专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2019236952A1 POROUS COMPOSITIONS AND RELATED METHODS 审中-公开
公开(公告)号：WO2019236952A1
公开(公告)日：2019-12-12
申请号：PCT/US2019/035968
申请日：2019-06-07
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人： SWAGER, Timothy, M. , HE, Yuan , SMITH, Zachary , LIN, Sharon , BENEDETTI, Francesco, Maria
IPC分类号： B01J20/26 , C07C67/293 , C07C69/604 , C08J3/24 , C08L65/00 , C09K19/32
摘要： Porous compositions such as flexible polymers with side chain porosity are generally provided. In some embodiments, the composition comprises a flexible polymer backbone and a plurality of rigid side chains. In some embodiments, the rigid side chains form pores. In some embodiments, the rigid side chains may comprise two or more [2.2.2] bicyclic cores (e.g., formed by a ring opening metathesis polymerization. The compounds and methods described herein may be useful in various applications including, for example, gas separation.

32. 发明申请

WO2019229592A1 PROCESS FOR PRODUCTION OF DIOL ESTERS FROM ESTERS OF MONO ALCOHOLS 审中-公开
公开(公告)号：WO2019229592A1
公开(公告)日：2019-12-05
申请号：PCT/IB2019/054239
申请日：2019-05-22
申请人： SABIC GLOBAL TECHNOLOGIES B.V.
发明人： DHOKE, Chaitanya , NAIR, Sreejit , DESHPANDE, Raj , NANJUNDAGOUNDER CHINNADORAI, Karthik , AKURI, Satyanarayana
IPC分类号： C07C67/293 , C07C69/08
摘要： Systems and methods of producing diol esters via coupling reactions are disclosed. A monohydric alcohol ester is used as the reactant in a coupling reaction to form a diol ester with or without the presence of a catalyst. Furthermore, the coupling reaction can be performed with or without mixing oxygen with the reactant. This method provides an additional or alternative pathway to produce diol esters other than direct esterification of diols.

33. 发明申请

WO2019229239A1 IONIC METAL ALKYLIDENE COMPOUNDS AND USE THEREOF IN OLEFINIC METATHESIS REACTIONS 审中-公开
公开(公告)号：WO2019229239A1
公开(公告)日：2019-12-05
申请号：PCT/EP2019/064192
申请日：2019-05-31
申请人： VERBIO VEREINIGTE BIOENERGIE AG
发明人： ONDI, Levente , SCHOWNER, Roman , BUCHMEISER, Michael R. , ELSER, Iris , TÓTH, Flórián , ROBE, Emmanuel , VAKULYA, Benedek
IPC分类号： C07F11/00 , C07D207/48 , C07F5/02 , C07B47/00 , C07D333/06 , C07C67/293 , C07C67/333 , C07C67/475 , C07C303/40 , C07B37/10 , C07C209/68 , C07C319/20 , C07C6/04 , C07C253/30
摘要： A compound of formula (I) wherein: M is selected from Mo or W; X is selected from O or NR 5 ; R 1 and R 2 are independently selected from H, C 1-6 alkyl, and aryl; C 1-6 alkyl and aryl optionally being substituted with one or more of C 1-6 alkyl, C 1-6 alkoxy, and O-C 6 H 5 ; R 3 is selected from a nitrogen-containing aromatic heterocycle being bound to M via said nitrogen; and from halogen; R 4 is an aryl oxy group being bound to M via said oxygen of said aryl oxy group; wherein said aryl group Ar of said aryl oxy group is bound to a group Cat such to form a cationic ligand Cat + -Z-ArO-, wherein Z is either a covalent bond or a linker; R 5 is alkyl or aryl, optionally substituted.

34. 发明申请

WO2018038742A1 MECHANOCHEMICAL SYNTHESIS OF IPTYCENES 审中-公开
标题翻译：机械合成IPTYCENES
公开(公告)号：WO2018038742A1
公开(公告)日：2018-03-01
申请号：PCT/US2016/049043
申请日：2016-08-26
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人： SWAGER, Timothy, M. , ZHAO, Yanchuan , VELEIRINHO DE OLIVEIRA ROCHA, Silvia
IPC分类号： C07C45/69 , C07C49/665 , C07C67/00 , C07C67/293 , C07C69/28 , C07C69/33 , C07C69/533 , C07C69/608 , C07C69/78 , C07C303/26 , C07C309/73 , C08G61/02 , B01D39/00 , C07B37/12 , C07F7/18
CPC分类号： C07C45/69 , C07C67/00 , C07C67/293 , C07C69/28 , C07C69/33 , C07C69/533 , C07C69/608 , C07C69/78 , C07C303/26 , C07C309/73 , C07C2603/74 , C07C2603/90 , C07C49/665
摘要： Compositions comprising bridged bicyclic-based compounds such as iptycene-based compounds and methods for mechanochemically synthesizing them are generally provided. In some cases, two or more polycyclic aromatic hydrocarbons may be mechanochemically reacted such that the product comprises the bridged bicyclic-based compound. In some embodiments, the product may comprise two or more [2.2.2] bicyclic cores. In certain embodiments, the mechanochemical reactions described herein may produce higher order bridged bicyclic-based compounds such as oligoiptycenes or poly-iptycenes. In certain embodiments, the bridged bicyclic based compound comprises a molecular cage. Filter devices comprising such compounds are also disclosed.
摘要翻译：通常提供包含基于桥联双环的化合物如基于简便型化合物的组合物和用于机械化学合成它们的方法。在一些情况下，两种或更多种多环芳烃可以机械化学反应，使得产物包含桥接的二环基化合物。在一些实施方案中，产物可以包含两个或更多个[2.2.2]双环核心。在某些实施方案中，本文所述的机械化学反应可以产生更高级的基于桥联双环的化合物，例如低聚庚烯或聚 - 椰子基。在某些实施方案中，桥连双环基化合物包含分子笼。还公开了包含这种化合物的过滤装置。

35. 发明申请

WO2015142549A1 LOW-PRESSURE SYNTHESIS OF CYCLOHEXANEDIMETHANOL AND DERIVATIVES 审中-公开
标题翻译：环丙烷二甲醇和衍生物的低压合成
公开(公告)号：WO2015142549A1
公开(公告)日：2015-09-24
申请号：PCT/US2015/019365
申请日：2015-03-09
申请人： EASTMAN CHEMICAL COMPANY
发明人： BOONE, Matthew, Allen , HEMBRE, Robert, Thomas
IPC分类号： C07C29/17 , C07C29/44 , C07C67/283 , C07C67/293 , C07F7/18 , C07C31/27 , C07C33/14 , C07C69/16
CPC分类号： C07F7/1896 , C07C29/09 , C07C29/172 , C07C29/46 , C07C41/09 , C07C41/20 , C07C41/30 , C07C67/08 , C07C67/283 , C07C67/293 , C07C2601/14 , C07C2601/16 , C07F7/1872 , C07C69/16 , C07C33/14 , C07C31/276
摘要： The invention is directed to a process for preparing a 1,4-disubstituted cyclohexane compound of Formula (I): where A is -OH, -OR, Br, or CI; and R is a silyl group, a hydrocarbyl group, or an acyl group having 1 to 12 carbon atoms. The process includes the steps of reacting ethylene with a (2E,4E)-hexa-2,4-diene compound to produce a 3,6-disubstituted cyclohex-1 - ene compound, and hydrogenating the 3,6-disubstituted cyclohex-1 -ene compound to yield the 1,4-disubstituted cyclohexane compound of formula (I).
摘要翻译：本发明涉及制备式（I）的1,4-二取代的环己烷化合物的方法：其中A是-OH，-OR，Br或Cl; R为甲硅烷基，烃基或碳原子数为1〜12的酰基。该方法包括使乙烯与（2E，4E） - 六-2,4-二烯化合物反应以产生3,6-二取代的环己-1-烯化合物和氢化3,6-二取代的环己-1-烯烯化合物，得到式（I）的1,4-二取代的环己烷化合物。

36. 发明申请

WO2005069998A2 NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME 审中-公开
标题翻译：新型SIRTUIN激活化合物及其制备方法
公开(公告)号：WO2005069998A2
公开(公告)日：2005-08-04
申请号：PCT/US2005/002229
申请日：2005-01-19
申请人： BRIGHAM YOUNG UNIVERSITY TECHNOLOGY TRANSFER OFFICE , ANDRUS, Merritt, B. , LIU, Jing
发明人： ANDRUS, Merritt, B. , LIU, Jing
IPC分类号： C07C67/08 , C07C67/29 , C07C67/293 , C07C69/017
CPC分类号： C07C69/017 , C07C67/08 , C07C67/14 , C07C67/287 , C07C67/29 , C07C67/293 , Y02P20/55 , C07C69/716 , C07C69/63 , C07C69/18 , C07C69/16
摘要： The present invention includes methods for preparing resveratrol, resveratrol esters and substituted and unsubstituted stilbenes of the formula given below; where each Y is -O or halogen, each Z is -O or halogen, each n and each m is independently the value of 0, 1, 2, 3, 4 or 5, each A and each B is independently selected from P n , R or absent, each V and each W is independently selected from P n , straight or branched alkyl of from (2) to (6) carbon atoms and cycloalkyl of from (3) to (8) carbon atoms, alkoxy, phenyl, benzyl or halogen, R is independently selected from the group comprising alkyl with at least one carbon atom, aryl and aralkyl, P n is an alcohol protecting group and diastereoisomers of the foregoing. The compounds are made from a multi-step process including a N-heterocyclic carbene-type ligand coupling in the presence of a base with benzyol halide and styrene coupling partners. These compounds show increased stability for use in the food, cosmetic and pharmaceutical industries.
摘要翻译：本发明包括用于制备下列给出的式的白藜芦醇，白藜芦醇酯和取代和未取代的二苯乙烯的方法; 其中每个Y是-O或卤素，每个Z是-O或卤素，每个n和每个m独立地是0,1,2,3,4或5的值，每个A和每个B独立地选自Pn， R或不存在，每个V和每个W独立地选自（2）至（6）个碳原子的直链或支链烷基，（3）至（8）碳原子的烷基，烷氧基，苯基，苄基或卤素，R独立地选自烷基与至少一个碳原子的基团，芳基和芳烷基，Pn是醇保护基和前述的非对映异构体。所述化合物由多步法制备，包括在碱存在下与苄氧基卤化物和苯乙烯偶合物偶联的N-杂环卡宾型配体偶联。这些化合物在食品，化妆品和制药工业中显示出增加的稳定性。

37. 发明申请

WO2005026142A3 SYNTHESIS OF ALPHA-TOCOPHERYL ALKANOATES AND PRECURSORS THEREOF 审中-公开
标题翻译： ALPHA-TOCOPHERYL ALKANOATES及其前体的合成
公开(公告)号：WO2005026142A3
公开(公告)日：2005-06-09
申请号：PCT/EP2004009749
申请日：2004-09-02
申请人： DSM IP ASSETS BV , BONRATH WERNER , BREUNINGER MANFRED , MALAISE GREGORY , NETSCHER THOMAS
发明人： BONRATH WERNER , BREUNINGER MANFRED , MALAISE GREGORY , NETSCHER THOMAS
IPC分类号： C07C67/28 , C07C67/293 , C07C69/017 , C07D311/72 , C07C69/157 , C07C69/16
CPC分类号： C07C69/017 , C07C67/08 , C07C67/28 , C07C67/29 , C07C67/293 , C07C67/475 , C07C69/157 , C07D311/72 , C07C69/16 , C07C69/145 , C07C69/07 , C07C69/78 , C07C69/007
摘要： The present invention is concerned with a novel process for the manufacture of 4alkanoyloxy-2,3,5-trimethylphenyI (E/Z)-phytyl ethers, precursors of alpha.-tocopheryl alkanoates, by cross-metathesis reaction of alkenyl ethers of 1-alkanoyloxy-2,3,6-trimethylhydroquinone with 2,6,10,14-tetramethylpentadecene or a phytol derivative, e.g. an ester, an ether or a silyl ether, in the presence of a cross-metathesis catalyst. As the crossmetathesis catalyst especially ruthenium metal carbene complexes are suitable which possess (a) ruthenium metal center(s), have an electron count of 16 or 18 and are penta- or hexa- coordinated. A further object of the invention is a process for the manufacture of alphatocopheryl alkanoates comprising this reaction.
摘要翻译：本发明涉及一种制备4-烷酰氧基-2,3,5-三甲基苯基（E / Z） - 萜醚的新颖方法，其是α-烯烃 - 生育酚链烷酸酯的前体，通过1- 链烷酰氧基-2,3,6-三甲基氢醌与2,6,10,14-四甲基十五碳烯或植醇衍生物，例如酯，醚或甲硅烷基醚，在交叉复分解催化剂存在下进行。由于具有（a）钌金属中心的交叉分析催化剂特别是钌金属卡宾络合物是合适的，其电子数为16或18，并且是五元或六配位的。本发明的另一个目的是制备包含该反应的链烷酸α-生育脂基的方法。

38. 发明申请

WO2003051814A1 PYRROLSYNTHESE 审中-公开
标题翻译：吡咯
公开(公告)号：WO2003051814A1
公开(公告)日：2003-06-26
申请号：PCT/EP2002/013152
申请日：2002-11-22
申请人： MERCK PATENT GMBH , WÄCHTLER, Andreas , WELZ-BIERMANN, Urs , DE MEIJERE, Armin , FRIEDRICH, Marko
发明人： WÄCHTLER, Andreas , WELZ-BIERMANN, Urs , DE MEIJERE, Armin , FRIEDRICH, Marko
IPC分类号： C07C67/293
CPC分类号： C07D207/333
摘要： Gegenstand der vorliegenden Erfindung sind Verbindungen gemäss Formel (I), deren Verwendung zur Herstellung von Pyrrolen der Formel (II), sowie entsprechende Herstellverfahren.
摘要翻译：本发明的根据式（I），它们的对式（II）的吡咯的制备中使用，以及相应的制造方法涉及的化合物。

39. 发明申请

WO02100323A2 METHYL ANALOGS OF SIMVASTATIN AS NOVEL HMG-CoA REDUCTASE INHIBITORS 审中-公开
标题翻译：辛伐他汀作为新型HMG-CoA还原酶抑制剂的甲基化学
公开(公告)号：WO02100323A2
公开(公告)日：2002-12-19
申请号：PCT/IB0202112
申请日：2002-06-10
申请人： RANBAXY LAB LTD , THAPER RAJESH KUMAR , KUMAR SARIDI MADHAVA DILEEP , KUMAR YATENDRA
发明人： THAPER RAJESH KUMAR , KUMAR SARIDI MADHAVA DILEEP
IPC分类号： A61K31/22 , A61K31/366 , A61P3/06 , A61P9/00 , C07C67/293 , C07C67/52 , C07C67/58 , C07C69/013 , C07C69/03 , C07C69/30 , C07D309/30 , A61K
CPC分类号： C07C69/30 , C07C2602/28 , C07D309/30
摘要： The present invention relates to a novel methyl analog of simvastatin, which has the ability to inhibit the synthesis of cholesterol. The compound of the present invention holds promise for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders. The invention also relates to a process for making the novel compound.
摘要翻译：本发明涉及辛伐他汀的新型甲基类似物，其具有抑制胆固醇合成的能力。本发明的化合物具有治疗和预防高胆固醇血症和各种心脏病的希望。本发明还涉及制备该新化合物的方法。

40. 发明申请

WO02002500A1 PREPARATION OF (R)-2-ALKYL-3-PHENYLPROPIONIC ACIDS. 审中-公开
标题翻译：（R）-2-烷基-3-苯基丙酸的制备。
公开(公告)号：WO02002500A1
公开(公告)日：2002-01-10
申请号：PCT/CH2001/000397
申请日：2001-06-26
IPC分类号： B01J31/24 , C07B53/00 , C07B61/00 , C07C51/36 , C07C59/64 , C07C59/66 , C07C62/34 , C07C67/293
CPC分类号： C07C59/66 , C07C51/36
摘要： Compounds of formula (I), wherein R1 and R2 are, independently of one another, H, C1-C6alkyl, C1-C6halogenalkyl, C1-C6alkoxy, C1-C6alkoxy-C1-C6alkyl, or C1-C6alkoxy-C1-C6alkyloxy, and R3 is C1-C6alkyl, are obtainable in high yields by stereoselective addition of R3-substituted propionic acid esters to R1- and R2-substituted benzaldehydes of formula R-CHO to form corresponding 3-R-3-hydroxy-2-R3-propionic acid esters, conversion of the OH group to a leavaing group, subsequent regioselective elimination to form 3-R-2-R3-propenic acid esters, and their hydrolysis to form corresponding propenic carboxylic acids and their enantioselective hydrogenation, wherein R is (a).
摘要翻译：式（I）化合物，其中R 1和R 2彼此独立地为H，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 1 -C 6烷氧基，C 1 -C 6烷氧基-C 1 -C 6烷基或C 1 -C 6烷氧基-C 1 -C 6烷氧基， R 3是C 1 -C 6烷基，可以通过立体选择性地将R 3取代的丙酸酯加成到式R-CHO的R 1和R 2取代的苯甲醛以高产率获得，形成相应的3-R-3-羟基-2-R3-丙酸酸酯，OH基转化为脱氯基团，随后进行区域选择性消除以形成3-R-2-R3-丙烯酸酯，并且它们的水解形成相应的丙烯羧酸及其对映选择性氢化，其中R为（a）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式