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91. 发明申请

WO1991003737A1 MEANS FOR DIAGNOSING DEMYELINATING NEUROPATHIES, IN PARTICULAR MULTIPLE SCLEROSIS 审中-公开
标题翻译：用于诊断神经损伤的手段，特别是多发性硬化症
公开(公告)号：WO1991003737A1
公开(公告)日：1991-03-21
申请号：PCT/FR1990000638
申请日：1990-08-30
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ZANETTA, Jean-Pierre , WARTER, Jean-Marie , KUCHLER, Sabine , VINCENDON, Guy
IPC分类号： G01N33/564
CPC分类号： G01N33/564 , G01N33/6854 , G01N2800/285 , Y10S435/975 , Y10S436/811 , Y10S436/827 , Y10S436/828
摘要： The invention relates to the use of means for diagnosing demyelinating neuropathies, in particular multiple sclerosis (MS) of endogenous lectins having an affinity for glycanes which are rich in mannose, or their proteinic sub-units, said lectins or their sub-units being immunologically related respectively to the cerebellar soluble lectins (CSL) or their proteinic sub-units.

92. 发明申请

WO1991000589A1 MUSICAL INSTRUMENT WITH A BOW, MADE OF A COMPOSITE MATERIAL 审中-公开
标题翻译：具有BOW的音乐仪器，复合材料的制造
公开(公告)号：WO1991000589A1
公开(公告)日：1991-01-10
申请号：PCT/FR1990000501
申请日：1990-07-03
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , BESNAINOU, Charles , VAIEDELICH, Stéphane
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： G10D01/00
CPC分类号： G10D1/005
摘要： At least the sound board (1) consists of a thin wall in a composite material which includes the superposition of at least two layers (A, B, C, D etc.) on which long fibers, all lying in the same direction, have been laid. Said sound board has at least one of its surface covered with a covering material (Y, Z) whose density is considerably less than that of said fibers. The arrangement of fibre layers is such that the ratio longitudinal elasticity module/transversal elasticity module of the wall is at its maximum along the longitudinal axis of symmetry (9) of said wall, and decreases in the direction of the lateral edges of the instrument.
摘要翻译：至少声音板（1）由复合材料中的薄壁组成，其包括至少两层（A，B，C，D等）的叠加，其中长的纤维全部位于相同的方向上，具有已经铺设所述声板具有覆盖材料（Y，Z）的至少一个表面，其密度明显小于所述纤维的密度。纤维层的布置使得壁的纵向弹性模量/横向弹性模量的比例沿着所述壁的纵向对称轴线（9）处于其最大值，并且在仪器的侧边缘的方向上减小。

93. 发明申请

WO1988006811A1 PHASE LOCKED MODE LASER GENERATOR 审中-公开
标题翻译：相锁模式激光发生器
公开(公告)号：WO1988006811A1
公开(公告)日：1988-09-07
申请号：PCT/FR1988000100
申请日：1988-02-23
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , BARTHELEMY, Alain , MANEUF, Serge , FROEHLY, Claude
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： H01S03/108
CPC分类号： H01S3/1112 , H01S3/0805 , H01S3/08054 , H01S3/08059 , H01S2301/085
摘要： Laser generator comprising a phase locking device of the laser generator modes, disposed between the amplifying active medium (3) and the reflecting rear mirror (1) and provided with, on the one hand, a non-linear and non-dispersive medium (5) placed in contact with said rear mirror (1) and, on the other hand, devices (11- 16) for transforming a gaussian beam with symmetrical revolution, emitted by the amplifying medium, into a beam with a morphology adapted to soliton propagation in said non-linear medium (5). The use of acoustic-optical modulators is rendered unnecessary. Application to a very broad wavelength range.
摘要翻译：激光发生器包括激光发生器模式的锁相装置，设置在放大活性介质（3）和反射后反射镜（1）之间，一方面具有非线性和非分散介质（5 ），另一方面，用于将由放大介质发射的具有对称旋转的高斯光束变换成具有适于孤子传播的形状的光束的装置（11-16）所述非线性介质（5）。使用声光调制器是不必要的。应用于非常宽的波长范围。

94. 发明申请

WO1987006692A1 TEMPERATURE INDICATORS BASED ON POLYDIACETYLENIC COMPOUNDS 审中-公开
标题翻译：基于聚异氰酸酯化合物的温度指示剂
公开(公告)号：WO1987006692A1
公开(公告)日：1987-11-05
申请号：PCT/FR1987000145
申请日：1987-04-30
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , THIERRY, Annette , LE MOIGNE, Jacques
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： G01K11/16
CPC分类号： C08F38/00 , G01K11/16
摘要： The temperature indicators based on polydiacetylenic compounds are comprised of at least one polydiacetylenic compound presenting an irreversible thermochromism obtained by polymerization of a monomer having the formula (I): CH3-(CH2)n-C=C-C=C-(CH2)n'-CH3 wherein n and n' are similar or different integers comprised between 2 and 21, or a mixture of such monomers, the monomer or monomers being in a crystallized phase. Application: indication of a temperature change.
摘要翻译：基于聚二乙炔化合物的温度指示剂由至少一种具有通过聚合具有式（I）的单体获得的不可逆热色变的聚二乙炔化合物组成：CH 3 - （CH 2）n C = CC = C-（CH 2）n'-CH 3 其中n和n'是2和21之间的相似或不同的整数，或这些单体的混合物，单体或单体处于结晶相。应用：温度变化指示。

95. 发明申请

WO1986007057A1 METHYL DERIVATIVES OF METHYLATED BIS 7H PYRIDOCARBAZOLES AND FARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开
标题翻译：甲基化二硫化7H IS BA BA M M M M M M M M M M M M M M M M M M M M M
公开(公告)号：WO1986007057A1
公开(公告)日：1986-12-04
申请号：PCT/FR1986000183
申请日：1986-05-29
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ROQUES, Bernard , LE PECQ, Jean-Bernard
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Quaternary ammonium salt of a derivative of bis 7H pyridocarbazole having formula (IV); wherein R1 which is in position 11 on the corresponding aromatic ring is particularly hydrogen; R2 which is in position 10 on the ring represents particularly a group OH; R3 is particularly hydrogen; R4 is CH3; R5 is H; the chain Z has the following structure: -(CH2)n - W - (CH2)n'- wherein: n and n' vary from 2 to 6; W is as represented by formula (a), with X representing (CH2)m, O or S; m varying from 0 to 4. These compounds have an antitumoral activity.

96. 发明申请

WO1986000620A1 MOLECULE COMPRISING AT LEAST ONE PEPTIDIC SEQUENCE CARRYING AN EPITOPE 审中-公开
标题翻译：包含至少一个携带EPITOPE的肽序列的分子
公开(公告)号：WO1986000620A1
公开(公告)日：1986-01-30
申请号：PCT/FR1985000183
申请日：1985-07-02
申请人： INSTITUT PASTEUR , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , KOENEN, Michaël , SCHERF, Arthur , MÜLLER-HILL, Benno , MERCEREAU-PUIJALON, Odile , PEREIRA DA SILVA, Luiz
发明人： INSTITUT PASTEUR , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： C07K07/00
CPC分类号： C07K14/445 , A61K39/00 , C12Q1/6893 , G01N33/56905 , Y02A50/412
摘要： Molecule having at least one peptidic sequence carrying an epitope characteristic of a proteine produced by cells infected by the parasites of paludism. It is characterized in that it contains a peptidic sequence having the formula: X-glu-Y-Val-A-Glu-Val-Z-Pro wherein: X is Glu or Val, Y is Val, Leu or Ileu, Z is Val or Ile and A is Glu or Asp.

97. 发明申请

WO1985002104A1 QUICK OCCLUSION CONTROLLED DEVICE 审中-公开
标题翻译：快速监控控制设备
公开(公告)号：WO1985002104A1
公开(公告)日：1985-05-23
申请号：PCT/FR1984000258
申请日：1984-11-12
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE LOUIS PASTEUR (STRASBOURG I) , SPEICH, Jean-Pierre , ZOULOUMIAN, Pierre, Joseph
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE LOUIS PASTEUR (STRASBOURG I)
IPC分类号： A61B05/08
CPC分类号： A61M16/20 , A61B5/08 , A61B5/085 , A61M16/0858 , A61M2209/02
摘要： A quick occlusion controlled device particularly intended to evaluate the sensitivity of respiratory centres comprises a body (1) connected to the respiratory apparatus of the patient through a buccal connector (2), provided with a pressure tap (3). According to the invention, the device is characterized in that the body (1) comprises an inspiration connector (4) which opens into the inner volume of the body (1) through a valve (5), as well as a respiration connector (6) which opens into the inner volume of the body (1) through a second valve (7), said device being further provided with an occlusion means of both/either of the valves (5) and (7).
摘要翻译：特别旨在评估呼吸中枢的敏感性的快速阻塞控制装置包括通过设置有压力分接头（3）的颊部连接器（2）连接到患者的呼吸装置的主体（1）。根据本发明，该装置的特征在于，主体（1）包括通过阀（5）向主体（1）的内部容积以及呼吸连接器（6）打开的吸气连接器（4）），其通过第二阀（7）进入主体（1）的内部容积，所述装置还设置有两个/任一阀（5）和（7）的闭塞装置。

98. 发明申请

WO1984004858A1 ECHO SUPPRESSOR WITH ADAPTIVE DIGITAL FILTER FOR TRANSMISSION SYSTEM 审中-公开
标题翻译：具有自适应数字滤波器的ECHO抑制器用于传输系统
公开(公告)号：WO1984004858A1
公开(公告)日：1984-12-06
申请号：PCT/FR1984000140
申请日：1984-05-25
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , BONNET, Madeleine , MACCHI, Odile
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： H04B03/23
CPC分类号： H04B3/232
摘要： The echo suppressor which may be used in a system for the simultaneous bidirectional transmission by MAQ modulation or phase modulation between two remote sources on a same transmission medium or circuit (10) comprises an adaptive digital filter (13) which provides the estimation sigma k of the effective echo. The adaptation algorithm of the vector C of the coefficients in: wherein mu is a predetermined incrementing pitch, ak is the conjugated value of the local data signals, ek is the signal deprived of the echo and f is a predetermined function. The output signal of the filter is subtracted from the signal arriving by the transmission medium. A corrector circuit is arranged between the transmission medium (10) and the subtractor (14) of the adapted filter to transform the complex remote data into a substantially real or imaginary data, the function f being able to use the sign only of ek.
摘要翻译：可用于通过同一传输介质或电路（10）上的两个远程源之间的MAQ调制或相位调制的同时双向传输的系统中的回波抑制器包括：自适应数字滤波器（13），其提供有效回声。系数的矢量C的适应算法：其中mu是预定的增加音调，ak是局部数据信号的共轭值，ek是被消除回波的信号，f是预定函数。从传输介质到达的信号中减去滤波器的输出信号。校正器电路布置在适配滤波器的传输介质（10）和减法器（14）之间，以将复杂的远程数据转换为基本上实际或虚数据，函数f仅能够使用ek的符号。

99. 发明申请

WO1984000419A1 METHOD FOR DETERMINING THE BIO- AND/OR TECHNO-SYNTHETIC ORIGINS OF ORGANIC SUBSTANCES AND MEANS FOR THE IMPLEMENTATION THEREOF 审中-公开
标题翻译：用于确定有机物质的生物和/或技术合成原料的方法及其实施方法
公开(公告)号：WO1984000419A1
公开(公告)日：1984-02-02
申请号：PCT/FR1983000140
申请日：1983-07-08
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , BENGSCH, Eberhard, Richard , GRIVET, Jean-Philippe , SCHULTEN, Hans-Rolf
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IPC分类号： G01N24/08
CPC分类号： G01R33/46 , G01R33/465
摘要： Method for identifying and optionally carrying out a quantitative determination of the bio- and/or techno-synthetic origins of organic substances as a function of their global ratio and mainly of their characteristic matrix of intramolecular distribution of light, stable and magnetically active isotopes, particularly of carbon 13, characterized in that it comprises the determination of the positional isotopic distribution of at least one light, stable and magnetically active isotope other than the deuterium by quantitative nuclear magnetic resonance by Fourier transform. Application, determination of the bio- and/or techno-synthetic origin of organic substances and means for the implementation thereof.

100. 发明申请

WO1998020123A2 STABLE CELL LINES EXPRESSING THE CFTR PROTEIN OR A MUTANT OF THIS PROTEIN, TOOL FOR SELECTING MOLECULES HAVING AN EFFECT ON THE INTRACELLULAR TRANSPORT OF THESE PROTEINS 审中-公开
标题翻译：稳定的细胞系表达CFTR蛋白或该蛋白质的突变体，用于选择对这些蛋白质的细胞内运输有影响的分子的工具
公开(公告)号：WO1998020123A2
公开(公告)日：1998-05-14
申请号：PCT/EP1997006095
申请日：1997-11-04
申请人： INSTITUT CURIE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人： INSTITUT CURIE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , COSTA DE BEAUREGARD, Marie-Alyette , LOUVARD, Daniel , ROBINE, Sylvie , EDELMAN, Alexandre , CHESNOY-MARCHAIS, Dominique , CHEN, Ming , BUCHWALD, Manuel
IPC分类号： C12N15/12
CPC分类号： C07K14/4712 , C07K2319/00 , G01N2800/382
摘要： The invention relates to a recombinant nucleic acid, characterized in that it comprises: a nucleotide sequence encoding (coding sequence) the normal CFTR protein, an epitope sequence located at the 3' end of the abovementioned coding sequence, a strong promoter sequence capable of controlling the expression of the abovementioned coding sequence and epitope sequence, when they are integrated into a determined cell.
摘要翻译：本发明涉及重组核酸，其特征在于其包含：编码（编码序列）正常CFTR蛋白的核苷酸序列，位于上述编码序列3'端的表位序列，能够控制的强启动子序列当将它们整合到确定的细胞中时，上述编码序列和表位序列的表达。

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