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21. 发明申请

WO2005112943A1 TOPICAL CROMOLYN FORMULATIONS 审中-公开
标题翻译：主题CROMOLYN制剂
公开(公告)号：WO2005112943A1
公开(公告)日：2005-12-01
申请号：PCT/US2005/017816
申请日：2005-05-19
申请人： EMISPHERE TECHNOLOGIES, INC. , LIU, Puchun , DINH, Steve , ARBIT, Ehud , GOLDBERG, Michael
发明人： LIU, Puchun , DINH, Steve , ARBIT, Ehud , GOLDBERG, Michael
IPC分类号： A61K31/609
CPC分类号： A61K31/609 , A61K9/0014 , A61K9/06 , A61K47/10 , A61K47/183
摘要： The present invention provides a topical composition comprising (a) at least one delivery agent compound and (b) a cromolyn component. Methods of treatment, and methods of preparing the topical composition are also provided.
摘要翻译：本发明提供一种局部组合物，其包含（a）至少一种递送剂化合物和（b）色素组分。还提供了治疗方法和制备局部组合物的方法。

22. 发明申请

WO2005032322A2 HEAT PUMP CLOTHES DRYER 审中-公开
标题翻译：热泵衣物烘干机
公开(公告)号：WO2005032322A2
公开(公告)日：2005-04-14
申请号：PCT/US2004/031624
申请日：2004-09-23
申请人： SELF PROPELLED RESEARCH AND DEVELOPMENT SPECIALISTS, LLC , GOLDBERG, Michael , TRUMAN, James, C. , KNIFFIN, Alexander, B.
发明人： GOLDBERG, Michael , TRUMAN, James, C. , KNIFFIN, Alexander, B.
IPC分类号： A47L
CPC分类号： D06F58/206 , D06F25/00
摘要： A drying apparatus for drying articles such as clothing is provided. The drying apparatus includes a chamber for containing articles to be dried and a system for supplying heated dry air at a first temperature to the chamber. The air supplying system comprises an air flow pathway having an evaporator for removing moisture from air exiting the chamber and for decreasing the temperature of the air to below dew point temperature. The air supply system further has a condenser for increasing the temperature of the air exiting the evaporator to the first temperature. The drying apparatus further has a heat pump system having a refrigerant loop which includes a compressor, the condenser, a TEV valve, and the evaporator.
摘要翻译：提供了用于干燥诸如衣服等物品的干燥设备。干燥装置包括用于容纳待干燥物品的腔室和用于将第一温度的加热干燥空气供应到腔室的系统。空气供应系统包括具有蒸发器的空气流动路径，该蒸发器用于从排出室的空气中除去湿气并将空气的温度降低至低于露点温度。空气供应系统还具有用于将离开蒸发器的空气的温度升高到第一温度的冷凝器。干燥设备还具有热泵系统，该热泵系统具有制冷剂回路，该制冷剂回路包括压缩机，冷凝器，TEV阀和蒸发器。

23. 发明申请

WO03057170A8 ORAL INSULIN THERAPY 审中-公开
标题翻译：口服胰岛素治疗
公开(公告)号：WO03057170A8
公开(公告)日：2004-01-15
申请号：PCT/US0300337
申请日：2003-01-07
申请人： EMISPHERE TECH INC , ARBIT EHUD , ABBAS RICHAT , GOLDBERG MICHAEL , WOOD T COOPER , DINH STEVEN , WONG VIVIEN
发明人： ARBIT EHUD , ABBAS RICHAT , GOLDBERG MICHAEL , WOOD T COOPER , DINH STEVEN , WONG VIVIEN
IPC分类号： G01N33/53 , A61K9/20 , A61K9/48 , A61K38/28 , A61K47/18 , A61P3/10 , A61P9/00 , A61P9/04 , A61P9/10 , A61P13/12 , A61P25/00 , A61P43/00 , G01N33/15 , G01N37/00
CPC分类号： A61K47/18 , A61K9/2013 , A61K9/4858 , A61K38/28 , A61K2300/00
摘要： Pharmaceutical dosage forms for oral administration to a patient for the treatment of diabetes, comprising insulin and a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and that result in a lower incidence of vascular diseases associated with the repeated administration of insulin are disclosed. Also disclosed is a method of attenuating the undesirable incidence of diseases associated with chronic dosing of insulin is provided whereby the oral administration to a patient of insulin along with a suitable delivery agent that facilitates the absorption of insulin from the gastrointestinal tract of the patient in a therapeutically effective amount, for treatment of diabetes.
摘要翻译：用于口服给予患者用于治疗糖尿病的药物剂型，其包含胰岛素和促进胰岛素以治疗有效量转运至血液并且导致与重复施用胰岛素相关的血管疾病的较低发生率的递送剂被披露。还公开了一种减轻与慢性给药胰岛素相关的疾病的不期望的发病率的方法，其中通过口服给予胰岛素患者以及促进从患者的胃肠道吸收胰岛素的合适的递送剂治疗有效量，用于治疗糖尿病。

24. 发明申请

WO03057170A2 ORAL INSULIN THERAPY 审中-公开
标题翻译：口服胰岛素治疗
公开(公告)号：WO03057170A2
公开(公告)日：2003-07-17
申请号：PCT/US0300337
申请日：2003-01-07
申请人： EMISPHERE TECH INC , ARBIT EHUD , ABBAS RICHAT , GOLDBERG MICHAEL , WOOD T COOPER , DINH STEVEN , WONG VIVIEN
发明人： ARBIT EHUD , ABBAS RICHAT , GOLDBERG MICHAEL , WOOD T COOPER , DINH STEVEN , WONG VIVIEN
IPC分类号： G01N33/53 , A61K9/20 , A61K9/48 , A61K38/28 , A61K47/18 , A61P3/10 , A61P9/00 , A61P9/04 , A61P9/10 , A61P13/12 , A61P25/00 , A61P43/00 , G01N33/15 , G01N37/00 , A61K
CPC分类号： A61K47/18 , A61K9/2013 , A61K9/4858 , A61K38/28 , A61K2300/00
摘要： Pharmaceutical dosage forms for oral administration to a patient for the treatment of diabetes, comprising insulin and a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and that result in a lower incidence of vascular diseases associated with the repeated administration of insulin are disclosed. Also disclosed is a method of attenuating the undesirable incidence of diseases associated with chronic dosing of insulin is provided whereby the oral administration to a patient of insulin along with a suitable delivery agent that facilitates the absorption of insulin from the gastrointestinal tract of the patient in a therapeutically effective amount, for treatment of diabetes.
摘要翻译：用于口服给予患者用于治疗糖尿病的药物剂型，其包含胰岛素和促进胰岛素以治疗有效量转运至血液并且导致与重复施用胰岛素相关的血管疾病的较低发生率的递送剂被披露。还公开了一种减轻与慢性给药胰岛素相关的疾病的不期望的发病率的方法，其中通过口服给予胰岛素患者以及促进从患者的胃肠道吸收胰岛素的合适的递送剂治疗有效量，用于治疗糖尿病。

25. 发明申请

WO1997049690A1 A METHOD FOR TREATING MENIERE'S DISEASE 审中-公开
标题翻译：一种治疗男性疾病的方法
公开(公告)号：WO1997049690A1
公开(公告)日：1997-12-31
申请号：PCT/US1997010561
申请日：1997-06-23
申请人： MERCK & CO., INC. , SIEGL, Peter, K., S. , GOLDBERG, Allan, I. , GOLDBERG, Michael, R. , CHANG, Paul, I.
发明人： MERCK & CO., INC.
IPC分类号： C07D243/06
CPC分类号： A61K31/551 , A61K31/00 , A61K31/5513 , C07D243/14 , C07D243/16 , C07D243/20 , C07D243/22 , C07D243/24 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D413/10 , C07D413/12 , C07D487/04 , C07D495/04
摘要： A method for the treatment of Meniere's disease comprising the administration of a medicament which modulates the IKs channel of the ear and thereby reduces endolymph production.
摘要翻译：一种治疗梅尼埃病的方法，包括施用调节耳道的IK通道并从而减少内淋巴产生的药物。

26. 发明申请

WO1986002149A1 HEAT PUMP CLOSED LOOP DRYING 审中-公开
标题翻译：热泵封闭环路干燥
公开(公告)号：WO1986002149A1
公开(公告)日：1986-04-10
申请号：PCT/US1985001972
申请日：1985-10-07
申请人： GOLDBERG, Michael
IPC分类号： F26B11/04
CPC分类号： D06F58/206 , D06F58/02 , F26B21/086 , F26B23/005 , Y02B30/52 , Y02P70/405
摘要： A dryer includes a rotating drum (14) having an inlet (14A) and an outlet (14B). A blower (15) withdraws air from the outlet. A heat pump has an evaporator (17) and condenser (25) interconnected by a compressor (26) and an expansion valve (27). The outlet of the condenser is connected to the inlet of the rotating drum. The water collection tray (21) drains into a sump (23) having a sump pump (24). In a closed loop form the outlet of the rotating drum is coupled to inlet of the evaporator and is thermally coupled to a wet air heat exchanger (16).

27. 发明申请

WO2013036625A1 MODIFICATIONS TO VIBRATING INSTRUMENT FOR REDUCING PAIN DURING SKIN-PUNCTURING PROCEDURES AND METHODS FOR USE OF THE MODIFIED VIBRATING INSTRUMENT 审中-公开
标题翻译：用于在皮肤刺激程序中减少疼痛的振动仪器的修改和使用改性振动仪器的方法
公开(公告)号：WO2013036625A1
公开(公告)日：2013-03-14
申请号：PCT/US2012/053943
申请日：2012-09-06
申请人： BING INNOVATIONS, LLC , GOLDBERG, Steven , GOLDBERG, Michael
发明人： GOLDBERG, Steven , GOLDBERG, Michael
IPC分类号： A61M19/00 , A61H23/00 , A61B19/02
CPC分类号： A61M19/00 , A61B46/10 , A61B90/30 , A61B2017/00902 , A61H23/0254 , A61H2201/0153 , A61H2201/0157 , A61H2201/0188 , A61H2201/0214 , A61H2201/0257 , A61H2201/1685 , A61H2201/1688 , A61M2021/0022 , A61M2205/8206
摘要： The invention provides modifications which improve the function of a vibrating instrument and methods for using the improved vibrating instrument. The vibrating instrument is for reducing pain during skin-puncturing procedures or injections and operates by vibrating tissue surrounding the area of the skin puncture or injection. The modifications include a coolant structure for a vibrating tip of the instrument and a sterile, single-use bag for covering at least a portion of the instrument such that use of the instrument can be prolonged or maximized. The sterile, single-use bag may additionally include a compartment for the coolant structure.
摘要翻译：本发明提供了改善振动仪器的功能的改进以及使用改进的振动仪器的方法。振动仪器用于在皮肤穿刺手术或注射期间减轻疼痛，并通过振动周围皮肤穿刺或注射区域的组织进行操作。这些修改包括用于仪器的振动尖端的冷却剂结构和用于覆盖仪器的至少一部分的无菌的一次性袋，使得可以延长或最大化仪器的使用。无菌的一次性袋可以另外包括用于冷却剂结构的隔间。

28. 发明申请

WO2011115810A3 ISOFORM-SPECIFIC RNAI BASED ON CODON REDUNDANCY/DEGENERACY 审中-公开
标题翻译：基于CODON REDUNDANCY / DEGENERACY的ISOFORM特异性RNAi
公开(公告)号：WO2011115810A3
公开(公告)日：2012-04-19
申请号：PCT/US2011027886
申请日：2011-03-10
申请人： MASSACHUSETTS INST TECHNOLOGY , GOLDBERG MICHAEL SOLOMON
发明人： GOLDBERG MICHAEL SOLOMON
IPC分类号： C12N15/113 , A61K31/7105 , A61K48/00 , A61P35/00
CPC分类号： C12N15/1137 , A61K31/7105 , C12N2310/14
摘要： The invention relates to nucleic acid molecules and compositions for specific post-transcriptional inhibition of PKM2 expression. Methods for specific inhibition of PKM2 expression in a target cell, for example a cancer cell, are also provided.
摘要翻译：本发明涉及用于PKM2表达的特异性转录后抑制的核酸分子和组合物。还提供了在靶细胞例如癌细胞中特异性抑制PKM2表达的方法。

29. 发明申请

WO2010068655A1 NONMETALLIC ULTRA-LOW PERMEABILITY BUTYL TAPE FOR USE AS THE FINAL SEAL IN INSULATED GLASS UNITS 审中-公开
标题翻译：非绝缘超低渗透性胶带用作绝缘玻璃单元中的最终密封
公开(公告)号：WO2010068655A1
公开(公告)日：2010-06-17
申请号：PCT/US2009/067291
申请日：2009-12-09
申请人： SERIOUS MATERIALS, INC. , TINIANOV, Brandon, D. , GOLDBERG, Michael
发明人： TINIANOV, Brandon, D. , GOLDBERG, Michael
IPC分类号： E06B3/00
CPC分类号： E06B3/6621 , B32B3/02 , B32B3/08 , B32B7/12 , B32B25/08 , B32B25/18 , B32B27/08 , B32B27/283 , B32B27/304 , B32B27/40 , B32B2270/00 , B32B2307/304 , B32B2307/7242 , B32B2307/7246 , B32B2581/00 , C09J5/00 , C09J7/245 , C09J123/22 , C09J2421/00 , E06B3/66342 , Y10T428/2878
摘要： The object of the invention is a high performance tape for use in insulated glass units (IGUs) that combines exceptionally low permeability to gases and vapors with extremely low thermal conductivity. Prior art includes low-permeability aluminum-backed tapes as well as low-conductivity polymer-backed tapes, but nothing currently available serves both of these needs with a single product.
摘要翻译：本发明的目的是用于绝缘玻璃单元（IGU）的高性能胶带，其具有极低的气体渗透性和极低导热性的蒸气。现有技术包括低透气性铝背胶带以及低导电性聚合物背胶带，但是目前还没有任何一种使用单一产品来满足这些需求。

30. 发明申请

WO2009099751A1 WASHABLE CHILD CAR SEAT SUBFRAME 审中-公开
标题翻译：可洗的儿童汽车座椅SUBFRAME
公开(公告)号：WO2009099751A1
公开(公告)日：2009-08-13
申请号：PCT/US2009/031422
申请日：2009-01-20
申请人： TIMME, Ruth, G. , GOLDBERG, Michael
发明人： TIMME, Ruth, G. , GOLDBERG, Michael
IPC分类号： B60N2/26 , B60N2/28
CPC分类号： B60N2/28 , B08B3/02
摘要： A child car seat subframe that is easily disassembled into component sections for washing within a residential-sized dishwasher. The car seat subframe can be disassembled by hand, and each individual component is cable of fitting in a residential-sized dishwasher individually and collectively. The component sections are attached by a combination of registration tabs and slots, and held tightly together by fasteners, or attached by a combination of tongue and groove joints. Hanging devices, such as hooks, may be formed on one side of each component section to facilitate hanging on racks in a dishwasher. The car seat subframe back panel and side panels are disassembled into a plurality of segments for easily fitting in a dishwasher.
摘要翻译：一个儿童汽车座椅子框架，容易拆卸成部件，用于在住宅大小的洗碗机内进行清洗。汽车座椅子框架可以手动拆卸，每个单独的部件都是单独和集体地连接在住宅大小的洗碗机中的电缆。组件部分通过对齐片和槽的组合附接，并通过紧固件紧紧地保持在一起，或者通过舌和槽接合的组合来附接。可以在每个部件部分的一侧上形成诸如钩子的悬挂装置，以便于挂在洗碗机中的机架上。汽车座椅副翼后面板和侧板被分解成多个段，以容易地装配在洗碗机中。

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