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    • 2. 发明申请
    • THERMOCHROMIC RESPONSIVE ELASTIC POLYMER SUBSTRATE
    • 热致变色反应性弹性聚合物基材
    • WO2009069059A3
    • 2009-10-15
    • PCT/IB2008054910
    • 2008-11-21
    • KIMBERLY CLARK COMACDONALD JOHN GAVINMARTIN STEPHANIE M
    • MACDONALD JOHN GAVINMARTIN STEPHANIE M
    • C08J3/20
    • A61M25/1027A41D13/11A41D19/0027A41D19/0055A61B5/015A61F6/04C08K5/0041G01K11/12G01K2207/00C08L21/00C08L13/02
    • A material composition including a flexible, polymeric matrix and a reverse- thermochromic colorant is described. When subjected to a heat source, the polymeric material can change color from a pale or neutral color to a darker or more vibrant color of a Delta E (?E) change of >3. The reverse-thermochromic colorant exhibits a color change when exposed to a heat source within a period of about 30 seconds, and is observable by an unaided human eye under either natural daylight or ambient artificial normal lighting conditions. One or more different reverse-thermochromic colorants in combination may be incorporated. The polymeric matrix surrounds or encapsulates a solvatochromic dye molecule with a phenolate betaine structure. The polymeric matrix includes a dipole orientating agent that induces said solvatochromic dye to express locally when subjected to a temperature change. Various uses for the composition and articles that incorporate the composition are also described, in addition to a method of indicating the temperature of an object or environmental condition.
    • 描述了包括柔性聚合物基体和反向热致变色着色剂的材料组合物。 当经受热源时,聚合物材料可以将颜色从浅色或中性颜色改变为深色或更鲜艳的ΔE(ΔE)变化> 3的颜色。 反向热致变色着色剂在约30秒的时间内暴露于热源时表现出颜色变化,并且在自然日光下或环境人工正常照明条件下可由肉眼观察到。 可以结合一种或多种不同的反向热致变色着色剂。 聚合物基质围绕或包封具有酚盐甜菜碱结构的溶剂化变色染料分子。 聚合物基质包括偶极取向剂,其在受到温度变化时诱导所述溶剂化变色染料局部表达。 除了指示物体温度或环境条件的方法之外,还描述了掺入组合物的组合物和制品的各种用途。
    • 8. 发明申请
    • MICROBIAL DETECTION AND QUANTIFICATION
    • 微生物检测和量化
    • WO2006065350A3
    • 2006-08-10
    • PCT/US2005038416
    • 2005-10-24
    • KIMBERLY CLARK COMACDONALD JOHN GAVINMARTIN STEPHANIE MLYE JASON
    • MACDONALD JOHN GAVINMARTIN STEPHANIE MLYE JASON
    • C12Q1/04C12Q1/06
    • C12Q1/06C12Q1/04Y10T442/2566
    • A method for semi-quantitatively or quantitatively detecting the presence of a microbe in a sample is provided. The method utilizes a test dye that undergoes a detectable color change in the presence of one or more microbes. For example, in one embodiment, the test dye is a solvatochromic dye (e.g., Reichardt's dye) that responds to differences in polarity between microbe components (e.g., cell membrane, cytoplasm, etc.) and the environment outside the cell. Alternatively, other mechanisms may be wholly or partially responsible for the interaction between the dye and the microbe, such as acid-base reactions, redox reactions, and so forth. Regardless, the color of the test dye may be compared to the color of a control dye, wherein the color of the control dye corresponds to a known microbe concentration.
    • 提供了半定量或定量检测样品中微生物存在的方法。 该方法利用在一种或多种微生物存在下经历可检测颜色变化的测试染料。 例如,在一个实施方案中,测试染料是响应微生物组分(例如细胞膜,细胞质等)与细胞外环境之间极性差异的溶剂化变色染料(例如Reichardt染料)。 或者,其他机制可能是染料和微生物之间相互作用的全部或部分原因,如酸碱反应,氧化还原反应等。 无论如何,测试染料的颜色可以与对照染料的颜色进行比较,其中对照染料的颜色对应于已知的微生物浓度。