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    • 39. 发明申请
    • METHOD AND SYSTEM FOR ORAL PH CHANGE
    • 口腔PH变化的方法和系统
    • WO2016102201A1
    • 2016-06-30
    • PCT/EP2015/079332
    • 2015-12-11
    • KONINKLIJKE PHILIPS N.V.
    • GOTTENBOS, BartVERSCHUEREN, Alwin Rogier Martijn
    • C25B9/00A61Q11/00A61K8/73A61C19/06A46B15/00
    • A46B11/002A46B7/04A46B15/0024A46B2200/1066A46B2200/20A61C1/02A61C15/047A61C17/16A61C19/063A61K8/733A61K8/736C25B9/00
    • Disclosed is a new method, and a system, for increasing the pH of a composition applied on teeth and/or gums. The composition is gelable under the influence of a pH change. The pH change typically is a pH increase in the event of a direct pH-triggered gelation. The pH change typically is a pH decrease in the event of gelation induced by ions, such as calcium ions, released from a pH-sensitive carrier. The device comprises a dispensing unit for the composition, a distal end of which is adapted to apply said substance onto teeth or gums. The device further comprises an electrode system comprising first and second electrodes, the first electrode being adapted to be held against the composition at a location at or near teeth or gums, and the second electrode being adapted to be held against the composition at a location away from teeth or gums, The electrode system is adapted so as to provide an electrical potential difference of 1.5 to 10 Volt between the electrodes.
    • 公开了一种用于增加施用在牙齿和/或牙龈上的组合物的pH的新方法和系统。 该组合物在pH变化的影响下是可凝胶化的。 pH变化通常是在直接pH引发凝胶化的情况下的pH增加。 pH变化通常是在由pH敏感的载体释放的离子(例如钙离子)诱导的凝胶化情况下的pH降低。 该装置包括用于组合物的分配单元,其远端适于将所述物质施加到牙齿或牙龈上。 所述装置还包括包括第一和第二电极的电极系统,所述第一电极适于在牙齿或牙龈处或附近的位置处抵靠所述组合物保持,并且所述第二电极适于在远离的位置处抵靠所述组合物 从牙齿或牙龈,电极系统适于在电极之间提供1.5至10伏电位差。