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1. 发明申请

WO2008122459A2 RELIABILITY OF A DIGITAL SYSTEM 审中-公开
标题翻译：数字系统的可靠性
公开(公告)号：WO2008122459A2
公开(公告)日：2008-10-16
申请号：PCT/EP2008/052021
申请日：2008-02-19
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , IBM UNITED KINGDOM LIMITED , KIM, Dae, Ik , KIM, Jonghae , KIM, Moon, Ju , MOULIC, James, Randal , SONG, Hong, Hua
发明人： KIM, Dae, Ik , KIM, Jonghae , KIM, Moon, Ju , MOULIC, James, Randal , SONG, Hong, Hua
IPC分类号： G06F11/00
CPC分类号： G06F11/008
摘要： Method, system and computer program are provided for continually monitoring reliability of a digital system and for issuing a warning signal if digital system operation degrades to or past a specified threshold. The technique includes periodically determining a maximum frequency of operation of the digital system, and generating a warning signal indicative of a reliability degradation of the digital system if at least one of: (i) a measured or estimated maximum frequency of operation of the digital system is below a warning threshold frequency of operation of the digital system, wherein the warning threshold frequency is greater than or equal to a manufacturer specified minimum frequency of operation for the digital system; or (ii) a rate of change in the difference between measured maximum frequencies of operation of the digital system exceeds an acceptable rate of change threshold for the digital system.
摘要翻译：提供了方法，系统和计算机程序，用于连续监视数字系统的可靠性，并且如果数字系统操作降级到或超过指定阈值，则发出警告信号。该技术包括周期性地确定数字系统的最大操作频率，以及产生指示数字系统的可靠性劣化的警告信号，如果以下至少一个：（i）数字系统的测量或估计的最大操作频率低于数字系统的警告阈值操作频率，其中警告阈值频率大于或等于制造商规定的数字系统的最小操作频率; 或者（ii）数字系统的测量的最大操作频率之间的差异的变化率超过数字系统的可接受的变化率阈值。

2. 发明申请

WO2008079569A3 SYSTEM AND METHOD FOR DETERMINING AMOUNT OF RADIOACTIVE MATERIAL TO ADMINISTER TO A PATIENT 审中-公开
公开(公告)号：WO2008079569A3
公开(公告)日：2008-07-03
申请号：PCT/US2007/085400
申请日：2007-11-21
申请人： THE JOHNS HOPKINS UNIVERSITY , SGOUROS, George , SONG, Hong , PRIDEAUX, Andrew , HOBBS, Robert
发明人： SGOUROS, George , SONG, Hong , PRIDEAUX, Andrew , HOBBS, Robert
IPC分类号： G01N33/48
摘要： In one embodiment, a computerized system and method are provided for determining an optimum amount of radioactivity to administer to a patient, comprising: assuming an activity retention limit; utilizing the activity retention limit to determine a dose rate for a phantom category; utilizing the dose rate for the phantom category to determine the dose rate for a second phantom category; and utilizing the dose rate for a second phantom category to find information regarding the second phantom category. In other embodiments, a computerized system and method are provided for determining an optimum amount of radioactivity to administer to a patient, comprising: obtaining at least one image relating to anatomy of a particular patient; obtaining multiple images regarding radioactivity distribution over time in the particular patient; combining the radioactivity images with the anatomy images; running a Monte Carlo simulation to obtain dose image information; and using the dose image information to obtain BED and/or EUD information.

3. 发明申请

WO2010076914A1 METHOD OF PREPARING DICHLOROPROPANOL USING GLYCEROL WITH IMPROVED SELECTIVITY FOR DICHLOROPROPANOL 审中-公开
标题翻译：使用甘油的二氯丙醇的制备方法对二氯丙醇具有改进的选择性
公开(公告)号：WO2010076914A1
公开(公告)日：2010-07-08
申请号：PCT/KR2009/000770
申请日：2009-02-18
申请人： SAMSUNG FINE CHEMICALS CO., LTD. , SONG, Won Seob , WOO, Sung Yul , SONG, Boo Weon , PARK, Seong Han , PARK, Sung Jin , SONG, Hong Tae , KWON, Myoung Suk
发明人： SONG, Won Seob , WOO, Sung Yul , SONG, Boo Weon , PARK, Seong Han , PARK, Sung Jin , SONG, Hong Tae , KWON, Myoung Suk
IPC分类号： C07C29/62
CPC分类号： C07D301/26 , C07C29/62 , C07C31/36
摘要： Provided is a method of preparing dichloropropanol using glycerol. The method includes: chlorination of glycerol including a plurality of chlorination reaction stages using a catalyst; and a water-removing stage performed between the reaction stages, independently of the reaction stages.
摘要翻译：提供使用甘油制备二氯丙醇的方法。该方法包括：使用催化剂氯化甘油包括多个氯化反应阶段; 在反应阶段之间进行脱水阶段，独立于反应阶段。

4. 发明申请

WO2009111088A3 ANTITUMOR IMMUNIZATION BY LIPOSOMAL DELIVERY OF VACCINE TO THE SPLEEN 审中-公开
公开(公告)号：WO2009111088A3
公开(公告)日：2009-09-11
申请号：PCT/US2009/030039
申请日：2009-01-02
申请人： THE JOHNS HOPKINS UNIVERSITY , SGOUROS, George , SONG, Hong , LINGAPPA, Mohanambe
发明人： SGOUROS, George , SONG, Hong , LINGAPPA, Mohanambe
IPC分类号： A61K9/127 , A61P35/00 , A61K39/00 , A61K39/39 , A61K48/00 , A61K39/385
摘要： The present invention relates to methods for preventing, reducing or treating a variety of conditions, including cancer, and vaccines, compositions and liposomes used to elicit or amplify an immune response specific to the condition by delivering to the spleen of an individual a pegylated liposome construct having a diameter of greater than about 300 nm and including a therapeutic agent and an adjuvant for eliciting or amplifying the immune response.

5. 发明申请

WO2009104827A1 METHOD AND APPARATUS FOR GENERATING KEY STREAM FOR STREAM CIPHER, S-BOX FOR BLOCK CIPHER AND METHOD FOR SUBSTITUTING INPUT VECTOR USING THE S-BOX 审中-公开
标题翻译：用于生成流水槽的主流的方法和装置，用于块式油的S型箱的方法和装置以及使用S型箱取代输入矢量的方法
公开(公告)号：WO2009104827A1
公开(公告)日：2009-08-27
申请号：PCT/KR2008/000996
申请日：2008-02-20
申请人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY , SONG, Hong-Yeop , KIM, Ju-Young
发明人： SONG, Hong-Yeop , KIM, Ju-Young
IPC分类号： H04L9/18 , H04K1/00
CPC分类号： H04L9/0631 , H04L9/0662 , H04L9/12
摘要： The present invention discloses a method and an apparatus for generating a key stream for a stream cipher, an S-box for a block cipher and a method for substituting an input vector using the S-box. According to the present invention, there is provided a method for generating a key stream for a stream encryption, comprising: receiving a vector that represents each state value of n(2≤n≤N) stages from an N-stage linear feedback shift register (LFSR) that generates a pseudo¬ random binary sequence; and outputting a key stream using a logarithmic function over a finite field having a primitive element of the finite field corresponding to a vector space that represents the vector as a base. With the present invention, high nonlinearity and optimal algebraic immunity can be obtained.
摘要翻译：本发明公开了一种用于生成用于流密码的密钥流的方法和装置，用于块密码的S盒和使用S盒替代输入向量的方法。根据本发明，提供了一种用于生成用于流加密的密钥流的方法，包括：从N级线性反馈移位寄存器接收表示n（2 = n = N）级的每个状态值的向量（LFSR），其生成伪随机二进制序列; 并且使用对数函数在有限域上输出密钥流，该有限域具有对应于表示该向量作为基础的向量空间的有限域的原始元素。利用本发明，可以获得高非线性和最优代数免疫。

6. 发明申请

WO2008079569A9 SYSTEM AND METHOD FOR DETERMINING AMOUNT OF RADIOACTIVE MATERIAL TO ADMINISTER TO A PATIENT 审中-公开
标题翻译：用于确定放射性物质量给予患者的系统和方法
公开(公告)号：WO2008079569A9
公开(公告)日：2008-08-28
申请号：PCT/US2007085400
申请日：2007-11-21
申请人： UNIV JOHNS HOPKINS , SGOUROS GEORGE , SONG HONG , PRIDEAUX ANDREW , HOBBS ROBERT
发明人： SGOUROS GEORGE , SONG HONG , PRIDEAUX ANDREW , HOBBS ROBERT
IPC分类号： A61B6/03
CPC分类号： A61N5/1031 , A61B6/032 , A61B6/037 , A61B6/5217 , A61N5/1039 , A61N2005/1089
摘要： In one embodiment, a computerized system and method are provided for determining an optimum amount of radioactivity to administer to a patient, comprising: assuming an activity retention limit; utilizing the activity retention limit to determine a dose rate for a phantom category; utilizing the dose rate for the phantom category to determine the dose rate for a second phantom category; and utilizing the dose rate for a second phantom category to find information regarding the second phantom category. In other embodiments, a computerized system and method are provided for determining an optimum amount of radioactivity to administer to a patient, comprising: obtaining at least one image relating to anatomy of a particular patient; obtaining multiple images regarding radioactivity distribution over time in the particular patient; combining the radioactivity images with the anatomy images; running a Monte Carlo simulation to obtain dose image information; and using the dose image information to obtain BED and/or EUD information.
摘要翻译：在一个实施例中，提供了一种计算机化系统和方法，用于确定向患者施用的放射性的最佳量，包括：假设活动保持极限; 利用活动保留极限来确定幻影类别的剂量率; 利用幻影类别的剂量率来确定第二个幻影类别的剂量率; 并且利用第二体模类别的剂量率来找到关于第二体模类别的信息。在其他实施例中，提供了一种计算机化系统和方法，用于确定对患者施用的放射性的最佳量，包括：获得与特定患者的解剖结构相关的至少一个图像; 在特定患者中获得关于随时间的放射性分布的多个图像; 将放射性图像与解剖图像组合; 运行蒙特卡罗模拟以获得剂量图像信息; 并使用剂量图像信息获得BED和/或EUD信息。

7. 发明申请

WO2008049700A1 MULTIMODE COMMUNICATION TERMINAL AND MULTIMODE COMMUNICATION IMPLEMENTATION METHOD 审中-公开
标题翻译：多模通信终端和多模通信实现方法
公开(公告)号：WO2008049700A1
公开(公告)日：2008-05-02
申请号：PCT/EP2007/059888
申请日：2007-09-19
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , IBM UNITED KINGDOM LIMITED , LIN, Yonghua , SONG, Hong, Hua , YANG, Yudong , YUAN, Yu , ZHOU, You
发明人： LIN, Yonghua , SONG, Hong, Hua , YANG, Yudong , YUAN, Yu , ZHOU, You
IPC分类号： H04B1/40 , H04B7/04
CPC分类号： H04B7/0689 , H04B1/0064 , H04B1/406 , H04B7/0871
摘要： The present invention provides a multimode communication terminal which contains at least a first separate channel module and a second separate channel module. The multimode communication terminal can be configured to communicate by using the first channel module and/or the second channel module. The channel modules communicate according to different communication protocols. The multimode communication terminal further comprises: channel switch layer means for switching the first channel module to have parameter characteristics consistent with those of the second channel module, so that the multimode communication terminal enables the MIMO operation mode by using the first channel module and the second channel module at the same time. The present invention further provides a method for enabling a MIMO operation mode in a multimode communication terminal. By using a relatively small number of RF communication modules, the present invention implements a wireless mobile multimode communication terminal which enables various operation modes including the MIMO operation mode. Compared with the existing solutions, the present invention greatly reduces the size required by the terminal.
摘要翻译：本发明提供了一种多模通信终端，其包含至少第一单独的信道模块和第二单独的信道模块。多模通信终端可以被配置为通过使用第一信道模块和/或第二信道模块进行通信。信道模块根据不同的通信协议进行通信。多模通信终端还包括：信道切换层装置，用于切换第一信道模块以具有与第二信道模块一致的参数特性，使得多模通信终端通过使用第一信道模块和第二信道模块启用MIMO操作模式通道模块。本发明还提供一种在多模通信终端中实现MIMO操作模式的方法。通过使用相对较少的RF通信模块，本发明实现了一种无线移动多模通信终端，其能够实现包括MIMO操作模式的各种操作模式。与现有方案相比，本发明大大降低了终端所需的尺寸。

8. 发明申请

WO2005028447A1 BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS 审中-公开
标题翻译：苯并咪唑衍生物：制剂和药物应用
公开(公告)号：WO2005028447A1
公开(公告)日：2005-03-31
申请号：PCT/SG2004/000307
申请日：2004-09-21
申请人： S*BIO PTE LTD , CHEN, Dizhong , DENG, WeiPing , SANGTHONGPITAG, Kanda , SONG, Hong Yan , SUN, Eric, T. , YU, Niefang , ZOU, Yong
发明人： CHEN, Dizhong , DENG, WeiPing , SANGTHONGPITAG, Kanda , SONG, Hong Yan , SUN, Eric, T. , YU, Niefang , ZOU, Yong
IPC分类号： C07D235/06
CPC分类号： A61K31/4184 , A61K31/4439 , A61K31/444 , A61K31/454 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , C04B35/632 , C07D235/06 , C07D235/08 , C07D235/14 , C07D235/18 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/02 , C07D403/06 , C07D409/04 , C07D413/02 , G01N33/5011 , G01N33/6875 , Y02A50/409 , Y02A50/411 , Y02A50/414
摘要： The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
摘要翻译：本发明涉及作为组蛋白脱乙酰酶抑制剂的异羟肟酸酯化合物。更具体地说，本发明涉及含苯并咪唑的化合物及其制备方法。这些化合物可用作治疗增殖性疾病以及涉及组蛋白脱乙酰酶（HDAC）的调节异常或与其相关的其它疾病的药物。

9. 发明申请

WO2008122459A3 MONITORING RELIABILITY OF A DIGITAL SYSTEM 审中-公开
标题翻译：监测数字系统的可靠性
公开(公告)号：WO2008122459A3
公开(公告)日：2008-11-27
申请号：PCT/EP2008052021
申请日：2008-02-19
申请人： IBM , IBM UK , KIM DAE IK , KIM JONGHAE , KIM MOON JU , MOULIC JAMES RANDAL , SONG HONG HUA
发明人： KIM DAE IK , KIM JONGHAE , KIM MOON JU , MOULIC JAMES RANDAL , SONG HONG HUA
IPC分类号： G06F11/00
CPC分类号： G06F11/008
摘要： Method, system and computer program are provided for continually monitoring reliability of a digital system and for issuing a warning signal if digital system operation degrades to or past a specified threshold. The technique includes periodically determining a maximum frequency of operation of the digital system, and generating a warning signal indicative of a reliability degradation of the digital system if at least one of: (i) a measured or estimated maximum frequency of operation of the digital system is below a warning threshold frequency of operation of the digital system, wherein the warning threshold frequency is greater than or equal to a manufacturer specified minimum frequency of operation for the digital system; or (ii) a rate of change in the difference between measured maximum frequencies of operation of the digital system exceeds an acceptable rate of change threshold for the digital system.
摘要翻译：提供了方法，系统和计算机程序，用于连续监视数字系统的可靠性，并且如果数字系统操作降级到或超过指定阈值，则发出警告信号。该技术包括周期性地确定数字系统的最大操作频率，以及产生指示数字系统的可靠性劣化的警告信号，如果以下至少一个：（i）数字系统的测量或估计的最大操作频率低于数字系统的警告阈值操作频率，其中警告阈值频率大于或等于制造商规定的数字系统的最小操作频率; 或者（ii）数字系统的测量的最大操作频率之间的差异的变化率超过数字系统的可接受的变化率阈值。

10. 发明申请

WO2008079569A2 SYSTEM AND METHOD FOR DETERMINING AMOUNT OF RADIOACTIVE MATERIAL TO ADMINISTER TO A PATIENT 审中-公开
标题翻译：用于确定放射性物质的量以向患者施用的系统和方法
公开(公告)号：WO2008079569A2
公开(公告)日：2008-07-03
申请号：PCT/US2007085400
申请日：2007-11-21
申请人： UNIV JOHNS HOPKINS , SGOUROS GEORGE , SONG HONG , PRIDEAUX ANDREW , HOBBS ROBERT
发明人： SGOUROS GEORGE , SONG HONG , PRIDEAUX ANDREW , HOBBS ROBERT
IPC分类号： A61B6/03
CPC分类号： A61N5/1031 , A61B6/032 , A61B6/037 , A61B6/5217 , A61N5/1039 , A61N2005/1089
摘要： In one embodiment, a computerized system and method are provided for determining an optimum amount of radioactivity to administer to a patient, comprising: assuming an activity retention limit; utilizing the activity retention limit to determine a dose rate for a phantom category; utilizing the dose rate for the phantom category to determine the dose rate for a second phantom category; and utilizing the dose rate for a second phantom category to find information regarding the second phantom category. In other embodiments, a computerized system and method are provided for determining an optimum amount of radioactivity to administer to a patient, comprising: obtaining at least one image relating to anatomy of a particular patient; obtaining multiple images regarding radioactivity distribution over time in the particular patient; combining the radioactivity images with the anatomy images; running a Monte Carlo simulation to obtain dose image information; and using the dose image information to obtain BED and/or EUD information.
摘要翻译：在一个实施方案中，提供了计算机化的系统和方法用于确定施用于患者的放射性的最佳量，包括：假设活性保留限度; 利用活动保留限制来确定幻影类别的剂量率; 利用幻像类别的剂量率来确定第二幻象类别的剂量率; 以及利用第二幻影类别的剂量率来找到关于第二幻影类别的信息。在其他实施方案中，提供了计算机化的系统和方法，用于确定施用于患者的放射性的最佳量，包括：获得与特定患者的解剖结构相关的至少一个图像; 在特定患者中获得关于随时间的放射性分布的多个图像; 将放射性图像与解剖图像组合; 运行蒙特卡洛模拟以获得剂量图像信息; 并使用剂量图像信息来获得BED和/或EUD信息。

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