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    • 17. 发明申请
    • SOLUTION OF MENTHANE CARBOXAMIDES FOR USE IN CONSUMER PRODUCTS
    • 用于消费品中的疏水性碳酰胺的溶液
    • WO2010019729A1
    • 2010-02-18
    • PCT/US2009/053633
    • 2009-08-13
    • THE PROCTER & GAMBLE COMPANYHAUGHT, John, Christian
    • HAUGHT, John, Christian
    • A61K8/33A61K8/40A61Q13/00
    • A61Q11/00A23G9/06A61K8/42A61K2800/244A61Q9/02A61Q19/10
    • Disclosed is a stock solution of coolant materials for use in formulating consumer products comprising at least about 5% of one or a mixture of menthane carboxamide coolant materials and a solvent having individual Hansen solubility parameters of a dispersion force component (deltaD) ranging from about 15.2 to 21.2 (MPa) 0.5, a polar component (deltaP) ranging from about 0 to 10.8 (MPa) 0.5 and a hydrogen bonding component (deltaH) ranging from about 0 to 19.1 (MPa) 0.5. Preferably the menthane carboxamide is N- (4-cyanomethyl)phenyl-2-isopropyl-5-methylcyclohexanecarboxamide and the solvent is selected from benzaldehyde, benzyl alcohol, benzyl salicylate, alpha amyl cinnamic aldhehyde, cuminylaldehyde, para-Tolualdehyde, 2, 5-dimethyl Pyrazine, 2,3-dimethyl Pyrazine, neryl acetate, isoamyl propionate, menthone, carvacrol, propyl acetate, 2-ethylhexyl acetate, bornyl acetate, butyl acetate, dimethal benzyl carbinol acetate, cis-hexenyl acetate, trans-hexenyl acetate, menthyl acetate, isopulegol, ethyl amyl ketone, parcresyl methyl ether, ethyl oenanthate, isobutyl salicylate, terpinolene, geranyl acetate, hexyl acetate and dipentene.
    • 公开了一种用于配制消费品的冷却剂材料的储备溶液,其包含至少约5%的薄荷烷羧酰胺冷却剂材料的一种或其混合物和具有约15.2的分散力组分(δD)的单独Hansen溶解度参数的溶剂 至21.2(MPa)0.5,范围为约0至10.8(MPa)0.5的极性组分(δP)和约0至19.1(MPa)0.5的氢键组分(δH)。 优选地,薄荷烷甲酰胺是N-(4-氰基甲基)苯基-2-异丙基-5-甲基环己烷甲酰胺,溶剂选自苯甲醛,苯甲醇,水杨酸苄酯,α-戊基肉桂醛,檀香醛,对 - 戊二醛, 二甲基吡嗪,2,3-二甲基吡嗪,乙酸橙花酯,丙酸异戊酯,薄荷酮,香芹酚,乙酸丙酯,乙酸2-乙基己酯,乙酸冰片酯,乙酸丁酯,乙酸二甲酯苄醇,乙酸顺式己烯酯,乙酸异戊烯酯, 乙酸戊酯,对甲基甲基醚,羟基花环酯,水杨酸异丁酯,萜品醇烯醇,乙酸香叶酯,乙酸己酯和二戊烯。