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11. 发明申请

WO2012023070A3 DEHYDRATION SENSORS HAVING BUFFERED INKS 审中-公开
标题翻译：具有缓冲油墨的脱水传感器
公开(公告)号：WO2012023070A3
公开(公告)日：2012-06-07
申请号：PCT/IB2011053311
申请日：2011-07-25
申请人： KIMBERLY CLARK CO , WEI NING , SONG XUEDONG , PHILLIPS RONNIE L
发明人： WEI NING , SONG XUEDONG , PHILLIPS RONNIE L
IPC分类号： G01N33/52 , A61L15/56 , G01N21/80
CPC分类号： G01N21/80 , A61F13/42 , G01N21/81 , G01N2021/7759
摘要： A dehydration sensor having a stable, printable, buffered-ink composition that enables one to miniaturize the detection zone and permits both buffer and indicator dye to be applied in the same area of a detection zone, without need for a conventional, large buffer pad region.
摘要翻译：一种具有稳定的可印刷缓冲油墨组合物的脱水传感器，其使得能够使检测区域小型化并且允许将缓冲液和指示剂染料施加在检测区域的相同区域中，而不需要常规的大的缓冲垫区域。

12. 发明申请

WO2011073809A3 WATER-TRIGGERED COLORING OR COLOR CHANGING INDICATOR 审中-公开
标题翻译：水刺颜色或颜色变化指示
公开(公告)号：WO2011073809A3
公开(公告)日：2011-11-24
申请号：PCT/IB2010055098
申请日：2010-11-09
申请人： KIMBERLY CLARK CO , GIL JUNMO , SONG XUEDONG
发明人： GIL JUNMO , SONG XUEDONG
IPC分类号： C09D11/00 , A61L15/56 , B41M5/00 , C09D11/10 , G01N21/78
CPC分类号： A61F13/42 , A61L15/56 , C08K5/0041 , Y10T428/249953 , Y10T428/31504 , Y10T428/31938 , Y10T428/31971
摘要： An ink formulation that includes a reversible color-developing complex formed from a dye precursor molecule having a triarylmethane derivative structure modified with a leaving-group (L) that disassociates from said dye precuror when subjected to environmental conditions of either a neutral or acidic pH value is described. Also the invention pertains to diagnostic indicators or absorbent personal care products that have the ink formulation applied to at least a part of the product.
摘要翻译：一种油墨制剂，其包含由具有在离去基团（L）修饰的三芳基甲烷衍生物结构的染料前体分子形成的可逆显色复合物，其在经受中性或酸性pH值的环境条件时与所述染料前体分离被描述。本发明还涉及具有将油墨制剂应用于产品的至少一部分的诊断指示剂或吸收性个人护理产品。

13. 发明申请

WO2011007285A3 MULTIPLE COMPONENT MATERIALS HAVING A COLOR-CHANGING COMPOSITION 审中-公开
标题翻译：具有颜色变化组成的多种组分材料
公开(公告)号：WO2011007285A3
公开(公告)日：2011-06-30
申请号：PCT/IB2010053007
申请日：2010-06-30
申请人： KIMBERLY CLARK CO , GIL JUNMO , YANG SEUNGRIM , SONG XUEDONG
发明人： GIL JUNMO , YANG SEUNGRIM , SONG XUEDONG
IPC分类号： B32B27/20 , B32B27/08 , B32B27/12 , C08J5/18
CPC分类号： A61L15/56 , A61L15/22 , C08J7/047 , Y10T428/24802 , Y10T428/254 , Y10T428/31587 , Y10T428/31757 , Y10T428/31938 , Y10T442/674
摘要： The present invention relates to a multiple-component material including a substrate and a film layer on the substrate. The film layer includes a color- changing composition to indicate a change in condition, such as a change in pH. The color-changing composition includes a water-insoluble, film-forming polymer, a pH adjuster and a water-insoluble particle. The water-insoluble particle has a charged colorant immobilized on it.
摘要翻译：本发明涉及在基板上包括基板和薄膜层的多组分材料。膜层包括变色组合物，以指示条件的变化，例如pH的变化。变色组合物包括水不溶性，成膜聚合物，pH调节剂和水不溶性颗粒。水不溶性颗粒具有固定在其上的带电着色剂。

14. 发明申请

WO2011073807A2 AQUEOUS-TRIGGERED COLOR-APPEARING INKS 审中-公开
标题翻译：水性引发的颜色 - 出现的油墨
公开(公告)号：WO2011073807A2
公开(公告)日：2011-06-23
申请号：PCT/IB2010055096
申请日：2010-11-09
申请人： KIMBERLY CLARK CO , SONG XUEDONG
发明人： SONG XUEDONG
IPC分类号： C09D11/00 , A61L15/56 , B41M5/00 , C09D11/10 , G01N21/78
CPC分类号： A61L15/225 , A61F13/42 , A61L15/56 , C09B67/0077 , C09B67/0078
摘要： The invention describes a color-developing composition that contains at least four major components: (1) a leuco dye or a combination of leuco dyes, (2) an electron- withdrawing color-developer agent or a combination of color-developers that can form colored complexes with the leuco dyes, (3) a separator or combination of separators that when present in sufficient amounts, can prevent the formation of the colored complexes between the color-developer and leuco dyes, all contained within (4) an encapsulation matrix that includes at least one film-forming and one aqueous-insoluble polymer. All of the foregoing components are dissolved together in a volatile organic solvent medium to form a homogeneous solution that can be applied as an ink on substrates, which can be incorporated as part of absorbent articles or personal care products.
摘要翻译：本发明描述了一种彩色显影组合物，其含有至少四种主要组分：（1）无色染料或无色染料的组合，（2）吸电子彩色显影剂或彩色显影剂的组合，其可形成（3）分离器或分离器的组合，当其以足够的量存在时，可防止所有包含在（4）包封基质内的显色剂和无色染料之间着色复合物的形成，所述包封基质为包括至少一种成膜和一种水不溶性聚合物。所有上述组分一起溶解在挥发性有机溶剂介质中以形成均匀溶液，其可以作为油墨施用在基底上，其可以作为吸收制品或个人护理产品的一部分引入。

15. 发明申请

WO2010049829A8 ABSORBENT ARTICLES WITH IMPENDING LEAKAGE SENSORS 审中-公开
标题翻译：吸收泄漏传感器的文章
公开(公告)号：WO2010049829A8
公开(公告)日：2011-05-05
申请号：PCT/IB2009053880
申请日：2009-09-04
申请人： KIMBERLY CLARK CO , SONG XUEDONG , RANGANATHAN SRIDHAR
发明人： SONG XUEDONG , RANGANATHAN SRIDHAR
IPC分类号： A61F13/42 , A61F13/15
CPC分类号： A61F13/42
摘要： In accordance with one embodiment of the present disclosure an absorbent article capable of indicating the presence or absence of urine as well as impending leakage of urine is disclosed. The absorbent article includes a substantially liquid impermeable layer, a liquid permeable layer, and an absorbent core positioned between the substantially liquid impermeable layer and the liquid permeable layer. A plurality of sensors are integrated into the article across the width of the article and positioned such that the sensors are in fluid communication with urine when provided by a wearer of the article. At least one of the sensors comprises a pH indicator. At least one of the sensors is capable of indicating the presence or absence of urine and at least one of the sensors is capable of indicating impending leakage of urine from the article.
摘要翻译：根据本公开的一个实施例，公开了能够指示尿液的存在或不存在以及尿液即将泄漏的吸收制品。吸收制品包括基本上液体不可渗透层，液体可渗透层和位于基本上液体不可渗透层和液体可渗透层之间的吸收芯。多个传感器跨越制品的宽度集成到制品中，并且定位成使得当由制品的穿着者提供时，传感器与尿流体连通。至少一个传感器包括pH指示器。传感器中的至少一个能够指示尿液的存在或不存在，并且至少一个传感器能够指示来自制品的尿液即将泄漏。

16. 发明申请

WO2010070468A3 LATERAL-FLOW POROUS MEMBRANE ASSAY WITH FLOW RATE CONTROL 审中-公开
标题翻译：具有流量控制的侧向流动多孔膜测定
公开(公告)号：WO2010070468A3
公开(公告)日：2010-08-26
申请号：PCT/IB2009054614
申请日：2009-10-20
申请人： KIMBERLY CLARK CO , SONG XUEDONG , FEASTER SHAWN R , TAKEUCHI JAMES M , YANG KAIYUAN
发明人： SONG XUEDONG , FEASTER SHAWN R , TAKEUCHI JAMES M , YANG KAIYUAN
IPC分类号： G01N9/36
CPC分类号： A61F13/42 , G01N33/54386 , G01N33/558 , Y10T428/18
摘要： Various modifications to a porous substrate, such as employed in lateral flow assay devices, to regulate or modify the flow rate and/or flow path pattern of a fluid through the porous substrate is described. The lateral flow assay device has a porous substrate matrix in fluid communication with a flow-rate control zone having a number of flow-rate control devices arranged as features in or on a substrate surface or laminates thereof in a body. The flow-rate control devices may include: a density gradient, porosity gradient, ion affinity gradient, micro-channels, and combinations thereof.
摘要翻译：描述了多孔基底的各种修改，例如用于横向流动测定装置，以调节或改变通过多孔基底的流体的流速和/或流动路径图案。侧流测定装置具有与流量控制区流体连通的多孔基质基质，该流速控制区具有多个流速控制装置，该流量控制装置作为特征置于基体表面中或基体表面上或层叠体上。流量控制装置可以包括：密度梯度，孔隙度梯度，离子亲和梯度，微通道及其组合。

17. 发明申请

WO2012077004A3 WETNESS SENSOR FOR USE IN AN ABSORBENT ARTICLE 审中-公开
标题翻译：用于吸收性物品的湿度传感器
公开(公告)号：WO2012077004A3
公开(公告)日：2012-08-23
申请号：PCT/IB2011054837
申请日：2011-10-31
申请人： KIMBERLY CLARK CO , WEI NING , SONG XUEDONG
发明人： WEI NING , SONG XUEDONG
IPC分类号： A61F13/42 , A61F13/511 , A61F13/514 , A61F13/53 , A61L15/56
CPC分类号： A61L15/56 , A61F13/42 , A61F2013/422
摘要： A wetness sensor for an absorbent article that is formed from an ink is provided. The ink includes a proton-accepting chromogen and a proton-donating agent (or color developer). Prior to use, the ink is generally dry and in a protonated form so that it has a visible color. However, upon contact with bodily fluids {e.g., urine, fecal matter, mucus, menses, vaginal fluid, etc.), water in the fluid can lead to deprotonation of the chromogen, thereby resulting in a shift of the absorption maxima of the chromogen towards either the red {"bathochromic shift") or blue end of the spectrum ("hypsochromic shift"). To increase the rate of the color change during use, the present inventors have discovered that a specific type of proton-donating agent may be employed. More particularly, the proton- donating agent is an aliphatic carboxylic acid that is highly soluble in the bodily fluid (e.g., urine), and therefore results in a color change that is very rapid and may be detected within a relatively short period of time. The extent of the color change is also generally sufficient to provide a "real-time" indication of wetness on the absorbent article.
摘要翻译：提供一种由油墨形成的吸收性物品的湿度传感器。墨水包括质子接受发色剂和质子给予剂（或彩色显影剂）。在使用之前，油墨通常是干燥的并且是质子化的，因此它具有可见的颜色。但是，在与体液（例如尿液，粪便物质，粘液，月经，阴道液体等）接触时，流体中的水可能导致发色团脱质子化，从而导致色原体的吸收最大值朝向红色（“红移”）或光谱的蓝色结束（“蓝移”）。为了提高使用过程中颜色变化的速率，本发明人发现可以使用特定类型的供质子剂。更具体地说，质子给药剂是高度可溶于体液（例如尿液）中的脂肪族羧酸，因此导致颜色变化非常迅速并且可以在相对短的时间内检测到。颜色变化的程度通常也足以提供吸湿用品上“湿度”的“实时”指示。

18. 发明申请

WO2012077007A2 COLOR-CHANGING COMPOSITION 审中-公开
标题翻译：颜色变化组成
公开(公告)号：WO2012077007A2
公开(公告)日：2012-06-14
申请号：PCT/IB2011055002
申请日：2011-11-09
申请人： KIMBERLY CLARK CO , SONG XUEDONG
发明人： SONG XUEDONG
IPC分类号： C09K9/00 , A47K7/00 , A61F13/15 , C09K3/00
CPC分类号： G01N21/78 , A61F13/51496 , A61F2013/422 , A61F2013/8497 , A61L15/56 , G01N21/81 , G01N31/22 , G01N31/222
摘要： The present invention relates to a color-changing composition and a multiple- component material including a substrate and a printed layer on the substrate. The printed layer includes a color-changing composition to indicate a change in condition, such as a change in wetness. The color-changing composition includes a matrix-forming component, a leuco dye, a Lewis Acid, a neutral surfactant and an organic solvent.
摘要翻译：本发明涉及一种变色组合物和多组分材料，其包括在基底上的基底和印刷层。印刷层包括变色组合物，以指示条件的变化，例如湿度变化。变色组合物包括基质形成组分，无色染料，路易斯酸，中性表面活性剂和有机溶剂。

19. 发明申请

WO2011080626A3 ANTI-VIRAL TISSUE PRODUCT WITH VISUAL EFFICACY INDICATOR 审中-公开
标题翻译：具有视觉效能指示剂的抗病毒组织产品
公开(公告)号：WO2011080626A3
公开(公告)日：2011-12-01
申请号：PCT/IB2010055553
申请日：2010-12-02
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , MARTIN STEPHANIE M , PHILLIPS RONNIE L , SONG XUEDONG
发明人： MACDONALD JOHN GAVIN , MARTIN STEPHANIE M , PHILLIPS RONNIE L , SONG XUEDONG
IPC分类号： A47K10/16 , D21H21/28 , D21H21/36 , D21H23/24 , G01N31/22 , G01N33/52
CPC分类号： A61K31/194 , A61K31/00
摘要： Anti-viral tissues are provided with a pH indicator which can communicate to a tissue user by means of visual indicia, via color changes, that the tissue has active ingredients. Furthermore, the pH indicators can be used to illustrate neutralization of the pH of infected nasal discharge, which has a higher pH than healthy nasal discharge, giving the user a reason to believe that the product is working to deactivate virus.
摘要翻译：抗病毒组织具有pH指示剂，该指示剂可以通过视觉标记通过颜色变化与组织使用者通信，该组织具有活性成分。此外，pH指示剂可用于说明中和感染的鼻腔排出物的pH，其具有比健康鼻腔排出物更高的pH值，从而使用户有理由相信该产品正在努力使病毒失活。

20. 发明申请

WO2010131127A3 ABSORBENT ARTICLES CAPABLE OF INDICATING THE PRESENCE OF URINARY TRACT INFECTIONS 审中-公开
标题翻译：能够表明尿道感染的存在的吸收性文章
公开(公告)号：WO2010131127A3
公开(公告)日：2011-03-24
申请号：PCT/IB2010051511
申请日：2010-04-07
申请人： KIMBERLY CLARK CO , SONG XUEDONG
发明人： SONG XUEDONG
IPC分类号： G01N33/52 , G01N30/02 , G01N33/493 , G01N33/58
CPC分类号： G01N31/227 , A61B10/007 , A61B2010/0006 , B01L3/5023 , B01L2300/0825 , G01N33/84
摘要： In accordance with one embodiment of the present disclosure, a diagnostic test kit for detecting the presence or absence of nitrites within a test sample is disclosed. The test kit comprises an aromatic primary amine that is capable of reacting with a nitrite to form a diazonium ion. The test kit also comprises a lateral flow device that comprises a chromatographic medium and an absorbent material that receives the test sample after flowing through the chromatographic medium. The chromatographic medium defines a detection zone within which is contained a detection reagent consisting of a nucleophilic aromatic amine that is directly bound through covalent bonding to the chromatographic medium. The detection reagent is capable of reacting with the diazonium ion to form an indicator (e.g., azo compound). The indicator exhibits a color that is different than the color of the detection reagent.
摘要翻译：根据本公开的一个实施例，公开了用于检测测试样品中亚硝酸盐的存在或不存在的诊断测试试剂盒。测试试剂盒包括能够与亚硝酸盐反应形成重氮离子的芳族伯胺。测试试剂盒还包括侧流装置，其包括色谱介质和在流过色谱介质之后接收测试样品的吸收材料。色谱介质定义了一个检测区，其中含有由亲核芳族胺组成的检测试剂，其通过与色谱介质的共价键直接结合。检测试剂能够与重氮离子反应以形成指示剂（例如偶氮化合物）。指示剂显示与检测试剂的颜色不同的颜色。

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