专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

WO2012120415A1 TETRASUBSTITUTED CYCLOHEXYL COMPOUNDS AS KINASE INHIBITORS 审中-公开
标题翻译：四环素化合物作为激酶抑制剂
公开(公告)号：WO2012120415A1
公开(公告)日：2012-09-13
申请号：PCT/IB2012/050981
申请日：2012-03-01
申请人： NOVARTIS AG , BURGER, Matthew , DING, Yu , HAN, Wooseok , NISHIGUCHI, Gisele , RICO, Alice , SIMMONS, Robert Lowell , SMITH, Aaron R. , TAMEZ, JR., Victoriano , TANNER, Huw , WAN, Lifeng
发明人： BURGER, Matthew , DING, Yu , HAN, Wooseok , NISHIGUCHI, Gisele , RICO, Alice , SIMMONS, Robert Lowell , SMITH, Aaron R. , TAMEZ, JR., Victoriano , TANNER, Huw , WAN, Lifeng
IPC分类号： C07D213/81 , C07D401/14 , C07D405/14 , C07D417/12 , C07D417/14 , A61K31/444 , A61P35/00
CPC分类号： A61K31/4439 , A61K31/444 , A61K31/4745 , A61K31/497 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/5377 , A61K31/664 , A61K31/704 , A61K31/7068 , A61K33/24 , A61K39/395 , A61K45/06 , C07D213/81 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , A61K2300/00
摘要： The present invention provides a compound of formula (I) as further described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula I, and pharmaceutical compositions comprising such compounds.
摘要翻译：本发明提供了本文进一步描述的式（I）化合物及其药学上可接受的盐，对映异构体，旋转异构体，互变异构体或其外消旋体。还提供了使用式I化合物治疗PIM激酶介导的疾病或病症的方法和包含这些化合物的药物组合物。

22. 发明申请

WO2005051988A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSIS 审中-公开
标题翻译：用于治疗系统性红斑狼疮的组合物和方法
公开(公告)号：WO2005051988A2
公开(公告)日：2005-06-09
申请号：PCT/US2004/006460
申请日：2004-03-02
申请人： GENENTECH, INC. , ABBAS, Alexander , BODARY, Sarah , CLARK, Hilary , SCHOENFELD, Jill , WILLIAMS, P. Mickey , WOOD, William I. , WU, Thomas D.
发明人： ABBAS, Alexander , BODARY, Sarah , CLARK, Hilary , SCHOENFELD, Jill , WILLIAMS, P. Mickey , WOOD, William I. , WU, Thomas D.
IPC分类号： C07K14/435
CPC分类号： C07K14/435 , A61K38/00
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases
摘要翻译：本发明涉及含有新蛋白质的组合物以及使用这些组合物诊断和治疗免疫相关疾病的方法

23. 发明申请

WO2004039394A1 NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES 审中-公开
标题翻译：新型组合物和治疗免疫相关疾病的方法
公开(公告)号：WO2004039394A1
公开(公告)日：2004-05-13
申请号：PCT/US2003/005335
申请日：2003-02-19
申请人： GENENTECH, INC.
发明人： CLARK, Hilary , EATON, Dan L. , GURNEY, Austin L. , WRANIK, Bernd
IPC分类号： A61K38/17
CPC分类号： C07K14/705 , A61K38/00 , C07K16/28 , C07K2319/00 , G01N33/5011 , G01N33/57407 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/24 , G01N2800/245
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译：本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。

24. 发明申请

WO2004037690A1 BELT CONVEYOR WITH A SUPPORTING PLATFORM FORMED FROM A SINGLE SHEET OF METAL 审中-公开
标题翻译：带式输送机，带有从金属单片形成的支撑平台
公开(公告)号：WO2004037690A1
公开(公告)日：2004-05-06
申请号：PCT/GB2003/004572
申请日：2003-10-24
申请人： INNOVEYTION LIMITED , SPOORS, Simon
发明人： SPOORS, Simon
IPC分类号： B65G21/02
CPC分类号： B65G21/02
摘要： A conveyor, primarily but not exclusively for use in the food industry, in which a conveyor belt (19) is supported on a belt platform (11) for movement relative thereto, and the belt platform (11) is formed as a unitary component from a single sheet metal blank. Preferably the conveyor includes a support leg structure (12, 13) and that supporting leg structure is also formed as a unitary component from a single metal blank. Most preferably the belt platform and the supporting leg structure are formed as a unitary component from a single metal blank.
摘要翻译：主要但不仅限于在食品工业中使用的输送机，其中输送带（19）被支撑在带平台（11）上以便相对于其移动，并且带平台（11）形成为从一块金属板坯。优选地，输送机包括支撑腿结构（12,13），并且支撑腿结构也由单一金属坯料形成为整体部件。最优选地，带平台和支撑腿结构从单个金属坯料形成为整体部件。

25. 发明申请

WO2004013004A1 SELF-ERECTING BOX STRUCTURES 审中-公开
标题翻译：自拍盒结构
公开(公告)号：WO2004013004A1
公开(公告)日：2004-02-12
申请号：PCT/GB2003/003378
申请日：2003-08-01
申请人： PLAYPOD LIMITED , RAMPLIN, Denis
发明人： RAMPLIN, Denis
IPC分类号： B65D5/36
CPC分类号： A01K1/0125 , A01K1/033 , A63H33/044 , B65D5/3628 , B65D81/368 , B65D85/50
摘要： A self-erecting box structure which, in an erect condition, comprises first, second, third and fourth walls (11, 12, 13, 14), first, second, third, and fourth hinge connections (15, 16, 17, 18) interconnecting respectively the adjacent edges of the four walls (11, 12, 13, 14), the four hinge connections having axes of hinging movement generally coincident with the adjacent longitudinal edges of their respective walls, said second and fourth walls (12, 14) each being defined by first and second portions (12a, 12b; 14a, 14b) interconnected by respective fifth and sixth hinge connections (29, 31), the structure being capable of being collapsed said structure further including resilient means (35) stressed by collapsing movement of the box structure from an erect condition to a collapsed condition and, abutment means (19) against which said second and fourth walls (12, 14)abut in the erect condition of the box structure.
摘要翻译：一种自立式箱体结构，其直立状态包括第一，第二，第三和第四壁（11,12,13,14），第一，第二，第三和第四铰链连接件（15,16,17,18）分别互连四个壁（11,12,13,14）的相邻边缘，四个铰链连接件具有铰链运动的轴线，大体上与其各自的壁的相邻纵向边缘重合，所述第二和第四壁（12,14）），每个由相应的第五和第六铰链连接件（29,31）互连的第一和第二部分（12a，12b; 14a，14b）限定，所述结构能够被塌缩，所述结构还包括弹性装置（35）盒结构从直立状态到折叠状态的塌缩运动;以及邻接装置（19），所述第二和第四壁（12,14）在盒结构的直立状态下与其抵接。

26. 发明申请

WO2004000469A1 HOSES 审中-公开
公开(公告)号：WO2004000469A1
公开(公告)日：2003-12-31
申请号：PCT/GB2003/002636
申请日：2003-06-19
申请人： ITW LIMITED , WOOD, Nigel, Charles
发明人： WOOD, Nigel, Charles
IPC分类号： B05B7/24
CPC分类号： B05B7/2489
摘要： A hose structure for a paint spraying system, comprising a paint supply hose (18) extending within a paint return hose (19), and having an outer diameter which is less than the inner diameter of the paint return hose (19) so as to provide a clearance between the exterior of the supply hose (18) and the interior of the return hose (19) to provide a return path (24), and, said paint return hose (19) extending within an air supply hose (21) and having an outer diameter which is less than the inner diameter of the air supply hose (21) so as to provide a clearance (25) between the exterior of the paint return hose (19) and the interior of the air supply hose (21) through which an air supply can flow.
摘要翻译：一种用于喷漆系统的软管结构，包括在涂料返回软管（19）内延伸的涂料供应软管（18），其外径小于涂料返回软管（19）的内径，从而在供应软管（18）的外部和返回软管（19）的内部之间提供间隙，以提供返回路径（24），并且在空气供应软管（21）内延伸的所述涂料返回软管（19）并且具有小于所述供气软管（21）的内径的外径，以便在所述涂料返回软管（19）的外部和所述空气供应软管（21）的内部之间提供间隙（25）），空气供应可以通过其流动。

27. 发明申请

WO2003076569A3 NOVEL POLYPEPTIDES HAVING SEQUENCE SIMILARITY TO GDNFR AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开
公开(公告)号：WO2003076569A3
公开(公告)日：2003-09-18
申请号：PCT/US2003/005169
申请日：2003-02-18
申请人： GENENTECH, INC.
发明人： GRIMALDI, Christopher J. , SESHAGIRI, Somasekar , STINSON, Jeremy , WOOD, William I. , ZHANG, Zemin
IPC分类号： C07H21/04
摘要： The present invention is directed to novel polypeptides having sequence similarity to GDNFR and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

28. 发明申请

WO2003055440A3 COMPOSITIONS AND METHODS FOR THE TREATEMENT OF IMMUNE RELATED DISEASES 审中-公开
公开(公告)号：WO2003055440A3
公开(公告)日：2003-07-10
申请号：PCT/US2002/024252
申请日：2002-07-30
申请人： GENENTECH, INC.
发明人： GREWAL, Iqbal , GURNEY, Austin, L. , VALDEZ, Patricia A.
IPC分类号： C07K1/00
摘要： The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases.

29. 发明申请

WO2003034984A9 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF INFLAMMATORY BOWEL DISORDERS 审中-公开
公开(公告)号：WO2003034984A9
公开(公告)日：2003-05-01
申请号：PCT/US2002/033070
申请日：2002-10-15
申请人： GENENTECH, INC. , GODDARD, Audrey , GURNEY, Austin L.
发明人： GODDARD, Audrey , GURNEY, Austin L.
IPC分类号： C12N15/00 , C07H21/04 , C07K14/00

30. 发明申请

WO2003034984A2 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF INFLAMMATORY BOWEL DISORDERS 审中-公开
标题翻译：用于诊断和治疗炎症性阴道病的组合物和方法
公开(公告)号：WO2003034984A2
公开(公告)日：2003-05-01
申请号：PCT/US2002/033070
申请日：2002-10-15
申请人： GENENTECH, INC. , GODDARD, Audrey , GURNEY, Austin L.
发明人： GODDARD, Audrey , GURNEY, Austin L.
IPC分类号： A61K
CPC分类号： C07K16/28 , A61K47/6843 , A61K51/1018 , A61K51/1027 , C07K14/4713 , C07K14/705 , C12Q1/6876 , C12Q1/6883 , C12Q2600/136 , C12Q2600/158 , G01N33/53 , G01N2800/065
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of inflammatory bowel diseases in mammals and to methods of using those compositions of matter for the same.
摘要翻译：本发明涉及可用于诊断和治疗哺乳动物炎症性肠病的物质组合物，以及使用该物质组合物的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式