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11. 发明申请

WO2018078209A1 SISTEMA DE DETECCIÓN DE RADIACIÓN GAMMA Y SISTEMA DE RESONANCIA MAGNÉTICA 审中-公开
标题翻译：伽马辐射检测系统和磁共振系统
公开(公告)号：WO2018078209A1
公开(公告)日：2018-05-03
申请号：PCT/ES2017/070720
申请日：2017-10-27
申请人： UNIVERSIDAD CARLOS III DE MADRID , SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
发明人： KONSTANTINOU, Georgios , VAQUERO LÓPEZ, Juan José , ALI, Wajahat , COSSU, Giulio , CIARAMELLA, Ernesto , CHIL PÉREZ, Rigoberto
IPC分类号： G01T1/164 , G01T1/29
CPC分类号： G01T1/164 , G01T1/29
摘要： Sistema de detección de radiación gamma, que comprende menos un detector de radiación gamma con un cristal centelleador, al menos un detector de fotones, un dispositivo de procesamiento analógico de señal, un enlace analógico de comunicaciones ópticas inalámbricas, una estación base y un aislamiento electromagnético en forma de jaula de Faraday. Además se describe un sistema de resonancia magnética que comprende el sistema de detección de radiación gamma anteriormente mencionado.
摘要翻译：伽马辐射检测系统包括更少的具有闪烁体晶体的伽马辐射检测器，至少一个光子检测器，模拟信号处理装置 ; al，无线通信的类似链路，基站和法拉第笼形式的电磁隔离。另外，描述了包括上述伽玛辐射检测系统的磁共振系统。

12. 发明申请

WO2017216740A1 JOINT FOR TRANSMITTING A TORSIONAL LOAD WITH ELASTIC RESPONSE 审中-公开
标题翻译：用弹性响应传递扭转负荷的联合
公开(公告)号：WO2017216740A1
公开(公告)日：2017-12-21
申请号：PCT/IB2017/053531
申请日：2017-06-14
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
发明人： VITIELLO, Nicola , GIOVACCHINI, Francesco , BALDONI, Andrea , CEMPINI, Marco
IPC分类号： F16D3/72 , F16F1/14
摘要： The object of the present invention is a new configuration of transmissive joint with elastic response for transmitting a torsional load capable, among other things, of ensuring the transmission also in the absence of coaxiality between the two actuating and actuated devices and allowing the internal passage of cabling or possible accessory components along the axis of transmission/torsion.
摘要翻译：本发明的目的在于提供一种具有弹性响应的用于传递扭转载荷的透射接头的新构造，其中尤其能够确保在两个致动元件之间没有同轴性的情况下传递驱动设备，并允许电缆或可能的附件组件沿传输/扭转轴的内部通道。

13. 发明申请

WO2014155338A1 METHOD AND DEVICE FOR MAKING FINGERPRINTS ASSOCIATED TO ARTIFICIAL FINGERS 审中-公开
标题翻译：制造与人工手指相关的手指的方法和装置
公开(公告)号：WO2014155338A1
公开(公告)日：2014-10-02
申请号：PCT/IB2014/060223
申请日：2014-03-27
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
发明人： MUSCOLO, Giovanni Gerardo , ODDO, Calogero Maria , CARROZZA, Maria Chiara , BECCAI, Lucia
IPC分类号： A61F2/58 , B29C39/14 , A61F2/50
CPC分类号： B29C39/146 , A61F2/5044 , A61F2/586 , A61F2002/5001 , A61F2002/5058 , A61F2002/7615 , B29C39/148
摘要： A method concerning a casting device for the application of a silicone coating to a sensorized item (10, 20) and designed to produce, in a simple and effective way, a silicon coating that imitates a fingerprint on its surface. The casting device comprises a casting shell (100), in which the sensorized item can be suitably locked, and a die (70, 70') provided with a forming surface, aimed at forming a recessed and/or relief pattern.
摘要翻译：一种用于向传感物品（10,20）施加硅氧烷涂层并且被设计为以简单而有效的方式制造模仿其表面上的指纹的硅涂层的铸造装置的方法。铸造装置包括铸造壳体（100），其中可以适当地锁定传感物件，以及设置有形成凹陷和/或浮雕图案的成形表面的模具（70,70'）。

14. 发明申请

WO2012028557A1 SWALLOWABLE CAPSULE FOR INSUFFLATION OF GASTROINTESTINAL TRACT 审中-公开
标题翻译：用于消除胃肠道疾病的易吸收性胶囊
公开(公告)号：WO2012028557A1
公开(公告)日：2012-03-08
申请号：PCT/EP2011/064764
申请日：2011-08-26
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA , VANDERBILT UNIVERSITY , VALDASTRI, Pietro , CIUTI, Gastone , MENCIASSI, Arianna , DARIO, Paolo , WEBSTER, Robert J. III , SMITH, Byron F. , TOENNIES, Jenna J.
发明人： VALDASTRI, Pietro , CIUTI, Gastone , MENCIASSI, Arianna , DARIO, Paolo , WEBSTER, Robert J. III , SMITH, Byron F. , TOENNIES, Jenna J.
IPC分类号： A61B1/32 , A61B1/04 , A61B1/12
CPC分类号： A61M13/003 , A61B1/00158 , A61B1/015 , A61B1/041
摘要： A system for insufflating a body cavity comprising a swallowable capsule comprising a chamber (11) containing a fluid capable to generate biocompatible gas or vapour by phase transition or chemical reaction, the chamber (11) being formed with at least one orifice (7) for placing it in communication with the outside. The orifice (7) is blocked by a shutter (4, 6; 26) made of magnetic material and there are provided elastic means (8) able to generate an elastic force sufficient to keep said shutter sealingly engaged in the orifice. The system further comprises magnetic actuating means (12; 34) external to the body cavity for generating a magnetic force having strength sufficient to overcome the elastic force of the elastic means disengaging the shutter from the orifice.
摘要翻译：一种用于吹入体腔的系统，包括可吞咽胶囊，其包括容纳能够通过相变或化学反应产生生物相容性气体或蒸汽的流体的腔室（11），所述腔室（11）形成有至少一个孔口（7），用于将其与外部通信。孔（7）被由磁性材料制成的活门（4,6; 26）阻挡，并且设置有弹性装置（8），该弹性装置能够产生足以使所述活门密封地接合在孔口中的弹性力。该系统还包括在体腔外部的磁性致动装置（12; 34），用于产生具有足以克服弹性装置将闸板从孔口分离的弹力的强度的磁力。

15. 发明申请

WO2011135503A1 ROBOTIC APPARATUS FOR MINIMALLY INVASIVE SURGERY 审中-公开
标题翻译：微型手术手术器械
公开(公告)号：WO2011135503A1
公开(公告)日：2011-11-03
申请号：PCT/IB2011/051772
申请日：2011-04-22
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA , SCARFOGLIERO, Umberto , QUAGLIA, Claudio , PICCIGALLO, Marco , TOGNARELLI, Selene , VALDASTRI, Pietro , MENCIASSI, Arianna , DARIO, Paolo
发明人： SCARFOGLIERO, Umberto , QUAGLIA, Claudio , PICCIGALLO, Marco , TOGNARELLI, Selene , VALDASTRI, Pietro , MENCIASSI, Arianna , DARIO, Paolo
IPC分类号： A61B19/00 , A61B1/313
CPC分类号： A61B19/2203 , A61B34/30 , A61B2017/2906 , A61B2034/305 , Y10T74/19907 , Y10T74/20305 , Y10T74/20335
摘要： A robotic arm (101, 102; 201, 202) especially suited for laparoscopic surgery, comprising a torsional joint (6) and a flexural joint (5) serially arranged, said joints (5, 6) providing respective degrees of freedom for said arm, the robotic arm receiving drive means (38, 39) for said flexural (5) and torsional (6) joints. The robotic arm further comprises transmission means (340, 350, 34-36) placed between the drive means (38, 39) and the joints (5, 6). The transmission means comprise a first (340) and a second (350) assembly of three gear wheels, preferably of the conical type, and a train of three additional gear wheels (34-36) preferably straight-cut gear wheels, which couple the first (340) and second (350) assembly to form a differential mechanism.
摘要翻译：特别适用于腹腔镜手术的机械臂（101,102; 201,202）包括扭转关节（6）和串联地设置的弯曲关节（5），所述关节（5,6）为所述臂提供相应的自由度所述机械手臂接收用于所述弯曲（5）和扭转（6）接头的驱动装置（38,39）。机器手臂还包括放置在驱动装置（38,39）和接头（5,6）之间的传动装置（340,350,34-36）。传动装置包括优选为锥形的三个齿轮的第一（340）和第二（350）组件，以及三个附加齿轮（34-36）的列，优选为直切齿轮，其连接第一（340）和第二（350）组件以形成差速机构。

16. 发明申请

WO2022137027A1 METHOD AND SYSTEM FOR INTERROGATING A BIREFRINGENT FIBER BRAGG GRATING SENSOR, EMPLOYING HETERODYNE OPTICAL DETECTION 审中-公开
公开(公告)号：WO2022137027A1
公开(公告)日：2022-06-30
申请号：PCT/IB2021/061767
申请日：2021-12-15
申请人： BREMBO S.P.A. , SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
发明人： FARALLI, Stefano , MUANENDA, Yonas Seifu , DI PASQUALE, Fabrizio , TOZZETTI, Lorenzo , CAMOZZI, Francesco
IPC分类号： G01D5/353
摘要： A method for interrogating at least one sensor of the birefringent Fiber Bragg Grating type, Bi-FBG is described. Such a method firstly comprises the steps of illuminating said at least one sensor of the birefringent Fiber Bragg Grating type, Bi-FBG, with a broadband optical excitation radiation OA; and conveying the reflected optical spectrum OR from the at least one sensor of the birefringent Fiber Bragg Grating type, Bi-FBG, to a detection photonic integrated circuit PIC. The method then includes separating a first component of the aforesaid reflected optical spectrum OR1, characterized by a first optical polarization generated by the birefringence and centered around a first frequency ω1, from a second component of the aforesaid reflected optical spectrum OR2, characterized by a second optical polarization generated by the birefringence and centered around a second frequency ω2, by means of a polarization optical beam splitter comprised in the detection photonic integrated circuit PIC. The method further comprises the steps of providing the aforesaid broadband optical excitation OA to the detection photonic integrated circuit PIC; and obtaining at least two narrowband optical signals (L01, L02), on the basis of at least one narrowband optical filtering of the aforesaid broadband optical excitation radiation OA carried out in the detection photonic integrated circuit PIC. The aforesaid at least two narrowband optical signals (L01, L02) comprise a first local oscillator optical signal L01, centered around a first local oscillator frequency ooi_oi, and a second local oscillator optical signal L02, centered around a second local oscillator frequency ωL02. The method then includes providing the aforesaid first component of the reflected optical spectrum OR1 and said first local oscillator optical signal L01 to first optical heterodyne detection means, integrated in the detection photonic integrated circuit PIC, to carry out a heterodyne detection and obtain a first electrical signal E1 at a first intermediate frequency ωIFs, equal to the difference between the first local oscillator frequency ωL01 and said first frequency ω1 of the first component of the reflected optical spectrum OR1. Similarly, the method further includes providing the aforesaid second component of the reflected optical spectrum OR2 and the aforesaid second local oscillator optical signal L02 to second optical heterodyne detection means, also integrated into said detection photonic integrated circuit PIC, to carry out a heterodyne detection and obtain a second electrical signal E2 at a second intermediate frequency ωIFf, equal to the difference between the second local oscillator frequency GULO2 and the aforesaid second frequency ω2 of the second component of the reflected optical spectrum OR2. The method finally comprises the steps of determining the first intermediate frequency ωIFs, indicative of a first wavelength shift Δλ1 of the first component of the reflected optical spectrum OR1, having the first polarization, with respect to a first reference wavelength λί of the Bragg grating of the sensor of the optical fiber sensor, Bi-FBG; and further determining the second intermediate frequency indicative of a second wavelength shift Δλ2 of the second component of the reflected optical spectrum OR2, having the second polarization, with respect to a second reference wavelength λί of the Bragg grating of the optical fiber sensor, Bi-FBG. The aforesaid first wavelength shift Δλ1 and second wavelength shift Δλ2 are representative of at least one physical magnitude measured by the optical fiber sensor Bi-FBG. Furthermore, a corresponding system for interrogating at least one sensor of the birefringent Fiber Bragg Grating, Bi-FBG, is described. Finally, a method and system are described for determining at least two physical magnitudes detectable by a sensor of the birefringent Fiber Bragg Grating, Bi-FBG, type, employing the aforementioned method of interrogating.

17. 发明申请

WO2022074632A1 A DEVICE FOR ENDOSCOPICALLY DELIVERING A THERAPEUTIC SUBSTANCE 审中-公开
公开(公告)号：WO2022074632A1
公开(公告)日：2022-04-14
申请号：PCT/IB2021/059279
申请日：2021-10-11
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
发明人： RICOTTI, Leonardo , VANNOZZI, Lorenzo , MAZZOCCHI, Tommaso , SILIBERTO, Alessio , GUARNERA, Daniele
IPC分类号： A61B17/34 , A61M25/01 , A61M25/00
摘要： A device for endoscopically delivering at least one therapeutic substance includes a cannula (10) defining at least one extrusion channel (11) and comprises a proximal portion (19), a flexible distal portion (15) having an extrusion mouth (16), and a substantially rigid intermediate portion (17) between the flexible distal portion (15) and the proximal portion (19). The proximal portion (19) is configured to feed and push a therapeutic substance into the extrusion channel (11), so that the latter can pass through the extrusion channel (11) flowing through the intermediate portion (17) and through the flexible distal portion (15) and can exit from the extrusion mouth (16). The device also comprises at least one actuation cable (50, 50', 50") having a proximal end (59) operable at the proximal portion (19) and a distal end (55) connected to the flexible distal portion (15) at the extrusion mouth (16), and configured to pull the flexible distal portion (15) with a force transversal to the extrusion channel (11), bringing the flexible distal portion (15) from an undeformed conformation (A) to a deformed conformation (B). According to the invention, the substantially rigid intermediate portion (17) has a distal rigid edge (54) from which the flexible distal portion protrudes (15), and in which the distal rigid edge (54) has a passageway exit (53) of a passageway (56) for the actuation cable (50), the distal rigid edge (54) and the passageway exit (53) of the passageway arranged in such a way that only the flexible distal portion (15) of the cannula (10) can be brought, by the actuation cable (50, 50', 50"), from the undeformed conformation (A) to the deformed conformation (B) while the intermediate portion (17) remains undeformed.

18. 发明申请

WO2021260614A1 ARTIFICIAL HEART MUSCLE 审中-公开
公开(公告)号：WO2021260614A1
公开(公告)日：2021-12-30
申请号：PCT/IB2021/055605
申请日：2021-06-24
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA , ACADEMISCH MEDISCH CENTRUM
发明人： CIANCHETTI, Matteo , LORENZON, Lucrezia , MASELLI, Martina , ZRINSCAK, Debora , KLUIN, Jolanda
IPC分类号： A61M60/196 , A61M60/268 , A61M60/427 , A61M60/438 , A61M60/837 , A61M60/873
摘要： An artificial ventricle (100) comprising at least one ventricular chamber (110) defined by a containment wall (115), said containment wall (115) having an inner surface (115a) and an outer surface (115b) and defining an inner volume V. The artificial ventricle (100) then comprises at least one active layer (120) arranged to externally wind the ventricular chamber (110), said or each active layer (120) comprising at least one fluidic actuator (125) arranged to exert a variable pressure Pvar on the containment wall (115) to cyclically pass the ventricular chamber (110) between a compressed configuration wherein there is V = Vc and an expanded configuration wherein there is V = Ve > Vc . In particular, the containment wall (115) is made of deformable material and, when passing from the expanded configuration to the compressed configuration, the containment wall (115) is adapted to form and/or to increase inner folds (116) for reducing the inner volume V.

19. 发明申请

WO2021161235A1 HIGH SAMPLING RATE OPTICAL FIBER SENSOR 审中-公开
公开(公告)号：WO2021161235A1
公开(公告)日：2021-08-19
申请号：PCT/IB2021/051166
申请日：2021-02-12
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - ISTITUTO TECIP
发明人： OTON, Claudio
IPC分类号： G01D5/353
摘要： An optical fiber sensor (100) comprises optical sensor elements (10), for instance a plurality of multiplexed Bragg gratings, a broadband optical source (20), an interferometer (30) comprising at least one polarization-maintaining fiber (31) section with which a birefringence modulator (60), a signal generator (40) and a receiver (50) are associated. The optical birefringence in the propagation medium, i.e. in the polarization-maintaining fibre (31), combined with the birefringence of the birefringence modulator (60), produce in the interferometer (30) the path difference and thereby the interference fringes which, appropriately processed according to the known technique, allow the measurement to be traced. The use of a birefringence modulator associated with the polarization-maintaining fiber allows a high-speed modulation of the interferometer, thus allowing high sampling rates of the sensor without having variations in responsivity depending on the alignment of the sensors with the interferential fringes of the interferometer.

20. 发明申请

WO2020174395A1 MATERIAL AND SYSTEM FOR THE THERAPEUTIC TREATMENT OF JOINTS 审中-公开
公开(公告)号：WO2020174395A1
公开(公告)日：2020-09-03
申请号：PCT/IB2020/051603
申请日：2020-02-25
申请人： VIMEX SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (VIMEX) , H&D WIRELESS AB , PLASMACHEM PRODUKTIONS UND HANDEL GMBH , IMAGE GUIDED THERAPY SA , ISTITUTO ORTOPEDICO RIZZOLI , BAR ILAN UNIVERSITY , SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
发明人： RICOTTI, Leonardo , VANNOZZI, Lorenzo , CAFARELLI, Andrea , NESSIM, Gilbert Daniel , LISIGNOLI, Gina , WECHSLER, Aharon , DUMONT, Erik Jean-Claude , JOST, Carsten , GAPINSKI, Tomasz , BERGSTEN, Pär , GABUSI, Elena , FINI, Milena , TSCHON, Matilde , RUSSO, Alessandro , ZAFFAGNINI, Stefano , MELICONI, Riccardo , FEDUTIK, Yirij , LENARTOWICZ, Krzysztof Stanislaw , JERNBERGER, Åke , SHACHAF, Yonatan , ERIKSSON, Magnus
IPC分类号： A61L27/38 , A61L27/44 , A61L27/52 , A61M37/00 , A61N1/20 , A61N1/32 , B82Y5/00
摘要： A system for the therapeutic treatment of joints comprising a composite material (10) arranged to the therapeutic treatment of joints, said composite material (10) comprising a biodegradable polymer matrix (11) and a plurality of piezoelectric particles (12) adapted to generate local electric charges in response to an external stimulation made by means of ultrasound, said plurality of piezoelectric particles (12) being dispersed in the matrix. The composite material (10) also comprises a plurality of stamina cells (13) dispersed in the biodegradable polymer matrix (11) and a plurality of carbon-based particles. The system also comprises a releasing device (20), arranged to deposit the composite material (10) in a joint cavity at predetermined areas of the cartilage, and a stimulator device (30) arranged to emit ultrasound at a predetermined frequency, a predetermined intensity and for a predetermined time of application, in such a way that, when the device is located near a joint wherein the composite material (10) has been deposited, said ultrasound stimulate the plurality of piezoelectric particles (12).

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