece of measuring equipment.
摘要翻译：本发明涉及一种医疗监视系统的方法和系统，其中测量患者的功能，观察患者的电活动变化。在该方法中，使用一块测量设备测量心电图（EKG），脑电图（EEG）和阻抗心电图信号（IKG）。

44. 发明申请

WO01093748A2 RELATIVE NERVE MOVEMENT AND STATUS DETECTION SYSTEM AND METHOD 审中-公开
标题翻译：相对神经运动和状态检测系统及方法
公开(公告)号：WO01093748A2
公开(公告)日：2001-12-13
申请号：PCT/US2001/018579
申请日：2001-06-08
IPC分类号： A61B5/0488 , A61B5/05 , A61B5/11 , A61N1/08 , A61B
CPC分类号： A61B5/4893 , A61B5/0488 , A61B5/05 , A61B5/1106 , A61B5/4041 , A61N1/08
摘要： A method and system for detecting nerve status and relative movement between a nerve and a proximity electrode. The method determines relative movement between a nerve and a proximity electrode by applying multiple signals to a calibration electrode where the energy level of each signal induces a predetermined nerve response. The method also applies multiple signals to the proximity electrode where the energy level of each signal also induces a predetermined nerve response. Based on the variation of the energy level of signals required to induce predetermined nerve responses, the method may detect relative movement between a nerve and a proximity electrode and nerve status.
摘要翻译：用于检测神经状态和神经与接近电极之间的相对运动的方法和系统。该方法通过将多个信号施加到校准电极来确定神经和接近电极之间的相对运动，其中每个信号的能级引起预定的神经反应。该方法还将多个信号施加到接近电极，其中每个信号的能量水平也诱导预定的神经反应。基于诱导预定神经反应所需的信号的能量水平的变化，该方法可以检测神经和接近电极之间的相对运动以及神经状态。

45. 发明申请

WO99019020A1 MAGNETICALLY COMPATIBLE PERIPHERAL NERVE STIMULATOR 审中-公开
标题翻译：磁性兼容外周神经刺激器
公开(公告)号：WO99019020A1
公开(公告)日：1999-04-22
申请号：PCT/US1998/021834
申请日：1998-10-15
IPC分类号： A61B5/055 , A61B5/11 , A61N1/36
CPC分类号： A61N1/025 , A61B5/055 , A61B5/1106 , A61N1/36014 , A61N1/3718 , A61N1/3756 , A61N1/378
摘要： The present invention provides a peripheral nerve stimulator (10) of low magnetic susceptibility that can be used in the high magnetic field of an MRI suite. Non-magnetic lithium batteries power the peripheral nerve stimulator. A stack of capacitors, and diodes (hereinafter "components") forming a voltage multiplier (20) replace the conventional step-up transformer. Each component is carefully chosen for low content of the magnetic materials. To minimise the number of components, and enable the magnetically compatible peripheral nerve stimulator to be a handheld instrument, a full H bridge supplies power to the multiplier. The power is an AC signal with voltage equal or plus or minus to the supply voltage. This provides a peak to peak voltage value of two times the available battery voltage. This approach reduces the number of capacitors, and diodes to half compared to the half bridge solution.
摘要翻译：本发明提供了可用于MRI套件的高磁场的低磁化率的周围神经刺激器（10）。非磁性锂电池为周围神经刺激器供电。形成电压倍增器（20）的一叠电容器和二极管（以下称为“部件”）代替传统的升压变压器。仔细选择每个组件用于低含量的磁性材料。为了最小化组件的数量，并使磁兼容的外围神经刺激器成为手持式仪器，全H桥向乘法器供电。电源是电压等于或正负电源电压的交流信号。这提供了可用电池电压的两倍的峰峰值电压值。与半桥解决方案相比，这种方法将电容器和二极管的数量减少了一半。

46. 发明申请

WO1998010701A1 ANAESTHESIA CONTROL SYSTEM 审中-公开
标题翻译：麻醉控制系统
公开(公告)号：WO1998010701A1
公开(公告)日：1998-03-19
申请号：PCT/GB1997002435
申请日：1997-09-10
申请人： THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW , MANTZARIDIS, Haralambos , KENNY, Gavin, Nicholson, Cleghorn
发明人： THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
IPC分类号： A61B05/11
CPC分类号： A61B5/4821 , A61B5/1106 , A61B5/6814 , A61B5/7239 , A61B2505/05
摘要： An anaesthesia control system and a method of calculating an index representative of the depth of anaesthesia is disclosed. The method comprises subjecting a patient to a repetitive audio stimulus and monitoring auditory evoked potentials (AEP) produced by the patient and then recording these auditory evoked potentials using EEG recording means and providing a signal corresponding to the coarseness of the monitored AEP signal and using this signal as an index indicative of anaesthetic depth. The raw AEP signal is divided into a series of sweeps and each sweep is synchronised with the repetitive audio stimulus and sweeps are recorded in sequence to produce a time averaged sweep from which the anaesthetic index is calculated. The anaesthetic index is constantly updated by repeatedly conducting a successive series of sweeps. The system and index signal can be used as part of an anaesthesia control system for regulating the supply of anaesthetic to the patient to maintain the anaesthetic index at a predetermined level.
摘要翻译：公开了一种麻醉控制系统和计算代表麻醉深度的指标的方法。该方法包括使患者接受由患者产生的重复音频刺激和监测听觉诱发电位（AEP），然后使用EEG记录装置记录这些听觉诱发电位，并提供对应于所监测的AEP信号的粗糙度的信号并使用该信号信号作为指示麻醉深度的指标。原始AEP信号被分成一系列扫描，并且每个扫描与重复的音频刺激同步，并且依次记录扫描以产生计算麻醉指数的时间平均扫描。麻醉指数不断更新，重复进行连续的扫描。系统和指标信号可以用作麻醉控制系统的一部分，用于调节向患者供应麻醉剂以将麻醉指数维持在预定水平。

47. 发明申请

WO1996006569A2 PHYSIOLOGIC TOURNIQUET 审中-公开
标题翻译：生理餐具
公开(公告)号：WO1996006569A2
公开(公告)日：1996-03-07
申请号：PCT/IB1995000927
申请日：1995-08-25
申请人： ABATIS MEDICAL TECHNOLOGIES LTD. , McEWEN, James, A. , JAMESON, Michael
发明人： ABATIS MEDICAL TECHNOLOGIES LTD.
IPC分类号： A61B17/12
CPC分类号： A61B5/1106 , A61B5/6828 , A61B5/6829 , A61B5/7435 , A61B17/1355 , A61B2505/05 , A61B2560/02
摘要： A configuration register is incorporated into an electrically powered tourniquet apparatus for enabling an operator to change the values of parameters initially employed at the time of the next use of the apparatus, such as the initial pressure settings and elapsed time limits. These changed initial values of parameters are stored in memory and remain there despite inadvertent or intentional interruption of electrical power to the apparatus. An event register provides capability for recording the occurrence of events (cuff inflation, cuff deflation, etc.) and for relating the occurrence of the events to hazards and undesirable outcomes such as nerve damage associated with tourniquet usage. A safety circuit is included to detect and respond safely to certain failures which are possible within the tourniquet apparatus.
摘要翻译：配置寄存器被结合到电动止血带装置中，以使得操作者能够改变在下一次使用装置时最初采用的参数的值，诸如初始压力设置和经过的时间限制。这些改变的参数初始值被存储在存储器中，并且保持在这里，尽管无意或有意地中断了设备的电力。事件记录提供了记录事件发生（袖带通气，袖带通气等）的能力，并且将事件的发生与危害和不期望的结果相关联，例如与止血带使用相关的神经损伤。包括一个安全电路，以便对止血带设备中可能的某些故障进行安全检测和响应。

48. 发明申请

WO1992019172A1 APPARATUS PARTICULARLY FOR USE IN THE DETERMINATION OF THE CONDITION OF THE VEGETATIVE PART OF THE NERVOUS SYSTEM 审中-公开
标题翻译：特别用于确定神经系统植物部分条件的装置
公开(公告)号：WO1992019172A1
公开(公告)日：1992-11-12
申请号：PCT/NL1992000079
申请日：1992-04-29
申请人： LERNER, Eduard, Naumovich
IPC分类号： A61B90/00
CPC分类号： A61B5/0533 , A61B5/1106 , A61B5/4011 , A61B5/4035
摘要： Apparatus for use in the determination of the condition of the vegetative part of the nervous system and/or of sensory functions of an organism, i.e. a human being or animal. The apparatus comprises means (1-8) for generating and supplying to said organism at least one sensory stimulus chosen from a group of sensory stimuli, such as visual, sound, olfactory, gustatory, tactile or pain stimuli, and means (9, 19) for measuring the skin potential and the evoked response of the organism to a stimulus. The measured data are processed by processing means (14) for automatically controlling the supply of said at least one stimulus for providing a non-rythmical sequence of stimuli. Preferably pairs of stimuli are supplied for developing a conditioned reflex.
摘要翻译：用于确定神经系统的营养部分的状况和/或生物（即人或动物）的感官功能的装置。该装置包括用于向所述生物体产生和供应至少一种感觉刺激的装置（1-8），所述感觉刺激选自一组感觉刺激，例如视觉，声音，嗅觉，味觉，触觉或疼痛刺激，以及手段（9,19 ）用于测量生物体对刺激物的皮肤电位和诱发反应。所述测量数据由处理装置（14）处理，用于自动控制所述至少一个刺激的供给，以提供非节奏的刺激序列。优选地，提供成对的刺激以产生条件反射。

49. 发明申请

WO2017221037A1 METHOD AND GLOVE/DEVICE FOR THE DETERMINATION AND IMPROVED EVALUATION OF THE MOTOR SYMPTOMS OF A DISEASE 审中-公开
标题翻译：方法和手套/装置用于确定和改进评估疾病的电机症状
公开(公告)号：WO2017221037A1
公开(公告)日：2017-12-28
申请号：PCT/GR2017/000034
申请日：2017-06-21
申请人： TZALLAS, Alexandros , TSIPOURAS, Markos , SMANIS, Ioannis , KATERTSIDIS, Nikolaos , GIANNAKEAS, Nikolaos
发明人： TZALLAS, Alexandros , TSIPOURAS, Markos , SMANIS, Ioannis , KATERTSIDIS, Nikolaos , GIANNAKEAS, Nikolaos
IPC分类号： A61B5/04 , A61B5/11 , A61B5/00
CPC分类号： A61B5/1101 , A61B5/04 , A61B5/1106 , A61B5/1125 , A61B5/4082 , A61B5/4839 , A61B5/4842 , A61B5/6806 , A61B5/6825 , A61B5/6826 , A61B2560/0475 , A61B2562/0219
摘要： This invention concerns a device/glove (1) which constitutes a precise measuring instrument of an individual's motor status, as well as the device's technical equipment and support method during the measurement and processing of results for determining motor status. According to this invention, the glove/device (1) offers innovative potential for monitoring and offering individualized treatment to patients, as well as for conducting extensive group studies. According to this invention, the glove/device (1) is particularly suitable for supporting patients suffering from Parkinson's disease.
摘要翻译：本发明涉及一种构成个人电机状态的精确测量仪器的装置/手套（1），以及在测量和处理用于确定电机的结果期间的装置的技术设备和支持方法状态。根据本发明，手套/装置（1）提供了用于监测和向患者提供个体化治疗以及进行广泛的小组研究的创新潜力。根据本发明，手套/装置（1）特别适用于支撑患有帕金森病的患者。

50. 发明申请

WO2015097174A2 MONITORING A NEUROMUSCULAR BLOCKADE STATUS 审中-公开
标题翻译：监测神经阻滞状态
公开(公告)号：WO2015097174A2
公开(公告)日：2015-07-02
申请号：PCT/EP2014079041
申请日：2014-12-22
申请人： RODIERA OLIVÉ JOSÉ JAVIER , RGB MEDICAL DEVICES S A , FUNDACIÓ EURECAT
发明人： RODIERA OLIVÉ JOSÉ JAVIER , GONZÁLEZ MARTÍNEZ ANTONIO , CORRAL HERRANZ FRANCISCO JAVIER , RUIZ NOLASCO RICARDO , CARENAS ESPINOLA CARLOS , DE HARO MARMOLEJO CARMEN , RODRÍGUEZ GUTIÉRREZ ROSA , CAMÍ CASALS ANTONI , CALZADILLA GISBERT FRANCISCO JAVIER , LACHARMOISE PAUL DOMINIQUE , COT CANTÓ MARTA
IPC分类号： A61N1/04
CPC分类号： A61B5/1106 , A61B5/02233 , A61B5/0488 , A61B5/05 , A61B5/1107 , A61B5/4519 , A61B5/4836 , A61B5/4848 , A61B5/6824 , A61B5/6828 , A61B5/6831 , A61B5/7203 , A61B5/7275 , A61B2505/05 , A61B2562/0219 , A61B2562/0247 , A61N1/0452 , A61N1/0484 , A61N1/0492 , A61N1/0496 , A61N1/0556 , A61N1/0558 , A61N1/36003
摘要： The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro¬ stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.
摘要翻译：本公开涉及用于确定神经肌肉阻滞状态的各种方法和适于执行这些方法的系统。本公开还涉及用于刺激患者肌肉的电刺激电极，任选地在至少一些所述方法的上下文中。本公开还涉及用于电刺激袖带中的混合空气信号连接器，其可以在至少一些所引用的方法的上下文中使用。本公开还涉及电刺激电路，其包括电极部分和适于用于电刺激的压力袖带的轨道部分，以及构造成围绕患者肢体布置的压力袖带，并且包括活性电刺激电极和无源电刺激电极。这些电刺激电路和压力袖口也可以在至少一些所提及的方法的上下文中使用。

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