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    • 102. 发明申请
    • DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS
    • DIHYDROBENZOFURAN衍生物作为杀虫剂化合物
    • WO2014172871A1
    • 2014-10-30
    • PCT/CN2013/074708
    • 2013-04-25
    • SYNGENTA PARTICIPATIONS AGLU, Long
    • LU, LongCASSAYRE, Jérome YvesLUKSCH, TorstenEL QACEMI, MyriemWU, Yaming
    • C07D261/02A61K43/56
    • C07D307/79C07D405/12C07D491/048
    • The present invention relates to compounds of formula (I) wherein Q is (Q1) or (Q2) G 1 is oxygen or sulfur; Y 1 is oxygen, sulfur or CH 2 ; Y 2 , Y 3 and Y 4 are each independently C-H, C-R 5 or nitrogen, wherein no more than one of Y 2 , Y 3 and Y 4 is C-R 5 ; Y 5 is hydrogen, halogen, C 1 -C 8 alkyl, C 1 -C 8 haloalkyl or C 3 -C 8 cycloalkyl; Y 6 is hydrogen, halogen, cyano, C 1 -C 8 alkyl, C 1 -C 8 haloalkyl or C 3 -C 8 cycloalkyl; R 1a is hydrogen, C 1 -C 8 alkyl, C 1 -C 8 alkoxy, C 1 -C 8 alkylcarbonyl or C 1 -C 8 alkoxycarbonyl; R 1b is hydrogen, C 1 -C 8 alkyl, C 1 -C 8 alkylcarbonyl or C 1 -C 8 alkoxycarbonyl; R 3 is C 1 -C 8 haloalkyl; R 4 is aryl or aryl substituted by one to five R 10 , or heteroaryl or heteroaryl substituted by one to five R 10 ; R 6a is hydrogen, cyano, C 1 -C 8 alkyl, C 1 -C 8 haloalkyl or C 3 -C 8 cycloalkyl; R 6b is hydrogen, cyano, C 1 -C 8 alkyl, C 1 -C 8 haloalkyl or C 3 -C 8 cycloalkyl; or R 6a and R 6b together with the carbon atom to which they are attached may form a 3 to 6-membered carbocyclic ring; and R 2a , R 2b , R and R are as defined in the claims. The invention also relates to methods of controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula I.
    • 本发明涉及式(I)化合物,其中Q是(Q1)或(Q2)G1是氧或硫; Y1是氧,硫或CH2; Y2,Y3和Y4各自独立地为C-H,C-R5或氮,其中Y2,Y3和Y4中只有一个为C-R5; Y 5是氢,卤素,C 1 -C 8烷基,C 1 -C 8卤代烷基或C 3 -C 8环烷基; Y 6是氢,卤素,氰基,C 1 -C 8烷基,C 1 -C 8卤代烷基或C 3 -C 8环烷基; R1a是氢,C1-C8烷基,C1-C8烷氧基,C1-C8烷基羰基或C1-C8烷氧基羰基; R1b是氢,C1-C8烷基,C1-C8烷基羰基或C1-C8烷氧基羰基; R3是C1-C8卤代烷基; R4是被1至5个R10取代的芳基或芳基,或被1至5个R 10取代的杂芳基或杂芳基; R6a是氢,氰基,C1-C8烷基,C1-C8卤代烷基或C3-C8环烷基; R6b是氢,氰基,C1-C8烷基,C1-C8卤代烷基或C3-C8环烷基; 或R6a和R6b与它们所连接的碳原子一起可以形成3至6元碳环; 并且R 2a,R 2b,R和R如权利要求中所定义。 本发明还涉及控制昆虫,螨虫,线虫或软体动物的方法,其包括将有害生物施用于有害生物的场所或易受害虫攻击的植物,其杀虫,杀螨,杀线虫或软体动物有效量的 式I的化合物。
    • 105. 发明申请
    • PROCESS FOR THE DIASTEREOSELECTIVE PREPARATION OF RUTHENIUM COMPLEXES
    • 钌络合物的二异氰酸酯选择性制备方法
    • WO2014166777A1
    • 2014-10-16
    • PCT/EP2014/056495
    • 2014-04-01
    • SYNGENTA PARTICIPATIONS AG
    • LOTHSCHUETZ, ChristianSAINT-DIZIER, Alexandre Christian
    • C07F15/00
    • C07F15/0053B01J31/2409B01J2231/643B01J2531/821
    • The present invention relates to a process for the preparation of a compound of formula (I), wherein X is -CH 2 -, -CH 2 -CH 2 -, -CH 2 -CH 2 -CH 2 - or -CH 2 -CH 2 -CH 2 -CH 2 -; Y 1 is -CH 2 -; -CH2-CH 2 - or -NH-; Y 2 is NHR 7 or SH; wherein R 7 is hydrogen, C 1 -C 4 alkyl or phenyl; R- 1 and R 2 , independently from each other, represent aliphatic or aromatic groups; R 3 and R 4 , independently from each other, represent aliphatic or aromatic groups; R 5 and R 6 are each hydrogen or represent together with the carbon atoms to which they are bonded, a phenyl ring; which process comprises reacting a compound of formula II [RuCI 2 (R 8 )n]m (II), wherein n is 1 and m is > 1 which represents a polymeric structure if R 8 is a molecule containing two alkene or alkyne moieties coordinating in an hapto-2 coordination mode to the metal; or n is 4 and m is 1 if R 8 is a nitrogen, oxygen or sulfur containing molecule in which said nitrogen, oxygen or sulfur coordinate to the metal; in the presence of an inert solvent which boiling point is from 1 12°C to 165°C with a compound of formula (III), wherein R 5 , R 6 , Y 1 and Y 2 are as defined under formula I, and a phosphane of formula IV R3R4P-X-PR 1 R 2 (iv), wherein R 1 , R 2 , R 3 , R 4 and X are as defined under formula I.
    • 本发明涉及制备式(I)化合物的方法,其中X是-CH 2 - , - CH 2 -CH 2 - , - CH 2 -CH 2 - 或 - CH 2 -CH 2 -CH 2 - 。 Y1是-CH2-; -CH 2 -CH 2 - 或-NH-; Y2是NHR7或SH; 其中R 7是氢,C 1 -C 4烷基或苯基; R 1和R 2彼此独立地表示脂族或芳族基团; R 3和R 4彼此独立地表示脂族或芳族基团; R5和R6各自为氢或与它们所键合的碳原子一起表示苯环; 该方法包括使式II化合物[RuCl 2(R 8)n] m(II),其中n为1且m为> 1,其代表聚合物结构,如果R 8为含有在连接基中配位的两个烯烃或炔部分的分子 -2协调模式对金属; 如果R8是氮,氧或含硫分子,其中所述氮,氧或硫与金属配位,则n为4,m为1; 在沸点为112℃至165℃的惰性溶剂存在下,与式(III)化合物反应,其中R 5,R 6,Y 1和Y 2如式I所定义,和式IV的膦 R3R4P-X-PR1R2(iv),其中R1,R2,R3,R4和X如式I所定义。