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31. 发明申请

WO2016083380A1 MECHANISM FOR SETTING A MAXIMUM DOSE OF A MEDICAMENT FOR A VARIABLE DOSE DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于设定用于可变剂量药物递送装置的药物的最大剂量的机构
公开(公告)号：WO2016083380A1
公开(公告)日：2016-06-02
申请号：PCT/EP2015/077512
申请日：2015-11-24
申请人： SANOFI
发明人： AVERY, Richard James Vincent , JONES, Matthew Meredith , MARSH, William Geoffrey Arthur , MORRIS, Anthony Paul , PLUMPTRE, Dave Aubrey , STEEL, Samuel Keir , SENIOR, James Alexander , VEASEY, Robert Frederick
IPC分类号： A61M5/20 , A61M5/315 , A61M5/31
CPC分类号： A61M5/31538 , A61M5/20 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31561 , A61M5/3157 , A61M5/31583 , A61M5/31585 , A61M5/329 , A61M2005/3126 , A61M2005/3154 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： The present invention concerns a mechanism for setting a dose of a medicament for a variable dose drug delivery device, comprising: a housing (10), a sleeve component (60) configured to rotate relative to the housing (10) during a dose setting operation, and a stop member (200) which is configured to limit a total amount of possible rotation of the sleeve component (60) to a maximum and, thereby, to limit a maximum settable dose, wherein the stop member (200) is configured to allow varying the maximum which determines the total amount of possible rotation of the sleeve component.
摘要翻译：本发明涉及一种用于设定可变剂量药物递送装置的药物剂量的机构，包括：壳体（10），套筒部件（60），其构造成在剂量设定操作期间相对于壳体（10）旋转，以及止动构件（200），其被构造成将所述套筒构件（60）的可能旋转的总量限制到最大值，从而限制最大可设定剂量，其中所述止动构件（200）构造成允许改变确定套筒部件可能旋转的总量的最大值。

32. 发明申请

WO2012146677A1 LOCKOUT ELEMENT FOR DISPENSE INTERFACE 审中-公开
标题翻译：用于歧视界面的锁定元件
公开(公告)号：WO2012146677A1
公开(公告)日：2012-11-01
申请号：PCT/EP2012/057692
申请日：2012-04-26
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , HOLTWICK, Marc , EGGERT, Ilona , DAVIES, James Alexander , BILTON, Simon Lewis , MOORE, David , WIMPENNY, Steven , LANGLEY, Christopher Nigel
发明人： HOLTWICK, Marc , EGGERT, Ilona , DAVIES, James Alexander , BILTON, Simon Lewis , MOORE, David , WIMPENNY, Steven , LANGLEY, Christopher Nigel
IPC分类号： A61M5/50 , A61M5/34 , A61M5/19 , A61M5/00
CPC分类号： A61M5/50 , A61M5/19 , A61M5/31535 , A61M5/31538 , A61M5/34
摘要： The invention is related to an apparatus comprising a dispense interface (1200, 5025, 6205) for use with a drug delivery device, the dispense interface (1200, 5025, 6205) comprising a lockout element (5000, 5600, 6200) being arranged at least partially between an outer body (1210) of the dispense interface (1200, 5025, 6205) and an inner body (2000) of the dispense interface (1200, 5025, 6205) and wherein the lockout element (5000, 5200, 5600, 6200) is configured to be removeably maintained in a first position, such that when the dispense interface (1200, 5025, 6205) is first attached and then removed from said drug delivery device, the lockout element (5000, 5200, 5600, 6200) moves into a second position, wherein the lockout element (5000, 5200, 5600, 6200) in the second position is configured to prevent said dispense interface (1200, 025, 6205) from being reattached to a drug delivery device.
摘要翻译：本发明涉及一种包括用于药物输送装置的分注界面（1200,5025,6205）的装置，所述分配界面（1200,5025,6205）包括锁定元件（5000,5600,6200）至少部分地在分配界面（1200,5025,6205）的外主体（1210）和分配接口（1200,5025,6205）的内体（2000）之间，并且其中所述锁定元件（5000,5200,5600， 6200）构造成可移除地保持在第一位置，使得当分配界面（1200,5025,6205）首先被附接并且然后从所述药物输送装置移除时，锁定元件（5000,5200,5600,6200）移动到第二位置，其中处于第二位置的锁定元件（5000,5200,5600,6200）被配置为防止所述分配接口（1200,025,6205）重新附接到药物递送装置。

33. 发明申请

WO2012049140A1 DOSE SETTING MECHANISM AND METHOD OF USING SAME 审中-公开
标题翻译：剂量设定机构及其使用方法
公开(公告)号：WO2012049140A1
公开(公告)日：2012-04-19
申请号：PCT/EP2011/067677
申请日：2011-10-11
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , LEAK, David Martin , BUTLER, Joseph
发明人： LEAK, David Martin , BUTLER, Joseph
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/31525 , A61M5/31538 , A61M5/31551 , A61M5/31571 , A61M5/31585
摘要： The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a drug delivery device housing (17), a dose dial sleeve (9) positioned at least partly in the housing (17) and being rotatable during dose setting and dose delivery, a clutch (13) rotatable during dose setting and non-rotatable during dose delivery, and a clutch nut (15), that is threadedly engaged with the clutch (13) and is splined to the housing (17) to prevent rotation of the clutch nut (15).
摘要翻译：本发明涉及药物输送装置的剂量设定机构及其使用方法。所述机构包括药物输送装置壳体（17），剂量拨轮套筒（9），其至少部分地定位在所述壳体（17）中并且在剂量设定和剂量递送期间可旋转;离合器（13）以及离合器螺母（15），其与离合器（13）螺纹接合并且花键连接到壳体（17）以防止离合器螺母（15）的旋转。

34. 发明申请

WO2010139638A1 DOSING MECHANISM FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的剂量机制
公开(公告)号：WO2010139638A1
公开(公告)日：2010-12-09
申请号：PCT/EP2010/057484
申请日：2010-05-28
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , JONES, Christopher
发明人： JONES, Christopher
IPC分类号： A61M5/315 , A61M5/00
CPC分类号： A61M5/31538 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31545 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/31595 , A61M2005/3154
摘要： A maximum settable dose feature is disclosed that is set by a user or health care professional one time that prevents future injections from exceeding the desired maximum dose. The feature includes a locking band (5) initially in an unlocked configuration, which transforms to a locked configuration when activated after setting a desired maximum dose. The feature can include a trigger mechanism (6, 11) to transform the locking band (5) to the locked configuration.
摘要翻译：公开了由用户或保健专业人员设定的一次可防止未来注射超过所需最大剂量的最大可设定剂量特征。该特征包括最初处于未锁定配置的锁定带（5），当在设定期望的最大剂量之后激活时，锁定配置变换为锁定配置。该特征可以包括将锁定带（5）变换成锁定构造的触发机构（6,11）。

35. 发明申请

WO2006079900A8 INJECTION DEVICE FOR ADMINISTERING A MEDICATION LIQUID 审中-公开
标题翻译：用于管理药液的注射装置
公开(公告)号：WO2006079900A8
公开(公告)日：2007-03-29
申请号：PCT/IB2006000123
申请日：2006-01-12
申请人： PHARMACIA CORP , HJERTMAN BIRGER THURE YNGVAR , JAEGER HANS , MAYOR LAETITIA
发明人： HJERTMAN BIRGER THURE YNGVAR , JAEGER HANS , MAYOR LAETITIA
IPC分类号： A61M5/315 , A61M5/24 , A61M5/50
CPC分类号： A61M5/3155 , A61M5/2448 , A61M5/3146 , A61M5/31538 , A61M5/31555 , A61M5/31563 , A61M5/3158 , A61M5/5013 , A61M5/502 , A61M2005/5033
摘要： Multiple dose disposable injection device (1) for reconstituting a medication liquid before its injection and for permanently adjusting the volume of the doses of medication liquid to be administered. The injection device (1) is additionally totally undemountable after the final use.
摘要翻译：多剂量一次性注射装置（1），用于在注射前重建药物液体，并用于永久调节待施用的药物液体的剂量的体积。在最终使用后，注射装置（1）另外完全不可重复。

36. 发明申请

WO2006125328A1 DOSIERVORRICHTUNG FÜR EINE INJEKTIONSVORRICHTUNG 审中-公开
标题翻译：给药用于注射装置
公开(公告)号：WO2006125328A1
公开(公告)日：2006-11-30
申请号：PCT/CH2006/000237
申请日：2006-04-28
申请人： TECPHARMA LICENSING AG , BURREN, Stefan , MOSER, Ulrich , SCHRUL, Christian
发明人： BURREN, Stefan , MOSER, Ulrich , SCHRUL, Christian
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31585 , A61M5/24 , A61M5/31535 , A61M5/31536 , A61M5/31538 , A61M5/31541 , A61M5/31553 , A61M5/31563 , A61M5/31575 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： Die vorliegende Erfindung betrifft eine Dosiervorrichtung zur Einstellung einer aus einer Injektionsvorrichtung (1) abzugebenden Dosis mit einem Einstellelement, insbesondere einer Einstellhülse (2), und einem Aufziehelement, insbesondere einer Drehhülse (3), das aus der Dosiervorrichtung (1) zur Vorbereitung einer Dosisabgabe herausgedreht werden kann, wobei auf dem Einstellelement (2) ein Anschlag (2b) und auf dem Aufziehelement (3) ein Gegenanschlag (3g) angebracht ist, so dass eine Drehbewegung des Aufziehelements (3) relativ zum Einstellelement (2) durch die Anschläge (2b, 3g) begrenzt werden kann, sowie ein Verfahren zum Einstellen einer Dosis, welche aus einer Injektionsvorrichtung (1) abgegeben werden soll, wobei die abzugebende Dosis mit einem Einstellelement, insbesondere einer Einstellhülse (2), eingestellt werden kann und anschließend die Injektionsvorrichtung (1) mit einem Aufziehelement, insbesondere einer Drehhülse (3), durch eine Drehbewegung aufgezogen werden kann, um in einem anschließenden Schritt die eingestellte Dosis aus der Injektionsvorrichtung (1) abzugeben, wobei der Einstellvorgang von dem Aufziehvorgang entkoppelt ist.
摘要翻译：本发明涉及一种配料装置，用于设置的注射装置的一（1）剂量为与调节元件的管（2），和一个填充元件，尤其是旋转套筒从所述计量装置（1）用于制备剂量递送（3）被分配，特别是可旋转，其特征在于，一个止动件（2b）和填充元件（3）上的计数器停止（3G）被安装在调节元件（2）上，从而使Aufziehelements（3）相对于所述调节元件（2）由所述止挡的旋转运动（如图2B所示，3G）可以被限制，并且对于管（2）设置，其（注射装置1）待分配的，所分配的剂量可与调节元件调节的剂量，特别是一种方法，然后将注射装置（ 1）用填充元件，特别是旋转被通过旋转运动卷绕根套管（3） n至在后续步骤中分配来自所述注射装置（1），其中所述调整是从安装过程解耦设定剂量。

37. 发明申请

WO2006080893A1 DEVICE FOR DELIVERING MEDICAMENT 审中-公开
标题翻译：用于输送药物的装置
公开(公告)号：WO2006080893A1
公开(公告)日：2006-08-03
申请号：PCT/SE2006/000135
申请日：2006-01-31
申请人： SHL MEDICAL AB , BOSTRÖM, Anders , OLSON, Stephan , BRUNNBERG, Lennart
发明人： BOSTRÖM, Anders , OLSON, Stephan , BRUNNBERG, Lennart
IPC分类号： A61M5/20
CPC分类号： A61M5/31501 , A61M5/2033 , A61M5/2066 , A61M5/2448 , A61M5/3146 , A61M5/31538 , A61M2005/2013
摘要： The present invention relates to a device for delivery of medicament comprising a main housing, a container including at least two compartments, wherein each compartment contains a component of the medicament to be injected, and arranged to be connected to a patient delivery means, a longitudinally movable piston and a spring arrangement acting on said piston and capable of exerting a force on said components, a first holding means arranged and capable of holding said piston in a force-loaded state, and at least one activator means capable of acting on said first holding means for releasing said piston, characterised in that it further comprises a second holding means capable of stopping the movement of said piston when it has moved a certain first distance after one activation of the at least one activator means and holding said piston in that position, wherein the force from the piston/spring arrangement and the movement causes the compartments to communicate with each other and the components to mix, in that said at least one activator means is capable of acting on said second holding means for releasing said piston, and wherein, upon a subsequent activation of said at least one activator means, the piston moves a certain second distance, wherein the force from the piston/spring arrangement and the movement causes the mixed components to be ejected through the patient delivery means.
摘要翻译：本发明涉及一种用于输送药物的装置，包括主壳体，包括至少两个隔室的容器，其中每个隔室包含待注射的药物的部件，并且布置成连接到患者输送装置，纵向可移动活塞和作用在所述活塞上并且能够对所述部件施加力的弹簧装置，布置并能够将所述活塞保持在加载力状态的第一保持装置，以及能够作用在所述第一用于释放所述活塞的保持装置，其特征在于，还包括第二保持装置，其能够在所述至少一个致动器装置的一个启动之后移动一定的第一距离并且将所述活塞保持在该位置时停止所述活塞的移动，其中来自活塞/弹簧装置的力和运动导致隔室彼此连通所述至少一个活化器装置能够作用在所述第二保持装置上用于释放所述活塞，并且其中，在随后激活所述至少一个活化器装置时，所述活塞移动一定的第二距离，其中来自活塞/弹簧装置的力和移动导致混合的部件通过患者输送装置排出。

38. 发明申请

WO2004073621A3 DRUG DELIVERY SYSTEM FOR ADMINISTERING AN ADJUSTABLE PRESET DOSE 审中-公开
标题翻译：用于管理可调节预置剂量的药物输送系统
公开(公告)号：WO2004073621A3
公开(公告)日：2005-06-02
申请号：PCT/US2004004297
申请日：2004-02-11
申请人： XCEL PHARMACEUTICALS INC , HORVATH MICHAEL W , JENSEN DAVID F , SPONSEL MARK R , ROSSI JOSEPH P , MALONE GREGORY D
发明人： HORVATH MICHAEL W , JENSEN DAVID F , SPONSEL MARK R , ROSSI JOSEPH P , MALONE GREGORY D
IPC分类号： A61M5/31 , A61M5/315 , A61M5/00
CPC分类号： A61M5/31591 , A61M5/31505 , A61M5/31538 , A61M5/31548 , A61M5/31551 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/3158 , A61M2005/312 , A61M2005/3125 , A61M2005/3154 , A61M2205/583
摘要： An embodiment of the present invention provides an apparatus for setting a dose of a drug in a syringe having a plunger, comprising an outer housing (202) and an inner housing (200) adapted for encircling the syringe (10), such that the inner housing (200) is positioned within the outer housing (202) to set the dose of the drug. In an embodiment, the apparatus further comprises a dosage indicator (1012) disposed on the inner housing (200) and the outer housing (202) further comprises an opening for viewing the dosage indicator (1012).
摘要翻译：本发明的一个实施例提供了一种用于设置具有柱塞的注射器中的药物剂量的装置，其包括外壳（202）和适于环绕注射器（10）的内壳（200），使得内壳体（200）位于外壳体（202）内以设定药物的剂量。在一个实施例中，该装置还包括设置在内壳体（200）上的剂量指示器（1012），外壳体（202）还包括用于观察剂量指示器（1012）的开口。

39. 发明申请

WO02030495A2 PEN DEVICE FOR ADMINISTRATION OF PARATHYROID HORMONE 审中-公开
标题翻译： PEN装置用于管理PARATHYROID HORMONE
公开(公告)号：WO02030495A2
公开(公告)日：2002-04-18
申请号：PCT/US2001/027732
申请日：2001-09-26
IPC分类号： A61M5/24 , A61M5/31 , A61M5/315
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/3146 , A61M5/31538 , A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M2005/3125 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/585
摘要： A pen delivery device and a procedure for administering parathyroid hormone is provided to allow for the priming and injection of a single predetermined dose. The method is a three-step method using visual indicators to set the priming and injectable dose deliveries. The device is made of a minimal number of parts, which include a housing, a dose knob, a generally cylindrical disengaging assembly located within the proximal end of the dose knob, and an externally threaded drive stem. The pen device further includes a mechanism that prevents the user from dialing up a dosage greater than that remaining in the cartridge.
摘要翻译：提供笔输送装置和用于施用甲状旁腺激素的程序以允许引发和注射单一预定剂量。该方法是使用视觉指示剂设置灌注和注射剂量递送的三步法。该装置由最少数量的部件制成，其包括壳体，剂量旋钮，位于剂量旋钮的近端内的大致圆柱形的分离组件和外螺纹的驱动杆。笔装置还包括防止用户拨打比剩余在盒中的剂量更大的剂量的机构。

40. 发明申请

WO1992018179A1 INJECTION DEVICE 审中-公开
标题翻译：注射装置
公开(公告)号：WO1992018179A1
公开(公告)日：1992-10-29
申请号：PCT/EP1992000831
申请日：1992-04-13
申请人： MEDICO DEVELOPMENT INVESTMENT COMPANY , GABRIEL, Jochen
发明人： MEDICO DEVELOPMENT INVESTMENT COMPANY
IPC分类号： A61M05/315
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31535 , A61M5/31538 , A61M5/31553 , A61M5/31563 , A61M5/31593 , A61M2205/581
摘要： The injection device proposed comprises a housing (11, 21) designed to hold the liquid to be injected. Fitted in this housing is a plunger (29, 38) which can be moved longitudinally. When injecting, the plunger is displaced between an active position and an inactive position, thus pushing the liquid (13) out of the housing. A control member (23) is fitted, by means of which the effective length of the plunger (29, 38) can be altered. In the inactive position, the plunger-length adjustment mechanism using the control member (23) is not activated, and hence adjustment of the dose is not possible in this position. Operator errors are therefore avoided.

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