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31. 发明申请

WO2009024819A1 CANNABINOID RECEPTOR LIGANDS 审中-公开
标题翻译： CANNABINOID受体配体
公开(公告)号：WO2009024819A1
公开(公告)日：2009-02-26
申请号：PCT/GB2008/050713
申请日：2008-08-15
申请人： ASTRAZENECA AB , ASTRAZENECA UK LIMITED , BEHA, Sara , BROWN, William , JOHNSTONE, Shawn , LIU, Ziping , PAGÈ, Daniel , TOMASZEWSKI, Miroslaw , WEI, Zhong-yong , YUE, Shi Yi
发明人： BEHA, Sara , BROWN, William , JOHNSTONE, Shawn , LIU, Ziping , PAGÈ, Daniel , TOMASZEWSKI, Miroslaw , WEI, Zhong-yong , YUE, Shi Yi
IPC分类号： C07D405/04 , C07D405/14
CPC分类号： C07D405/04 , C07D405/14
摘要： Compounds of Formulae (I), or pharmaceutically acceptable salts thereof: wherein R 1 , R 2 and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：式（I）化合物或其药学上可接受的盐：其中R1，R2和Y如本说明书中所定义，以及包括该化合物的盐和药物组合物的制备。它们可用于治疗，特别是治疗疼痛。

32. 发明申请

WO2008033478A1 WIRELESS VOIP HEADSET WITH CALL ORIGINATION CAPABILITY 审中-公开
标题翻译：无线电话耳机具有呼叫发起能力
公开(公告)号：WO2008033478A1
公开(公告)日：2008-03-20
申请号：PCT/US2007/019958
申请日：2007-09-13
申请人： PLANTRONICS, INC. , REUSS, Edward , BROWN, William , FILIMON, Cristian , ALTMANN, Alan , GILES, Rick
发明人： REUSS, Edward , BROWN, William , FILIMON, Cristian , ALTMANN, Alan , GILES, Rick
IPC分类号： H04M1/60 , H04M1/253
CPC分类号： H04M1/271 , H04M1/05 , H04M1/2535 , H04M1/6066
摘要： Systems and methods for a wireless VoIP headset. A wireless VoIP headset including a speaker, microphone, controller for processing a digital audio signal to generate IP packets, and an IEEE 802.11 transceiver. The wireless VoIP headset includes a computer readable memory storing instructions that when executed by the controller cause the wireless VoIP headset to perform a method for originating a call. The method includes receiving a spoken name or number from a user at the microphone, interpreting the spoken name or number using embedded or server based voice recognition, comparing the spoken name or number to a directory stored in the computer readable memory, and generating a call origination request message. The directory may also be stored on an adjunct computing device.
摘要翻译：无线VoIP耳机的系统和方法。包括用于处理数字音频信号以产生IP分组的扬声器，麦克风，控制器的无线VoIP耳机以及IEEE 802.11收发器。无线VoIP耳机包括存储指令的计算机可读存储器，当指令由控制器执行时，无线VoIP耳机执行发起呼叫的方法。该方法包括从麦克风的用户接收口语名称或号码，使用基于嵌入式或基于服务器的语音识别来解释口语名称或号码，将口语名称或号码与存储在计算机可读存储器中的目录进行比较，以及生成呼叫发起请求消息。目录也可以存储在辅助计算设备上。

33. 发明申请

WO2008018827A8 BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATMENT OF VALLINOID RECEPTOR TRPV1 RELATED DISORDERS 审中-公开
公开(公告)号：WO2008018827A8
公开(公告)日：2008-02-14
申请号：PCT/SE2007/000720
申请日：2007-08-10
申请人： ASTRAZENECA AB , BROWN, William , JOHNSTONE, Shawn , LABRECQUE, Denis
发明人： BROWN, William , JOHNSTONE, Shawn , LABRECQUE, Denis
IPC分类号： C07D235/06 , A61K31/4184 , A61P1/04 , A61P13/10 , A61P19/02 , A61P25/00 , A61P29/00
摘要： The claimed invention provides benzimidazole derivatives antagonists of VR1, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I may be used in the treatment of osteoarthritis, chronic tendinitis, pelvic pain and peripheral neuropathy, gastroesophageal reflux disease, irritable bowel syndrome and overactive bladder.

34. 发明申请

WO2007147126A2 WIRELESS AMBULATORY GASTROINTESTINAL MONITORING SYSTEM 审中-公开
标题翻译：无线智能气象监测系统
公开(公告)号：WO2007147126A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/071359
申请日：2007-06-15
申请人： ALPINE BIOMED CORP. , BROWN, William , WESTCOTT, Brad , LUONG, Khai, Si , SAWYER, Jeff
发明人： BROWN, William , WESTCOTT, Brad , LUONG, Khai, Si , SAWYER, Jeff
IPC分类号： A61B5/103 , A61B5/05 , A61B5/00
CPC分类号： A61B5/0002 , A61B5/037 , A61B5/053 , A61B5/14539 , A61B5/4211 , A61B5/6882 , A61B2562/0247 , A61B2562/043
摘要： A wireless ambulatory reflux monitoring system capable of monitoring and recording esophageal biological parameters during an ambulatory period. The wireless ambulatory reflux monitoring system is further capable of recording perceived reflux events at the discretion of a patient contemporaneously with the recording of biological data.
摘要翻译：一种能够在动态期间监测和记录食管生物学参数的无线移动式回流监测系统。无线移动式回流监测系统还能够在患者同时记录生物数据的情况下记录感觉到的反流事件。

35. 发明申请

WO2006014133A1 DIARYLMETHYL PIPERAZINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF 审中-公开
标题翻译：二甲基哌嗪衍生物，其制备及其用途
公开(公告)号：WO2006014133A1
公开(公告)日：2006-02-09
申请号：PCT/SE2005/001186
申请日：2005-07-27
申请人： AstraZeneca AB , BROWN, William , GRIFFIN, Andrew , HUDZIK, Thomas , MACIAG, Carla , SMAGIN, Gennady , WALPOLE, Christopher
发明人： BROWN, William , GRIFFIN, Andrew , HUDZIK, Thomas , MACIAG, Carla , SMAGIN, Gennady , WALPOLE, Christopher
IPC分类号： C07D295/155
CPC分类号： C07D295/145 , C07D295/155
摘要： Compounds of general formula: , as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain, depression and anxiety.
摘要翻译：制备通式的化合物，以及其盐，对映异构体和包括该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛，抑郁和焦虑。

36. 发明申请

WO2004063157A1 DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF 审中-公开
标题翻译：二甲基苯胺哌啶衍生物，其制备及其用途
公开(公告)号：WO2004063157A1
公开(公告)日：2004-07-29
申请号：PCT/GB2004/000116
申请日：2004-01-13
申请人： ASTRAZENECA AB , ASTRAZENECA UK LIMITED , BROWN, William , GRIFFIN, Andrew , WALPOLE, Christopher
发明人： BROWN, William , GRIFFIN, Andrew , WALPOLE, Christopher
IPC分类号： C07D211/70
CPC分类号： C07D211/70 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula: wherein R 1 , R 2 , R 3 , R 4 , and R 5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：通式的化合物：其中R 1，R 2，R 3，R 4和R 5如说明书中所定义，以及其盐，对映体和药物组合物，包括制备化合物。它们可用于治疗，特别是治疗疼痛。

37. 发明申请

WO2002094785A1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders 审中-公开
标题翻译： 4-（苯基 - （哌啶-4-基） - 氨基） - 苯甲酰胺衍生物及其用于治疗疼痛，焦虑或胃肠道疾病
公开(公告)号：WO2002094785A1
公开(公告)日：2002-11-28
申请号：PCT/SE2002/000957
申请日：2002-05-16
申请人： ASTRAZENECA AB , BROWN, William , GRIFFIN, Andrew , WALPOLE, Christopher
发明人： BROWN, William , GRIFFIN, Andrew , WALPOLE, Christopher
IPC分类号： C07D211/58
CPC分类号： C07D401/06 , C07D211/58 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula I[Chemical formula should be inserted here. Please see paper copy] R 1 is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, pyrrolyl, triazolyl, thiazolyl and pyridine N-oxide; where each R 1 phenyl ring and R 1 heteroaromatic ring may optionally and independently be further substituted by 1,2 or 3 substituents selected from straight and branched C 1 -C 6 alkyl, NO 2 , CF 3 , C 1 -C 6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain, anxiety and functional gastrointestinal disorders.
摘要翻译：通式Ⅰ化合物[化学式应在此插入。请参见纸张复制] R1选自苯基，吡啶基，噻吩基，呋喃基，咪唑基，吡咯基，三唑基，噻唑基和吡啶N-氧化物中的任一种; 其中每个R 1苯基环和R 1杂芳环可以任选和独立地被1,2或3个选自直链和支链C 1 -C 6烷基，NO 2，CF 3，C 1 -C 6烷氧基，氯，氟，溴和碘的取代基取代。苯环上和杂芳环上的取代可以在所述环体系上的任何位置进行; 在本申请中公开和要求保护，以及包含新化合物的盐和药物组合物及其在治疗中的用途，特别是在治疗疼痛，焦虑和功能性胃肠道疾病中的用途。

38. 发明申请

WO2019023315A2 RAC INHIBITORS 审中-公开
公开(公告)号：WO2019023315A2
公开(公告)日：2019-01-31
申请号：PCT/US2018/043631
申请日：2018-07-25
申请人： GENEYUS LLC , LIPPMAN, Marc , GOKA, Erik , JOHNSTONE, Shawn, D. , BAYRAKDARIAN, Malken , BROWN, William , ALBERT, Jeffrey, S.
发明人： LIPPMAN, Marc , GOKA, Erik , JOHNSTONE, Shawn, D. , BAYRAKDARIAN, Malken , BROWN, William , ALBERT, Jeffrey, S.
摘要： The present invention relates to compounds that act as pan-Rac inhibitors, compositions including the compounds, and methods of using the compounds. In particular, the compounds are useful for treating certain cancers such as breast cancer.

39. 发明申请

WO2010150226A2 METHODS AND SYSTEMS FOR INDEXING ON-DEMAND VIDEO CONTENT IN A CABLE SYSTEM 审中-公开
标题翻译：用于在电缆系统中指示视频内容的方法和系统
公开(公告)号：WO2010150226A2
公开(公告)日：2010-12-29
申请号：PCT/IB2010/052902
申请日：2010-06-24
申请人： ERICSSON TELEVISION INC. , ROBERTSON, Mark , CRICK, David , BROWN, William
发明人： ROBERTSON, Mark , CRICK, David , BROWN, William
IPC分类号： H04N7/173 , G11B27/00 , G11B27/34 , H04N5/445
CPC分类号： H04N7/17336 , G11B27/034 , G11B27/105 , H04N5/44543 , H04N21/2225 , H04N21/23439 , H04N21/26291 , H04N21/472 , H04N21/47202 , H04N21/4788 , H04N21/4828 , H04N21/6125 , H04N21/812 , H04N21/8455 , H04N21/8456 , H04N21/8586
摘要： In one embodiment, an index is created by a first user for a specified video program that is applied when a second user request viewing the specified video program. The index is typically embodied by a file, which identifies one or more content segments of the video program that are not presented to the viewing user. The viewing user selects the program for viewing, typically using a video cm-demand service offered by a cable service provider, and potentially indicates the index file to be applied when viewing the program. The cable service provider streams the video program to the user, but excises the one or more content segments identified in the index file, thus providing a customized viewing experience to the viewing user.
摘要翻译：在一个实施例中，当第二用户请求观看指定的视频节目时，由第一用户创建用于指定的视频节目的索引。索引通常由文件来体现，该文件标识视频节目的一个或多个未呈现给观看用户的内容片段。观看用户通常使用由有线服务提供商提供的视频cm需求服务来选择观看节目，并且可能指示在观看节目时应用的索引文件。有线服务提供商将视频节目流向用户，但是将索引文件中标识的一个或多个内容片段排除，从而为观看用户提供定制的观看体验。

40. 发明申请

WO2009074770A1 SUBSEA CONTAINMENT VESSEL AND HEAT SINK ASSEMBLY 审中-公开
标题翻译： SUBSEA集装船和散热装置
公开(公告)号：WO2009074770A1
公开(公告)日：2009-06-18
申请号：PCT/GB2008/003983
申请日：2008-12-02
申请人： AKER SUBSEA LIMITED , BROWN, William
发明人： BROWN, William
IPC分类号： H02G9/02 , H02G15/14
CPC分类号： H02G9/02 , H02G15/14 , H05K7/1434 , H05K7/20445
摘要： A subsea containment vessel includes a heat sink assembly comprising a cage comprising a plurality of pillars (2) and between at least one pair of adjacent pillars a heat sink in the form of an interface plate (3) having an outer surface for engagement with the containment vessel. The plate has lateral faces each of which has a slanted profile for sliding movement relative to a complementary profile on an adjacent side face of a pillar. The profiles may comprise a rail (6) on a lateral face of the plate and a corresponding slot (7) in an adjacent side face of a pillar (2). Any suitable means may be employed to provide a tensile or compressive force for moving the interface plate into close contact with the vessel. They may include a threaded tumbuckle, a hydraulic piston or a clamp which might be manual and may be self-locking.
摘要翻译：海底安全壳包括散热器组件，其包括包括多个柱（2）的笼和至少一对相邻的柱之间的接合板（3）形式的散热器，所述散热器具有外表面，用于与安全壳板具有侧面，每个侧面具有相对于柱的相邻侧面上的互补轮廓滑动运动的倾斜轮廓。轮廓可以包括在板的侧面上的轨道（6）和在柱（2）的相邻侧面中的相应的狭槽（7）。可以采用任何合适的方式来提供用于使界面板与容器紧密接触的拉伸或压缩力。它们可以包括可以是手动的并且可以是自锁的带螺纹的液压活塞或液压活塞或夹具。

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