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1. 发明申请

WO2008037572A1 METHOD AND APPARATUS FOR INTEGRATING RELATIONAL AND HIERARCHICAL DATA 审中-公开
标题翻译：整合关系和分层数据的方法与装置
公开(公告)号：WO2008037572A1
公开(公告)日：2008-04-03
申请号：PCT/EP2007/059304
申请日：2007-09-05
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , IBM UNITED KINGDOM LIMITED , KHORLIN, Andrey , STROM, Robert, Evan , TIAN, Lu
发明人： KHORLIN, Andrey , STROM, Robert, Evan , TIAN, Lu
IPC分类号： G06F17/30
CPC分类号： G06F17/30908
摘要： Methods and apparatus for integrating relational and hierarchical data, schema definitions, and queries in a data processing system are provided. It is determined if one or more schema definit ions or one or more query expressions are provided as input to the data processing system. The one or more schema definitions are converted into an intermediate schema language component of an intermediate data language when one or more schema definitions are provided. The one or more query expressions are converted into an intermediate query language component of the intermediate data language when one or more query expressions are provided. The intermediate schema language component or the intermediate query language component is compiled in an intermediate data language processing engine into a run-time representation in accordance with a relational-hierarchical analysis.
摘要翻译：提供了在数据处理系统中集成关系和层次数据，模式定义和查询的方法和装置。确定是否提供了一个或多个模式定义离子或一个或多个查询表达式作为数据处理系统的输入。当提供一个或多个模式定义时，将一个或多个模式定义转换为中间数据语言的中间模式语言组件。当提供一个或多个查询表达式时，一个或多个查询表达式被转换成中间数据语言的中间查询语言组件。中间模式语言组件或中间查询语言组件根据关系分层分析在中间数据语言处理引擎中编译成运行时表示。

2. 发明申请

WO2018106938A1 CROSSLINKED COATINGS 审中-公开
公开(公告)号：WO2018106938A1
公开(公告)日：2018-06-14
申请号：PCT/US2017/065148
申请日：2017-12-07
申请人： PENDANT BIOSCIENCES, INC. , STEVENS, David M. , RUCKH, Timothy T. , ELMQUIST, C. Eric , TIAN, Lu
发明人： STEVENS, David M. , RUCKH, Timothy T. , ELMQUIST, C. Eric , TIAN, Lu
IPC分类号： C07C279/00 , A61K49/00 , A61K31/00 , A61K47/48
CPC分类号： C09D143/02 , A61L27/34 , A61L29/085 , A61L2400/10
摘要： The present disclosure is directed to polymeric coatings. The coatings can include a substrate-coordinating functionality as well as additional functionality for interacting with the surrounding environment. For example, the coatings can be functionalized for a variety of applications such as imparting antimicrobial properties on a substrate such as an implant; drug delivery; or as an adhesive layer between a substrate and an additional coating.

3. 发明申请

WO2010030739A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF 审中-公开
标题翻译：聚乙二醇脂质偶联物及其用途
公开(公告)号：WO2010030739A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/056455
申请日：2009-09-10
申请人： ABBOTT LABORATORIES , DANDE, Prasad A. , HANSEN, Todd M. , HUBBARD, Robert D. , KOHLBRENNER, William E. , LI, Leiming , SARTHY, Aparna V. , SHEN, Yu , TIAN, Lu , WADA, Carol K. , ZHAO, Xiaobin
发明人： DANDE, Prasad A. , HANSEN, Todd M. , HUBBARD, Robert D. , KOHLBRENNER, William E. , LI, Leiming , SARTHY, Aparna V. , SHEN, Yu , TIAN, Lu , WADA, Carol K. , ZHAO, Xiaobin
IPC分类号： A61K9/127 , A61K47/10 , A61K47/14
CPC分类号： A61K9/0019 , A61K9/0004 , A61K9/1271 , A61K9/1272 , A61K31/225 , A61K31/40 , A61K31/7105
摘要： Polyethylene glycol (PEG)-lipid conjugates, polyethylene glycol (PEG)-lipid conjugate based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
摘要翻译：公开了聚乙二醇（PEG） - 脂质缀合物，基于聚乙二醇（PEG） - 脂质缀合物的药物递送系统，制备它们的方法以及使用它们治疗疾病的方法。

4. 发明申请

WO2009129387A3 CATIONIC LIPIDS AND USES THEREOF 审中-公开
公开(公告)号：WO2009129387A3
公开(公告)日：2009-10-22
申请号：PCT/US2009/040803
申请日：2009-04-16
申请人： ABBOTT LABORATORIES , DANDE, Prasad, A. , HANSEN, Todd, M. , HUBBARD, Robert, D. , WADA, Carol, K. , TIAN, Lu , ZHAO, Xiaobin
发明人： DANDE, Prasad, A. , HANSEN, Todd, M. , HUBBARD, Robert, D. , WADA, Carol, K. , TIAN, Lu , ZHAO, Xiaobin
IPC分类号： C07C217/28 , C07C219/06 , C07C237/08 , C07C219/08 , C07C235/08 , C07C271/16 , C07D207/06 , C07D207/14 , C07D211/44 , C07D211/58 , C07D317/28 , C07D295/088 , C07D203/10 , C07D233/61 , A61K9/127
摘要： Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.

5. 发明申请

WO2008130702A1 LOGICAL PAGING AREAS 审中-公开
标题翻译：逻辑分页区
公开(公告)号：WO2008130702A1
公开(公告)日：2008-10-30
申请号：PCT/US2008/005133
申请日：2008-04-21
申请人： ALCATEL LUCNET , TIAN, Lu , RAYNAUD, Rene , ZHAO, Yong
发明人： TIAN, Lu , RAYNAUD, Rene , ZHAO, Yong
IPC分类号： H04Q7/38
CPC分类号： H04W68/00 , H04W8/12 , H04W28/08 , H04W60/04
摘要： Paging of a mobile device within a mobile pool area serviced by two or more mobile switching nodes is reduced using logical paging areas. The mobile pool area includes a plurality of location areas, each serviced by the two or more switching nodes. In addition, the mobile pool area is divided into multiple logical paging areas, in which each logical paging area includes at least two location areas. Upon receiving a mobile terminated call for the mobile device, if the location area of the mobile device is unknown, the logical paging area within which the mobile device is located is determined in order to page the mobile device and deliver the mobile terminated call to the mobile device.
摘要翻译：使用逻辑寻呼区域减少由两个或多个移动交换节点服务的移动池区域内的移动设备的寻呼。移动池区域包括多个位置区域，每个位置区域由两个或多个交换节点服务。此外，移动池区域被划分为多个逻辑寻呼区域，其中每个逻辑寻呼区域包括至少两个位置区域。在接收到针对移动设备的移动终止呼叫时，如果移动设备的位置区域是未知的，则确定移动设备所在的逻辑寻呼区域，以便寻址移动设备并将移动终止的呼叫传送到移动设备。

6. 发明申请

WO2009151553A1 METHOD FOR HANDLING ROAMING OF MOBILE DEVICE TO RESTRICTED AREA 审中-公开
标题翻译：用于处理移动设备到限制区域的方法
公开(公告)号：WO2009151553A1
公开(公告)日：2009-12-17
申请号：PCT/US2009/003376
申请日：2009-06-03
申请人： ALCATEL-LUCENT USA INC. , TIAN, Lu , ZHAO, Yong
发明人： TIAN, Lu , ZHAO, Yong
IPC分类号： H04W48/04
CPC分类号： H04W48/04 , H04W60/04
摘要： As a mobile device moves from one location area to another, the mobile device detects the different location identifiers broadcast by the wireless network(s) in those locations areas. The mobile device stores the location identifier for the last location area in which the mobile device was located. By comparing a received location identifier to the stored location identifier, the mobile device determines if the mobile device has entered a new location area. If so, the mobile device sends a location update request. In one embodiment, if the location update request is for a location area to which access by the mobile device is restricted, the network sends a communication to the mobile device that triggers the mobile device to update a location identifier stored at the mobile device to the location identifier for the restricted location area so that the mobile can update the network after entering/selecting a different location area.
摘要翻译：随着移动设备从一个位置区域移动到另一个位置区域，移动设备检测由那些位置区域中的无线网络广播的不同位置标识符。移动设备存储移动设备所在的最后位置区域的位置标识符。通过将接收到的位置标识符与存储的位置标识符进行比较，移动设备确定移动设备是否已经进入新的位置区域。如果是，则移动设备发送位置更新请求。在一个实施例中，如果位置更新请求是针对移动设备的访问受到限制的位置区域，则网络向触摸移动设备的移动设备发送通信，以将存储在移动设备处的位置标识符更新为用于受限位置区域的位置标识符，使得移动台可以在进入/选择不同位置区域之后更新网络。

7. 发明申请

WO2008033951A2 DELIVERY OF MOBILE TERMINATED CALL DURING INTER-VLR LOCATION UPDATE 审中-公开
标题翻译：在VLR位置更新期间交付移动终端呼叫
公开(公告)号：WO2008033951A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/078309
申请日：2007-09-12
申请人： ALCATEL-LUCENT , ZHANG, Yibo , TIAN, Lu , ZHAO, Yong , LANDAIS, Bruno
发明人： ZHANG, Yibo , TIAN, Lu , ZHAO, Yong , LANDAIS, Bruno
IPC分类号： H04K1/04
CPC分类号： H04W8/12 , H04W8/06 , H04W60/04 , H04W76/10
摘要： A mobile terminated call is delivered to a mobile device during an inter- VLR location update by first routing the mobile terminated call to the old mobile switching center/visitor location register (MSC/VLR), determining that the mobile device is performing a location update to a new MSC/VLR at the old MSC/VLR, and then routing the mobile terminated call to the new MSC/VLR directly from the old MSC/VLR or via the gateway mobile switching center (GMSC) for connection of the mobile terminated call to the mobile device.
摘要翻译：在VLR间位置更新期间，通过首先将移动终止的呼叫路由到旧的移动交换中心/访问位置寄存器（MSC / VLR），将移动终止的呼叫传送到移动设备，确定移动设备正在旧的MSC / VLR处对新的MSC / VLR执行位置更新，然后将移动终止的呼叫直接从旧的MSC / VLR或经由网关移动交换中心（GMSC）路由到新的MSC / VLR ）用于将移动终止的呼叫连接到移动设备。

8. 发明申请

WO2022186821A1 METHODS AND COMPOSITIONS FOR PROVIDING A PREECLAMPSIA ASSESSMENT USING LEPTIN AND CERAMIDE 审中-公开
公开(公告)号：WO2022186821A1
公开(公告)日：2022-09-09
申请号：PCT/US2021/020417
申请日：2021-03-02
申请人： MPROBE INC., , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR , LING, Bruce, Xuefeng , CHEN, Limin , COHEN, Harvey, J. , HAO, Shiying , MCELHINNEY, Doff, B. , SYLVESTER, Karl, G. , TIAN, Lu , WONG, Ronald, J. , SHAW, Gary, M. , STEVENSON, David, K.
发明人： LING, Bruce, Xuefeng , CHEN, Limin , COHEN, Harvey, J. , HAO, Shiying , MCELHINNEY, Doff, B. , SYLVESTER, Karl, G. , TIAN, Lu , WONG, Ronald, J. , SHAW, Gary, M. , STEVENSON, David, K.
IPC分类号： G01N33/68 , G01N33/53 , C12Q1/68
摘要： Preeclampsia markers, preeclampsia marker panels, and methods for obtaining a preeclampsia marker level representation for a sample are provided. These composition and methods find use in a number of applications, including, for example, diagnosing preeclampsia, prognosing preeclampsia, monitoring a subject with preeclampsia, and determining a treatment for preeclampsia. In addition, systems, devices, and kits thereof that find use in practicing the subject methods are provided.

9. 发明申请

WO2015187820A1 CMP COMPOSITIONS AND METHODS FOR POLISHING RIGID DISK SURFACES 审中-公开
标题翻译： CMP组合物和抛光刚性盘表面的方法
公开(公告)号：WO2015187820A1
公开(公告)日：2015-12-10
申请号：PCT/US2015/033964
申请日：2015-06-03
申请人： CABOT MICROELECTRONICS CORPORATION , PALANISAMY CHINNATHAMBI, Selvaraj , TIAN, Lu
发明人： PALANISAMY CHINNATHAMBI, Selvaraj , TIAN, Lu
IPC分类号： C09K3/14 , G11B5/84
CPC分类号： G11B5/8404 , C09K3/1463
摘要： A chemical mechanical polishing (CMP) method for polishing a nickel phosphorus (NiP) substrate comprises abrading a surface of the substrate with an acidic CMP composition. The CMP composition comprises a colloidal silica abrasive suspended in an aqueous carrier containing a nickel complexing agent (e.g., glycine, N-hydroxyethylenediaminetriacetic acid), polyvinyl alcohol, polystyrenesulfonic acid-co-maleic acid, and optionally an oxidizing agent.
摘要翻译：用于抛光镍磷（NiP）衬底的化学机械抛光（CMP）方法包括用酸性CMP组合物研磨衬底的表面。 CMP组合物包含悬浮在含有镍络合剂（例如甘氨酸，N-羟基乙二胺三乙酸），聚乙烯醇，聚苯乙烯磺酸 - 共 - 马来酸和任选的氧化剂的水性载体中的胶态二氧化硅磨料。

10. 发明申请

WO2011149733A2 NOVEL AMINO ALCOHOL CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY 审中-公开
标题翻译：用于OLIGUUCLEOTIDE交货的新型氨基酸醇酸饮料
公开(公告)号：WO2011149733A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/036944
申请日：2011-05-18
申请人： MERCK SHARP & DOHME CORP. , BUDZIK, Brian, W. , COLLETTI, Steven, L. , SEIFRIED, Darla Danile , STANTON, Matthew, G. , TIAN, Lu
发明人： BUDZIK, Brian, W. , COLLETTI, Steven, L. , SEIFRIED, Darla Danile , STANTON, Matthew, G. , TIAN, Lu
IPC分类号： A61K48/00 , C07C211/63
CPC分类号： A61K47/18 , A61K31/713 , C07C217/28 , C07C217/40 , C07D263/14 , C12N15/87
摘要： The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that is more efficacious than traditional cationic lipids. The present invention employs amino alcohols to enhance the efficiency of in vivo delivery of siRNA.
摘要翻译：本发明提供了可以与其它脂质组分如胆固醇和PEG-脂质组合使用以与寡核苷酸形成脂质纳米颗粒的新型阳离子脂质。本发明的目的是提供比传统阳离子脂质更有效的阳离子脂质支架。本发明使用氨基醇来提高siRNA的体内递送效率。

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