专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO0151640A3 REGULATION OF HUMAN MITOCHONDRIAL TRANSFORMYLASE 审中-公开
标题翻译：人类线粒体转化酶的调控
公开(公告)号：WO0151640A3
公开(公告)日：2001-12-20
申请号：PCT/EP0100294
申请日：2001-01-11
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K38/00 , A61K48/00 , C12N9/10 , C12N15/54 , A61K38/45 , A61P35/00 , C12N5/10 , C12N15/63 , C12P21/00 , C12Q1/48 , C12Q1/68
CPC分类号： C12N9/1014 , A61K38/00 , A61K48/00
摘要： Reagents which regulate human mitochondrial transformylase and reagents which bind to human mitochondrial transformylase gene products can be used to regulate cell proliferation, particularly in diseases such as cancer and other forms of neoplasia.
摘要翻译：调节人线粒体转甲酰酶的试剂和与人线粒体转甲酰基酶产物结合的试剂可用于调节细胞增殖，特别是在疾病如癌症和其他形式的瘤形成中。

12. 发明申请

WO0170954A2 REGULATION OF HUMAN NERVE GROWTH FACTOR-ELATED G PROTEIN-COUPLED RECEPTOR 审中-公开
标题翻译：人神经生长因子调节G蛋白偶联受体
公开(公告)号：WO0170954A2
公开(公告)日：2001-09-27
申请号：PCT/EP0103337
申请日：2001-03-23
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K38/00 , C07K14/705 , C12N15/12 , C12N15/11 , A61K31/711 , A61K38/17 , C12N9/00 , C12Q1/68 , G01N33/68
CPC分类号： C07K14/705 , A61K38/00
摘要： Reagents which regulate human nerve growth factor-related G protein-coupled receptor (NGFR-GPCR) protein and reagents which bind to human NGFR-GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, cancers, anorexia, bulimia, asthma, urinary incontinence, osteoporosis, ulcers, allergies, benign prostatic hypertrophy, and central or peripheral nervous system diseases, for example in primary and secondary disorders after brain injury, disorders of mood, anxiety disorders, disorders of thought and volition, disorders of sleep and wakefulness, diseases of the motor unit like neurogenic and myopathic disorders, neurodegenerative disorders like Alzheimer's and Parkinson's disease, disorders leading to peripheral and chronic pain.
摘要翻译：调节人神经生长因子相关G蛋白偶联受体（NGFR-GPCR）蛋白的试剂和与人NGFR-GPCR基因产物结合的试剂可以在预防，改善或纠正功能障碍或疾病中发挥作用，包括但不限于细菌，真菌，原生动物和病毒感染等感染，特别是艾滋病病毒，癌症，厌食症，贪食症，哮喘，尿失禁，骨质疏松症，溃疡，过敏，良性前列腺肥大和中枢或周围神经系统疾病引起的感染，例如脑损伤后的原发性和继发性疾病，情绪障碍，焦虑障碍，思想障碍和睡眠障碍，睡眠障碍和觉醒症，运动单位的疾病如神经源性和肌病性疾病，神经变性疾病如阿尔茨海默病和帕金森病，导致周围和慢性疼痛的疾病。

13. 发明申请

WO0202797A3 REGULATION OF HUMAN 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1-LIKE ENZYME 审中-公开
标题翻译：人类11羟甲基脱氢酶1样酶的调控
公开(公告)号：WO0202797A3
公开(公告)日：2003-02-27
申请号：PCT/EP0107632
申请日：2001-07-04
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： G01N33/50 , A61K31/7088 , A61K38/00 , A61K38/44 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/16 , A61P3/04 , A61P3/10 , A61P9/00 , A61P15/00 , A61P19/10 , A61P25/00 , A61P43/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/02 , C12N9/04 , C12N15/09 , C12N15/53 , C12Q1/02 , C12Q1/26 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/573 , A61K39/39 , C12N15/11 , C12N15/62 , G01N33/68
CPC分类号： C12N9/0006 , A61K38/00 , C12Y101/01146
摘要： Reagents which regulate human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme and reagents which bind to human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to CNS disorders, osteoporosis, liver disease, obesity, blood pressure or fetal development abnormalities, and diabetes.
摘要翻译：调节人11β-羟类固醇脱氢酶1样酶的试剂和与人11β-羟基类固醇脱氢酶1样酶基因产物结合的试剂可以在预防，改善或纠正功能障碍或疾病中发挥作用，包括但不限于中枢神经系统疾病，骨质疏松症，肝脏疾病，肥胖症，血压或胎儿发育异常以及糖尿病。

14. 发明申请

WO0192297A3 REGULATION OF HUMAN LGR4-LIKE G PROTEIN-COUPLED RECEPTOR 审中-公开
标题翻译：人类LGR4样G蛋白偶联受体的调控
公开(公告)号：WO0192297A3
公开(公告)日：2002-12-19
申请号：PCT/EP0106089
申请日：2001-05-29
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K38/00 , C07K14/705 , C12N1/21 , C12N15/12 , A61K45/00 , C12N5/10 , C12Q1/68 , G01N33/50
CPC分类号： C07K14/705 , A61K38/00
摘要： Reagents which regulate human LGR4-like G protein-coupled receptor (LGR4-like GPCR) and reagents which bind to human LGR4-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases in which G protein-coupled receptors are implicated including, but not limited to, obesity and diseases related to obesity, cancer, diabetes, osteoporosis, anxiety, depression, hypertension, migraine, compulsive disorders, schizophrenia, autism, neurodegenerative disorders, such as Alzheimer's disease, Parkinsonism, and Huntington's chorea, and cancer chemotherapy-induced vomiting.
摘要翻译：调节人类LGR4样G蛋白偶联受体（LGR4样GPCR）的试剂和与人LGR4样GPCR基因产物结合的试剂可以在预防，改善或纠正功能障碍或其中G蛋白偶联的疾病中发挥作用受体涉及，包括但不限于与肥胖症，癌症，糖尿病，骨质疏松症，焦虑症，抑郁症，高血压，偏头痛，强迫症，精神分裂症，孤独症，神经退行性疾病如阿尔茨海默氏病，帕金森综合征和亨廷顿氏症有关的肥胖症和疾病舞蹈病和癌症化疗引起的呕吐。

15. 发明申请

WO0173077A3 REGULATION OF HUMAN SERINE RACEMASE ENZYME 审中-公开
标题翻译：人类血清培养基的调控
公开(公告)号：WO0173077A3
公开(公告)日：2002-10-03
申请号：PCT/EP0103668
申请日：2001-03-30
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K31/713 , A61K38/00 , C12N9/90 , C12N15/61 , C12N15/70 , C12Q1/68 , G01N33/68
CPC分类号： C12Y501/01018 , A61K31/713 , A61K38/00 , C12N9/90
摘要： Human serine racemase enzyme can be regulated to increase or decrease D-serine formation, which thereby results in a corresponding increase or decrease in NMDA receptor activation. A decrease in D-serine formation may aid in the prevention of neuron damage following an ischemic event, such as stroke. Regulation of D-serine formation may also aid in the treatment of other neurodegenerative conditions caused by the over- or under-activation of the glutamate NMDA receptor.
摘要翻译：可以调节人丝氨酸消旋酶以增加或减少D-丝氨酸形成，从而导致NMDA受体活化的相应增加或减少。 D-丝氨酸形成的减少有助于预防缺血事件如中风后的神经元损伤。 D-丝氨酸形成的调节也可能有助于治疗由谷氨酸NMDA受体的过度活化或过度活化引起的其他神经变性病症。

16. 发明申请

WO0202755A3 REGULATION OF HUMAN THIMET OLIGOPEPTIDASE-LIKE ENZYME 审中-公开
标题翻译：人类胸腺寡核苷酸样酶的调节
公开(公告)号：WO0202755A3
公开(公告)日：2002-08-22
申请号：PCT/EP0107634
申请日：2001-07-04
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61P9/00 , A61P9/10 , A61P19/10 , A61P25/28 , A61P29/00 , A61P31/12 , A61P35/00 , C12N9/64 , C12N15/52 , A61K31/713 , A61K38/48 , A61K39/395 , C07K16/40 , C12N15/11 , C12N15/62 , C12Q1/68 , G01N33/573 , G01N33/68
CPC分类号： C12N9/6489
摘要： Reagents which regulate human thimet oligopeptidase-like enzyme and reagents which bind to human thimet oligopeptidase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer and neurodegenerative diseases, such as Alzheimer's disease.
摘要翻译：调节人类thimet寡肽酶样酶的试剂和结合人类thimet寡肽酶样酶基因产物的试剂可以在预防，改善或纠正功能障碍或疾病中发挥作用，所述功能障碍或疾病包括但不限于癌症和神经退行性疾病，例如阿尔茨海默氏病。

17. 发明申请

WO0200853A3 REGULATION OF HUMAN CASPASE-1-LIKE PROTEASE 审中-公开
标题翻译：人类caspase-1样蛋白酶的调节
公开(公告)号：WO0200853A3
公开(公告)日：2002-08-08
申请号：PCT/EP0107287
申请日：2001-06-26
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K38/00 , C12N9/64 , C12N15/55 , A61K38/43 , A61K39/395 , A61K48/00 , C07K16/40 , C12N9/00 , C12N15/11 , C12N15/62 , C12Q1/68 , G01N33/68
CPC分类号： C12N9/6475 , A61K38/00 , C07K2319/00 , C12Y304/22036
摘要： Reagents which regulate human caspase-1-like protease activity and reagents which bind to human caspase-1-like protease gene products can be used to treat an allergic disease, asthma, cancer and neurodegenerative diseases.
摘要翻译：调节人类半胱天冬酶-1样蛋白酶活性的试剂和结合人类半胱氨酸蛋白酶样蛋白酶基因产物的试剂可用于治疗过敏性疾病，哮喘，癌症和神经退行性疾病。

18. 发明申请

WO0168839A9 REGULATION OF HUMAN LIPOXIN A4 RECEPTOR-LIKE PROTEIN 审中-公开
标题翻译：人脂氧素A4受体样蛋白的调节
公开(公告)号：WO0168839A9
公开(公告)日：2002-07-18
申请号：PCT/EP0102729
申请日：2001-03-12
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K38/00 , A61P9/00 , A61P37/08 , C07K14/705 , C12N15/12 , G01N33/566 , G01N33/88 , A61K38/17 , C07K14/72 , C12N1/21 , C12N5/10 , C12Q1/68
CPC分类号： G01N33/566 , A61K38/00 , C07K14/705 , G01N33/88 , G01N2333/726 , G01N2500/10
摘要： Reagents which regulate human lipoxin A4 receptor-like protein and reagents which bind to human lipoxin A4 receptor-like gene products can be used to affect hemostasis, vascular reactivity, especially vasoconstriction, and inflammatory processes, including anaphylactic and other allergic reactions.
摘要翻译：调节人类脂氧素A4受体样蛋白的试剂和与人类脂氧素A4受体样基因产物结合的试剂可用于影响止血，血管反应性，特别是血管收缩和炎症过程，包括过敏性和其他过敏性反应。

19. 发明申请

WO0204608A3 REGULATION OF HUMAN OLIGOPEPTIDASE A-LIKE ENZYME 审中-公开
标题翻译：人类寡肽类似物酶的调节
公开(公告)号：WO0204608A3
公开(公告)日：2002-06-20
申请号：PCT/EP0107583
申请日：2001-07-03
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K38/00 , A61K39/00 , A61K48/00 , C12N9/64 , C12N9/00
CPC分类号： C12N9/6416 , A61K38/00 , A61K39/00 , A61K48/00
摘要： Reagents which regulate human oligopeptidase A-like enzyme and reagents which bind to human oligopeptidase A-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer.
摘要翻译：调节人类寡肽酶A样酶的试剂和与人类寡肽酶A样酶基因产物结合的试剂可以在预防，改善或纠正功能障碍或疾病（包括但不限于癌症）中发挥作用。

20. 发明申请

WO0192310A3 REGULATION OF HUMAN TRANSKETOLASE-LIKE ENZYME 审中-公开
标题翻译：人类转铁蛋白酶样酶的调控
公开(公告)号：WO0192310A3
公开(公告)日：2002-04-11
申请号：PCT/EP0106125
申请日：2001-05-30
申请人： BAYER AG , RAMAKRISHNAN SHYAM
发明人： RAMAKRISHNAN SHYAM
IPC分类号： A61K48/00 , C12N9/10 , C12N15/54 , A61K38/45 , C12N1/21 , C12Q1/68 , G01N33/573
CPC分类号： C12N9/1022 , A61K48/00 , C07K2319/00
摘要： Reagents which regulate human transketolase-like enzyme and reagents which bind to human transketolase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, anemia, and end-stage renal disease, including sensory periphery neuropathy associated with uremia.
摘要翻译：调节人类转酮醇酶样酶的试剂和与人类转酮酶样酶基因产物结合的试剂可以在预防，改善或纠正功能障碍或疾病中发挥作用，包括但不限于癌症，贫血和终末期肾脏疾病，包括与尿毒症相关的感觉性周围神经病变。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式