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1. 发明申请

WO03005442A3 DEVICE AND METHOD FOR MEASURING OPERATING TEMPERATURES OF AN ELECTRICAL COMPONENT 审中-公开
标题翻译：装置和方法用于测量电子部件的操作温度
公开(公告)号：WO03005442A3
公开(公告)日：2003-10-02
申请号：PCT/DE0202210
申请日：2002-06-18
申请人： BOSCH GMBH ROBERT , HAUENSTEIN HENNING , BAUR MARKUS
发明人： HAUENSTEIN HENNING , BAUR MARKUS
IPC分类号： G01R31/26 , G01R31/27 , G01K7/01
CPC分类号： G01R31/275 , G01R31/2603 , H01L2924/0002 , H01L2924/00
摘要： The invention relates to a device and method for measuring operating temperatures Tj of a component, particularly transient temperatures Tj in the breakdown region of the component (2) during a breakdown operation. A measuring device, which measures the breakdown voltage Ud and the breakdown current I of the component (2) at a specified time ti during the breakdown operation, enables the component temperature Tj at time ti to be determined by comparing measurement data with previously recorded reference measurement data.
摘要翻译：本发明提供了一种用于断开操作期间测量的工作温度TJ的成分，特别是瞬态温度TJ在组分（2）的击穿区域的装置和方法，其中，从所述击穿电压UD和击穿电流分量I（2）在一定的测定时间t的部件温度Tj在时间t可通过测量装置的击穿操作期间，通过比较预先记录的基准测量数据的测量数据来确定。

2. 发明申请

WO2012130479A2 METHOD FOR CONTROLLING A RECTIFIER 审中-公开
标题翻译：一种用于控制整流器
公开(公告)号：WO2012130479A2
公开(公告)日：2012-10-04
申请号：PCT/EP2012050010
申请日：2012-01-02
申请人： BOSCH GMBH ROBERT , MEHRINGER PAUL , SCHILLER UWE , HEINISCH HOLGER , BAUR MARKUS , KURFISS JOCHEN , WALTER GERHARD
发明人： MEHRINGER PAUL , SCHILLER UWE , HEINISCH HOLGER , BAUR MARKUS , KURFISS JOCHEN , WALTER GERHARD
CPC分类号： H02M7/219 , H02M1/32 , H02M2001/327 , H02P9/48
摘要： The invention relates to a method for controlling a rectifier comprising active switching elements (40, 42, 50, 52, 60, 62) in the event of a drop in load, wherein the active switching elements (40, 42, 50, 52, 60, 62) are controlled during the voltage clamping such that the clamping voltage behaves according to a predetermined time-dependent signal form in at least one switching branch (30, 32, 34) within at least a half-cycle of the current to be rectified.
摘要翻译：一种用于驱动具有有源开关元件的整流器的方法（40，42，50，52，60，62）提出了在一个负载下降，其中，所述有源开关元件（40，42，50，52，60，62）上的电压钳位在这样被驱动，使得在按照规定的时间相关的波形整流的电流的行为中的至少一个半周期内的至少一个开关支路（30，32，34）的钳位电压。

3. 发明申请

WO0234232A3 USE OF CAROTENOIDS FOR TREATING AGEING SYMPTOMS 审中-公开
标题翻译：使用CAROTENOIDS治疗老化症状
公开(公告)号：WO0234232A3
公开(公告)日：2002-06-27
申请号：PCT/FR0103315
申请日：2001-10-25
申请人： OREAL , BRETON LIONEL , BAUR MARKUS
发明人： BRETON LIONEL , BAUR MARKUS
IPC分类号： A23L1/30 , A61K8/00 , A61K8/30 , A61K8/31 , A61K8/36 , A61K8/368 , A61K8/49 , A61K8/67 , A61K9/48 , A61K31/015 , A61P17/00 , A61P43/00 , A61Q5/00 , A61Q19/00 , A61Q19/04 , A61Q19/08 , C12N9/99 , A61K7/48
CPC分类号： A61K8/31 , A61K8/671 , A61Q19/08
摘要： The invention concerns the use in a composition or for preparing a composition of the association of at least a carotenoid with provitamin A activity and of at least a carotenoid without provitamin A activity, the association or the composition being designed to treat cutaneous symptoms of ageing, particularly degradation of the skin and/or of mucous membranes by inhibiting the activity and/or the expression of collagenases and by increasing collagen synthesis.
摘要翻译：本发明涉及组合物中的用途或用于制备至少类胡萝卜素与前维生素A活性的缔合组合物和至少一种没有维生素A活性的类胡萝卜素的组合物，该组合物或组合物被设计用于治疗老化的皮肤症状，特别是通过抑制胶原酶的活性和/或表达以及通过增加胶原合成来降低皮肤和/或粘膜。

4. 发明申请

WO9954435A2 IMMORTALISED CELL LINES DERIVED FROM NORMAL HUMAN SKIN TISSUES 审中-公开
标题翻译：来自正常人类皮肤组织的免疫细胞系
公开(公告)号：WO9954435A2
公开(公告)日：1999-10-28
申请号：PCT/EP9902347
申请日：1999-04-07
申请人： SOC D PRODUITS NESTLE , BAUR MARKUS
发明人： BAUR MARKUS
IPC分类号： C12N15/09 , A61L27/00 , C12N1/00 , C12N5/071 , C12N5/10 , C12N
CPC分类号： C12N5/0629 , C12N2500/14 , C12N2500/38 , C12N2501/11 , C12N2503/06 , C12N2510/04
摘要： The invention concerns a cell line of human keratinocytes immortalised by at least a functional tumorigenic gene derived from a retrovirus characterised in that it is (1) non-tumorigenic, (2) preserves aptitude for differentiating and expressing proteins and enzymes which are expressed by normal differentiated keratinocytes even after a high rate of passages in tissue culture, and (3) forms a stratified and polarised epithelium comprising an ortho-keratotic stratum corneum, when cultivated in organotypical culture in a medium without serum and without feeder cell layer. The invention also concerns an improved method for immortalising human skin cells to obtain immortalised keratinocytes, characterised in that it comprises a step of infecting the keratinocytes using functional tumorigenic genes of at least two different retoviruses. The invention further concerns the use of said keratinocytes for immunologic, pharmacological, photo-toxicological and chemiotoxicological skin reactions for expressing heterologous genes and for constructing an artificial skin.
摘要翻译：本发明涉及由至少一种源自逆转录病毒的功能性致瘤基因永生化的人角质形成细胞的细胞系，其特征在于它是（1）非致瘤性的，（2）保持分化和表达蛋白质的能力和由正常即使在组织培养中传代率高时分化的角质形成细胞，以及（3）当在没有血清且没有饲养细胞层的培养基中在器官培养中培养时，形成包含角膜角化正常角质层的分层和极化上皮。本发明还涉及使人皮肤细胞永生化以获得永生化角质形成细胞的改进方法，其特征在于它包括使用至少两种不同的逆转录病毒的功能致瘤基因感染角质形成细胞的步骤。本发明还涉及所述角质形成细胞用于表达异源基因和构建人造皮肤的免疫学，药理学，光毒理学和化学毒性皮肤反应的用途。

5. 发明申请

WO0234276A3 USE OF THE ASSOCIATION OF AT LEAST A PLANT EXTRACT OF THE GENUS CAMELLIA AND OF AT LEAST A CAROTENOID 审中-公开
标题翻译：使用至少一次植物提取物的植物提取物和至少一种卡诺菌素
公开(公告)号：WO0234276A3
公开(公告)日：2002-06-20
申请号：PCT/FR0103316
申请日：2001-10-25
申请人： OREAL , BRETON LIONEL , BAUR MARKUS
发明人： BRETON LIONEL , BAUR MARKUS
IPC分类号： A61K8/31 , A61K8/96 , A61K8/97 , A61K31/01 , A61K31/015 , A61K31/07 , A61K36/00 , A61K36/82 , A61K45/06 , A61Q19/08 , A61K35/78 , A23L1/30 , A23L1/302 , A61K7/48
CPC分类号： A61K45/06 , A61K8/31 , A61K8/97 , A61K31/01 , A61K31/015 , A61K36/82 , A61Q19/08 , A61K2300/00
摘要： The invention concerns the use of the association of at least a plant extract of the genus Camellia and of at least a carotenoid to fight against collagen degradation and hence to fight against degradation of the skin and/or of mucous membranes by collagenase inhibition.
摘要翻译：本发明涉及使用至少一种山茶属植物提取物和至少一种类胡萝卜素的抗生素来抵抗胶原蛋白降解，从而与胶原酶抑制作用抵抗皮肤和/或粘膜的降解。

6. 发明申请

WO0234233A3 USE OF AN ASSOCIATION OF A CAROTENOID AND OF AN ISOFLAVONOID FOR TREATING CUTANEOUS SYMPTOMS OF AGEING 审中-公开
标题翻译：用于治疗老年青少年症状的卡诺菌素和异氟醚的联合使用
公开(公告)号：WO0234233A3
公开(公告)日：2002-08-29
申请号：PCT/FR0103319
申请日：2001-10-25
申请人： OREAL , BRETON LIONEL , BAUR MARKUS , LIVIERO CHRISTEL
发明人： BRETON LIONEL , BAUR MARKUS , LIVIERO CHRISTEL
IPC分类号： A61K8/67 , A61K8/00 , A61K8/11 , A61K8/31 , A61K8/33 , A61K8/49 , A61K8/97 , A61K31/015 , A61K31/07 , A61K31/35 , A61K31/353 , A61K31/7048 , A61P17/00 , A61P43/00 , A61Q19/00 , A61Q19/08 , A61K7/48
CPC分类号： A61Q19/08 , A61K8/31 , A61K8/498 , A61K8/97
摘要： The invention concerns the use in a composition or for preparing a composition of the association of at least a carotenoid and at least an isoflavonoid, the association or the composition being designed to treat cutaneous symptoms of ageing, particularly degradation of the skin and/or of mucous membranes by inhibiting the activity and/or the expression of collagenases and by increasing collagen synthesis.
摘要翻译：本发明涉及在组合物中的用途或用于制备至少类胡萝卜素和至少异黄酮的缔合组合物，所述组合物或组合物被设计用于治疗皮肤老化症状，特别是皮肤退化和/或通过抑制胶原酶的活性和/或表达以及通过增加胶原合成来实现粘膜。

7. 发明申请

WO0234231A3 USE OF THE ASSOCIATION OF AT LEAST AN PLANT EXTRACT OF GENUS ROSMARINUS AND OF AT LEAST A CAROTENOID 审中-公开
标题翻译：使用至少一种植物提取物和至少一种类胡萝卜素的协会
公开(公告)号：WO0234231A3
公开(公告)日：2002-06-27
申请号：PCT/FR0103314
申请日：2001-10-25
申请人： OREAL , BRETON LIONEL , BAUR MARKUS
发明人： BRETON LIONEL , BAUR MARKUS
IPC分类号： A23L1/30 , A61K8/00 , A61K8/30 , A61K8/31 , A61K8/67 , A61K8/96 , A61K8/97 , A61K9/08 , A61K9/10 , A61K9/20 , A61K9/28 , A61K9/48 , A61K31/015 , A61K31/07 , A61K31/355 , A61K31/375 , A61K36/00 , A61K36/18 , A61P17/16 , A61P43/00 , A61Q5/00 , A61Q5/02 , A61Q19/00 , A61Q19/08 , A61K7/48
CPC分类号： A61Q19/08 , A61K8/31 , A61K8/671 , A61K8/97 , A61Q5/02 , A61Q19/00
摘要： The invention concerns the use of the association of at least a plant extract of genus Rosmarinus and of at least a carotenoid for fighting against collagen degradation, hence against degradation of the skin and/or mucous membranes by collagenase inhibition
摘要翻译：本发明涉及至少一种迷迭香属（Rosmarinus）植物提取物和至少一种类胡萝卜素的缔合物用于对抗胶原降解，由此防止胶原酶抑制引起的皮肤和/或粘膜降解

8. 发明申请

WO0234210A2 USE OF THE ASSOCIATION OF AT LEAST A CAROTENOID AND VITAMIN C FOR TREATING CUTANEOUS SYMPTOMS OF AGEING 审中-公开
标题翻译：使用至少一种类胡萝卜素和维生素C治疗老年性皮肤病症状
公开(公告)号：WO0234210A2
公开(公告)日：2002-05-02
申请号：PCT/FR0103318
申请日：2001-10-25
申请人： OREAL , BRETON LIONEL , BAUR MARKUS
发明人： BRETON LIONEL , BAUR MARKUS
IPC分类号： A61K8/31 , A61K8/67 , A61Q19/04 , A61Q19/08 , A61K7/00
CPC分类号： A61K8/31 , A61K8/676 , A61Q19/08
摘要： The invention concerns the use in a composition or for preparing a composition of the association of at least a carotenoid and vitamin C, the association or the composition being designed to treat cutaneous symptoms of ageing, in particular degradation of the skin and/or of mucous membranes by inhibiting the activity and/or the expression of collagenases and by increasing collagen synthesis.
摘要翻译：本发明涉及用于组合物或用于制备至少类胡萝卜素与维生素C缔合的组合物，所述缔合或组合物被设计用于治疗皮肤衰老症状，特别是皮肤和/或粘膜的降解通过抑制胶原酶的活性和/或表达以及通过增加胶原合成来实现。

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