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11. 发明申请

WO2006059123A8 MASS SPECTROMETER 审中-公开
标题翻译：质谱分析仪
公开(公告)号：WO2006059123A8
公开(公告)日：2007-04-12
申请号：PCT/GB2005004627
申请日：2005-12-02
申请人： MICROMASS LTD , BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK
发明人： BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK
IPC分类号： H01J49/42 , H01J49/40
CPC分类号： H01J49/065
摘要： An ion guide (7a) is disclosed comprising one or more layers of intermediate planar, plate or mesh electrodes (2). A first array of first electrodes (8a-8e) is provided on an upper surface and a second array of second electrodes (9a-9e) is arranged on a lower surface. An ion guiding region is formed within the ion guide (7a). One or more transient DC voltages or potentials are preferably applied to the first and second array of second electrodes (8a-8e, 9a-9e) in order to urge, propel, force or accelerate ions through or along the ion guide (7a).
摘要翻译：公开了一种离子导向器（7a），其包括一个或多个中间平面，平板或网状电极（2）的层。第一电极阵列（8a-8e）设置在上表面上，第二电极阵列（9a-9e）设置在下表面上。在离子引导件（7a）内形成离子引导区域。优选将一个或多个瞬态DC电压或电势施加到第二电极（8a-8e，9a-9e）的第一阵列和第二阵列以促使，推动，迫使或加速离子通过或沿着离子导向器（7a）。

12. 发明申请

WO2008071967A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008071967A3
公开(公告)日：2009-01-08
申请号：PCT/GB2007004774
申请日：2007-12-12
申请人： MICROMASS LTD , GILES KEVIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
发明人： GILES KEVIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
IPC分类号： H01J49/40 , H01J49/42
CPC分类号： G01N27/622 , G01N27/624 , H01J49/062 , H01J49/4235
摘要： A mass spectrometer is disclosed comprising a device (2) which is operable in a first mode of operation to separate ions temporally according to their ion mobility by applying a continuous axial electric field. The device (2) is also operable in a second mode of operation wherein ions are separated temporally according to the their mass to charge ratio by pulsing an applied axial electric field ON and OFF.
摘要翻译：公开了一种质谱仪，其包括可在第一操作模式中操作的装置（2），其通过施加连续的轴向电场根据其离子迁移率暂时分离离子。装置（2）还可在第二操作模式中操作，其中通过脉冲施加的轴向电场ON和OFF，离子根据其质荷比逐时分离。

13. 发明申请

WO2006059123A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006059123A3
公开(公告)日：2007-02-22
申请号：PCT/GB2005004627
申请日：2005-12-02
申请人： MICROMASS LTD , BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK
发明人： BATEMAN ROBERT HAROLD , GILES KEVIN , PRINGLE STEVEN DEREK
IPC分类号： H01J49/42 , H01J49/40
CPC分类号： H01J49/065
摘要： An ion guide (7a) is disclosed comprising one or more layers of intermediate planar, plate or mesh electrodes (2). A first array of first electrodes (8a-8e) is provided on an upper surface and a second array of second electrodes (9a-9e) is arranged on a lower surface. An ion guiding region is formed within the ion guide (7a). One or more transient DC voltages or potentials are preferably applied to the first and second array of second electrodes (8a-8e, 9a-9e) in order to urge, propel, force or accelerate ions through or along the ion guide (7a).
摘要翻译：公开了一种离子导向器（7a），其包括一层或多层中间平面，板状或网状电极（2）。第一电极阵列（8a-8e）设置在上表面上，第二电极阵列（9a-9e）布置在下表面上。离子引导区域形成在离子导向器（7a）内。优选地将一个或多个瞬态DC电压或电位施加到第一和第二第二电极阵列（8a-8e，9a-9e），以促使，推动，强迫或加速离子通过或沿着离子导向器（7a）。

14. 发明申请

WO2006075189A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006075189A3
公开(公告)日：2007-05-18
申请号：PCT/GB2006000155
申请日：2006-01-17
申请人： MICROMASS LTD , GILES KEVIN , GREEN MARTIN , WILDGOOSE JASON LEE
发明人： GILES KEVIN , GREEN MARTIN , WILDGOOSE JASON LEE
IPC分类号： H01J49/04 , H01J49/42
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap 1 is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap 1 by the application of an AC or RF voltage to the electrodes. Ions are trapped within an axial quadratic potential well which is oscillated or modulated axially so as to cause ions to be ejected from the ion guide or ion trap 1 in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱1，其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子限制在离子导向器或离子阱1的径向内。离子被捕获在轴向二次势阱内，其轴向振荡或调制，以使离子以基本上非共振的方式从离子导向器或离子阱1喷出。

15. 发明申请

WO2013027054A2 ION TRAP WITH SPATIALLY EXTENDED ION TRAPPING REGION 审中-公开
标题翻译：离子阱与空间扩展的离子俘获区域
公开(公告)号：WO2013027054A2
公开(公告)日：2013-02-28
申请号：PCT/GB2012052053
申请日：2012-08-22
申请人： MICROMASS LTD , GILES KEVIN , GREEN MARTIN RAYMOND , KENNY DANIEL JAMES , LANGRIDGE DAVID J , WILDGOOSE JASON LEE
发明人： GILES KEVIN , GREEN MARTIN RAYMOND , KENNY DANIEL JAMES , LANGRIDGE DAVID J , WILDGOOSE JASON LEE
IPC分类号： H01J49/42
CPC分类号： H01J49/424 , H01J49/421 , H01J49/422 , H01J49/4285
摘要： A mass or mass to charge ratio selective ion trap is disclosed having an increased charge storage capacity. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC voltage and/or an RF voltage acts to confine ions in a second (x) direction within the ion trap. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. Ions are excited in the third (z) direction and are caused to be mass or mass to charge ratio selectively ejected in the third (z) direction.
摘要翻译：公开的具有增加的电荷存储容量的质量或质荷比选择离子阱。 RF电压用于在离子阱内的第一（y）方向上限制离子。直流电压和/或RF电压用于在离子阱内的第二（x）方向上限制离子。二次直流势阱用于在离子阱内的第三（z）方向上限制离子。离子在第三（z）方向上被激发，并且导致质量或质荷比选择性地在第三（z）方向上喷射。

16. 发明申请

WO2006075182A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006075182A2
公开(公告)日：2006-07-20
申请号：PCT/GB2006000138
申请日：2006-01-17
申请人： MICROMASS LTD , GILES KEVIN , GREEN MARTIN , WILDGOOSE JASON LEE
发明人： GILES KEVIN , GREEN MARTIN , WILDGOOSE JASON LEE
IPC分类号： H01J49/04 , H01J49/40
CPC分类号： H01J49/4235 , H01J49/4275
摘要： An ion guide or ion trap (1) is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap (1) by the application of an AC or RF voltage to the electrodes. A static potential well is maintained along at least a portion of the axial length of the ion guide or ion trap (1). A time varying homogeneous electric field is applied along at least a portion of the axial length of the ion guide or ion trap (1). The combination of the static axial potential well and the time varying axial homogeneous electric field causes ions to be ejected from the ion guide or ion trap (1) in a substantially non-resonant manner.
摘要翻译：公开了一种离子导向器或离子阱（1），其包括分段线性离子导向器或离子阱。通过向电极施加AC或RF电压，离子在径向上被限制在离子导向器或离子阱（1）内。沿离子导向器或离子阱（1）的轴向长度的至少一部分保持静电势阱。沿离子导向器或离子阱（1）的轴向长度的至少一部分施加时变均匀电场。静态轴向势阱和随时间变化的轴向均匀电场的组合导致离子以基本上非共振的方式从离子导向器或离子阱（1）喷出。

17. 发明申请

WO2006061593A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006061593A3
公开(公告)日：2007-06-14
申请号：PCT/GB2005004672
申请日：2005-12-07
申请人： MICROMASS LTD , BATEMAN ROBERT HAROLD , GILES KEVIN
发明人： BATEMAN ROBERT HAROLD , GILES KEVIN
IPC分类号： H01J49/04 , G01N27/64 , H01J49/40
CPC分类号： H01J49/0045 , G01N27/622 , H01J49/004 , H01J49/022 , H01J49/062
摘要： A mass spectrometer is disclosed comprising a first quadrupole rod set mass filter (7), a collision cell (8), an ion mobility spectrometer or separator, an ion guide or collision cell (13) arranged downstream of the ion mobility spectrometer or separator, a second quadrupole rod set mass filter (16) and an ion detector (15).
摘要翻译：公开了一种质谱仪，其包括第一四极杆组质量过滤器（7），碰撞池（8），离子迁移谱仪或分离器，位于离子迁移谱仪或分离器下游的离子导向器或碰撞池（13）第二四极杆组质量过滤器（16）和离子检测器（15）。

18. 发明申请

WO2009037483A3 ION GUIDING DEVICE 审中-公开
标题翻译：离子导向装置
公开(公告)号：WO2009037483A3
公开(公告)日：2009-11-19
申请号：PCT/GB2008003198
申请日：2008-09-22
申请人： MICROMASS LTD , GILES KEVIN
发明人： GILES KEVIN
IPC分类号： H01J49/06
CPC分类号： H01J49/065 , H01J49/062 , H01J49/26
摘要： An ion guiding device is disclosed comprising a first ion guide (7) which is conjoined with a second ion guide (8). Ions are urged across a radial pseudo-potential barrier which separates the two guiding regions by a DC potential gradient. Ions may be transferred from an ion guide which has a relatively large cross- sectional profile to an ion guide which has a relatively small cross-sectional profile in order to improve the subsequent ion confinement of the ions.
摘要翻译：公开了一种离子引导装置，其包括与第二离子引导件（8）结合的第一离子引导件（7）。离子通过将两个引导区域分离直流电势梯度的径向伪电势势垒。离子可以从具有相对较大横截面轮廓的离子导向器转移到具有相对较小横截面轮廓的离子导向器，以便改进离子的后续离子限制。

19. 发明申请

WO2013005061A3 PHOTO-DISSOCIATION OF PROTEINS AND PEPTIDES IN A MASS SPECTROMETER 审中-公开
标题翻译：蛋白质和蛋白质在质谱仪中的照片分离
公开(公告)号：WO2013005061A3
公开(公告)日：2013-06-27
申请号：PCT/GB2012051610
申请日：2012-07-06
申请人： MICROMASS LTD , BROWN JEFFERY MARK , GILES KEVIN , KENNY DANIEL JAMES , MURRAY PAUL , RICHARDSON KEITH
发明人： BROWN JEFFERY MARK , GILES KEVIN , KENNY DANIEL JAMES , MURRAY PAUL , RICHARDSON KEITH
IPC分类号： H01J49/00
CPC分类号： H01J49/0059 , G01N27/624 , H01J49/0027 , H01J49/0031 , H01J49/062 , H01J49/10 , H01J49/26 , H01J49/40 , H01J49/422 , H01J49/4245
摘要： A method of mass spectrometry is disclosed comprising directing first photons from a laser onto ions located within a 2D or linear ion guide or ion trap. The frequency of the first photons is scanned and first photons and/or second photons emitted by the ions are detected. The ions are then mass analysed using a Time of Flight mass analyser.
摘要翻译：公开了一种质谱法，其包括将来自激光器的第一光子引导到位于2D或线性离子导向器或离子阱内的离子上。扫描第一光子的频率，并检测由离子发射的第一光子和/或第二光子。然后使用飞行时间质量分析仪对离子进行质量分析。

20. 发明申请

WO2008102163A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008102163A3
公开(公告)日：2009-06-25
申请号：PCT/GB2008000629
申请日：2008-02-25
申请人： MICROMASS LTD , CAMPUZANO IAIN , GILES KEVIN , HUGHES CHRIS
发明人： CAMPUZANO IAIN , GILES KEVIN , HUGHES CHRIS
IPC分类号： H01J49/04
CPC分类号： H01J49/0481 , H01J49/0431 , H01J49/067
摘要： A mass spectrometer is disclosed comprising a sampling cone (3) and a cone-gas cone (4) wherein, in use, sulphur hexa fluoride ('SF6') is supplied as a cone gas (5) to the annulus between the cone-gas cone (4) and the sampling cone (3) in order to improve the transmission of high molecular mass ions passing through the sampling cone (3) into and through subsequent stages of the mass spectrometer.
摘要翻译：公开了一种质谱仪，其包括采样锥体（3）和锥形气体锥体（4），其中在使用中将六氟化硫（“SF 6”）作为锥形气体（5）供应到圆锥体气体锥体（4）和采样锥体（3），以改善通过采样锥体（3）进入质谱仪后续阶段的高分子量离子的透射。

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