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41. 发明申请

WO2008073711A2 ORDERED POLYMER SYSTEM AND INTRAOCULAR LENS 审中-公开
标题翻译：有序聚合物系统和眼内透镜
公开(公告)号：WO2008073711A2
公开(公告)日：2008-06-19
申请号：PCT/US2007/085851
申请日：2007-11-29
申请人： BAUSCH & LOMB INCORPORATED , SALAMONE, Joseph, C.
发明人： SALAMONE, Joseph, C.
CPC分类号： A61L27/16 , A61L2430/16 , C08L33/24
摘要： An intraocular lens with an ordered polymer system contained within a lens capsule or a membrane in the lens capsule. The ordered polymer system includes at least one negatively charged copolymer comprising hydrophilic groups, anionic groups and hydrophobic groups, and at least one positively charged copolymer comprising hydrophilic groups, cationic groups and hydrophobic groups. The at least one negatively charged copolymer and the at least one positively charged copolymer are associatively arranged through non-covalent interactions in the lens capsule or the membrane.
摘要翻译：具有包含在晶状体囊或晶状体囊中的膜内的有序聚合物系统的人工晶状体。有序聚合物体系包括至少一种含有亲水基团，阴离子基团和疏水基团的带负电荷的共聚物，以及至少一种带有亲水基团，阳离子基团和疏水基团的带正电荷的共聚物。该至少一种带负电荷的共聚物和至少一种带正电荷的共聚物通过晶状体胶囊或膜中的非共价相互作用进行缔合排列。

42. 发明申请

WO2007146683A2 OPHTHALMIC COMPOSITIONS COMPRISING A BRANCHED, GLYCEROL MONOALKYL COMPOUND AND A FATTY ACID MONOESTER 审中-公开
标题翻译：包含分支的，甘油单甲醛化合物和脂肪酸单体的组合物
公开(公告)号：WO2007146683A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/070461
申请日：2007-06-06
申请人： BAUSCH & LOMB INCORPORATED , BURKE, Susan, E. , PHILLIPS, Eric , ZHAO, Fang , BARNIAK, Vicki, L. , SALAMONE, Joseph, C.
发明人： BURKE, Susan, E. , PHILLIPS, Eric , ZHAO, Fang , BARNIAK, Vicki, L. , SALAMONE, Joseph, C.
IPC分类号： A61K9/08 , A61L12/14
CPC分类号： A61K9/0048 , A61L12/141 , A61L12/142 , A61L12/143 , A61L12/145 , C11D1/667 , C11D3/0026 , C11D3/0078 , C11D3/2068 , C11D3/2093 , C11D3/30 , C11D3/3427 , C11D3/48 , Y10S134/901
摘要： An aqueous ophthalmic composition comprising a branched, glycerol monoalkyl compound and a fatty acid monoester. The fatty acid monoester comprises an aliphatic fatty acid portion having six to fourteen carbon atoms and an aliphatic hydroxyl portion. The composition will also have an osmolality in a range from 200 mOsmol/kg to 400 mOsmol/kg. The invention is also directed to a method of inhibiting the formation of foam in an aqueous ophthalmic composition that includes a surfactant as well as to a method of enhancing the biocidal efficacy of an aqueous ophthalmic composition containing a fatty acid monoester.
摘要翻译：一种含有支链甘油单烷基化合物和脂肪酸单酯的眼用组合物。脂肪酸单酯包含具有6至14个碳原子的脂族脂肪酸部分和脂族羟基部分。组合物还将具有在200mOsmol / kg至400mOsmol / kg范围内的重量摩尔渗透压浓度。本发明还涉及在包含表面活性剂的水性眼用组合物中抑制泡沫形成的方法以及提高含有脂肪酸单酯的水性眼用组合物的杀生物功效的方法。

43. 发明申请

WO2007098440A1 STAR MACROMONOMERS AND POLYMERIC MATERIALS AND MEDICAL DEVICES COMPRISING SAME 审中-公开
标题翻译： STAR MACROMONOMERS和聚合物材料和包含其的医疗装置
公开(公告)号：WO2007098440A1
公开(公告)日：2007-08-30
申请号：PCT/US2007/062419
申请日：2007-02-20
申请人： BAUSCH & LOMB INCORPORATED , SALAMONE, Joseph, C. , KUNZLER, Jay, F.
发明人： SALAMONE, Joseph, C. , KUNZLER, Jay, F.
IPC分类号： C08G83/00 , C08F287/00 , C08F293/00 , G02B1/04 , C08G77/42
CPC分类号： C08F8/42 , G02B1/043 , C08L53/00 , C08L87/00
摘要： A star macromonomer comprises multiple side chains attached to a nucleus, each side chain having at least a segment comprising hydrophobic units and at least a segment comprising hydrophilic units. Polymeric materials having improved oxygen permeability and water and ion transport rates are produced by polymerizing compositions comprising such a star macromonomer. Such polymeric materials are desirable for producing medical devices, such as ophthalmic devices.
摘要翻译：星形大分子单体包含连接到核的多个侧链，每个侧链具有至少一个包含疏水单元的区段和至少一个包含亲水单元的区段。具有改善的氧气渗透性和水和离子传输速率的聚合材料是通过聚合包含这种星形大分子单体的组合物制备的。这种聚合物材料对于生产医疗装置如眼科装置是理想的。

44. 发明申请

WO2007082113A2 SILOXANE PREPOLYMER CONTAINING PENDANT CATIONIC AND POLYMERIZABLE GROUPS 审中-公开
标题翻译：含有阳离子和聚合物组合物的硅氧烷预聚物
公开(公告)号：WO2007082113A2
公开(公告)日：2007-07-19
申请号：PCT/US2007/060029
申请日：2007-01-03
申请人： BAUSCH & LOMB INCORPORATED , SCHORZMAN, Derek, A. , SALAMONE, Joseph, C. , KUNZLER, Jay, F.
发明人： SCHORZMAN, Derek, A. , SALAMONE, Joseph, C. , KUNZLER, Jay, F.
CPC分类号： C08G77/388 , G02B1/043
摘要： An antenna configuration for a flip type mobile phone 100 is disclosed. The antenna configuration is designed to reduce, to a hearing aid compatibility (HAC) M3 rating or better, any scattered EM field effects that can cause interference to an active hearing aid. The antenna configuration comprises a halfwave type antenna 140 extendable from the lower portion of the mobile phone 100. The antenna 140 does not share the same vertical axis as the lower portion of the mobile phone 100 when extended. Rather, it forms a tilt angle (α) that extends the antenna 140 away from the upper portion of the mobile phone creating a greater separation distance between the speaker 110 and the antenna 140. An antenna feed contact 150 couples the antenna 140 to components within the mobile phone 100. An antenna matching network 400 can tune and attenuate the antenna configuration to enhance operation in the GSM frequency bands.
摘要翻译：公开了一种用于翻盖式移动电话100的天线配置。天线配置旨在降低助听器兼容性（HAC）M3等级或更好的任何散射的EM场效应，从而对主动助听器造成干扰。天线配置包括可从移动电话100的下部延伸的半波型天线140.当延伸时，天线140不与手机100的下部共享相同的垂直轴。相反，它形成了将天线140延伸远离移动电话的上部的倾斜角（a），从而在扬声器110和天线140之间产生更大的间隔距离。天线馈送触点150将天线140耦合到天线匹配网络400可以调谐和衰减天线配置以增强GSM频带中的操作。

45. 发明申请

WO2007005348A1 POLYMERIZATION PRODUCTS AND BIOMEDICAL DEVICES CONTAINING SAME 审中-公开
标题翻译：聚合产物和含有其的生物医学装置
公开(公告)号：WO2007005348A1
公开(公告)日：2007-01-11
申请号：PCT/US2006/024679
申请日：2006-06-23
申请人： BAUSCH & LOMB INCORPORATED , SCHORZMAN, Derek , SALAMONE, Joseph, C.
发明人： SCHORZMAN, Derek , SALAMONE, Joseph, C.
IPC分类号： G02B1/04 , C08F214/18 , C08F236/00 , C08F290/06
CPC分类号： C08G77/385 , C08F214/18 , C08F290/062 , C08F290/068 , G02B1/043 , C08L27/12
摘要： Polymerization products formed from a monomeric mixture comprising (a) one or more first monomers of the general formula I: (I) wherein R 1 represents one or more inertly substituted groups; X is independently a group which links the inertly substituted groups and the trifluorovinyl group; L is an optional linking group; A is CO 2 Z, SO 2 Z, PO 3 Z, or OPO 3 Z wherein Z is hydrogen or an alkali metal and n is an integer of 1 to about 1000; (b) one or more second crosslinking monomers comprising at least three trifluorovinyl groups and (c) one or more prepolymers comprising one or more trifluorovinyl groups are provided. Also provided are biomedical devices formed from such polymerization products.
摘要翻译：由单体混合物形成的聚合产物包含（a）一种或多种通式I的（I）的第一单体，其中R 1表示一个或多个惰性取代的基团; X独立地是连接惰性取代基和三氟乙烯基的基团; L是可选的连接基团; A是CO 2 Z，SO 2 Z，PO 3 Z或OPO 3 Z，其中Z是氢或碱金属，n为1〜1000的整数，（b）提供包含至少三个三氟乙烯基的一种或多种第二交联单体和（c）一种或多种包含一个或多个三氟乙烯基的预聚物。还提供了由这种聚合产物形成的生物医学装置。

46. 发明申请

WO2007005334A1 PERFLUOROCYCLOBUTANE COPOLYMERS 审中-公开
标题翻译：全氟聚醚共聚物
公开(公告)号：WO2007005334A1
公开(公告)日：2007-01-11
申请号：PCT/US2006/024543
申请日：2006-06-23
申请人： BAUSCH & LOMB INCORPORATED , SCHORZMAN, Derek , SALAMONE, Joseph, C.
发明人： SCHORZMAN, Derek , SALAMONE, Joseph, C.
IPC分类号： C08G65/00
CPC分类号： C08G65/337 , C08G61/12 , G02B1/043
摘要： The present invention provides copolymer having repeating units based on polyoxyalkylene radicals, polysiloxane radicals and perfluorocyclobutane radicals. The copolymers are useful as biomedical devices such as contact lenses or intraocular lenses.
摘要翻译：本发明提供了基于聚氧化烯基，聚硅氧烷基和全氟环丁烷基的重复单元的共聚物。该共聚物可用作生物医学装置如隐形眼镜或人工晶状体。

47. 发明申请

WO2007002231A1 FEMTOSECOND LASER MICROMACHINING OF A CONTACT LENS AND A CONTACT LENS MANUFACTURED THEREBY 审中-公开
标题翻译：接触透镜的FEMTOSECOND激光微机械及其制造的接触镜头
公开(公告)号：WO2007002231A1
公开(公告)日：2007-01-04
申请号：PCT/US2006/024201
申请日：2006-06-21
申请人： BAUSCH & LOMB INCORPORATED , ERICKSON, Paul, M. , KUNZLER, Jay, F. , SALAMONE, Joseph, C.
发明人： ERICKSON, Paul, M. , KUNZLER, Jay, F. , SALAMONE, Joseph, C.
IPC分类号： B23K26/36 , G02C7/04 , B23K26/38 , B29D11/00
CPC分类号： B23K26/0624 , B23K26/364 , B23K26/389
摘要： A method of providing a feature on a contact lens including applying a femtosecond laser beam to ablate at least a portion of the contact lens to provide the feature on the contact lens. In one embodiment, the femtosecond laser beam has a pulse width between 10x10 -15 seconds and 200x10 -15 seconds, and has a wavelength between 100 nm and 1500 nm. A contact lens is also provided including at least one fenestration fluidically connecting the anterior surface and the posterior surface, the fenestration being formed using a femtosecond laser in a manner that areas surrounding the fenestration are substantially free of heat damage.
摘要翻译：一种在隐形眼镜上提供特征的方法，包括施加飞秒激光束以消融隐形眼镜的至少一部分以在隐形眼镜上提供特征。在一个实施例中，飞秒激光束的脉冲宽度在10×10 -15秒至200×10 -15秒之间，波长在100nm与1500nm之间。还提供隐形眼镜，其包括至少一个使前表面和后表面流体连接的开窗，所述开窗采用飞秒激光以围绕开窗区域基本上没有热损伤的方式形成。

48. 发明申请

WO2006138193A1 HIGH REFRACTIVE-INDEX, HYDROPHILIC, ARYLSILOXY-CONTAINING MACROMONOMERS AND POLYMERS, AND OPHTHALMIC DEVICES COMPRISING SUCH POLYMERS 审中-公开
标题翻译：高折射率，含羟基的含有硅氧烷的大分子单体和聚合物，以及包含这种聚合物的光学装置
公开(公告)号：WO2006138193A1
公开(公告)日：2006-12-28
申请号：PCT/US2006/022699
申请日：2006-06-12
申请人： BAUSCH & LOMB INCORPORATED , SALAMONE, Joseph, C. , KUNZLER, Jay, F. , OZARK, Richard, M.
发明人： SALAMONE, Joseph, C. , KUNZLER, Jay, F. , OZARK, Richard, M.
IPC分类号： C08G77/20 , G02B1/04
CPC分类号： C08G77/38 , C08G77/20 , G02B1/043 , Y10S525/937 , C08L83/04
摘要： Hydrophilic, arylsiloxy-containing macromonomers have at least a terminal hydrophilic group attached to an arylsiloxy group. The aryl groups attached to siloxy groups can be substituted with other hydrophilic groups. Polymers comprising such hydrophilic, arylsiloxy-containing macromonomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
摘要翻译：亲水性，含芳基甲硅烷氧基的大分子单体具有至少一个与芳基甲硅烷氧基连接的亲水基团。连接到甲硅烷氧基的芳基可以被其它亲水基取代。包含这种亲水的含芳基甲硅烷氧基的大分子单体的聚合物避免或降低形成吸收水的空泡的风险。此外，这种聚合物具有高折射率，因此有利地用于制造眼科装置，例如眼内透镜，隐形眼镜，角膜环，角膜嵌体和角膜假体。

49. 发明申请

WO2006026170A1 COMPOSITIONS CONTAINING N,N,N',N'-TETRAKIS(HYDROXYALKYL)DIAMINE- OR N,N,N',N'-TETRAKIS(HYDROXYALKOXY) DIAMINE-BASED BUFFERS 审中-公开
标题翻译：含有N，N，N'，N'-四（羟基甲基）二胺或N，N，N'，N'-四（羟基烷氧基）二胺基缓冲剂的组合物
公开(公告)号：WO2006026170A1
公开(公告)日：2006-03-09
申请号：PCT/US2005/029267
申请日：2005-08-17
申请人： BAUSCH & LOMB INCORPORATED , SALAMONE, Joseph, C. , BORAZJANI, Roya, Nicole , AMMON, Daniel, M., Jr.
发明人： SALAMONE, Joseph, C. , BORAZJANI, Roya, Nicole , AMMON, Daniel, M., Jr.
IPC分类号： A61L12/14
CPC分类号： C11D7/3218 , A01N33/08 , A61L12/141 , A61L12/142 , A61L12/143 , A61L12/145 , C11D3/0078 , A01N47/44 , A01N33/12 , A01N2300/00
摘要： The use of compositions containing one or more antimicrobial agents with one or more (hydroxyalkyl)diamine-based buffers, (hydroxyalkoxy)diamine-based buffers or combinations thereof to disinfect and/or preserve medical devices is described. Solutions containing one or more antimicrobial agents with one or more (hydroxyalkyl)diamine-based buffers, (hydroxyalkoxy)diamine-based buffers or combinations thereof and methods of making and using the same are also described.
摘要翻译：描述了含有一种或多种抗微生物剂与一种或多种（羟烷基）二胺基缓冲剂，（羟基烷氧基）二胺类缓冲剂或其组合物的组合物对消毒和/或保存医疗器械的用途。还描述了含有一种或多种抗微生物剂与一种或多种（羟基烷基）二胺基缓冲剂，（羟基烷氧基）二胺基缓冲剂或其组合的溶液以及制备和使用它们的方法。

50. 发明申请

WO2006012155A1 XANTHAN GUM VISCOELASTIC COMPOSITION FOR VISCOSURGERY 审中-公开
标题翻译： XANTHAN胶粘剂粘胶组合物
公开(公告)号：WO2006012155A1
公开(公告)日：2006-02-02
申请号：PCT/US2005/022122
申请日：2005-06-22
申请人： BAUSCH & LOMB INCORPORATED , SALAMONE, Joseph, C. , JANI, Dharmendra, M.
发明人： SALAMONE, Joseph, C. , JANI, Dharmendra, M.
IPC分类号： A61K31/723
CPC分类号： A61K31/723 , A61K9/0048 , A61L27/34 , A61L31/042 , A61L31/145 , C08L5/00
摘要： The present invention is a novel viscoelastic composition that includes a suitable aqueous carrier and xanthan gum. The novel viscoelastic composition has rheological properties consistent with a good dispersive viscoelastic and improved damping ability over commercial dispersive viscoelastics.
摘要翻译：本发明是一种新型粘弹性组合物，其包含合适的水性载体和黄原胶。新型粘弹性组合物具有与商业色散粘弹性良好的分散粘弹性和改进的阻尼能力一致的流变特性。

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