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11. 发明申请

WO2011021717A3 METHOD FOR PRODUCING HYDROXYLATED AMINO ACIDS 审中-公开
公开(公告)号：WO2011021717A3
公开(公告)日：2011-02-24
申请号：PCT/JP2010/064323
申请日：2010-08-18
申请人： AJINOMOTO CO.,INC. , SMIRNOV, Sergey Vasilievich , SAMSONOVA, Natalia Nikolaevna , KOTLIAROVA, Veronika Aleksandrovna , RUSHKEVICH, Natalia Yurievna , FEDORINA, Ekaterina Aleksandrovna , SOKOLOV, Pavel Mikhailovich , KOLOKOLOVA, Aleksandra Viktorovna , OGAWA, Jun , HIBI, Makoto , SHIMIZU, Sakayu , IMABAYASHI, Yuki , SUZUKI, Shunichi , SUGIYAMA, Masakazu
发明人： SMIRNOV, Sergey Vasilievich , SAMSONOVA, Natalia Nikolaevna , KOTLIAROVA, Veronika Aleksandrovna , RUSHKEVICH, Natalia Yurievna , FEDORINA, Ekaterina Aleksandrovna , SOKOLOV, Pavel Mikhailovich , KOLOKOLOVA, Aleksandra Viktorovna , OGAWA, Jun , HIBI, Makoto , SHIMIZU, Sakayu , IMABAYASHI, Yuki , SUZUKI, Shunichi , SUGIYAMA, Masakazu
IPC分类号： C12N9/02 , C12P13/06
摘要： A method for manufacturing hydroxylated amino acid, particularily hydroxylated isoleucine, hydroxylated methionine, hydroxylated threonine, hydroxylated leucine or hydroxylated valine, by enzymatic conversion using a dioxygenase.

12. 发明申请

WO2007119575A1 NOVEL ALDOLASE AND PRODUCTION PROCESS OF 4-HYDROXY-L-ISOLEUCINE 审中-公开
标题翻译：新型羟基丙酸酯和4-羟基-L-己烯的生产方法
公开(公告)号：WO2007119575A1
公开(公告)日：2007-10-25
申请号：PCT/JP2007/056756
申请日：2007-03-22
申请人： AJINOMOTO CO., INC. , SMIRNOV, Sergey, Vasilievich , SAMSONOVA, Natalia, Nikolaevna , KODERA, Tomohiro , MATSUI, Kazuhiko
发明人： SMIRNOV, Sergey, Vasilievich , SAMSONOVA, Natalia, Nikolaevna , KODERA, Tomohiro , MATSUI, Kazuhiko
IPC分类号： C12N9/88 , C12P13/06
CPC分类号： C12N9/88 , C12P13/06
摘要： A novel aldolase is described. 4-hydroxy-3-methyl-2-keto-pentanoic acid, which is useful as an intermediate in the synthesis of 4-hydroxy-L-isoleucine, may be synthesized from acetaldehyde and α-ketobutyric acid using a novel aldolase, which is derived from the genus Arthrobacter.
摘要翻译：描述了一种新的醛缩酶。可用作合成4-羟基-L-异亮氨酸的中间体的4-羟基-3-甲基-2-酮 - 戊酸可以使用新的醛缩酶由乙醛和α-酮丁酸合成，其是衍生自节杆菌属。

13. 发明申请

WO2008044614A1 METHOD FOR PRODUCING 4-HYDROXY-L-ISOLEUCINE 审中-公开
标题翻译：生产4-羟基-L-肉桂酸的方法
公开(公告)号：WO2008044614A1
公开(公告)日：2008-04-17
申请号：PCT/JP2007/069520
申请日：2007-09-28
申请人： AJINOMOTO CO., INC. , KODERA, Tomohiro , SMIRNOV, Sergey Vasilievich , SAMSONOVA, Natalia Nikolaevna , KOTLIAROVA, Veronika Aleksandrovna , RUSHKEVICH, Natalia Yurievna , KOZLOV, Yury Ivanovich , SHIMIZU, Sakayu , OGAWA, Jun , HIBI, Makoto
发明人： KODERA, Tomohiro , SMIRNOV, Sergey Vasilievich , SAMSONOVA, Natalia Nikolaevna , KOTLIAROVA, Veronika Aleksandrovna , RUSHKEVICH, Natalia Yurievna , KOZLOV, Yury Ivanovich , SHIMIZU, Sakayu , OGAWA, Jun , HIBI, Makoto
IPC分类号： C12P13/06 , C12N9/02
CPC分类号： C12N9/0069 , C12P13/06
摘要： Novel highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof comprising reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating produced (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
摘要翻译：提供了来自苏云金芽孢杆菌的新型高活性L-异亮氨酸双加氧酶。一种制备（2S，3R，4S）-4-羟基-L-异亮氨酸或其盐的方法，其包括在L-异亮氨酸双加氧酶存在下在水性溶剂中反应L-异亮氨酸并分离（2S，3R，4S）还提供了4-羟基-L-异亮氨酸。

14. 发明申请

WO2006135277A3 DEVICE FOR CUTTING THERMOPLASTIC MATERIALS 审中-公开
标题翻译：切割热塑性材料的装置
公开(公告)号：WO2006135277A3
公开(公告)日：2007-04-05
申请号：PCT/RU2006000289
申请日：2006-06-01
申请人： SMIRNOV SERGEY VLADIMIROVICH
发明人： SMIRNOV SERGEY VLADIMIROVICH
IPC分类号： B26F3/12 , B26D1/547 , B26D1/553
CPC分类号： B26F3/12 , B26D1/547 , B26D1/553 , B26D3/006 , B26D3/10
摘要： The inventive device for cutting thermoplastic materials comprises a base (1), a heatable cutting tool which is movable in vertical and horizontal planes and mounted on the carriages (7) of vertical rails (4) which are arranged on the carriages (3) of horizontal tails (2) in such a way that they are synchronously displaceable. The heatable cutting tool is provided with several cutting wires (8) or an interchangeable tool, which is provided with the specifically shaped cutting wire (8) arranged on a guide (24). An individual motor (14), which makes it possible to synchronously displace several cutting wires (8) and increase a cutting accuracy, is positioned on the top beam (5) of a movable gantry (6). A computer (21) controls the cutting of thermoplastic materials.
摘要翻译：用于切割热塑性材料的本发明的装置包括基座（1），可加热切割工具，其可在垂直和水平平面中移动并且安装在垂直导轨（4）的托架（7）上，所述托架（7）布置在托架（3）水平尾部（2）以这样一种方式同步移动。可加热切割工具设置有多个切割线（8）或可互换工具，其设置有布置在引导件（24）上的特定形状的切割线（8）。位于可移动机架（6）的顶梁（5）上的单个马达（14）能够使多个切割线（8）同时移位并提高切割精度。计算机（21）控制热塑性材料的切割。

15. 发明申请

WO2011021717A2 METHOD FOR PRODUCING HYDROXYLATED AMINO ACIDS 审中-公开
标题翻译：生产羟基氨基酸的方法
公开(公告)号：WO2011021717A2
公开(公告)日：2011-02-24
申请号：PCT/JP2010064323
申请日：2010-08-18
申请人： AJINOMOTO KK , SMIRNOV SERGEY VASILIEVICH , SAMSONOVA NATALIA NIKOLAEVNA , KOTLIAROVA VERONIKA ALEKSANDROVNA , RUSHKEVICH NATALIA YURIEVNA , FEDORINA EKATERINA ALEKSANDROVNA , SOKOLOV PAVEL MIKHAILOVICH , KOLOKOLOVA ALEKSANDRA VIKTOROVNA , OGAWA JUN , HIBI MAKOTO , SHIMIZU SAKAYU , IMABAYASHI YUKI , SUZUKI SHUNICHI , SUGIYAMA MASAKAZU
发明人： SMIRNOV SERGEY VASILIEVICH , SAMSONOVA NATALIA NIKOLAEVNA , KOTLIAROVA VERONIKA ALEKSANDROVNA , RUSHKEVICH NATALIA YURIEVNA , FEDORINA EKATERINA ALEKSANDROVNA , SOKOLOV PAVEL MIKHAILOVICH , KOLOKOLOVA ALEKSANDRA VIKTOROVNA , OGAWA JUN , HIBI MAKOTO , SHIMIZU SAKAYU , IMABAYASHI YUKI , SUZUKI SHUNICHI , SUGIYAMA MASAKAZU
IPC分类号： C12N9/02
CPC分类号： C12P13/06 , C12N9/0071 , C12P13/08 , C12P13/12
摘要： A method for manufacturing hydroxylated amino acid, particularily hydroxylated isoleucine, hydroxylated methionine, hydroxylated threonine, hydroxylated leucine or hydroxylated valine, by enzymatic conversion using a dioxygenase.
摘要翻译：通过使用双加氧酶的酶转化来制造羟基化氨基酸，特别是羟基化的异亮氨酸，羟基化甲硫氨酸，羟基化苏氨酸，羟基化亮氨酸或羟基化缬氨酸的方法。

16. 发明申请

WO2009082028A2 PROCESS FOR PRODUCING (2S,3R,4S)-4-HYDROXY-L-ISOLEUCINE 审中-公开
标题翻译：生产（2S，3R，4S）-4-羟基-L-异亮氨酸的方法
公开(公告)号：WO2009082028A2
公开(公告)日：2009-07-02
申请号：PCT/JP2008/073913
申请日：2008-12-22
申请人： AJINOMOTO CO., INC. , SMIRNOV, Sergey, Vasilievich , SAMSONOVA, Natalia, Nikolaevna , KOTLIAROVA, Veronika, Aleksandrovna , RUSHKEVICH, Natalia, Yurievna , BEZNOSCHENKO, Olga, Sergeevna
发明人： SMIRNOV, Sergey, Vasilievich , SAMSONOVA, Natalia, Nikolaevna , KOTLIAROVA, Veronika, Aleksandrovna , RUSHKEVICH, Natalia, Yurievna , BEZNOSCHENKO, Olga, Sergeevna
IPC分类号： C12N1/00
CPC分类号： C12N9/0069 , C12P13/06
摘要： A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof using an L-isoleucine producing bacterium transformed with a DNA fragment containing a gene coding for a protein having L-isoleucine dioxygenase activity; and having the ability to produce (2S,3R,4S)-4-hydroxy-L-isoleucine.
摘要翻译：使用产生L-异亮氨酸的细菌用含有编码蛋白质的基因的DNA片段转化的（2S，3R，4S）-4-羟基-L-异亮氨酸或其盐的制造方法具有L-异亮氨酸双加氧酶活性; 并具有生产（2S，3R，4S）-4-羟基-L-异亮氨酸的能力。

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