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1. 发明申请

WO2017190972A1 ANTI-MICROBIAL COMPOSITIONS COMPRISING QUATERNARY ORGANOSILANE COMPOUNDS 审中-公开
标题翻译：包含季铵化有机硅烷化合物的抗微生物组合物
公开(公告)号：WO2017190972A1
公开(公告)日：2017-11-09
申请号：PCT/EP2017/059676
申请日：2017-04-24
申请人： Q SURGICAL LTD
发明人： KEMP, Andrew , PILLANS, Charles Melville
IPC分类号： A01N33/12 , A01N55/00
摘要： An antimicrobial composition comprising at least two quaternary ammonium compounds selected from: (i) a quaternary ammonium compound having the formula: A 4-n Si(R- NH a R 1 b Z)n and (ii) a quaternary ammonium compound having the formula: NHcR 1 dZ wherein in each of the at least two quaternary ammonium compounds A, R, R 1 , a, Z and n are independently selected, and: A is a member selected from the group consisting of alkoxy radicals, alkylether alkoxy radicals, and alkyl radicals; R is a divalent hydrocarbon radical; each R 1 is independently a member selected from the group consisting of benzyl, alkyl radicals, alkyl ether hydrocarbon radicals, hydroxyl-containing alkyl radicals, and nitrogen-containing hydrocarbon radicals; Z is a member selected from the group consisting of chloride, bromide, iodide, tosylate, hydroxide, sulfate and phosphate; a is 0, 1 or 2, b is 1, 2 or 3, and the sum of a and b is 3; c is 0, 1, 2 or 3, d is 1, 2, 3 or 4, and the sum of c and d is 4; and n is 1, 2 or 3; and wherein the composition comprises at least two quaternary ammonium compounds of formula (i). A method of making an anti-microbial composition, and a method of reducing the number of micro-organisms on a surface, are disclosed.
摘要翻译：包含至少两种季铵化合物的抗微生物组合物，所述季铵化合物选自：（i）具有下式的季铵化合物：A 4-n Si（R-NH _{（ii）具有下式的季铵化合物：NHcR 1dZ其中在式至少两种季铵化合物A，R，R 1，a，Z和n中的每一种都是独立选择的，并且：A是选自烷氧基，烷基醚，烷氧基和烷基; R是二价烃基; 每个R 1独立地为选自苄基，烷基，烷基醚烃基，含羟基的烷基和含氮烃基的成员; Z是选自氯化物，溴化物，碘化物，甲苯磺酸盐，氢氧化物，硫酸盐和磷酸盐的成员; a是0,1或2，b是1,2或3，并且a和b之和是3; c是0,1,2或3，d是1,2,3或4，并且c和d的总和是4; 并且n是1,2或3; 并且其中所述组合物包含至少两种式（i）的季铵化合物。公开了制备抗微生物组合物的方法和减少表面上的微生物数量的方法。}

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